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Themed collection Catalysis & biocatalysis in OBC

72 items - Showing page 1 of 2
Review Article

The catalytic Mitsunobu reaction: a critical analysis of the current state-of-the-art

This Review article provides a summary and critical metrics-based analysis of recently developed catalytic Mitsunobu reactions.

Graphical abstract: The catalytic Mitsunobu reaction: a critical analysis of the current state-of-the-art
From the themed collection: Synthetic methodology in OBC
Review Article

Indium(III) as π-acid catalyst for the electrophilic activation of carbon–carbon unsaturated systems

This review focuses on indium(III) as a π-acid for the activation of C–C unsaturated systems (alkynes, alkenes, and allenes) in organic synthesis.

Graphical abstract: Indium(iii) as π-acid catalyst for the electrophilic activation of carbon–carbon unsaturated systems
From the themed collection: Catalysis & biocatalysis in OBC
Review Article

Dibenzofuran-4,6-bis(oxazoline) (DBFOX). A novel trans-chelating bis(oxazoline) ligand for asymmetric reactions

The trans-chelating bis(oxazoline) ligand (R,R)-4,6-dibenzofurandiyl-2,2′-bis(4-phenyloxazoline) [(R,R)-DBFOX/Ph] coordinates metal ions to give C2-symmetric complexes which effectively catalyze a variety of asymmetric reactions.

Graphical abstract: Dibenzofuran-4,6-bis(oxazoline) (DBFOX). A novel trans-chelating bis(oxazoline) ligand for asymmetric reactions
From the themed collection: Catalysis & biocatalysis in OBC
Review Article

Asymmetric iodine catalysis-mediated enantioselective oxidative transformations

The implementation of chiral iodine catalysis has tremendously been developed in the field of asymmetric synthesis over the past decade.

Graphical abstract: Asymmetric iodine catalysis-mediated enantioselective oxidative transformations
From the themed collection: Catalysis & biocatalysis in OBC
Review Article

Development and application of chiral spirocyclic phosphoric acids in asymmetric catalysis

This review describes the synthetic methods for the preparation of chiral spirocyclic phosphoric acids (SPAs), and their dynamically developing application for catalytic enantioselective transformations.

Graphical abstract: Development and application of chiral spirocyclic phosphoric acids in asymmetric catalysis
From the themed collection: Catalysis & biocatalysis in OBC
Review Article

Halo-substituted benzenesulfonyls and benzenesulfinates: convenient sources of arenes in metal-catalyzed C–C bond formation reactions for the straightforward access to halo-substituted arenes

The use of halo-substituted ArSO2R as an aryl source in metal-catalyzed C–C bond formation reactions presents several advantages, as the reaction often proceeds without cleavage of the C–halo bonds.

Graphical abstract: Halo-substituted benzenesulfonyls and benzenesulfinates: convenient sources of arenes in metal-catalyzed C–C bond formation reactions for the straightforward access to halo-substituted arenes
From the themed collection: Catalysis & biocatalysis in OBC
Review Article

Chiral proton-transfer shuttle catalysts for carbene insertion reactions

The development of chiral proton-transfer shuttles provides a totally new enantiocontrol strategy for transition metal-catalyzed asymmetric carbene insertion reactions.

Graphical abstract: Chiral proton-transfer shuttle catalysts for carbene insertion reactions
From the themed collection: Catalysis & biocatalysis in OBC
Review Article

Recent advances in iodine mediated electrochemical oxidative cross-coupling

This review article gives an overview of the recent development of iodine mediated electrochemical oxidative coupling reactions.

Graphical abstract: Recent advances in iodine mediated electrochemical oxidative cross-coupling
From the themed collection: Catalysis & biocatalysis in OBC
Review Article

Catalytic asymmetric enamine protonation reaction

Recent advances in catalytic enantioselective enamine protonation for the synthesis of optically active carbonyl compounds are summarized in this review.

