Themed collection 2021 Reviews in RSC Advances
Application of Pauson–Khand reaction in the total synthesis of terpenes
The Pauson–Khand reaction (PKR) is a formal [2 + 2 + 1] cycloaddition involving an alkyne, an alkene and carbon monoxide mediated by a hexacarbonyldicobaltalkyne complex to yield cyclopentenones in a single step.
Reprogramming natural proteins using unnatural amino acids
Incorporation of unnatural amino acids into protein offers wide array of applications in fundamental and applied science.
Recent advances of N-heterocyclic carbenes in the applications of constructing carbo- and heterocyclic frameworks with potential biological activity
A general picture of utilization of NHCs in constructing several kinds of bioactive cyclic skeletons.
Recent applications of solid-phase strategy in total synthesis of antibiotics
The recent applications of solid-phase strategy in total synthesis of antibiotics were summarized, and the structure–activity relationship could be established to conquer the challenge of bacterial resistance preparedness.
Progress of low-frequency sound absorption research utilizing intelligent materials and acoustic metamaterials
In this review, the latest progress of intelligent materials incorporated with acoustic metamaterials is summarized to provide an impetus for this highly interdisciplinary advancement towards low-frequency sound absorption.
Bacterial virulence factors: a target for heterocyclic compounds to combat bacterial resistance
This review presents an overview of different heterocyclic compounds that act as anti-virulence agents in order to overcome microbial resistance.
Identifying the specific-targeted marine cerebrosides against SARS-CoV-2: an integrated computational approach
Cerebrosides are a group of metabolites belonging to the glycosphingolipids class of natural products.
Engineering encapsulated ionic liquids for next-generation applications
Encapsulated ionic liquids (ILs) are candidate materials for several applications owing to the attractive properties of ILs combined with the enhanced mass transfer rate obtained through the discretization of ILs in small capsules.
Additive manufacturing technology of polymeric materials for customized products: recent developments and future prospective
The worldwide demand for additive manufacturing (AM) is increasing due to its ability to produce more challenging customized objects based on the process parameters for engineering applications.
Recent advances in dye and metal ion removal using efficient adsorbents and novel nano-based materials: an overview
Various materials including waste precursors used as adsorbents for water treatment (dyes and metal ions removal).
Computational methods directed towards drug repurposing for COVID-19: advantages and limitations
Different kind of methods utilized in expediting drug repurposing.
Chemistry and biological activities of hetisine-type diterpenoid alkaloids
Natural hetisine-type C20-diterpenoid alkaloids with diverse structures showed multiple pharmacological activities, indicating great potential in drug discovery.
Journey of anthraquinones as anticancer agents – a systematic review of recent literature
Anthraquinones are privileged chemical motifs with diverse therapeutic applications, especially in the treatment of cancer. The extensive literature highlights the significance of anthraquinones as potent anticancer agents.
A review on phytochemical constituents and pharmacological potential of Calotropis procera
Calotropis procera is also known as Aak or Madar. The present review provides a systematic outline of phytochemistry, toxicology, pharmacology and therapeutic potential of Calotropis procera.
Membrane technologies in toilet urine treatment for toilet urine resource utilization: a review
In this review, the membrane technologies used for the resource utilization of urine collected from toilets are divided into four categories based on their driving force.
Recent advances in functionalized upconversion nanoparticles for light-activated tumor therapy
Light-activated tumor therapy (photodynamic therapy, gene therapy, immunotherapy, chemo-therapy and integrated therapy) based on UCNPs and the corresponding mechanisms.
Recent progresses in the synthesis of MnO2 nanowire and its application in environmental catalysis
This review summarizes the synthesis strategies for MnO2 nanowire and the influences of the phase structure, crystal facet, metal doping, and interface effect on its performance in various environmental catalysis processes.
Nanotechnology-based strategies for gastric cancer imaging and treatment
Nanoparticles designed for gastric cancer theronostics.
Do amino acid functionalization stratagems on carbonaceous quantum dots imply multiple applications? A comprehensive review
A schematic representation of amino acid-functionalized graphene quantum dots.
