Ring-opening metathesis polymerization-induced self-assembly (ROMPISA)
Ring-opening metathesis polymerization-induced self-assembly (ROMPISA) has expanded the preparation of PISA nano-objects beyond radical polymerization approaches. In this highlight article, we summarize current advances and existing challenges in ROMPISA methodologies.
Metal–organic framework gels and monoliths
This perspective links the synthesis of MOF Gels to the formation of MOF-monoliths and their resultant properties and application.
Solution and on-surface synthesis of structurally defined graphene nanoribbons as a new family of semiconductors
Graphene nanoribbons (GNRs) with various structures and properties can be synthesized in solution or on surface.
Visual kinetic analysis
Naked-eye comparison of reaction profiles is a powerful tool to extract mechanistic information – FAQ, video tutorial and templated examples included.
Thermally assisted delayed fluorescence (TADF): fluorescence delayed is fluorescence denied
Thermally assisted delayed fluorescence (TADF) allows for efficient collection of both singlet and triplet excitons with both emitting through the singlet channel. TADF opens the door to photo- and electroluminescence efficiencies close to 100%.
Tailoring the physicochemical properties of solution-processed transition metal dichalcogenides via molecular approaches
In this Feature Article we highlight the tremendous progress in solution-processed transition metal dichalcogenides and the molecular approaches employed to finely tune their physicochemical properties.
Peculiar piezoelectricity of atomically thin planar structures
The real realm and recent advances of piezoelectricity after thinning down to two-dimensional materials have been introduced.
Carbon capture and conversion using metal–organic frameworks and MOF-based materials
This review summarizes recent advances and highlights the structure–property relationship on metal–organic framework-based materials for carbon dioxide capture and conversion.
Critical review of the molecular design progress in non-fullerene electron acceptors towards commercially viable organic solar cells
A critical analysis of the molecular design strategies employed in the recent progress of non-fullerene electron acceptors for organic photovoltaics.
The geometry of periodic knots, polycatenanes and weaving from a chemical perspective: a library for reticular chemistry
The geometry of the most regular polycatenanes and weavings, as an extended family of discrete knots and catenanes, is described in terms of sticks and corners in their optimal embeddings.
Fragmentation reactions using electrospray ionization mass spectrometry: an important tool for the structural elucidation and characterization of synthetic and natural products
This review article explores the most common fragmentation reactions for ions generated by ESI in positive and negative modes.
Soft and hard templating of graphitic carbon nitride
This article reviews recent advances in templating of graphitic carbon nitride materials, with a particular focus on applications in photocatalysis.
Biomimetic carbohydrate recognition
Binding saccharides with non-covalent interactions is challenging, especially in the natural medium of water, but synthetic carbohydrate receptors can be surprisingly effective.
Catalytic cascade reactions by radical relay
Catalytic radical relays are an attractive tool for the rapid construction of complex molecular architectures.
Advances in the synthesis of nitroxide radicals for use in biomolecule spin labelling
The structures and properties of nitroxide radicals can be readily tailored for use as spin labels in biomolecular EPR spectroscopy.
Circular dichroism spectroscopy of membrane proteins
Circular dichroism spectra of helical bundle (red), beta barrel (blue), and mixed helical/sheet/unordered (green) membrane proteins.
The rise of the nanomaterial metabolite corona, and emergence of the complete corona
Metabolites present in the corona may play a key role in biological recognition of nanomaterials yet remain a much-overlooked aspect of the corona.
Coupled techniques for arsenic speciation in food and drinking water: a review
Arsenic is ubiquitous in nature appearing in various chemical forms.
Simultaneous non-covalent bi-functionalization of 1T-MoS2 ruled by electrostatic interactions: towards multi-responsive materials
Dual functionalization of chemically exfoliated MoS2 has been achieved by exploiting coulombic interactions among positively charged molecules and the negatively charged 2D flakes.
High and reversible SO2 capture by a chemically stable Cr(III)-based MOF
MIL-101(Cr)-4F(1%) shows a high uptake and high chemical stability to dry and humid SO2 and a remarkable cyclability. In situ DRIF spectroscopy upon the adsorption of CO identified the preferential adsorption sites for this MOF material.
Selective hydrogenation of lignin-derived compounds under mild conditions
A key challenge in the production of lignin-derived chemicals is to reduce the energy intensive processes used in their production.