Graphical abstract: Catalytic asymmetric enamine protonation reaction
From the themed collection: Catalysis & biocatalysis in OBC
Open Access Review Article

Enhanced structural diversity in terpenoid biosynthesis: enzymes, substrates and cofactors

Terpenoid structural diversity is enhanced by multiproduct enzymes. Biosynthesis can be altered by switch in substrates, cofactors and pH.

Graphical abstract: Enhanced structural diversity in terpenoid biosynthesis: enzymes, substrates and cofactors
From the themed collection: Catalysis & biocatalysis in OBC
Communication

Iron(III)-catalyzed radical α,β-aminophosphinoylation of styrenes with diphenylphosphine oxides and anilines

A Fe-catalyzed highly regioselective α,β-difunctionalization of vinylarenes with diphenylphosphine oxides and anilines is disclosed, in which α,β-aminophosphinoylation is efficiently and conveniently constructed with good functional compatibility and a broad substrate scope.

Graphical abstract: Iron(iii)-catalyzed radical α,β-aminophosphinoylation of styrenes with diphenylphosphine oxides and anilines
From the themed collection: Catalysis & biocatalysis in OBC
Accepted Manuscript - Communication

Direct synthesis of indenes via a rhodium-catalyzed multicomponent Csp2—H annulation reaction

From the themed collection: Catalysis & biocatalysis in OBC
Communication

Metal-free visible-light synthesis of quaternary α-perfluoroalkyl aldehydes via an enamine intermediate

Visible-light induced perfluoroalkylation of the α-position of aldehydes via enamines.

Graphical abstract: Metal-free visible-light synthesis of quaternary α-perfluoroalkyl aldehydes via an enamine intermediate
From the themed collection: Synthetic methodology in OBC
Accepted Manuscript - Communication

Enantioselective biocatalytic formal α-amination of hexanoic acid to L-norleucine

From the themed collection: Catalysis & biocatalysis in OBC
Communication

Palladium-catalyzed heck-type cascade cyclization of (Z)-1-iodo-1,6-dienes with N-tosyl hydrazones

A new way to synthesize tetrahydropyridine derivatives bearing a terminal alkene due to highly regioselective β-H elimination of alkylpalladium species.

Graphical abstract: Palladium-catalyzed heck-type cascade cyclization of (Z)-1-iodo-1,6-dienes with N-tosyl hydrazones
From the themed collection: Catalysis & biocatalysis in OBC
Communication

Rhodium(III)-catalyzed three-component cascade synthesis of 6H-benzo[c]chromenes through C–H activation

An efficient procedure for 6H-benzo[c]chromenes via a new Rh(III)-catalyzed domino annulation is described.

Graphical abstract: Rhodium(iii)-catalyzed three-component cascade synthesis of 6H-benzo[c]chromenes through C–H activation
From the themed collection: Synthetic methodology in OBC
Communication

Gold(I)-catalysed high-yielding synthesis of indenes by direct Csp3–H bond activation

A catalytic, practical and high-yielding procedure for the synthesis of indenes by direct Csp3–H activation under gold(I) catalysis was developed.

Graphical abstract: Gold(i)-catalysed high-yielding synthesis of indenes by direct Csp3–H bond activation
From the themed collection: Catalysis & biocatalysis in OBC
Communication

Organocatalytic asymmetric Michael/hemiketalization/acyl transfer reaction of 1,3-propanediones with (E)-2-(2-nitrovinyl)phenols

An organocatalytic asymmetric cascade Michael/hemiketalization/acyl transfer reaction between (E)-2-(2-nitrovinyl)phenols and 1,3-propanediones is disclosed to generate products having keto, ester and nitro functionalities.

Graphical abstract: Organocatalytic asymmetric Michael/hemiketalization/acyl transfer reaction of 1,3-propanediones with (E)-2-(2-nitrovinyl)phenols
From the themed collection: Catalysis & biocatalysis in OBC
Communication

Nickel catalyzed site selective C–H functionalization of α-aryl-thioamides

A nickel catalyzed C–H bond functionalization reaction has been used for the first time to study an intramolecular site-selective C–S bond formation of arenes.

