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Themed collection Graphene Turns 15: Bio-implications and Bio-applications

36 items
Minireview

Graphene oxide and carbon dots as broad-spectrum antimicrobial agents – a minireview

Complex antibacterial mechanisms of graphene oxide and carbon dots.

Graphical abstract: Graphene oxide and carbon dots as broad-spectrum antimicrobial agents – a minireview
From the themed collection: Recent Review Articles
Review Article

Graphene oxide touches blood: in vivo interactions of bio-coronated 2D materials

The impact of graphene oxide biomolecular corona on blood components.

Graphical abstract: Graphene oxide touches blood: in vivo interactions of bio-coronated 2D materials
From the themed collection: Recent Review Articles
Open Access Review Article

Occupational exposure to graphene based nanomaterials: risk assessment

The most significant routes associated with occupational exposure to graphene-based materials (GBMs) are the inhalation, cutaneous, ocular and oral ones. The manuscript presents a review of the in vivo toxicity data of GBMs after these exposure routes.

Graphical abstract: Occupational exposure to graphene based nanomaterials: risk assessment
From the themed collection: Recent Open Access Articles
Review Article

Three-dimensional graphene-based polymer nanocomposites: preparation, properties and applications

A schematic illustration of the fabrication strategies and applications of 3D-GPNCs is shown.

Graphical abstract: Three-dimensional graphene-based polymer nanocomposites: preparation, properties and applications
From the themed collection: Recent Review Articles
Review Article

Stability, transport and ecosystem effects of graphene in water and soil environments

Graphene nanomaterials (GMs), such as graphene oxide (GO) and reduced graphene oxide (rGO), have been widely applied in various fields.

Graphical abstract: Stability, transport and ecosystem effects of graphene in water and soil environments
Review Article

Graphene and its derivatives as versatile templates for materials synthesis and functional applications

Recent progress in the use of graphene and its derivatives as versatile templates for materials synthesis and functional applications has been elaborately demonstrated, and perspectives on potential future challenges and opportunities in this research area are discussed.

Graphical abstract: Graphene and its derivatives as versatile templates for materials synthesis and functional applications
Open Access Review Article

Science and technology roadmap for graphene, related two-dimensional crystals, and hybrid systems

We present the science and technology roadmap for graphene, related two-dimensional crystals, and hybrid systems, targeting an evolution in technology, that might lead to impacts and benefits reaching into most areas of society.

Graphical abstract: Science and technology roadmap for graphene, related two-dimensional crystals, and hybrid systems
Communication

Graphene–silicon-on-insulator (GSOI) Schottky diode photodetectors

Graphene–silicon-on-insulator (GSOI) photodetectors for high-speed free space light detection.

Graphical abstract: Graphene–silicon-on-insulator (GSOI) Schottky diode photodetectors
Communication

Graphene integrated circuits: new prospects towards receiver realisation

This work demonstrates a design approach which enables the fabrication of fully integrated radio frequency (RF) and millimetre-wave frequency direct-conversion graphene receivers by adapting the frontend architecture to exploit the state-of-the-art performance of the recently reported wafer-scale CVD metal–insulator–graphene (MIG) diodes.

Graphical abstract: Graphene integrated circuits: new prospects towards receiver realisation
Communication

A novel artificial synapse with dual modes using bilayer graphene as the bottom electrode

We report a single device operated in two modes with enough potentiation states to mimic the synaptic learning behaviors.

Graphical abstract: A novel artificial synapse with dual modes using bilayer graphene as the bottom electrode
Communication

Laser-patterned functionalized CVD-graphene as highly transparent conductive electrodes for polymer solar cells

Polymer solar cells with an efficiency of 4.2% have been fabricated on properly functionalized and laser-patterned CVD-graphene used as electrode.

Graphical abstract: Laser-patterned functionalized CVD-graphene as highly transparent conductive electrodes for polymer solar cells
Paper

Graphene-based neuron encapsulation with controlled axonal outgrowth

We demonstrate the formation of a micro-roll for neuron encapsulation with a self-folding graphene/parylene-C bilayer film, and show the importance of using pores on the micro-roll to allow the encapsulated neurons to interact with the surroundings.

Graphical abstract: Graphene-based neuron encapsulation with controlled axonal outgrowth
From the themed collection: Nanocarbons
Paper

Few layer graphene does not affect the function and the autophagic activity of primary lymphocytes

Primary lymphocytes ensure their efficient function and maintenance through different mechanisms including autophagy. Few layer graphene does not affect either the viability and activation or the autophagic activity of B and T cells.

