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Themed collection Biomaterials Science Emerging Investigators

23 items
Editorial

Biomaterials Science Emerging Investigators 2019

This themed issue of Biomaterials Science highlights the work of emerging investigators in the field of biomaterials science. Editor-in-Chief Jennifer Elisseeff introduces the issue.

Graphical abstract: Biomaterials Science Emerging Investigators 2019
From the themed collection: Biomaterials Science Emerging Investigators
Minireview

Printed nanofilms mechanically conforming to living bodies

Printed nanofilms consisting of ultra-flexible polymer nanosheets and various inks mechanically conform to the living body and provide a range of biomedical applications.

Graphical abstract: Printed nanofilms mechanically conforming to living bodies
From the themed collection: Biomaterials Science Emerging Investigators
Minireview

Tunable biomaterials from synthetic, sequence-controlled polymers

This mini-review discusses progress in the synthesis of sequence-controlled polymers and highlights recent studies demonstrating sequence effects on biomaterial properties.

Graphical abstract: Tunable biomaterials from synthetic, sequence-controlled polymers
From the themed collection: Biomaterials Science Emerging Investigators
Minireview

Acellular biomaterial strategies for endodontic regeneration

This review highlights the evolution of regenerative dental materials with a focus on acellular biomaterials for endodontic treatment.

Graphical abstract: Acellular biomaterial strategies for endodontic regeneration
From the themed collection: Biomaterials Science Emerging Investigators
Minireview

Engineering a stable future for DNA-origami as a biomaterial

Reviewing the various methods and effectivity to stabilize DNA origami in biological environments.

Graphical abstract: Engineering a stable future for DNA-origami as a biomaterial
From the themed collection: Biomaterials Science Emerging Investigators
Minireview

Controlled synthesis and assembly of ultra-small nanoclusters for biomedical applications

This Minireview summarizes recent advances in the controlled synthesis, assembly, and biomedical applications of ultra-small nanoclusters.

Graphical abstract: Controlled synthesis and assembly of ultra-small nanoclusters for biomedical applications
From the themed collection: Biomaterials Science Emerging Investigators
Minireview

Nanomaterials for photoacoustic imaging in the second near-infrared window

The use of nanomaterials as contrast agents for photoacoustic imaging in the NIR-II window enables enhanced imaging quality with deeper tissue penetration.

Graphical abstract: Nanomaterials for photoacoustic imaging in the second near-infrared window
From the themed collection: Biomaterials Science Emerging Investigators
Review Article

Peptide ligand-mediated targeted drug delivery of nanomedicines

Targeted drug delivery is emerging as a promising strategy to achieve better clinical outcomes.

Graphical abstract: Peptide ligand-mediated targeted drug delivery of nanomedicines
From the themed collection: Biomaterials Science Emerging Investigators
Communication

Logical stimuli-triggered delivery of small molecules from hydrogel biomaterials

Triggered release of small molecule model therapeutics from hydrogel biomaterials is governed by user-programmable Boolean logic.

Graphical abstract: Logical stimuli-triggered delivery of small molecules from hydrogel biomaterials
From the themed collection: Biomaterials Science Emerging Investigators
Accepted Manuscript - Paper

Conductive elastomer composites for fully polymeric, flexible bioelectronics

From the themed collection: Biomaterials Science Emerging Investigators
Paper

Universal nanothin silk coatings via controlled spidroin self-assembly

Biomimetic spidroin self-assembly allows formation of substrate-independent one-pot nanothin silk coatings.

Graphical abstract: Universal nanothin silk coatings via controlled spidroin self-assembly
From the themed collection: Biomaterials Science Emerging Investigators
Paper

Platelet-like particles dynamically stiffen fibrin matrices and improve wound healing outcomes

PLPs increase fibrin stiffness, promote cell migration, and improve healing outcomes.

Graphical abstract: Platelet-like particles dynamically stiffen fibrin matrices and improve wound healing outcomes
From the themed collection: Biomaterials Science Emerging Investigators
Paper

Adipose-derived stem cell-secreted factors promote early stage follicle development in a biomimetic matrix

ADSCs encapsulated in biomimetic PEG hydrogels maintain stemness and secrete survival- and growth-promoting factors that support in vitro folliculogenesis.

Graphical abstract: Adipose-derived stem cell-secreted factors promote early stage follicle development in a biomimetic matrix
From the themed collection: Biomaterials Science Emerging Investigators
Paper

Celastrol-loaded PEG-b-PPS nanocarriers as an anti-inflammatory treatment for atherosclerosis

Encapsulation within poly(ethylene glycol)-b-poly(propylene sulfide) micelles reduces the toxicity of celastrol and enhances its anti-inflammatory effect during treatment of atherosclerosis.