Graphical abstract: Nickel catalyzed site selective C–H functionalization of α-aryl-thioamides
From the themed collection: Catalysis & biocatalysis in OBC
Communication

Synthesis and application of a new chiral monodentate spiro phosphoramidite ligand based on hexamethyl-1,1′-spirobiindane backbone in asymmetric hydroamination/arylation of alkenes

A new chiral monodentate spiro phosphoramidite ligand based on a hexamethyl-1,1′-spirobiindane scaffold has been developed and applied in Pd-catalyzed asymmetric hydroamination/arylation of alkenes.

Graphical abstract: Synthesis and application of a new chiral monodentate spiro phosphoramidite ligand based on hexamethyl-1,1′-spirobiindane backbone in asymmetric hydroamination/arylation of alkenes
From the themed collection: Catalysis & biocatalysis in OBC
Communication

An organocatalytic asymmetric Mannich reaction for the synthesis of 3,3-disubstituted-3,4-dihydro-2-quinolones

An organocatalytic asymmetric Mannich reaction between 3-cyano-3,4-dihydroquinolones and amidosulfones has been developed to construct biologically important 3,3-disubstituted 3,4-dihydroquinolones.

Graphical abstract: An organocatalytic asymmetric Mannich reaction for the synthesis of 3,3-disubstituted-3,4-dihydro-2-quinolones
From the themed collection: Catalysis & biocatalysis in OBC
Communication

A new route to substituted furocoumarins via copper-catalyzed cyclization between 4-hydroxycoumarins and ketoximes

A new route to substituted furocoumarins via copper-catalyzed cyclization between 4-hydroxycoumarins and ketoximes was developed.

Graphical abstract: A new route to substituted furocoumarins via copper-catalyzed cyclization between 4-hydroxycoumarins and ketoximes
From the themed collection: Catalysis & biocatalysis in OBC
Communication

An organocatalyst bound α-aminoalkyl radical intermediate for controlled aerobic oxidation of iminium ions

A nucleophilic catalyst is introduced for facile radical formation and its catalyst controlled aerobic oxidation.

Graphical abstract: An organocatalyst bound α-aminoalkyl radical intermediate for controlled aerobic oxidation of iminium ions
From the themed collection: Catalysis & biocatalysis in OBC
Communication

Electrochemical Hofmann rearrangement mediated by NaBr: practical access to bioactive carbamates

An electrochemical Hofmann rearrangement is reported, which provides general and practical access to bioactive carbamates.

Graphical abstract: Electrochemical Hofmann rearrangement mediated by NaBr: practical access to bioactive carbamates
From the themed collection: Catalysis & biocatalysis in OBC
Communication

Cobalt-catalyzed carbon–sulfur/selenium bond formation: synthesis of benzo[b]thio/selenophene-fused imidazo[1,2-a]pyridines

An efficient cobalt-catalyzed C–S/C–Se bond formation method for the synthesis of benzo[b]thio/selenophene-fused imidazo[1,2-a]pyridines has been developed.

Graphical abstract: Cobalt-catalyzed carbon–sulfur/selenium bond formation: synthesis of benzo[b]thio/selenophene-fused imidazo[1,2-a]pyridines
From the themed collection: Catalysis & biocatalysis in OBC
Communication

Bifunctional catalysis in the stereocontrolled synthesis of tetrahydro-1,2-oxazines

The application of bifunctional catalysis for the synthesis of tetrahydro-1,2-oxazines is described.

Graphical abstract: Bifunctional catalysis in the stereocontrolled synthesis of tetrahydro-1,2-oxazines
From the themed collection: Catalysis & biocatalysis in OBC
Communication

Rh(III)-Catalyzed ortho-C–H alkynylation of N-phenoxyacetamides with hypervalent iodine-alkyne reagents at room temperature

Directing group ONHR preserved ortho-alkynylation under mild conditions catalyzed by rhodium is reported.

