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Themed collection Coronavirus articles - free to access collection

195 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

Brian Pecson and Daniel Gerrity present an Editorial Perspective which focuses on the impact of SARS-CoV-2 on the water industry.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

Vincenzo Naddeo and Haizhou Liu present an ‘Editorial Perspective’ on coronavirus in wastewater and discuss the water research needs to combat viral outbreaks.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Highlight

Nano- and biosensors for the detection of SARS-CoV-2: challenges and opportunities

Recent advances in the design of nano- and biosensors, as well as important challenges and opportunities related to the detection of SARS-CoV-2 and COVID-19 diagnosis, are discussed.

Graphical abstract: Nano- and biosensors for the detection of SARS-CoV-2: challenges and opportunities
Perspective

The latest strategies in the fight against the COVID-19 pandemic: the role of metal and metal oxide nanoparticles

In this review, we summarize and highlight the latest achievements based on nanoparticles in the fight against COVID-19.

Graphical abstract: The latest strategies in the fight against the COVID-19 pandemic: the role of metal and metal oxide nanoparticles
Perspective

Envisioned strategy for an early intervention in virus-suspected patients through non-invasive piezo- and pyro-electric-based wearable sensors

This perspective explores the scope of piezo- and pyro-electric wearable sensors towards the early intervention of virus-affected patients, particularly in the context of the ongoing COVID-19 pandemic.

Graphical abstract: Envisioned strategy for an early intervention in virus-suspected patients through non-invasive piezo- and pyro-electric-based wearable sensors
Open Access Perspective

Soft matter science and the COVID-19 pandemic

Much of the science underpinning the global response to the COVID-19 pandemic lies in the soft matter domain.

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

The appearance of new and lethal viruses and their potential threat urgently requires innovative antiviral systems.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Ultraviolet germicidal irradiation is one method for decontamination of N-95 filtering facepiece respirators to facilitate reuse during the COVID-19 pandemic. Other techniques include hydrogen peroxide vaporization, microwave-generated steaming, and dry heating.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

With its principles discovered more than a hundred years ago the photodynamic inactivation of viruses is now routinely employed in the decontamination of blood products but also investigated for HPV treatment and water disinfection and food safety.

Graphical abstract: Trends and targets in antiviral phototherapy
Open Access Frontier

Growth of Legionella during COVID-19 lockdown stagnation

While “avoiding stagnation” has been the mantra of building water experts, support for how this terminology is used is not overly convincing. Carefully nuanced COVID stagnation studies can improve water quality research and communication strategies.

Graphical abstract: Growth of Legionella during COVID-19 lockdown stagnation
Minireview

An overview of molecular biology and nanotechnology based analytical methods for the detection of SARS-CoV-2: promising biotools for the rapid diagnosis of COVID-19

Molecular biology and nanotechnology based analytical methods have proven to be promising diagnostic tools for the rapid diagnosis of COVID-19.

Graphical abstract: An overview of molecular biology and nanotechnology based analytical methods for the detection of SARS-CoV-2: promising biotools for the rapid diagnosis of COVID-19
From the themed collection: Analyst Recent HOT articles
Minireview

The role of biomaterials and three dimensional (3D) in vitro tissue models in fighting against COVID-19

Biomaterials in company with bioengineered tissue models enables scientists to develop the more precise disease models and find better solutions in infectious respiratory disease treatment.

Graphical abstract: The role of biomaterials and three dimensional (3D) in vitro tissue models in fighting against COVID-19
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

Multiplex lateral flow immunoassays for outstanding POCT of infectious diseases.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

Biosensors function as rapid, sensitive and specific diagnostic tools for various viral infectious diseases.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

Recent developments in the biological activities of polyoxometalates (metal-oxide cluster anions) are discussed from the chemotherapeutic point of view for a novel inorganic drug.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Review Article

SARS-CoV-2 and tissue damage: current insights and biomaterial-based therapeutic strategies

Schematic representation of use of biomaterials in tissue regeneration for SARS-CoV-2-affected organs.