Graphical abstract: Celastrol-loaded PEG-b-PPS nanocarriers as an anti-inflammatory treatment for atherosclerosis
From the themed collection: Biomaterials Science Emerging Investigators
Paper

Characterizing the encapsulation and release of lentivectors and adeno-associated vectors from degradable alginate hydrogels

In this study, we compare the ability of two different degradable alginate hydrogel formulations to efficiently deliver LV and AAV. We propose that release rates of viral vectors are dependent on the physical properties of both the hydrogels and vectors.

Graphical abstract: Characterizing the encapsulation and release of lentivectors and adeno-associated vectors from degradable alginate hydrogels
From the themed collection: Biomaterials Science Emerging Investigators
Paper

Fabrication of redox-responsive doxorubicin and paclitaxel prodrug nanoparticles with microfluidics for selective cancer therapy

Doxorubicin–paclitaxel prodrug nanoparticles with redox-responsive were synthesized to selectively inhibit cancer cells with reduced adverse drug effect to healthy cells.

Graphical abstract: Fabrication of redox-responsive doxorubicin and paclitaxel prodrug nanoparticles with microfluidics for selective cancer therapy
From the themed collection: Biomaterials Science Emerging Investigators
Paper

Polyester-based ink platform with tunable bioactivity for 3D printing of tissue engineering scaffolds

A novel polymeric biomaterial platform with tunable functionalizability for extrusion-based 3D printing.

Graphical abstract: Polyester-based ink platform with tunable bioactivity for 3D printing of tissue engineering scaffolds
From the themed collection: Biomaterials Science Emerging Investigators
Paper

Macromolecular crowding tunes 3D collagen architecture and cell morphogenesis

Macromolecular crowding of collagen I during polymerization produces short, degradation-resistant fibrils that induce collective morphogenesis of breast cancer cells.

Graphical abstract: Macromolecular crowding tunes 3D collagen architecture and cell morphogenesis
From the themed collection: Biomaterials Science Emerging Investigators
Paper

Degradable redox-responsive disulfide-based nanogel drug carriers via dithiol oxidation polymerization

Stimuli-responsive nanogels degrade to small molecules in reducing environments to mediate controlled drug release.

Graphical abstract: Degradable redox-responsive disulfide-based nanogel drug carriers via dithiol oxidation polymerization
From the themed collection: Biomaterials Science Emerging Investigators
Paper

A pH-responsive hydrogel with potent antibacterial activity against both aerobic and anaerobic pathogens

A pH-responsive hydrogel prepared by oxidized dextran with aminoglycoside and an ornidazole analogue can kill both aerobic and anaerobic pathogens.

Graphical abstract: A pH-responsive hydrogel with potent antibacterial activity against both aerobic and anaerobic pathogens
From the themed collection: Biomaterials Science Emerging Investigators
Paper

The influence of electrically conductive and non-conductive nanocomposite scaffolds on the maturation and excitability of engineered cardiac tissues

We developed different classes of hydrogels, with conductive and non-conductive nanomaterials, to study cardiac tissue maturation and excitability.

Graphical abstract: The influence of electrically conductive and non-conductive nanocomposite scaffolds on the maturation and excitability of engineered cardiac tissues
From the themed collection: Biomaterials Science Emerging Investigators
Paper

Delivery of 5′-triphosphate RNA with endosomolytic nanoparticles potently activates RIG-I to improve cancer immunotherapy

Delivery of a 5′ triphosphate RNA (3pRNA), a ligand for RIG-I, with endosomolytic nanoparticles (NP) augments response to anti-PD1 immune checkpoint blockade.

Graphical abstract: Delivery of 5′-triphosphate RNA with endosomolytic nanoparticles potently activates RIG-I to improve cancer immunotherapy
From the themed collection: Biomaterials Science Emerging Investigators
Paper

Intracellular delivery and biodistribution study of CRISPR/Cas9 ribonucleoprotein loaded bioreducible lipidoid nanoparticles

A combinatorial library of cationic lipidoids were used as nanocarriers for intracellular delivery of the CRISPR/Cas9 ribonucleoprotein complex.

Graphical abstract: Intracellular delivery and biodistribution study of CRISPR/Cas9 ribonucleoprotein loaded bioreducible lipidoid nanoparticles
From the themed collection: Biomaterials Science Emerging Investigators
23 items

About this collection

Biomaterials Science is proud to present this 2019 Emerging Investigators collection. This collection gathers the very best work from biomaterials scientists in the early stages of their independent careers. The 2019 Biomaterials Science Emerging Investigators were individually nominated by members of the journal Editorial and Advisory Boards, and previous Emerging Investigators, in recognition of their potential to influence future directions in the biomaterials field.

Accompanying this collection is the Emerging Investigators special issue, in which these articles will be formally published. This issue is scheduled for publication in early 2019.

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