Themed collection In celebration of Chinese New Year
Tuning the stability of organic radicals: from covalent approaches to non-covalent approaches
Covalent and non-covalent approaches to tune the stability of organic radicals through steric effects and the delocalization of spin density.
Activatable molecular agents for cancer theranostics
Activatable molecualr agents that intergrate diagnosis and treatment modalities have attracted great attention due to its abilities of personalized therapy and real-time monitoring of therapeutic outcome.
Fluorescent probes for organelle-targeted bioactive species imaging
The dynamic fluctuations of bioactive species in living cells are associated with numerous physiological and pathological phenomena. The emergence of organelle-targeted fluorescent probes has significantly facilitated our understanding on the biological functions of these species. This review describes the design, applications, challenges and potential directions of organelle-targeted bioactive species probes.
Recent advances in photoredox and nickel dual-catalyzed cascade reactions: pushing the boundaries of complexity
Cascade reactions that produce multiple chemical bonds in one synthetic operation are important in the efficient construction of complex molecules.
Improving MOF stability: approaches and applications
This review summarizes recent advances in the design and synthesis of stable MOFs and highlights the relationships between the stability and functional applications.
Zinc–air batteries: are they ready for prime time?
Zn–air batteries are under revival.
Intramolecular Csp3–H/C–C bond amination of alkyl azides for the selective synthesis of cyclic imines and tertiary amines
A novel intramolecular cyclization of alkyl azides for the synthesis of cyclic imines and tertiary amines has been developed. The aliphatic C–H or C–C bond was selectively cleaved with the efficient formation of two C–N single bonds or a CN double bond.
Type I photosensitizers based on phosphindole oxide for photodynamic therapy: apoptosis and autophagy induced by endoplasmic reticulum stress
Phosphindole oxide-based photosensitizers with Type I reactive oxygen species generation ability are developed and used for endoplasmic reticulum stress-mediated photodynamic therapy of tumors.
Regiodivergent construction of medium-sized heterocycles from vinylethylene carbonates and allylidenemalononitriles
Here we report palladium-catalyzed, regiodivergent [5 + 4] and [5 + 2] annulations of vinylethylene carbonates and allylidenemalononitriles affording over 50 medium-sized heterocycles in high isolated yields with excellent regioselectivities.
Novel NIR-II organic fluorophores for bioimaging beyond 1550 nm
Novel NIR-II organic fluorophores were designed and synthesized using an AIE and highly twisted donor–acceptor distortion strategy for bio-imaging beyond 1550 nm.
Target identification among known drugs by deep learning from heterogeneous networks
Target identification and drug repurposing could benefit from network-based, rational deep learning prediction, and explore the relationship between drugs and targets in the heterogeneous drug–gene–disease network.
A H2O2 self-sufficient nanoplatform with domino effects for thermal-responsive enhanced chemodynamic therapy
Phase change material based H2O2 self-supply nanoparticles for enhanced thermal responsive chemodynamic tumor therapy.
Breaking scaling relations for efficient CO2 electrochemical reduction through dual-atom catalysts
Monolayer C2N supported heteronuclear dual-atom catalysts are designed for efficient CO2 electrochemical reduction.
Rational synthesis of interpenetrated 3D covalent organic frameworks for asymmetric photocatalysis
Covalent organic frameworks (COFs) show great promise as heterogeneous photocatalysts, but they have not yet been explored for asymmetric photocatalysis, which is important for the sustainable production of pharmaceuticals and fine chemicals.
Formyl-selective deuteration of aldehydes with D2O via synergistic organic and photoredox catalysis
Formyl-selective deuteration of aldehydes with D2O mediated by the synergistic combination of light-driven, polyoxometalate-facilitated HAT and thiol catalysis is reported.
Regioselective electrosynthesis of tetra- and hexa-functionalized fullerene derivatives with unprecedented addition patterns
The regioselective electrosynthesis of tetra- and hexa-functionalized fullerene derivatives with unprecedented 1,2,4,17-(cis-3′) and 1,2,3,4,9,10-(“S”-shaped) addition patterns is achieved.
Bidirectional enantioselective synthesis of bis-benzofuran atropisomeric oligoarenes featuring two distal C–C stereogenic axes
We report the bidirectional enantioselective synthesis of bis-benzofuran atropisomeric oligoarenes featuring two distal C–C stereogenic axes. These are controlled by a two-fold central-to-axial chirality conversion upon oxidative aromatization.
Synthesis of amino acids and peptides with bulky side chains via ligand-enabled carboxylate-directed γ-C(sp3)–H arylation
Pd-catalyzed ligand-enabled γ-C(sp3)–H arylation of tert-leucine and its derived peptides without using an external directing group via a less favored six-membered palladacycle is reported.