Graphical abstract: Rh(iii)-Catalyzed ortho-C–H alkynylation of N-phenoxyacetamides with hypervalent iodine-alkyne reagents at room temperature
From the themed collection: Catalysis & biocatalysis in OBC
Communication

A biocatalytic cascade for the amination of unfunctionalised cycloalkanes

Here we describe a one-pot, three-enzyme, cascade involving a cytochrome P450 monooxygenase, an alcohol dehydrogenase and a reductive aminase for the synthesis of secondary amines from cycloalkanes.

Graphical abstract: A biocatalytic cascade for the amination of unfunctionalised cycloalkanes
From the themed collection: Catalysis & biocatalysis in OBC
Communication

Organocatalytic umpolung annulative dimerization of ynones for the synthesis of 5-alkylidene-2-cyclopentenones

A novel phosphine-catalyzed umpolung [3 + 2]-annulative dimerization of ynones was developed to furnish functionally rich 5-alkylidene-2-cyclopentenones.

Graphical abstract: Organocatalytic umpolung annulative dimerization of ynones for the synthesis of 5-alkylidene-2-cyclopentenones
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Synthesis of medium-sized (6–7–6) ring compounds by iron-catalyzed dehydrogenative C–H activation/annulation

Iron-catalyzed synthesis of fused seven-membered ring compounds by intramolecular hydroarylation of alkynes.

Graphical abstract: Synthesis of medium-sized (6–7–6) ring compounds by iron-catalyzed dehydrogenative C–H activation/annulation
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Ru-Catalyzed dehydrogenative synthesis of antimalarial arylidene oxindoles

Ru(II)-NHC catalyzes α-olefination of 2-oxindole via dehydrogenative coupling of 2-oxindole and diaryl methanol to generate selectively antimalarial 3-(diphenylmethylene)indolin-2-one derivatives.

Graphical abstract: Ru-Catalyzed dehydrogenative synthesis of antimalarial arylidene oxindoles
From the themed collection: Synthetic methodology in OBC
Accepted Manuscript - Paper

Manganese Catalyzed N-Alkylation of Amines with Alcohols: Ligand Enabled Selectivity

From the themed collection: Catalysis & biocatalysis in OBC
Paper

Synthesis of highly rigid phosphine–oxazoline ligands for palladium-catalyzed asymmetric allylic alkylation

Rigid phosphine–oxazoline ligands with a spirocarbon stereogenic center were developed, which exhibited excellent catalytic performance for Pd-catalyzed allylic alkylation reactions.

Graphical abstract: Synthesis of highly rigid phosphine–oxazoline ligands for palladium-catalyzed asymmetric allylic alkylation
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Asymmetric fluorination of indanone-2-carboxylates using a polystyrene-supported diphenylamine-linked bis(oxazoline) complex

A novel polystyrene-supported diphenylamine-linked bis(oxazoline) complex was developed for asymmetric fluorination in continuous flow, showing high activity and excellent enantioselectivity with a high turnover number.

Graphical abstract: Asymmetric fluorination of indanone-2-carboxylates using a polystyrene-supported diphenylamine-linked bis(oxazoline) complex
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Formal reductive addition of acetonitrile to aldehydes and ketones

Aldehydes and ketones can be converted to nitriles with two extra carbons in one step with TON up to 5600.

Graphical abstract: Formal reductive addition of acetonitrile to aldehydes and ketones
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Organocatalysis and catalyst aggregation: a study using the asymmetric synthesis of benzofuranones as a test reaction

An aggregation phenomenon involving Cinchona alkaloid derivatives deeply affects the performance of the catalyst in an organocatalytic process – a mechanistic study.

Graphical abstract: Organocatalysis and catalyst aggregation: a study using the asymmetric synthesis of benzofuranones as a test reaction
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Enantioselective synthesis of α-perfluoroalkylated prolines, their 6,7-membered homologues and derivatives

The highly enantioselective Strecker reaction with alpha-perfluoroalkylated cyclic ketimines was reported. The corresponding asymmetric cyclic nitriles are a useful tool for obtaining amino acids and their derivatives.