Anti-bacterial activity of gold nanocomposites as a new nanomaterial weapon to combat photogenic agents: recent advances and challenges
Gold nanocomposites are being widely used in numerous biomedical applications owing to their excellent stability and miniaturization.
Photoelectron photofragment coincidence spectroscopy of carboxylates
Photoelectron photofragment coincidence spectroscopy studies of a range of carboxylate anions are reviewed, revealing details of the decarboxylation dynamics of carboxyl radicals.
Chemosensors based on N-heterocyclic dyes: advances in sensing highly toxic ions such as CN− and Hg2+
This review considers the most recent advances in sensing highly toxic ions such as CN− and Hg2+. Specifically, probes bearing N-heterocyclic compounds for their proven versatility for applications in the development of chemosensors are analyzed.
Towards conductive hydrogels in e-skins: a review on rational design and recent developments
This review constructed a framework of methodologies to summarize the recent progress of high-performance conductive hydrogels for flexible electronics and further provide novel insights about rational design of the advanced hydrogels.
Synthesis of indole derivatives as prevalent moieties present in selected alkaloids
In this review, we aim to highlight the synthesis of indoles as a moiety in selected alkaloids.
Direct halosulfonylation of alkynes: an overview
The difunctionalizations of alkynes have emerged as a powerful, and step-economical approach for the construction of highly substituted alkenes in a one-pot manner, without the need for isolation of intermediates.
Long-term durability and ecotoxicity of biocomposites in marine environments: a review
Long term durability and moisture ingress effects on the mechanical property is highlighted where tensile strength is reduced as the moisture immersion time increases showing weak fibre matrix interfaces evidenced from SEM micrograph.
Scientific information about sugar-based emulsifiers: a comprehensive review
Amphiphilic natural emulsifiers form tiny droplets of oil-in-water stable emulsions and are very much effective for industries.
An overview of metal-free synthetic routes to isoxazoles: the privileged scaffold
Isoxazole, a five-membered heterocyclic moiety commonly found in many commercially available drugs. This review article presents a comprehensive overview on metal-free synthetic routes for the synthesis of isoxazoles with significant bioactivities.
Biomedical nanobubbles and opportunities for microfluidics
The use of bulk nanobubbles in biomedicine is increasing in recent years. This translates into new opportunities for microfluidics, which may enable the generation of higher quality nanobubbles that lead to advances in diagnostics and therapeutics.
Alkoxysulfenylation of alkenes: development and recent advances
The vicinal difunctionalization of carbon–carbon double bonds represents one of the most powerful and effective strategies in a one-pot process.
Direct synthesis of sulfenamides, sulfinamides, and sulfonamides from thiols and amines
This review provides a concise overview of the synthesis of biologically and synthetically valuable sulfenamide, sulfinamide, and sulfonamide derivatives through the direct oxidative coupling of readily available low-cost thiols and amines.
Recent progress in the use of diaziridine-based sweetener derivatives to elucidate the chemoreception mechanism of the sweet taste receptor
The review summarized recent progress for the elucidation of the chemoreception mechanism of sweet taste receptor–sweetener interactions with photoaffinity labeling.
Scholl reaction as a powerful tool for the synthesis of nanographenes: a systematic review
Nanographenes have been attracting increasing attention owing to their widespread applications in organic electronics. Polycyclic aromatic hydrocarbons are popular research subjects due to their high stability, planar structure and optical spectra.
On the diatomite-based nanostructure-preserving material synthesis for energy applications
The present article overviews the current state-of-the-art and future prospects for the use of diatomaceous earth (DE) in the continuously expanding sector of energy science and technology.
Methods of hexagonal boron nitride exfoliation and its functionalization: covalent and non-covalent approaches
Synthesis methods for the exfoliation of BNNSs and BNNS functionalization methods are reviewed.
A review on the phytochemistry and pharmacology of the herb Scoparia dulcis L. for the potential treatment of metabolic syndrome
This review discusses the chemical constituents and pharmacological effects of S. dulcis plants. S. dulcis provides new potential for medicine and can be promoted as a complementary or alternative therapy for patients with chronic conditions.
