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Issue 45, 2005
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Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

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Abstract

Polyoxometalates (PMs) as discrete metal-oxide cluster anions comprise a versatile class of inorganic, anionic clusters that have a wide variety of structures, sizes, and a combination of metals, high solubility in water, and electrochemical activity. Recent investigation of anti-tumor, -viral, and -bacterial activities of PMs shows induced cell-apoptosis, inhibition of binding of virus to receptor, and the enhancement of β-lactam antibiotics as well as the inhibition of bacterial growth, respectively. PMs exemplified for each biological activity are discussed from the chemotherapeutic point of view for the establishment of a novel inorganic drug based on PMs.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

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Article information


Submitted
01 Apr 2005
Accepted
20 Jun 2005
First published
21 Jul 2005

J. Mater. Chem., 2005,15, 4773-4782
Article type
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

T. Yamase, J. Mater. Chem., 2005, 15, 4773
DOI: 10.1039/B504585A

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