Graphical abstract: SARS-CoV-2 and tissue damage: current insights and biomaterial-based therapeutic strategies
Open Access Review Article

Targeting the SARS-CoV-2-spike protein: from antibodies to miniproteins and peptides

Fighting COVID-19 with high affinity reagents: this review article summarizes the discovery of several classes of (bio) molecules targeting the SARS-CoV-2 spike protein.

Graphical abstract: Targeting the SARS-CoV-2-spike protein: from antibodies to miniproteins and peptides
Open Access Review Article

The chemical biology of coronavirus host–cell interactions

Chemical biology strategies can play important roles in studying the complexity of SARS-CoV-2–host interactions at molecular level detail.

Graphical abstract: The chemical biology of coronavirus host–cell interactions
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

SARS-CoV-2 virus invades the host through angiotensin-converting enzyme 2 (ACE2) receptors by decreasing the ACE2 expression of the host.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Summary of the latest research progress on detection methods of SARS-CoV-2, providing a reference to develop rapid and accurate diagnostic strategies for COVID-19.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

Since the coronaviruses that cause COVID-19 and SARS-CoV-1 share 80% structural similarity, we present a comprehensive review of the diverse molecular inhibitors of SARS-CoV-1. This will help to accelerate drug discovery for deadly coronavirus diseases.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

A schematic representation of different methods to inhibit SARS-CoV-2 infection.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

The global outbreak of COVID-19 viral infection is associated with the absence of specific drug(s) for fighting this viral infection.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

Potential drug candidates derived from natural sources are posed for the development of anti-SARS CoV-2 therapeutics.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

Herpes Simplex Virus type 1 (HSV-1) is a nuclear replicating enveloped virus.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

Exploiting the power of nature to fight viral infections. This review describes the concept of direct- and host-acting natural products with broad-spectrum antiviral activities and provides promising examples derived from plants, fungi, bacteria and marine organisms.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

This review covers the increasing research efforts of the past decade, focusing on the structure, function and druggability of influenza NA, and its inhibition by natural products. Latest developments in theoretical and experimental research on NA for lead discovery strategies from nature are presented.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Point-of-care testing detection methods for COVID-19

This paper summarises the latest research advances and commercial products in POCT-based SARS-CoV-2 detection methods.

Graphical abstract: Point-of-care testing detection methods for COVID-19
Critical Review

A review of pharmaceutical occurrence and pathways in the aquatic environment in the context of a changing climate and the COVID-19 pandemic

Active pharmaceutical ingredients (APIs) are increasingly being identified as contaminants of emerging concern (CECs).

Graphical abstract: A review of pharmaceutical occurrence and pathways in the aquatic environment in the context of a changing climate and the COVID-19 pandemic
Open Access Critical Review

Current advances in the detection of COVID-19 and evaluation of the humoral response

SARS-CoV-2 and humoral response determinations to understand and control the spread of COVID-19.

Graphical abstract: Current advances in the detection of COVID-19 and evaluation of the humoral response
Open Access Critical Review

Detection of RNA viruses from influenza and HIV to Ebola and SARS-CoV-2: a review

RNA-based viruses likely make up the highest pandemic threat among all known pathogens in about the last 100 years, since the Spanish Flu of 1918 with 50 M deaths up to COVID-19.

Graphical abstract: Detection of RNA viruses from influenza and HIV to Ebola and SARS-CoV-2: a review
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

This review provides a comprehensive look at whether a pandemic enveloped virus would pose challenges for the wastewater and drinking water industries.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

An ideal approach to real-time disease detection and surveillance.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Colorimetric loop-mediated isothermal amplification (LAMP) for cost-effective and quantitative detection of SARS-CoV-2: the change in color in LAMP-based assays quantitatively correlates with viral copy number

Colorimetric LAMP for COVID-19 intensified diagnostics: a simple and quantitative method comparable in diagnostic performance to RT-qPCR.