Graphical abstract: Few layer graphene does not affect the function and the autophagic activity of primary lymphocytes
Open Access Paper

Spatio-temporal dynamics in graphene

The dynamics of optically excited carriers in graphene is resolved in time, momentum and space revealing the interplay of diffusion and scattering processes.

Graphical abstract: Spatio-temporal dynamics in graphene
From the themed collection: Recent Open Access Articles
Open Access Paper

Graphene oxide prevents mycobacteria entry into macrophages through extracellular entrapment

GO trapping reduces mycobacteria entry in macrophages when the bacilli are in the external environment: a possible therapeutic strategy for tuberculosis.

Graphical abstract: Graphene oxide prevents mycobacteria entry into macrophages through extracellular entrapment
Open Access Paper

Graphene–Si CMOS oscillators

The ambipolarity of graphene is exploited to realize a new class of electronic oscillators by integrating a graphene field-effect transistor with Si CMOS logic.

Graphical abstract: Graphene–Si CMOS oscillators
From the themed collection: Recent Open Access Articles
Open Access Paper

Multi-layer graphene as a selective detector for future lung cancer biosensing platforms

Multilayer graphene can be used to detect volatile organic compounds, with enhanced selectivity and sensitivity through surface patterning.

Graphical abstract: Multi-layer graphene as a selective detector for future lung cancer biosensing platforms
From the themed collection: Recent Open Access Articles
Paper

A silicon nitride waveguide-integrated chemical vapor deposited graphene photodetector with 38 GHz bandwidth

We demonstrate a high-speed chemical vapor deposited graphene-on-silicon nitride waveguide photodetector.

Graphical abstract: A silicon nitride waveguide-integrated chemical vapor deposited graphene photodetector with 38 GHz bandwidth
Paper

Peroxidase mimicking DNAzymes degrade graphene oxide

A DNAzyme made of guanine-rich DNA and hemin is capable of degrading graphene oxide sheets in the presence of hydrogen peroxide similarly to the natural enzyme horseradish peroxidase.

Graphical abstract: Peroxidase mimicking DNAzymes degrade graphene oxide
Paper

Graphene aerogels that withstand extreme compressive stress and strain

The superelastic aerogels can withstand a loading of 100 000 N for 60 min and retain their substantial elastic resilience. This loading corresponds to an ultimate compressive stress of approximately 1000 MPa and a strain of 99.8%.

Graphical abstract: Graphene aerogels that withstand extreme compressive stress and strain
Paper

Stokes and anti-Stokes Raman scattering in mono- and bilayer graphene

The 2D mode of graphene exhibits significant frequency discrepancies between its Stokes and anti-Stokes components, making it possible to probe the nonlinear phonon dispersion of the iTO branch near K.

Graphical abstract: Stokes and anti-Stokes Raman scattering in mono- and bilayer graphene
Open Access Paper

Graphene and graphene oxide induce ROS production in human HaCaT skin keratinocytes: the role of xanthine oxidase and NADH dehydrogenase

Graphene based nanomaterials induce a reactive oxygen species-mediated mitochondrial depolarization, caused by the activation of NADH dehydrogenase and xanthine oxidase.

Graphical abstract: Graphene and graphene oxide induce ROS production in human HaCaT skin keratinocytes: the role of xanthine oxidase and NADH dehydrogenase
From the themed collection: Recent Open Access Articles
Open Access Paper

In vitro and environmental toxicity of reduced graphene oxide as an additive in automotive lubricants

A workflow for evaluation of human and environmental toxicity of nanosized bare graphene material intended as a motorcar lubricant nanoadditive.

Graphical abstract: In vitro and environmental toxicity of reduced graphene oxide as an additive in automotive lubricants
From the themed collection: Recent Open Access Articles
Paper

Graphene-coated polymer foams as tuneable impact sensors

Displaying a strain-dependent electrical response, the porous graphene-based nanocomposite ‘G-foam’ was found to be an effective pressure sensor and sensitive impact-sensing material.

Graphical abstract: Graphene-coated polymer foams as tuneable impact sensors
Paper

Highly stretchable strain sensors with reduced graphene oxide sensing liquids for wearable electronics

Super-elastic strain sensors based on rGO/DI feature impressively high performance and can distinguish between compressive and tensile deformation.

Graphical abstract: Highly stretchable strain sensors with reduced graphene oxide sensing liquids for wearable electronics
Paper

A multifunctional wearable sensor based on a graphene/inverse opal cellulose film for simultaneous, in situ monitoring of human motion and sweat

A multifunctional, wearable sensor based on a rGO/IOAC film has been developed and can perform simultaneous monitoring of human motions and sweat.