Graphical abstract: Enantioselective synthesis of α-perfluoroalkylated prolines, their 6,7-membered homologues and derivatives
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Structure-based protein engineering enables prenyl donor switching of a fungal aromatic prenyltransferase

Structure-guided molecular modelling and site-directed mutagenesis of the tryptophan dimethylallyl transferase FgaPT2 led to creation of mutants with strongly enhanced activities towards geranyl and farnesyl diphosphates.

Graphical abstract: Structure-based protein engineering enables prenyl donor switching of a fungal aromatic prenyltransferase
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Dirhodium(II)/P(t-Bu)3 catalyzed tandem reaction of α,β-unsaturated aldehydes with arylboronic acids

Axially alkylphosphane ligated Rh2(OAc)4 catalyzes the tandem reaction of α,β-unsaturated aldehydes with arylboronic acids to produce ketone derivatives in high yields.

Graphical abstract: Dirhodium(ii)/P(t-Bu)3 catalyzed tandem reaction of α,β-unsaturated aldehydes with arylboronic acids
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Boronic acid-catalysed C-3 selective ring opening of 3,4-epoxy alcohols with thiophenols and thiols

A boronic acid-catalysed C-3 selective ring opening of 3,4-epoxy alcohols with thiophenols and thiols as nucleophiles has been accomplished.

Graphical abstract: Boronic acid-catalysed C-3 selective ring opening of 3,4-epoxy alcohols with thiophenols and thiols
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Mutated variants of squalene-hopene cyclase: enzymatic syntheses of triterpenes bearing oxygen-bridged monocycles and a new 6,6,6,6,6-fusded pentacyclic scaffold, named neogammacerane, from 2,3-oxidosqualene

First enzymatic syntheses of triterpenes bearing a 7-oxabicyclo[2.2.1]heptane moiety and a novel scaffold, named neogammacerane, by the mutated cyclases.

Graphical abstract: Mutated variants of squalene-hopene cyclase: enzymatic syntheses of triterpenes bearing oxygen-bridged monocycles and a new 6,6,6,6,6-fusded pentacyclic scaffold, named neogammacerane, from 2,3-oxidosqualene
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Rhodium-catalyzed cyclization of acceptor-substituted biphenyl α-diazoketones: a study of the substitution effect on chemoselectivity

A range of biphenyl α-diazoketones containing different α-electron withdrawing groups exhibits divergent chemoselectivity toward rhodium(II) catalysis, delivering phenanthrols, benz[α]azulenones, aromatic ketones and/or 1,2-diketones in varying ratios.

Graphical abstract: Rhodium-catalyzed cyclization of acceptor-substituted biphenyl α-diazoketones: a study of the substitution effect on chemoselectivity
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Synthesis of indole-fused heteroacenes by cascade cyclisation involving rhodium(II)-catalysed intramolecular C–H amination

Indole-fused heteroacenes have been synthesised from cascade cyclisation of 2-[(2-azidophenyl)ethynyl]anilines and -phenols in a catalytic manner under redox-neutral conditions.

Graphical abstract: Synthesis of indole-fused heteroacenes by cascade cyclisation involving rhodium(ii)-catalysed intramolecular C–H amination
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Visible light-induced aerobic oxidative cross-coupling of glycine esters with α-angelicalactone: a facile pathway to γ-lactams

A rapid synthesis of substituted γ-lactams is achieved via metal-free photocatalyzed aerobic oxidative dehydrogenative formal [2 + 3] cyclization of glycine esters with α-angelicalactone.

Graphical abstract: Visible light-induced aerobic oxidative cross-coupling of glycine esters with α-angelicalactone: a facile pathway to γ-lactams
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Switching a regular tryptophan C4-prenyltransferase to a reverse tryptophan-containing cyclic dipeptide C3-prenyltransferase by sequential site-directed mutagenesis

The site-directed mutagenesis of FgaPT2 switches a regular C4-prenylation to a reverse C3-prenylation of tryptophan-containing cyclic dipeptides.