Expanding the PET radioisotope universe utilizing solid targets on small medical cyclotrons
The production of novel radioisotopes on small-to-medium cyclotrons equipped with solid targets will be vital to meet the demand of theragnostics research.
Fly ash-, foundry sand-, clay-, and pumice-based metal oxide nanocomposites as green photocatalysts
This review highlights recent advances in the utilization of natural materials (clay mineral and pumice)- and waste materials (ash and foundry sand)-based metal oxide nanocomposites for photodegradation of various pollutants.
Cyclodextrins: promising scaffolds for MRI contrast agents
This review highlights that supramolecular associations using host–guest inclusion complexation and covalent linkages can improve the image contrast, the sensitivity, and the efficiency of MRI diagnosis.
The recent development of donepezil structure-based hybrids as potential multifunctional anti-Alzheimer's agents: highlights from 2010 to 2020
This review highlights recent examples of multi-target-directed ligands (MTDLs) based on donepezil structure modification from 2010 onwards.
The intrinsic piezoelectric properties of materials – a review with a focus on biological materials
Piezoelectricity, a linear electromechanical coupling, is of great interest due to its extensive applications including energy harvesters, biomedical, sensors, and automobiles.
The development of biomass-derived carbon-based photocatalysts for the visible-light-driven photodegradation of pollutants: a comprehensive review
This review highlights recent advances relating to the synthesis of biomass-derived carbon-based photocatalysts in light of their potential use in the photodegradation of various pollutants.
The exposome paradigm to predict environmental health in terms of systemic homeostasis and resource balance based on NMR data science
From the environmental samples, such as waters, soils, as well as microbiome and biome, NMR data science can evaluate the exposome, namely the totality of exposure to physical/chemical/biological factors from natural environment and human society
Layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications
In this review, we study potential applications of LDHs for tissue engineering and discuss some recent studies on biocompatibility, antibacterial and osteogenic differentiation behaviors of LDHs.
DDQ as a versatile and easily recyclable oxidant: a systematic review
DDQ is the most widely used quinone with a high reduction potential and it mediates hydride transfer reactions and shows three accessible oxidation states: quinone (oxidized), semiquinone (one-electron-reduced) and hydroquinone (two-electron-reduced).
Recent progress in cadmium fluorescent and colorimetric probes
Cadmium is a heavy metal which exists widely in industrial and agricultural production and can induce a variety of diseases in organisms.
Recent developments in the kinetics of ruptures of giant vesicles under constant tension
The kinetics of ruptures of giant vesicles under constant tension have been investigated under various conditions, which will help in the application of these techniques in the biomedical, bioengineering, and biotechnological fields.
Recent developments of a co-immobilized laccase–mediator system: a review
The laccase–mediator is a promising biocatalyst with many possible applications, including bioremediation, chemical synthesis, biobleaching of paper pulp, biosensing, textile finishing and wine stabilization.
CDK4/6 inhibitors: a brief overview and prospective research directions
The discovery of cyclin-dependent kinases (CDK) and their mechanism in regulating the cell cycle process was considered a game-changer in cancer therapy.
Lipid-based nanoparticles for psoriasis treatment: a review on conventional treatments, recent works, and future prospects
Lipid-based nanoparticles are lipidic nanocarriers that can encapsulate different antipsoriatic agents for topical uses, which enhance the alleviation process compared to conventional topical agents (without nanocarriers).
A review on convenient synthesis of substituted coumarins using reuseable solid acid catalysts
Due to growing concern about chemicals and their impact on the environment, cleaner reaction conditions are needed to be incorporated into chemical synthetic procedures.
Metal–organic framework based electrode materials for lithium-ion batteries: a review
In this review article, a comprehensive insight is given into current progress of electrochemical evaluation of MOFs based material as efficient anode and cathode materials for LIBs.
Overview on magnetically recyclable ferrite nanoparticles: synthesis and their applications in coupling and multicomponent reactions
Applications of ferrite nanoparticles in various chemical transformations.
