Themed collection 2025 Reviews in RSC Advances

This review highlights the advantages of optimizing various DSSC components, such as Ru(II)-polypyridyl photosensitizers, co-adsorbents, electrolytes, electrolyte additives, and counter electrodes, to improve the overall performance of DSSCs.

This review explores the pathology of SCI and the characteristics of GBMs, focusing on recent in vitro and in vivo research on their mechanism, biocompatibility, toxicity, and biodegradability.

The tremendous potential of transition metal-free multi-component reactions (MCR) in the synthesis of N-heterocyclic frameworks is examined in this review, offering a complete overview of this subject matter.

The pharmacological significance of benzimidazoles was reviewed.

Advancements in 3D biomaterials for wound healing and tissue engineering applications. Created in BioRender. Dhilip Kumar S. (2025) https://BioRender.com/q54m087.

In this review, we summarize the recent advances in the synthesis of 2-aminophenoxazinone frameworks based on different catalytic approaches and synthetic process routes of 2-aminophenoxazinone compounds.

With the ongoing advancements in wireless communication and electronic technology, the issue of electromagnetic radiation (EMR) pollution has become increasingly significant.

Double pyramid model, serves as an integrated health approach to food, linking food culture, health, and climate. Adapted from Barilla Foundation, in conjunction with the University of Naples Federico II. 2021.

As the demand for efficient and high-performance energy storage devices continues to rise, supercapacitors have emerged as a promising technology due to their rapid charge–discharge capabilities and long cycle life.

This review provides an account of the site-selective cleavage of peptides and proteins at the aromatic amino acid residues, developed over the last seven decades (1958–2024).

Cortistatins and plakinamines represent a unique class of marine-derived steroidal alkaloids, renowned for their structural diversity and potent pharmacological activities.

Aqueous two-phase system (ATPS) epitomize a remarkable phenomenon where two immiscible phases manifest through the amalgamation of at least two water-soluble components at precise concentrations.

MXenes, which are essentially 2D layered structures composed of transition metal carbides and nitrides obtained from MAX phases.

Silver nanoparticle (AgNP)-polymer nanocomposites offer enhanced antimicrobial properties for biomedical applications, including medical devices and implants. Stability and biocompatibility remain key challenges to apply AgNPs in biomedical fields.

This review discusses the extraction of critical metals (Li, Co, and Ni) using ionic liquids.

Achieving carbon neutrality and mitigating global warming through efficient CO₂ reduction, by utilizing synergistic bimetallic Fe-based catalysts for enhanced electrochemical performance and selectivity.

Recent advances in synthetic strategies of isoxazoles and their role in medicinal chemistry.

This study conducted a bibliometric analysis of sludge-based materials for environmental remediation, highlighting trends, research hotspots, and future directions, focusing on advanced modifications and sustainability.

Corey–Fuchs reaction is a two-step reaction involving the synthesis of terminal alkyne from aldehyde. It is a pivotal organic reaction, plays a significant role in the synthesis of various natural products and their derivatives.

This review examines the limitations of LIBs at low temperatures, discusses advancements in electrolyte components and novel formulations, and proposes future strategies to improve performance under extreme conditions.

Cancer, an insidious affliction, continues to exact a heavy toll on humanity, necessitating early detection and nuanced comprehension of its intricacies for effective treatment.

Durable antimicrobial coatings has emerged as the one of most promising strategies for reducing the accumulation of microorganisms on high-touch surfaces. In this group, light-activated layers are of particular interest, as they are effective against broad range of pathogens.

Wearable sensors have emerged as a transformative technology, enabling real-time monitoring and advanced functionality in various fields, including healthcare, human–machine interaction, and environmental sensing.

Onychomycosis significantly impacts approximately 20% of the global population.

The current advances in energy storage devices has necessitated the development of functional polymer-based nanocomposites for supercapacitor applications.

TADF materials enable high-efficiency light emission via reverse intersystem crossing. Advanced designs enhance their role in OLEDs, photocatalysis, and bioimaging, offering tunable optoelectronic properties for next-generation applications.

Pyrazole and its derivatives have attracted considerable attention in pharmaceutical and medicinal chemistry, as reflected in their presence in numerous FDA-approved drugs and clinical candidates.

Hydrazone-based compounds distinguished by their azomethine –NHNCH group and their respective coinage metal complexes have emerged as leading candidates in the search for effective anticancer and antibiotic agents.

Metal oxide nanoparticles and their composites have garnered significant attention in water treatment and environmental cleanup due to their unique physicochemical properties.

BOPP (Biaxially Oriented Polypropylene)//TiO_x/Al composite films with “laminated” structure were prepared by vacuum evaporation and layer-by-layer coating.

The paper presents the results of a study of the influence of various fillers on the structural features and quality of composite and nanocomposite materials based on polyolefins and their modifications.

Ball milling, as an efficient material processing technique, has been widely applied in the preparation and modification of sodium-ion battery anode materials in recent years.

This review describes the coupling of semiconducting materials with perovskites as main optically active elements for enhancing the performance depending on the optical set-up and coupling phenomena.