Graphical abstract: Switching a regular tryptophan C4-prenyltransferase to a reverse tryptophan-containing cyclic dipeptide C3-prenyltransferase by sequential site-directed mutagenesis
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Reduction of aromatic nitriles into aldehydes using calcium hypophosphite and a nickel precursor

The reduction of aromatic nitriles to aldehydes is performed with good to excellent yields and selectivities. Calcium hypophosphite is used in the presence of nickel(II) catalyst and base in a water/ethanol system.

Graphical abstract: Reduction of aromatic nitriles into aldehydes using calcium hypophosphite and a nickel precursor
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Nickel-catalysed radical tandem cyclisation/arylation: practical synthesis of 4-benzyl-3,3-difluoro-γ-lactams

Enabled by nickel catalysis, the first radical tandem cyclization–arylation for the synthesis of 4-benzyl-3,3-difluoro-γ-lactams has been developed.

Graphical abstract: Nickel-catalysed radical tandem cyclisation/arylation: practical synthesis of 4-benzyl-3,3-difluoro-γ-lactams
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Asymmetric synthesis of warfarin and its analogs catalyzed by C2-symmetric squaramide-based primary diamines

Novel C2-symmetric N,N′-bis(2-amino-1,2-diphenylethyl)squaramides with 1,2-di(pyridin-2-yl)ethane and 1,2-diphenylethane spacer groups were designed and applied as organocatalysts in asymmetric additions of 4-hydroxycoumarin and 4-hydroxy-6-methyl-2H-pyran-2-one to α,β-unsaturated ketones.

Graphical abstract: Asymmetric synthesis of warfarin and its analogs catalyzed by C2-symmetric squaramide-based primary diamines
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Chemoselective N–H functionalization of indole derivatives via the Reissert-type reaction catalyzed by a chiral phosphoric acid

An asymmetric N-alkylation of indole derivatives via the Reissert-type reaction was realized in the presence of 10 mol% chiral phosphoric acid.

Graphical abstract: Chemoselective N–H functionalization of indole derivatives via the Reissert-type reaction catalyzed by a chiral phosphoric acid
From the themed collection: Synthetic methodology in OBC
Paper

Chemoenzymatic macrocycle synthesis using resorcylic acid lactone thioesterase domains

Resorcylate acid lactone thioesterases can synthesize a variety of macrolactone and macrolactams, as well as a cyclicdepsipeptide.

Graphical abstract: Chemoenzymatic macrocycle synthesis using resorcylic acid lactone thioesterase domains
From the themed collection: Synthetic methodology in OBC
Paper

Cobalt(II)-catalyzed regioselective C–H halogenation of anilides

A cobalt-catalyzed regioselective C–H halogenation methodology is reported herein.

Graphical abstract: Cobalt(ii)-catalyzed regioselective C–H halogenation of anilides
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Cyclotrimerization of phenylacetylene catalyzed by a cobalt half-sandwich complex embedded in an engineered variant of transmembrane protein FhuA

An (η5-cyclopentadienyl)cobalt(I) complex was covalently incorporated in an engineered variant of the β-barrel protein FhuA. The new biohydrid catalyst cyclotrimerized phenylacetylene to give regioisomeric triphenylbenzenes.

Graphical abstract: Cyclotrimerization of phenylacetylene catalyzed by a cobalt half-sandwich complex embedded in an engineered variant of transmembrane protein FhuA
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Palladium-catalyzed selective synthesis of 3,4-dihydroquinazolines from electron-rich arylamines, electron-poor arylamines and glyoxalates

Palladium-catalyzed selective synthesis of various 3,4-dihydroquinazolines from electron-rich arylamines, electron-poor arylamines and glyoxalates was developed.