Recent advances in biological nanopores for nanopore sequencing, sensing and comparison of functional variations in MspA mutants
Future of nanopore DNA sequencing: schematic illustration shows the future of nanopore DNA sequencing by using a customized biological nanopore with appropriate fabrication.
3-Hydroxyflavone derivatives: promising scaffolds for fluorescent imaging in cells
Considering that biological macromolecules offer hydrophobic microenvironment, 3HF is a promising scaffold for the development of fluorescent imaging in cells.
A review of shape memory polymers based on the intrinsic structures of their responsive switches
Responsive switches classification by their intrinsic structures: physical switch and chemical one.
Traditional uses, phytochemistry, pharmacology, and toxicology of Pterocephalus hookeri (C. B. Clarke) Höeck: a review
Pterocephalus hookeri (C. B. Clarke) Höeck has been used in traditional Tibetan medicine for thousands of years. The existing research results of P. hookeri are summarized, and will provide a basis for the further development of new drugs.
A minireview on the perturbation effects of polar groups to direct nanoscale hydrophobic interaction and amphiphilic peptide assembly
Hydrophobic interaction provides the essential driving force for creating diverse native and artificial supramolecular architectures.
DNA interfaces with dimensional materials for biomedical applications
DNA interfaces with 0–3 dimensional materials through physisorption and chemisorption mechanisms acquire unique interfacial character for novel biomedical applications.
The role of biocatalysis in the asymmetric synthesis of alkaloids – an update
This review article discusses developments in the chemo-enzymatic synthesis of alkaloids since 2013, showcasing how modern methods of organic synthesis and biocatalysis are combined to establish novel routes towards these important natural products.
Advances in biopolymeric active films incorporated with emulsified lipophilic compounds: a review
The attention towards active films has increased due to consumer demand for high-quality foods without chemical additives.
Reducing the resistance for the use of electrochemical impedance spectroscopy analysis in materials chemistry
This manuscript highlights a beginner-to-intermediate level scope of electrochemical impedance spectroscopy (EIS), which is an indispensable, non-destructive electrochemical technique that can be applied for materials characterization.
Target identification of anticancer natural products using a chemical proteomics approach
Natural products are one of the most effective therapeutic candidates in cancer treatment. In this review, we briefly discuss the target identification of anticancer natural products in different cancer cell lines through a chemical proteomics approach.
A review on the use of DFT for the prediction of the properties of nanomaterials
Depiction of unusual properties of nanomaterials through DFT studies.
Synthesis of holey graphene for advanced nanotechnological applications
The review paper presents a systematic understanding of different synthesis routes to obtain holey graphene, its properties, and key applications in different fields. The article also evaluates the current progress and future opportunities of HG.
A review: the botany, ethnopharmacology, phytochemistry, pharmacology of Cinnamomi cortex
Cinnamomi Cortex (CC) is the dried bark of Cinnamomum cassia (L.) J. Presl.
Recent progress of biomimetic motions—from microscopic micro/nanomotors to macroscopic actuators and soft robotics
Biomimetic motions are derived from the many different functional materials and/or intricate and highly organized structure of the biological material from the molecular to the nanoscale, microscale and macroscale.
Recent advances in the conversion of furfural into bio-chemicals through chemo- and bio-catalysis
Furfural is a promising renewable platform molecule derived from hemi-cellulose, which can be further converted to fossil fuel alternatives and valuable chemicals due to its highly functionalized molecular structure.
Recent advances in bismuth oxyhalide photocatalysts for degradation of organic pollutants in wastewater
Advances in BiOX photocatalysts for degradation of organic pollutants are introduced, including the controllable synthesis, heteroatom doping & surface modification, BiOX/BiOY and BiOX/BimOnXz heterojunctions.
Medicinal chemistry inspired by ginger: exploring the chemical space around 6-gingerol
Structure and reported bioactivities of semi-synthetic and synthetic 6-gingerol derivatives.
About this collection
This web collection brings together all of the reviews published in RSC Advances in 2021.