Graphical abstract: Colorimetric loop-mediated isothermal amplification (LAMP) for cost-effective and quantitative detection of SARS-CoV-2: the change in color in LAMP-based assays quantitatively correlates with viral copy number
Communication

High-throughput wastewater analysis for substance use assessment in central New York during the COVID-19 pandemic

Wastewater analysis provides insights into population lifestyle and health status during the coronavirus pandemic.

Graphical abstract: High-throughput wastewater analysis for substance use assessment in central New York during the COVID-19 pandemic
Communication

Inhibitory activities of marine sulfated polysaccharides against SARS-CoV-2

Sulfated polysaccharide from sea cucumber (SCSP), fucoidan from brown algae, and iota-carrageenan from red algae show inhibitory activities against SARS-CoV-2.

Graphical abstract: Inhibitory activities of marine sulfated polysaccharides against SARS-CoV-2
Communication

Paper spray mass spectrometry utilizing Teslin® substrate for rapid detection of lipid metabolite changes during COVID-19 infection

Development of an identification methodology with PS-MS as a sensitive and rapid technique to obtain vastly different chemical changes in COVID-19 infection.

Graphical abstract: Paper spray mass spectrometry utilizing Teslin® substrate for rapid detection of lipid metabolite changes during COVID-19 infection
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

Unveiling the nanomechanical stability of the novel coronavirus (SARS-CoV-2) spike protein

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

Using a combination of enhanced sampling molecular dynamics techniques and non-equilibrium alchemical transformations, we have shown that hydroxychloroquine may act as a mild inhibitor of important functional proteins for SARS-CoV2 replication.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

The continued emergence and spread of infectious agents is of great concern, and systems biology approaches to infectious disease research can advance our understanding of host–pathogen relationships and facilitate the development of new therapies and vaccines.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

Multicolor silver nanoparticles enable multiplexed detection of dengue, yellow fever, and Ebola virus proteins in a single lateral flow strip.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

The SARS-CoV NTPase/helicase being able to unwind both RNA and DNA duplexes, is an attractive target for anti-viral drug design. A series of bismuth complexes were synthesized and characterized, and exhibit the inhibition against the SARS helicase ATPase and duplex-unwinding activities at micromolar concentrations.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

A versatile aptamer-assisted proximity ligation system improves diagnosis of COVID-19, and allows the evaluation of potential neutralizing aptamers.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

By integrating algebraic topology and deep learning, we provide a reliable ranking of binding affinities, binding site analysis, and fragment decomposition for 137 SARS-CoV-2 main protease inhibitors.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

A computer program for retrosynthetic planning helps develop multiple “synthetic contingency” plans for hydroxychloroquine and also routes leading to remdesivir, both promising but yet unproven medications against COVID-19.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

Herein we present a workflow for design and synthesis of novel selective Ub-based tools for DUBs. Selectivity is achieved by incorporation of unnatural amino acids into the Ub C-terminal epitope.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Open Access Paper

Non-woven materials for cloth-based face masks inserts: relationship between material properties and sub-micron aerosol filtration

Sub-micron aerosol filtration of non-woven materials and fabric treatments were investigated. Select low-cost, readily available and easily cut non-woven materials were identified as suitable filter inserts for cloth-based masks.

Graphical abstract: Non-woven materials for cloth-based face masks inserts: relationship between material properties and sub-micron aerosol filtration
Paper

Electrostatic interactions between the SARS-CoV-2 virus and a charged electret fibre

Electrostatic interactions between the surface of a single charged electret fibre and a model of the SARS-CoV-2 virus are drastically influenced by pH, salt concentration, and the charge on the fibre.

Graphical abstract: Electrostatic interactions between the SARS-CoV-2 virus and a charged electret fibre
Open Access Paper

The inhibition of Mpro, the primary protease of COVID-19, by Poria cocos and its active compounds: a network pharmacology and molecular docking study

The inhibition of Mpro, the primary protease of COVID-19, by Poria cocos.