Graphical abstract: Palladium-catalyzed selective synthesis of 3,4-dihydroquinazolines from electron-rich arylamines, electron-poor arylamines and glyoxalates
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Synthesis of topologically constrained naphthalimide appended palladium(II)–N-heterocyclic carbene complexes – insights into additive controlled product selectivity

Pd(II)–NHC catalyzed regioselective heteroannulation of o-haloanilines and arylethynyl-trimethylsilane to yield indoles and additive controlled switchable product selectivity has been demonstrated.

Graphical abstract: Synthesis of topologically constrained naphthalimide appended palladium(ii)–N-heterocyclic carbene complexes – insights into additive controlled product selectivity
From the themed collection: Catalysis & biocatalysis in OBC
Paper

High pressure-assisted low-loading asymmetric organocatalytic conjugate addition of nitroalkanes to chalcones

A highly enantioselective and relatively fast (1–5 h) Michael reaction with substantial reduction of organocatalyst loading (0.2–1 mol%) was developed under high-pressure conditions (up to 9 kbar) and at room temperature.

Graphical abstract: High pressure-assisted low-loading asymmetric organocatalytic conjugate addition of nitroalkanes to chalcones
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Comparison of riboflavin-derived flavinium salts applied to catalytic H2O2 oxidations

A series of flavinium salts were prepared from commercially available riboflavin, and their optical and redox properties and their catalytic activity were compared.

Graphical abstract: Comparison of riboflavin-derived flavinium salts applied to catalytic H2O2 oxidations
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Mild synthesis of silyl ethers via potassium carbonate catalyzed reactions between alcohols and hydrosilanes

A method has been developed for the silanolysis of alcohols using an abundant and non-corrosive base K2CO3 as a catalyst.

Graphical abstract: Mild synthesis of silyl ethers via potassium carbonate catalyzed reactions between alcohols and hydrosilanes
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Dynamic kinetic resolution of biaryl atropisomers by chiral dialkylaminopyridine catalysts

Dynamic kinetic resolutions of atropisomers using chiral DMAPs with fluxional chirality.

Graphical abstract: Dynamic kinetic resolution of biaryl atropisomers by chiral dialkylaminopyridine catalysts
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Rhodium(III)-catalyzed CF3-carbenoid C–H functionalization of 6-arylpurines

An expedient route to access a new family of fluorine-containing purine derivatives via chelation-controlled rhodium(III)-catalyzed carbenoid C–H functionalization has been developed.

Graphical abstract: Rhodium(iii)-catalyzed CF3-carbenoid C–H functionalization of 6-arylpurines
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Enantioselective addition of selenosulfonates to α,β-unsaturated ketones

An efficient organo-catalyzed enantioselective addition of selenosulfonates to α,β-unsaturated ketones was developed for the first time.

Graphical abstract: Enantioselective addition of selenosulfonates to α,β-unsaturated ketones
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Highly efficient hydroboration of carbonyl compounds catalyzed by tris(methylcyclopentadienyl)lanthanide complexes

(MeCp)3Ln complexes are reported as highly efficient catalysts in promoting hydroboration and a plausible stepwise mechanism is proposed.

Graphical abstract: Highly efficient hydroboration of carbonyl compounds catalyzed by tris(methylcyclopentadienyl)lanthanide complexes
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Switching glycosyltransferase UGTBL1 regioselectivity toward polydatin synthesis using a semi-rational design

Conduct structure-guided modification on the “hotspot” of glycosyltransferase UGTBL1 to significantly adjust its regioselectivity toward polydatin production.

Graphical abstract: Switching glycosyltransferase UGTBL1 regioselectivity toward polydatin synthesis using a semi-rational design
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Synthesis and application of a new hexamethyl-1,1′-spirobiindane-based chiral bisphosphine (HMSI-PHOS) ligand in asymmetric allylic alkylation

A new class of hexamethyl-1,1′-spirobiindane-based chiral bisphosphine ligand was synthesized and used in Pd-catalyzed asymmetric allylic alkylation reactions.