Schematic illustration of several synthetic forms of 2D and 3D DNA nanotechnology combined with CRISPR/Cas systems in biotechnology.

This article provides an overview of various synthetic approaches to 1,4-benzothiazines using a range of substrates over the last decade (2014–2024).

Lithium–sulfur (Li–S) batteries have garnered significant attention as promising next-generation energy storage solutions due to their high energy density and cost efficiency.

This is an updated review for the anticancer activity of benzodiazine heterocyclic derivatives through kinase inhibition.

Background: H. pylori is recognized as one of the main causes of gastric cancer, and this type of cancer is considered as one of the leading diseases causing cancer deaths all over the world.

Traditional Chinese Medicine (TCM) formulas, based on the principles of Chinese medicine, have a long history and are widely applied in the treatment of diseases.

Metal NPs cross BBB and release low drug doses in a time-controlled manner in the target site. AuNPs and IONPs predominantly inhibit neuroinflammation, while other metal NPs promote it. Metal NPs possess dual role in modulating microglia.

The Mitsunobu reaction is a key bimolecular nucleophilic substitution for synthesizing chiral products. This paper highlights its importance in synthesizing biologically active compounds, focusing on forming C–N single bonds.

In recent years, the development and use of nanomaterials have transformed numerous aspects of biomedical science.

The work provides a systematic and critical overview of the cutting-edge research on SPs and hybrid sulfated polysaccharide bio-nanocomposites and identifies the key factors, mechanisms, methods, and challenges impacting SPs bio-nanocomposites.

This review focuses clinical significance of CysC detection followed by detailed analysis of different CysC biosensing methods with emphasis on the necessity of PoC monitoring of CysC.

A schematic illustrating the initial characteristics, phases, nanostructures, and potential future applications of 1D TiO₂ photoanodes.

Sources of metal contamination, metal transfer pathways, and remediation approaches.

This review covers recent advancements in Diels–Alder reaction chemistry for total synthesis of Natural Products (2020–2023) and, where relevant, discusses key structural features and biological activity of bioactive natural products.

Overview of gold nanoparticle synthesis using binary surfactants: key mechanisms and future directions.

Itaconate and its derivatives.

The present review attempts to evaluate the applicability of deep eutectic solvents (DES) as a green technique for the extraction of phytochemicals from Mangifera indica L. and their therapeutic potential.

Alzheimer's disease (AD) is a devastating neurodegenerative disorder with no effective disease-modifying treatments.

A sustainable and viable alternative for conventional chemical and physical approaches is the green production of silver nanoparticles (SNPs) using plant extracts.

This review studies magnetically recoverable catalysts designed for the efficient multicomponent synthesis of organosulfur compounds. These catalysts enhance the synthesis process by combining efficiency with environmental sustainability.

Pyrazolo[1,5-a]pyrimidines are a notable class of heterocyclic compounds with potent protein kinase inhibitor (PKI) activity, playing a critical role in targeted cancer therapy.

Graphical representation of quinoline-based molecular frameworks: synthesis and structural diversity.

Furonaphthoquinones and their dihydro derivatives have attracted significant attention due to their diverse pharmacological activities.

Purines as precursor pharmacophores in chemical reactions.

Hydrazone-based fluorescent sensors have been instrumental for the detection of toxic metals over the past decade due to their ease of synthesis and unique properties.

In recent years, nucleobases have attracted special attention because of their abundant resources and multiple interaction sites, which enable them to interact with and functionalize other molecules.

Asymmetric catalytic reactions are essential for synthesizing chiral drugs and fine chemicals, with their stereoselectivity influenced significantly by interactions between catalysts and substrates.

Imperious role of biogenically obtained selenium nanoparticles to abate the alarming accumulation of harmful wastes as a result of rapidly growing industrialisation and globally increased economic activities.

Effective and ecofriendly remediation techniques are important for the removal of arsenic species from drinking water.

Escalating energy demands have often ignited ground-breaking innovations in the current era of electrochemical energy storage systems.

Triazole, a nitrogen-containing five-membered heterocycle with two isomeric forms, 1,2,3-triazole and 1,2,4-triazole, has proven to be a valuable component in the pharmaceutical domain.

In the past two decades, organic solar cells (OSCs) have begun to attract attention as the efficiency of inorganic solar cells gradually approaches the theoretical limit.

Benzo-fused γ-lactams are fundamental in medicinal chemistry, acting as essential elements for various therapeutic agents due to their structural adaptability and capability to enhance biological activity.

Advancing the development of organelle-targeted small fluorescent probes by highlighting key design strategies to reveal cellular dynamics and address persistent challenges in probe design.

Sesquiterpene lactones (SLs) are a structurally diverse group of secondary metabolites primarily produced by plants, particularly within the Asteraceae family.

Bioactives for the treatment of cancer.

We have reviewed the recently reported multicomponent reactions (MCRs) yielding cyclic frameworks in a single pot from simple building blocks under mild conditions. These MCRs may prove to be useful for drug discovery projects.