Themed collection 2019 International Open Access Week Collection
Fluorescent probes for organelle-targeted bioactive species imaging
The dynamic fluctuations of bioactive species in living cells are associated with numerous physiological and pathological phenomena. The emergence of organelle-targeted fluorescent probes has significantly facilitated our understanding on the biological functions of these species. This review describes the design, applications, challenges and potential directions of organelle-targeted bioactive species probes.
Visual kinetic analysis
Naked-eye comparison of reaction profiles is a powerful tool to extract mechanistic information – FAQ, video tutorial and templated examples included.
A review on graphene-based nanocomposites for electrochemical and fluorescent biosensors
Biosensors with high sensitivity, selectivity and a low limit of detection, reaching nano/picomolar concentrations of biomolecules, are important to the medical sciences and healthcare industry for evaluating physiological and metabolic parameters.
Carbon quantum dots and their biomedical and therapeutic applications: a review
The biomedical applications of the recently emerging carbon quantum dots are reviewed.
Scope of organometallic compounds based on transition metal-arene systems as anticancer agents: starting from the classical paradigm to targeting multiple strategies
The advent of the clinically approved drug cisplatin started a new era in the design of metallodrugs for cancer chemotherapy.
Green synthesis of silver nanoparticles: biomolecule-nanoparticle organizations targeting antimicrobial activity
In this review, we discuss the recent advances in green synthesis of silver nanoparticles, their application as antimicrobial agents and mechanism of antimicrobial mode of action.
Arylhydrazines: novel and versatile electrophilic partners in cross-coupling reactions
Arylhydrazines are extremely valuable compounds in organic chemistry that are widely used for the synthesis of a variety of biologically active molecules such as indoles, indazoles, pyrazoles, aryltriazoles, β-lactams and quinazolines.
Adsorptive environmental applications of MXene nanomaterials: a review
Due to their large specific surface area and abundant active surficial sites, MXenes can adsorb various environmental pollutants.
Advancements in six-membered cyclic carbonate (1,3-dioxan-2-one) synthesis utilizing carbon dioxide as a C1 source
This review article surveys literature methods for the synthesis of six-membered cyclic carbonates using various substrates in the presence of CO2 with special emphasis on the mechanistic aspects of the reactions.
A short review of recent advances in CO2 hydrogenation to hydrocarbons over heterogeneous catalysts
CO2 hydrogenation to hydrocarbons over heterogeneous catalysts.
A functional chitosan-based hydrogel as a wound dressing and drug delivery system in the treatment of wound healing
Functional active wound dressings are expected to provide a moist wound environment, offer protection from secondary infections, remove wound exudate and accelerate tissue regeneration, as well as to improve the efficiency of wound healing.
A molecular design strategy toward enzyme-activated probes with near-infrared I and II fluorescence for targeted cancer imaging
A molecular design strategy is established to access diverse enzyme-activated probes that are excitable and emit in the NIR (I and II) region with favorable Stokes shifts, enabling targeted cancer imaging by real-time monitoring enzyme activities.
Plasmonic colloidosomes of black gold for solar energy harvesting and hotspots directed catalysis for CO2 to fuel conversion
Plasmonic black gold converts CO2 to methane using solar energy.
Nickel-catalyzed C–N bond activation: activated primary amines as alkylating reagents in reductive cross-coupling
The reductive cross coupling of pyridinium salts derived from readily available primary alkyl amines with aryl halides has been achieved under mild reaction conditions using a nickel catalyst.
Desulfonative photoredox alkylation of N-heteroaryl sulfones – an acid-free approach for substituted heteroarene synthesis
Photoredox-mediated alkylation of heteroaryl sulfones under redox-neutral, acid-free conditions to create drug-like molecules.
Symmetry breaking and the turn-on fluorescence of small, highly strained carbon nanohoops
By breaking the centrosymmetry of the structure, the most strained carbon nanohoops become fluorescent as predicted by optical selection rules.
Controlled growth of imine-linked two-dimensional covalent organic framework nanoparticles
Highly crystalline, monodisperse, imine-linked covalent organic framework nanoparticles were obtained under Sc(OTf)3-catalyzed conditions and enlarged by a slow monomer addition technique that prevents secondary nucleation.
Color-tunable lanthanide metal–organic framework gels
MOF gels with intrinsic emission color are prepared with 5-boronoisophthalic acid and Eu3+, Tb3+, and/or Dy3+. Single-metal gels exhibit trichromatic fluorescence, so full color emissions are readily obtained by tuning the type and/or ratio of Ln3+ ions to prepare mixed-metal gels. Nano-ribbons form from the precursors and then entangle together to generate the gels.
Unusual fcc-structured Ag10 kernels trapped in Ag70 nanoclusters
A bioctahedral Ag10 kernel is locked by a pair of Mo7O2610− anions to form an inner Ag10@(Mo7O26)2 core which is further encapsulated by an outer Ag70 shell to form three-shell Ag10@(Mo7O26)2@Ag70 nanoclusters.
Site-selective protein conjugation at histidine
Site-selective conjugation generally requires both (i) molecular engineering of the protein of interest to introduce a conjugation site at a defined location and (ii) a site-specific conjugation technology.
Metal-free, intermolecular carbopyridylation of alkenes via visible-light-induced reductive radical coupling
An efficient, metal-free strategy for the intermolecular three-component carbopyridylation of styrenes, enabled by Hantzsch ester and visible light, has been described.