A caged E3 ligase ligand for PROTAC-mediated protein degradation with light
Caging of a widely used Von Hippel Lindau E3 ligase ligand for targeted protein degradation with PROTACs allows light-activated proteolysis.
Reductive dehydrocoupling of diphenyltin dihydride with LiAlH4: selective synthesis and structures of the first bicyclo[2.2.1]heptastannane-1,4-diide and bicyclo[2.2.2]octastannane-1,4-diide
The reaction of diphenyltin dihydride with LiAlH4 gives access to a set of charged tin cages as their lithium salts.
The dilemma between acid and base catalysis in the synthesis of benzimidazole from o-phenylenediamine and carbon dioxide
Synthesis of azoles from ortho-substituted anilines and CO2 is limited by the cyclization reaction and not by CO2 reduction.
Band gap modulation in zirconium-based metal–organic frameworks by defect engineering
A simple defect engineering approach to systematically tune the band gap of the prototypical zirconium-based metal–organic framework UiO-66 is reported. Defect engineered materials display enhanced photocatalytic activity.
Bioinspired hydrogel microfibres colour-encoded with colloidal crystals
The integration of microfluidic spinning and colloidal crystal microdots enable the colour-encoded hydrogel microfibres with facile and flexible manipulation of the encoding.
One-pot synthesis of high molar activity 6-[18F]fluoro-L-DOPA by Cu-mediated fluorination of a BPin precursor
A one-pot two-step synthesis of 6-[18F]fluoro-L-DOPA has been developed, involving Cu-mediated radiofluorination of the corresponding pinacol boronate ester precursor, and validated for production of doses for human use.
An organic super-electron-donor as a high energy density negative electrolyte for nonaqueous flow batteries
An organic “super-electron-donor” is well-suited as a negative electrolyte for nonaqueous redox flow batteries, with a highly negative 2+/0 reduction potential, a low mass per electron stored, and good solubility in CH3CN in both redox states.
Microcalorimetry and fluorescence show stable peptide nucleic acid (PNA) duplexes in high organic content solvent mixtures
Peptide nucleic acid (PNA) hybridisation is highly tolerant to the addition of organic solvent. This finding suggests that PNA could enable the use of a range of water-sensitive chemistries in nucleic acid templating applications.
Phenanthro[9,10-d]triazole and imidazole derivatives: high triplet energy host materials for blue phosphorescent organic light emitting devices
A class of wide bandgap host materials is introduced as an alternative to carbazole-based hosts to enhance the efficiency and transport properties of organic light emitting diodes (OLEDs).
High and energy-efficient reversible SO2 uptake by a robust Sc(III)-based MOF
MFM-300(Sc) was demonstrated to be an optimal adsorbent for SO2 capture combining high uptake, good stability and excellent cyclability (facile regeneration at only room temperature). A drastic enhancement on its SO2 uptake (40%) was achieved when a small amount of EtOH was preliminary adsorbed.
Enzymatic synthesis of N-acetyllactosamine from lactose enabled by recombinant β1,4-galactosyltransferases
Synthesis of LacNAc with reversible GalTs.
Reversible insertion of CO into an aluminium–carbon bond
A [2.2.1] aluminium metallobicycle is capable of reversibly inserting CO to form a [2.2.2] metallobicycle at 100 °C.
Dithieno[3,2-b:2′,3′-d]arsole-containing conjugated polymers in organic photovoltaic devices
Dithieno[3,2-b:2′,3′-d]arsole containing donor polymers are reported and investigated in organic solar cell devices for the first time.
Reduction of 1,3,5,7-cyclooctatetraene by a molecular calcium hydride: an even electron polarised insertion/deprotonation mechanism
The reductive aromatisation of 1,3,5,7-cyclooctatetraene by a dimeric calcium hydride occurs via two electron steps and does not necessitate the formation of radical intermediates.
Highly selective chromoionophores for ratiometric Na+ sensing based on an oligoethyleneglycol bridged bithiophene detection unit
A series of nine novel Na+ selective ratiometric optical probes (S1–S9) have been developed and evaluated both by computational and experimental means.
Palladium-catalysed ligand-free reductive Heck cycloisomerisation of 1,6-en-α-chloro-enamides
The first example of an intramolecular hydroarylation of 1,6-en-α-chloro-enamides was achieved by a palladium-catalysed ligand-free reductive Heck cycloisomerisation with no competing Heck-cyclised by-product.