Graphical abstract: A multifunctional wearable sensor based on a graphene/inverse opal cellulose film for simultaneous, in situ monitoring of human motion and sweat
Paper

Graphene oxide-mediated Cas9/sgRNA delivery for efficient genome editing

GO-PEG-PEI nanocarrier, which was constructed for the delivery of high-molecular-weight Cas9/sgRNA complexes for executing endocytosis, endosomal escape, nuclear entry, and gene editing.

Graphical abstract: Graphene oxide-mediated Cas9/sgRNA delivery for efficient genome editing
Paper

Graphene oxide is degraded by neutrophils and the degradation products are non-genotoxic

Graphene oxide (GO) undergoes neutrophil myeloperoxidase (MPO) dependent degradation and the degradation products are non-genotoxic for human lung cells.

Graphical abstract: Graphene oxide is degraded by neutrophils and the degradation products are non-genotoxic
Paper

A graphene mesh as a hybrid electrode for foldable devices

A new hybrid electrode for foldable devices based on graphene mesh structures showed extreme flexibility without breakdown after 100 000 cycles.

Graphical abstract: A graphene mesh as a hybrid electrode for foldable devices
Paper

Self-assembled N-graphene nanohollows enabling ultrahigh energy density cathode for Li–S batteries

A novel structure enables Li–S batteries to display large-capacity, high-rate and long-life at an ultra-high areal sulfur loading.

Graphical abstract: Self-assembled N-graphene nanohollows enabling ultrahigh energy density cathode for Li–S batteries
Paper

Functionalized graphene sheets for intracellular controlled release of therapeutic agents

The relationship between the functionalities of graphene-based nanocarriers and their intracellular drug release characteristics was carefully investigated in this paper.

Graphical abstract: Functionalized graphene sheets for intracellular controlled release of therapeutic agents
Paper

A small graphene oxide sheet/polyvinylidene fluoride bilayer actuator with large and rapid responses to multiple stimuli

A high-performance actuator should be able to deliver large-shape deformations, fast actuations and sensitive responses to multiple stimuli.

Graphical abstract: A small graphene oxide sheet/polyvinylidene fluoride bilayer actuator with large and rapid responses to multiple stimuli
Paper

Efficient electro-optic modulation in low-loss graphene-plasmonic slot waveguides

Surface plasmon polaritons enable light concentration within subwavelength regions, and here we demonstrate efficient and compact graphene-plasmonic modulators fully integrated in the silicon-on-insulator platform.

Graphical abstract: Efficient electro-optic modulation in low-loss graphene-plasmonic slot waveguides
Paper

A tactile sensor using single layer graphene for surface texture recognition

A flexible tactile sensor using single layer graphene that can detect surface texture based on a single sensor architecture.

Graphical abstract: A tactile sensor using single layer graphene for surface texture recognition
Paper

pH-Responsive fluorescent graphene quantum dots for fluorescence-guided cancer surgery and diagnosis

Novel pH-responsive fluorescent graphene quantum dots were synthesized for robust and universal solid tumor detection.

Graphical abstract: pH-Responsive fluorescent graphene quantum dots for fluorescence-guided cancer surgery and diagnosis
Paper

Comparison of reduction products from graphite oxide and graphene oxide for anode applications in lithium-ion batteries and sodium-ion batteries

A detailed comparison of the reduction products of graphite oxide and those of graphene oxide for Li+/Na+ storage has been discussed.

Graphical abstract: Comparison of reduction products from graphite oxide and graphene oxide for anode applications in lithium-ion batteries and sodium-ion batteries
36 items

About this collection

To coincide with the 15th year since graphene was first reported, Andrea Ferrari (University of Cambridge and Nanoscale Associate Editor) has picked out his top articles that were recently published in the nanoscale journal family. Focusing specifically on the bio-implications and bio-applications of graphene, this Editor’s Choice collection highlights some of the key recent advances in the field.

Professor Dirk Guldi, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany and Editor-in-chief of Nanoscale and Nanoscale Advances: “The outstanding properties of graphene have been a jump start for cutting-edge research in the areas not only of physics, chemistry, materials science but also of life science.  Hereby, graphene and its 2-dimensional analogues have transcended into a versatile and enabling platform for those multidisciplinary breakthroughs needed to lay the foundation for a myriad of applications.”

Professor Paolo Samori, Université de Strasbourg and Associate Editor for Nanoscale and Nanoscale Advances: “Over the last 15 years, graphene and related materials became the "golden" nanostructures for fundamental studies on their exceptional and physical and chemical properties. The interdisciplinary science of 2D materials has led to major breakthroughs paving the way towards disruptive technologies in opto-electronics, energy, sensing and biomedical applications.”

Andrea Ferrari is also the Science & Technology Officer and Management Panel Chair of the Graphene Flagship, which also celebrated graphene turning 15 this year.

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