Selective C–H halogenation over hydroxylation by non-heme iron(IV)-oxo
Synthetic non-heme iron-oxo and iron-halide complexes promote selective halogenation of the sp3-C–H bonds via hydrogen atom abstraction and halide rebound phenomenon.
Large-scale comparison of machine learning methods for drug target prediction on ChEMBL
The to date largest comparative study of nine state-of-the-art drug target prediction methods finds that deep learning outperforms all other competitors. The results are based on a benchmark of 1300 assays and half a million compounds.
A porous, electrically conductive hexa-zirconium(IV) metal–organic framework
Electrical conductivity is engendered in a pyrene containing hexa-zirconium(IV) metal–organic framework by physically encapsulating fullerenes within MOF cavity.
A thioether-directed palladium-cleavable linker for targeted bioorthogonal drug decaging
We describe the development of a bifunctional linker that simultaneously allows site-specific protein modification and palladium-mediated bioorthogonal decaging.
Transition-metal-free decarboxylative bromination of aromatic carboxylic acids
Aromatic acids are converted into aryl bromides simply and efficiently via decarboxylation providing new depth and insight into Hunsdiecker-type reactivity.
Rational design of a water-soluble NIR AIEgen, and its application in ultrafast wash-free cellular imaging and photodynamic cancer cell ablation
The first water-soluble NIR AIEgen was synthesized and used for ultrafast wash-free cellular imaging and photodynamic cancer cell ablation.
Fluorescent dyes and probes for super-resolution microscopy of microtubules and tracheoles in living cells and tissues
Nanoscopy compatible fluorescent tubulin probes can be used to stain microtubules and chitin-rich taenidia in the insect tracheoles.
MoleculeNet: a benchmark for molecular machine learning
A large scale benchmark for molecular machine learning consisting of multiple public datasets, metrics, featurizations and learning algorithms.
Black titania nanotubes/spongy graphene nanocomposites for high-performance supercapacitors
A simple method is demonstrated to prepare functionalized spongy graphene/hydrogenated titanium dioxide (FG-HTiO2) nanocomposites as interconnected, porous 3-dimensional (3D) network crinkly sheets.
Strain-enhanced properties of van der Waals heterostructure based on blue phosphorus and g-GaN as a visible-light-driven photocatalyst for water splitting
Many strategies have been developed to overcome the critical obstacles of fast recombination of photogenerated charges and the limited ability of semiconductor photocatalysts to absorb visible light.
Monolayer black phosphorus by sequential wet-chemical surface oxidation
We report a straightforward chemical methodology for controlling the thickness of black phosphorus flakes down to the monolayer limit by layer-by-layer oxidation and thinning, using water as solubilizing agent.
Solid-state AIEnh-circularly polarised luminescence of chiral perylene diimide fluorophores
Chiral N,N′-bis(1-phenylethyl)perylene-3,4,9,10-tetracarboxylic acid diimide (BPP) exhibits solid-state aggregation-induced enhanced circularly polarized luminescence (AIEnh-CPL) in KBr, PMMA, and myo-IPU matrices..
Effect of external electric field on nanobubbles at the surface of hydrophobic particles during air flotation
In this paper, the effect of external electric field on nanobubbles adsorbed on the surface of hydrophobic particles during air flotation was studied by molecular dynamics simulations.
Kinetics, equilibrium, statistical surface modeling and cost analysis of paraquat removal from aqueous solution using carbonated jujube seed
This paper reports the removal of paraquat from an aqueous solution using prepared carbonated jujube seed (JS/HSO-700).
Facile solvothermal preparation of Fe3O4–Ag nanocomposite with excellent catalytic performance
A new Fe3O4–Ag nanocomposite was prepared via solvothermal method, demonstrating potential application in catalytic degradation of wastewater treatment and composite materials.
A water-stable luminescent metal–organic framework for effective detection of aflatoxin B1 in walnut and almond beverages
Sensitive and rapid detection of aflatoxin B1 (AFB1) without using antibody or biomolecular modifications in water is achieved using a novel water-stable luminescent metal–organic framework (LMOF) termed Zr-CAU-24.
Predicting the electrical conductivity in polymer carbon nanotube nanocomposites based on the volume fractions and resistances of the nanoparticle, interphase, and tunneling regions in conductive networks
Some limited models have been suggested to determine the conductivity of polymer carbon nanotube (CNT) nanocomposites (PCNTs).
Improved performance of optical phased arrays assisted by transparent graphene nanoheaters and air trenches
Improved performances of optical phased arrays have been achieved assisted by graphene nanoheaters and air trenches.
Sulfonated graphene oxide/Nafion composite membranes for high temperature and low humidity proton exchange membrane fuel cells
Preparation process of Nafion/Fe3O4–SGO composite membranes.
Paclitaxel prodrug based mixed micelles for tumor-targeted chemotherapy
Paclitaxel prodrug based mixed micelles with high drug loading and tumor targeting capacity for elevated chemotherapy.
About this collection
In celebration of International Open Access Week 2019 we have drawn together some of our most popular papers from the last couple of years for you to enjoy. The cross-journal collection highlights the breadth of topics and high quality work that is published in Chemical Science and RSC Advances and they are of course free to read! Chemical Science and RSC Advances are proud to be fully Open Access journals.