Ionic liquid cations as methylation agent for extremely weak chalcogenido metalate nucleophiles
Imidazolium-based ionic liquids served to selectively methylate terminal chalcogenide ligands of chalcogenidometalate clusters [Sn10S16O4(SMe)4]4−, [Mn4Sn4Se13(SeMe)4]6−, and [Hg6Te10(TeMe)2]6−.
Enantioseparation by crystallization using magnetic substrates
Enantiospecific crystallization of the three amino acids asparagine (Asn), glutamic acid hydrochloride (Glu·HCl) and threonine (Thr), induced by ferromagnetic (FM) substrates, is reported.
Mapping binary copolymer property space with neural networks
We map the property space of binary copolymers to understand how copolymerisation can be used to tune the optoelectronic properties of polymers.
A sulfonium tethered peptide ligand rapidly and selectively modifies protein cysteine in vicinity
A unique peptide stabilization method provides a tethered sulfonium that can rapidly and selectively modify protein cysteine in close vicinity.
Synthesis of sterically hindered 4,5-diarylphenanthrenes via acid-catalyzed bisannulation of benzenediacetaldehydes with alkynes
Acid-catalyzed bisannulation of benzenediacetaldehydes with alkynes provided a rapid access to sterically hindered 4,5-diarylphenanthrenes and multisubstituted phenanthrenes regioselectively.
Targeting triple-negative breast cancer cells using Dengue virus-mimicking pH-responsive framboidal triblock copolymer vesicles
Dengue fever-mimicking pH-responsive framboidal triblock copolymer vesicles enable delivery of a nucleic acid payload to the nuclei of triple-negative breast cancer cells.
Aqueous acid-based synthesis of lead-free tin halide perovskites with near-unity photoluminescence quantum efficiency
Aqueous acid-based synthesis of lead-free tin halide perovskites with near-unity photoluminescence quantum efficiency and high chemical yield is described.
Carbon monoxide insertion at a heavy p-block element: unprecedented formation of a cationic bismuth carbamoyl
The first insertion reaction of CO with a molecular complex of the heavy p-block elements is reported (principal quantum number > 4).
Controlling a burn: outer-sphere gating of hydroxylamine oxidation by a distal base in cytochrome P460
One amino acid makes the difference between a metalloenzyme and a metalloprotein in two otherwise effectively identical cytochrome P460s.
Chiral phosphoric acid-catalyzed enantioselective construction of structurally diverse benzothiazolopyrimidines
Chiral phosphoric acid catalyzed the formal [4+2]-cycloaddition of 2-benzothiazolimines with enecarbamates to provide benzothiazolopyrimidines with up to 99% yield and >99% ee.
ppm Pd-catalyzed, Cu-free Sonogashira couplings in water using commercially available catalyst precursors
A new catalyst that derives from commercially available precursors for copper-free, Pd-catalyzed Sonogashira reactions at the sustainable ppm level of precious metal palladium under mild aqueous micellar conditions has been developed.
Catalytic asymmetric allylation of aldehydes with alkenes through allylic C(sp3)–H functionalization mediated by organophotoredox and chiral chromium hybrid catalysis
We have developed a catalytic asymmetric nucleophilic allylation of aldehydes using simple alkenes as pronucleophiles without relying on stoichiometric metals.
An Al-doped SrTiO3 photocatalyst maintaining sunlight-driven overall water splitting activity for over 1000 h of constant illumination
The development of robust and efficient water splitting photocatalysts overcomes a long-standing barrier to sustainable large-scale solar hydrogen evolution systems.
A molecular picture of surface interactions of organic compounds on prevalent indoor surfaces: limonene adsorption on SiO2
Integration of experiment, theory and modeling to understand the interaction type and kinetics of limonene on silica surfaces.
Influence of intramolecular secondary sphere hydrogen-bonding interactions on cytochrome c oxidase inspired low-spin heme–peroxo–copper complexes
Structural/electronic influence of metalloenzyme-inspired synthetic heme–peroxo–copper models containing intramolecular hydrogen bonding interactions.
Hollow nanoreactors for Pd-catalyzed Suzuki–Miyaura coupling and O-propargyl cleavage reactions in bio-relevant aqueous media
We describe the fabrication of hollow microspheres consisting of mesoporous silica nanoshells decorated with an inner layer of palladium nanoparticles and their use as Pd-nanoreactors in aqueous media.
An integrated-molecular-beacon based multiple exponential strand displacement amplification strategy for ultrasensitive detection of DNA methyltransferase activity
An ultra-sensitive biosensor using only two DNA oligos to initiate multiple signal amplification cycles.
Waterproof architectures through subcomponent self-assembly
Construction of metal–organic containers that are soluble and stable in water can be challenging – we present diverse strategies that allow the synthesis of kinetically robust water-soluble architectures via subcomponent self-assembly.
About this collection
In 2018, the Chemical Science Editorial Team launched ‘ChemSci Pick of the Week’ as a means to select and promote our favourite articles from the week and share them with the wider chemical community. This on-going web collection showcases all ChemSci Picks from 2019.