Graphical abstract: The inhibition of Mpro, the primary protease of COVID-19, by Poria cocos and its active compounds: a network pharmacology and molecular docking study
Open Access Paper

A phytochemical-based medication search for the SARS-CoV-2 infection by molecular docking models towards spike glycoproteins and main proteases

Identifying best bioactive phytochemicals from different medicinal plants using molecular docking techniques demonstrates a potential pre-clinical compound discovery against SARS-CoV-2 viral infection.

Graphical abstract: A phytochemical-based medication search for the SARS-CoV-2 infection by molecular docking models towards spike glycoproteins and main proteases
Open Access Paper

The rapid diagnosis and effective inhibition of coronavirus using spike antibody attached gold nanoparticles

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of the coronavirus disease that began in 2019 (COVID-19), has been responsible for 1.4 million deaths worldwide as of 13 November 2020.

Graphical abstract: The rapid diagnosis and effective inhibition of coronavirus using spike antibody attached gold nanoparticles
Open Access Paper

Reproducibility and sensitivity of 36 methods to quantify the SARS-CoV-2 genetic signal in raw wastewater: findings from an interlaboratory methods evaluation in the U.S.

The reproducibility and sensitivity of 36 methods for quantifying the genetic signal of SARS-CoV-2 in wastewater was evaluated in a nationwide interlaboratory assessment in the U.S.

Graphical abstract: Reproducibility and sensitivity of 36 methods to quantify the SARS-CoV-2 genetic signal in raw wastewater: findings from an interlaboratory methods evaluation in the U.S.
Paper

Thin-film-transistor digital microfluidics for high value in vitro diagnostics at the point of need

The latest developments in thin-film-transistor digital-microfluidics (TFT-DMF) are reported, and proof of concept application to molecular diagnostics (e.g. for coronavirus disease, COVID-19) at the point-of-need demonstrated.

Graphical abstract: Thin-film-transistor digital microfluidics for high value in vitro diagnostics at the point of need
Paper

Rapid molecular diagnostics of COVID-19 by RT-LAMP in a centrifugal polystyrene-toner based microdevice with end-point visual detection

We developed a low-cost molecular test for the diagnosis of COVID-19, in a centrifugal microdevice, based on RT-LAMP assay run at 72 °C for 10 min.

Graphical abstract: Rapid molecular diagnostics of COVID-19 by RT-LAMP in a centrifugal polystyrene-toner based microdevice with end-point visual detection
Open Access Paper

Carbon nanotubes for rapid capturing of SARS-COV-2 virus: revealing a mechanistic aspect of binding based on computational studies

Investigation of the binding interactions of synthesized multi-walled carbon nanotubes (MWCNTs) with SARS-CoV-2 virus.

Graphical abstract: Carbon nanotubes for rapid capturing of SARS-COV-2 virus: revealing a mechanistic aspect of binding based on computational studies
Open Access Paper

Combination of system biology to probe the anti-viral activity of andrographolide and its derivative against COVID-19

The present study aimed to investigate the binding affinity of andrographolide and its derivative i.e. 14-deoxy-11,12-didehydroandrographolide with targets related to COVID-19 and their probable role in regulating multiple pathways in COVID-19 infection.

Graphical abstract: Combination of system biology to probe the anti-viral activity of andrographolide and its derivative against COVID-19
Paper

A digital protein microarray for COVID-19 cytokine storm monitoring

A digital microfluidic immunoassay platform enables rapid multiplex quantification of proinflammatory cytokines in serum for critically ill COVID-19 patients.

Graphical abstract: A digital protein microarray for COVID-19 cytokine storm monitoring
Paper

Colorimetric reverse transcription loop-mediated isothermal amplification (RT-LAMP) as a visual diagnostic platform for the detection of the emerging coronavirus SARS-CoV-2

RT-LAMP to detect SARS-CoV-2: in a positive sample, RT-LAMP leads to a color change from pink to yellow.

Graphical abstract: Colorimetric reverse transcription loop-mediated isothermal amplification (RT-LAMP) as a visual diagnostic platform for the detection of the emerging coronavirus SARS-CoV-2
Open Access Paper

Ligand-based design, molecular dynamics and ADMET studies of suggested SARS-CoV-2 Mpro inhibitors

Compounds I–X were designed to inhibit SARS-CoV-2 Mpro based on pharmacophore modeling of SARS-CoV Mpro inhibitors. Compounds V and VI showed promising molecular docking and molecular dynamic simulation results that surpassed baicalein.