Actinide-transition metal bonding in heterobimetallic uranium– and thorium–molybdenum paddlewheel complexes
Heterobimetallic An–Mo (An = U, Th) paddlewheel complexes featuring dative Mo → An bonds are reported.
Methanol as hydrogen source: transfer hydrogenation of aromatic aldehydes with a rhodacycle
A rhodacycle catalyses efficient hydrogenation of aldehydes, deriving the hydrogen from methanol.
Hydrogen peroxide production via a redox reaction of N,N′-dimethyl-2,6-diaza-9,10-anthraquinonediium by addition of bisulfite
We demonstrate that bisulfite can be used for reduction of a highly electrophilic anthraquinone derivative, N,N′-dimethyl-2,6-diaza-9,10-anthraquinonediium (DAAQ), and subsequent autoxidation generates an equivalent of hydrogen peroxide.
Reductive cyclisations of amidines involving aminal radicals
The first general study of aminal radical cyclisations, triggered by reduction of amidines with SmI2, delivers quinazolinones with complete diastereocontrol.
Elucidation of the roles of conserved residues in the biosynthesis of the lasso peptide paeninodin
Substrate binding assays, in vitro proteolytic processing assays, and heterologous lasso peptide production were used to investigate the roles of conserved precursor peptide residues during paeninodin maturation.
Highly Lewis acidic cationic alkaline earth metal complexes
“Naked” cationic β-diketiminate Mg and Ca complexes possess high Lewis acidities and bind strongly to neutral benzene or alkyne ligands.
Singular wavelength dependence on the sensitization of lanthanides by graphene quantum dots
Graphene quantum dots can photosensitize the emission of terbium cations with a photoluminescence efficiency that increases at shorter wavelengths.
Predicting the frequency of extreme air quality events
A new method for predicting the frequency of extreme air quality events is proposed.
Structural insights into the EthR–DNA interaction using native mass spectrometry
The interaction between Mycobacterium tuberculosis EthR and its operator DNA has been studied by native mass spectrometry, revealing an interesting stoichiometry.
Tandem Rh-catalysis: decarboxylative β-keto acid and alkyne cross-coupling
Herein, we describe a regioselective Rh-catalyzed decarboxylative cross-coupling of β-keto acids and alkynes to access branched γ,δ-unsaturated ketones.
Dithieno[2,3-d;2′,3′-d]benzo[2,1-b;3,4-b‘]dithiophene: a novel building-block for a planar copolymer
A planar heteroacene building block, dithieno[2,3-d;2′,3′-d′]benzo[1,2-b;3,4-b′]dithiophene (DTmBDT), is reported via a facile synthetic procedure.
Heteroleptic actinocenes: a thorium(IV)–cyclobutadienyl–cyclooctatetraenyl–di-potassium-cyclooctatetraenyl complex
We report the first thorium–cyclobutadienyl complex, a new type of heteroleptic actinocene, that exhibits ‘an alkene-like’ thorium–η2-cyclooctatetraenyl interaction.
Two-dimensional, conductive niobium and molybdenum metal–organic frameworks
Incorporation of Nb and Mo into conductive metal–organic frameworks enables utilization of the enhanced covalency, redox activity, and spin–orbit coupling of late-row metals to improve the transport and magnetic properties of these materials.
Self-adjusting binding pockets enhance H2 and CH4 adsorption in a uranium-based metal–organic framework
Optimizing binding pocket geometries in MOFs for ideal interaction with target molecules remains a tremendous synthetic challenge. In the new MOF U(bdc)2, self-adjusting binding pockets flex to bind differently sized guests H2, CH4 and DMF.
Kinetics of cooperative CO2 adsorption in diamine-appended variants of the metal–organic framework Mg2(dobpdc)
An in-depth investigation of the CO2 adsorption kinetics of a promising class of cooperative carbon capture materials offers new insight into their structure-performance properties.
Observation of binding of carbon dioxide to nitro-decorated metal–organic frameworks
Synergistic effects between –NO2 groups and open metal sites lead to optimal binding of CO2 molecules within MFM-102-NO2via hydrogen bonding to C–H groups.
Outer-sphere effects on ligand-field excited-state dynamics: solvent dependence of high-spin to low-spin conversion in [Fe(bpy)3]2+
Time-resolved spectroscopic measurements of ground-state recovery for [Fe(bpy)3]2+ reveal that the solvent can induce an outer-sphere reorganization energy effect on excited-state dynamics involving metal-centered ligand-field electronic states.