Graphical abstract: Synthesis and application of a new hexamethyl-1,1′-spirobiindane-based chiral bisphosphine (HMSI-PHOS) ligand in asymmetric allylic alkylation
From the themed collection: Catalysis & biocatalysis in OBC
Paper

New chiral amino alcohol ligands for catalytic enantioselective addition of diethylzincs to aldehydes

New amino alcohol ligands suitable for immobilization on nanoparticles were successfully used in catalytic enantioselective additions of diethylzinc to aldehydes.

Graphical abstract: New chiral amino alcohol ligands for catalytic enantioselective addition of diethylzincs to aldehydes
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Planar chiral [2.2]paracyclophane-based phosphine–phenols: use in enantioselective [3 + 2] annulations of allenoates and N-tosylimines

Planar chiral [2.2]paracyclophane-based phosphine–phenols efficiently catalyze the [3 + 2] annulation of N-tosylimines and allenoate.

Graphical abstract: Planar chiral [2.2]paracyclophane-based phosphine–phenols: use in enantioselective [3 + 2] annulations of allenoates and N-tosylimines
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Organocatalytic asymmetric Michael/hemiacetalization/acyl transfer reaction of α-nitroketones with o-hydroxycinnamaldehydes: synthesis of 2,4-disubstituted chromans

An organocatalytic asymmetric synthesis of 2,4-disubstituted chroman compounds has been developed via a Michael/hemiketalization/acyl transfer reaction between o-hydroxycinnamaldehydes and α-nitroketones.

Graphical abstract: Organocatalytic asymmetric Michael/hemiacetalization/acyl transfer reaction of α-nitroketones with o-hydroxycinnamaldehydes: synthesis of 2,4-disubstituted chromans
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Organocatalytic asymmetric synthesis of benzazepinoindole derivatives with trifluoromethylated quaternary stereocenters by chiral phosphoric acid catalysts

An enantioselective aza-Friedel–Crafts reaction of trifluoromethyl dihydrobenzoazepinoindoles with pyrroles or indoles catalyzed by a chiral spirocyclic phosphoric acid was developed.

Graphical abstract: Organocatalytic asymmetric synthesis of benzazepinoindole derivatives with trifluoromethylated quaternary stereocenters by chiral phosphoric acid catalysts
From the themed collection: Catalysis & biocatalysis in OBC
Paper

A regiospecific rhamnosyltransferase from Epimedium pseudowushanense catalyzes the 3-O-rhamnosylation of prenylflavonols

A novel rhamnosyltransferase and a UDP-rhamnose synthase were characterized and applied to the biosynthesis of bioactive prenylflavonol rhamnosides.

Graphical abstract: A regiospecific rhamnosyltransferase from Epimedium pseudowushanense catalyzes the 3-O-rhamnosylation of prenylflavonols
From the themed collection: Catalysis & biocatalysis in OBC
Paper

Gold catalyzed Heck-coupling of arenediazonium o-benzenedisulfonimides

An efficient gold catalyzed Heck coupling of arenediazonium o-benzenedisulfonimides is proposed. An o-benzenedisulfonimide anion enables a radical pathway that does not require the presence of photocatalysts or external oxidants.

Graphical abstract: Gold catalyzed Heck-coupling of arenediazonium o-benzenedisulfonimides
From the themed collection: Catalysis & biocatalysis in OBC
Paper

A nickel catalyzed acceptorless dehydrogenative approach to quinolines

A general, efficient and environmentally benign, one-step synthesis of substituted quinoline derivatives was achieved by acceptorless dehydrogenative coupling of o-aminobenzylalcohols with ketones and secondary alcohols catalyzed by a cheap, earth abundant and easy to prepare macrocyclic nickel catalyst [Ni(MeTAA)].

Graphical abstract: A nickel catalyzed acceptorless dehydrogenative approach to quinolines
From the themed collection: Catalysis & biocatalysis in OBC
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The latest articles published in Organic and Biomolecular Chemistry related to catalysis and biocatalysis research.

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