Graphical abstract: Ligand-based design, molecular dynamics and ADMET studies of suggested SARS-CoV-2 Mpro inhibitors
Open Access Paper

In silico design of peptides with binding to the receptor binding domain (RBD) of the SARS-CoV-2 and their utility in bio-sensor development for SARS-CoV-2 detection

The protocol for peptide design and testing for its usage as a sensor.

Graphical abstract: In silico design of peptides with binding to the receptor binding domain (RBD) of the SARS-CoV-2 and their utility in bio-sensor development for SARS-CoV-2 detection
Open Access Paper

Interaction analyses of SARS-CoV-2 spike protein based on fragment molecular orbital calculations

Visualized IFIE results seen from chain-B of spike protein.

Graphical abstract: Interaction analyses of SARS-CoV-2 spike protein based on fragment molecular orbital calculations
Open Access Paper

Binding of inhibitors to the monomeric and dimeric SARS-CoV-2 Mpro

Binding of inhibitors to the monomeric SARS-CoV-2 Mpro is similar to the dimeric one.

Graphical abstract: Binding of inhibitors to the monomeric and dimeric SARS-CoV-2 Mpro
Open Access Paper

Inhibitory activity of quercetin, its metabolite, and standard antiviral drugs towards enzymes essential for SARS-CoV-2: the role of acid–base equilibria

Identification of potential inhibitory effect of acid–base species of quercetin and its metabolite as well as chloroquine, hydroxychloroquine, and cinanserin, at physiological pH, on proteins essential for SARS-CoV-2 virus survival.

Graphical abstract: Inhibitory activity of quercetin, its metabolite, and standard antiviral drugs towards enzymes essential for SARS-CoV-2: the role of acid–base equilibria
Paper

A high-throughput multiplexed microfluidic device for COVID-19 serology assays

A microfluidic device to quantitate antibody reactivities to SARS-CoV-2 antigens: spike protein, RDB, S1 subunit, and nucleocapsid, from 50 serum samples.

Graphical abstract: A high-throughput multiplexed microfluidic device for COVID-19 serology assays
Open Access Paper

Interpretation of SARS-CoV-2 behaviour on different substrates and denaturation of virions using ethanol: an atomic force microscopy study

We studied the density and aggregation behavior of virions on TCPS and glass substrates, surface functionality, coffee ring effect on both surfaces and the effect of ethanol-based disinfectant on the virion structure using atomic force microscopy.

Graphical abstract: Interpretation of SARS-CoV-2 behaviour on different substrates and denaturation of virions using ethanol: an atomic force microscopy study
Open Access Paper

In silico identification of SARS-CoV-2 spike (S) protein–ACE2 complex inhibitors from eight Tecoma species and cultivars analyzed by LC-MS

In silico exploration of 12 Tecoma phytocompounds that could serve as potential inhibitors of SARS-CoV entry to host cells.

Graphical abstract: In silico identification of SARS-CoV-2 spike (S) protein–ACE2 complex inhibitors from eight Tecoma species and cultivars analyzed by LC-MS
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

The polymer polyphosphate, abundant in blood platelets, blocks the binding of the receptor-binding domain (RBD) of the SARS- spike (S)-protein to the angiotensin-converting enzyme 2 (ACE2) at low concentrations.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Paper

Detection of the SARS-CoV-2 humanized antibody with paper-based ELISA

This work reports the development of a rapid, simple and inexpensive colorimetric paper-based assay for the detection of the severe acute respiratory symptom coronavirus 2 (SARS-CoV-2) humanized antibody.

Graphical abstract: Detection of the SARS-CoV-2 humanized antibody with paper-based ELISA
195 items - Showing page 1 of 3

About this collection

All Royal Society of Chemistry articles on coronavirus research can be found here and are freely available until 31st December 2021.

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