Mixing and matching genes of marine and terrestrial origin in the biosynthesis of the mupirocin antibiotics
Where the sea meets the land: the mupirocin biosynthetic gene cluster (BGC) from the terrestrial bacterium Pseudomonas fluorescens was repurposed via a plug-and-play approach with heterologous genes from the marine strain that produces thiomarinol.
Observations of tetrel bonding between sp3-carbon and THF
sp3-C⋯THF tetrel bonding was observed in the crystalline state and in the gas phase. Density functional calculations revealed interaction energies up to −11.2 kcal mol−1 and showed that these adducts are held together mainly by electrostatics.
Functional group interaction profiles: a general treatment of solvent effects on non-covalent interactions
Functional group interaction profiles are a quantitative tool for predicting the effect of solvent on the free energy changes associated with non-covalent interactions.
SAXS studies of the thermally-induced fusion of diblock copolymer spheres: formation of hybrid nanoparticles of intermediate size and shape
Dilute dispersions of poly(lauryl methacrylate)-poly(benzyl methacrylate) diblock copolymer spheres of differing mean diameter are mixed and thermally annealed at 150 °C to produce either spherical or non-spherical nanoparticles of intermediate size.
Proton-coupled electron transfer across benzimidazole bridges in bioinspired proton wires
Experimental and theoretical methods characterize the thermodynamics of electrochemically driven proton-coupled electron transfer processes in bioinspired constructs involving multiple proton translocations over Grotthus-type proton wires.
Selective glucose sensing in complex media using a biomimetic receptor
A highly selective receptor, circular dichroism and chiral competition are combined in this versatile method for D-glucose analysis.
Dynamic design: manipulation of millisecond timescale motions on the energy landscape of cyclophilin A
Molecular simulations were used to design large scale loop motions in the enzyme cyclophilin A and NMR and biophysical methods were employed to validate the models.
A borane-mediated palladium-catalyzed reductive allylic alkylation of α,β-unsaturated carbonyl compounds
A palladium-catalyzed allylation of ester-derived boron enolates, which is prepared through 1,4-reduction of α,β-unsaturated ester analogues.
Sulfoxide-mediated oxidative cross-coupling of phenols
A metal-free, oxidative coupling of phenols with various nucleophiles, including arenes, 1,3-diketones and other phenols, is reported.
A photo-regulated aptamer sensor for spatiotemporally controlled monitoring of ATP in the mitochondria of living cells
A photo-regulated ATP sensor coupled with cationic DQAsomes is developed for spatiotemporally controlled imaging of ATP in the mitochondria of living cells.
Chemical biology tools for probing transcytosis at the blood–brain barrier
A BBB vehicle library is validated, establishing a SAR for uptake. Merging AMT/RMT motifs chemoselectively increased permeability.
Electrochemical C–H bond activation via cationic iridium hydride pincer complexes
Electrochemical C–H activation proceeds at room temperature upon oxidation of a pincer-ligated iridium complex in the presence of base.
Mechanistic studies of a “Declick” reaction
Detailed kinetic analysis reveals a complex multi-step mechanism for an amine-thiol “declick” reaction.
The partial dehydrogenation of aluminium dihydrides
The reactions of a series of β-diketiminate stabilised aluminium dihydrides with ruthenium bis(phosphine), palladium bis(phosphine) and palladium cyclopentadienyl complexes is reported.
Development of 68Ga-labelled ultrasound microbubbles for whole-body PET imaging
We report a rapid and efficient method for labelling ultrasound microbubble (MB) agents with a generator-produced PET isotope using a facile ligation between a trans-cyclooctene-modified phospholipid and a new 68Ga-HBED-CC-tetrazine tracer. This method provides accessible solutions for in vivo tracking of MBs.
Modulating proton diffusion and conductivity in metal–organic frameworks by incorporation of accessible free carboxylic acid groups
The proton conductivity of barium-based MOFs MFM-510 to MFM-512 are analysed in relation to the absence and presence of free –COOH groups in the pores.
About this collection
In celebration of the 2020 Royal Society of Chemistry prizes and awards, we have collected together some of the exciting research recently published by the winners. This collection showcases articles authored by the winners from across the Royal Society of Chemistry’s journals portfolio – these articles are free to access until 30th September 2020.
Learn more about the 2020 Royal Society of Chemistry prizes and award winners here.
Why not also have a look at last year’s collection of articles by our 2019 winners here.