Light-triggered nitric oxide (NO) release from photoresponsive polymersomes for corneal wound healing
Nitric oxide-releasing amphiphiles are successfully synthesized through direct polymerization and are engineered as photoresponsive polymersomes for biomedical applications.
A structure–property study of fluoranthene-cored hole-transporting materials enables 19.3% efficiency in dopant-free perovskite solar cells
A systematic structure–property correlation study was conducted to preliminarily elucidate an inherent regularity governing the structure of dopant-free HTMs.
Boosting the circularly polarized luminescence of small organic molecules via multi-dimensional morphology control
By regulating the composition of solvents, the assembled nanostructures of chiral molecules transformed from 0D nanospheres to 3D nanoflakes, which showed significantly amplified circularly polarized luminescence.
Crystallographic characterization of Y2C2n (2n = 82, 88–94): direct Y–Y bonding and cage-dependent cluster evolution
The long-sought Y–Y bonding is experimentally observed in organometallic complexes for the first time by encapsulation inside the hollow cavity of C3v(8)-C82 and Cs(6)-C82 fullerene cages.
Pore-tuning to boost the electrocatalytic activity of polymeric micelle-templated mesoporous Pd nanoparticles
Understanding how mesoporous noble metal architectures affect electrocatalytic performance is very important for the rational design and preparation of high-performance electrocatalysts.
Mitochondrion-targeted platinum complexes suppressing lung cancer through multiple pathways involving energy metabolism
Monofunctional platinum complexes restrain lung cancer through disrupting mitochondrial oxidative phosphorylation and glycolysis in addition to damaging nuclear and mitochondrial DNA.
Through-space charge transfer hexaarylbenzene dendrimers with thermally activated delayed fluorescence and aggregation-induced emission for efficient solution-processed OLEDs
Through-space charge transfer hexaarylbenzene dendrimers containing circularly-arrayed electron donors and acceptors exhibit thermally activated delayed fluorescence and aggregation-induced emission effects, giving EQE of 14.2% for solution-processed OLEDs.
A generalizable method for the construction of MOF@polymer functional composites through surface-initiated atom transfer radical polymerization
A universal method to grow polymers on MOF surfaces with well-defined thickness, sequence and functionality.
An enzyme-free molecular catalytic device: dynamically self-assembled DNA dendrimers for in situ imaging of microRNAs in live cells
Branched catalytic hairpin assembly is proposed for dynamic self-assembly of DNA dendrimers for signal amplification and in situ imaging of microRNAs in live cells with high sensitivity and selectivity.
Visible-light-mediated Minisci C–H alkylation of heteroarenes with unactivated alkyl halides using O2 as an oxidant
Herein, we report a protocol for direct visible-light-mediated Minisci C–H alkylation of heteroarenes with unactivated alkyl halides using molecular oxygen as an oxidant at room temperature.
Chemical and photochemical DNA “gears” reversibly control stiffness, shape-memory, self-healing and controlled release properties of polyacrylamide hydrogels
Stimuli-responsive polyacrylamide hydrogels crosslinked by glucosamine–boronate/G-quadruplexes or azobenzene-functionalized DNA reveal controlled stiffness using chemical or photochemical triggers.
Nickel-catalyzed allylic defluorinative alkylation of trifluoromethyl alkenes with reductive decarboxylation of redox-active esters
Synthesis of functionalized gem-difluoroalkenes was achieved through nickel-catalyzed allylic defluorinative alkylation of trifluoromethyl alkenes with reductive decarboxylation of redox-active esters.
A lithium-ion-active aerolysin nanopore for effectively trapping long single-stranded DNA
By developing lithium-ion-active aerolysin, for the first time we have achieved aerolysin detection of single-stranded DNA longer than 100 nt.
Unusual fcc-structured Ag10 kernels trapped in Ag70 nanoclusters
A bioctahedral Ag10 kernel is locked by a pair of Mo7O2610− anions to form an inner Ag10@(Mo7O26)2 core which is further encapsulated by an outer Ag70 shell to form three-shell Ag10@(Mo7O26)2@Ag70 nanoclusters.
Identification of Pt-based catalysts for propane dehydrogenation via a probability analysis
A probability-based computational screening study has successfully identified an optimal bimetallic alloy (Pt3In) for the propane dehydrogenation reaction.
About this collection
In celebration of Chinese New Year, we are delighted to present a special collection of articles by authors in China. This collection of recent popular articles highlights important contributions from China in a range of fields including analytical science, bioinorganic, catalysis, chemical biology, environmental and sustainable chemistry, materials science, organic chemistry, physical chemistry and supramolecular chemistry.
We would like to wish everyone a Happy Chinese New Year!