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Themed collection Food & Function Recent HOT articles

108 items - Showing page 1 of 2
Open Access Review Article

The effects of polyphenols and other bioactives on human health

Consuming polyphenols is associated with benefits to cardiometabolic health and brain function, which are driven by their complex interrelationship with the gut microbiome, their bioactive metabolites, and other phytochemicals.

Graphical abstract: The effects of polyphenols and other bioactives on human health
From the themed collection: Food & Function Recent HOT articles
Paper

The nanoencapsulation of curcuminoids extracted from Curcuma longa L. and an evaluation of their cytotoxic, enzymatic, antioxidant and anti-inflammatory activities

Curcumin, bisdemethoxycurcumin and demethoxycurcumin are known for their bioactivity.

Graphical abstract: The nanoencapsulation of curcuminoids extracted from Curcuma longa L. and an evaluation of their cytotoxic, enzymatic, antioxidant and anti-inflammatory activities
From the themed collection: Food & Function Recent HOT articles
Paper

Agaricus blazei Murrill from Brazil: an ingredient for nutraceutical and cosmeceutical applications

Agaricus blazei bio-residues were explored as a nutraceutical and cosmaceutical ingredient, by evaluating its effect on cell viability using intestinal and skin cell lines, respectively. A. blazei revealed to be a good ingredient for those applications.

Graphical abstract: Agaricus blazei Murrill from Brazil: an ingredient for nutraceutical and cosmeceutical applications
From the themed collection: Food & Function Recent HOT articles
Paper

Cyanidin inhibits EMT induced by oxaliplatin via targeting the PDK1–PI3K/Akt signaling pathway

Anthocyanins have been shown to exhibit antitumor activity in several cancers in vitro and in vivo.

Graphical abstract: Cyanidin inhibits EMT induced by oxaliplatin via targeting the PDK1–PI3K/Akt signaling pathway
From the themed collection: Food & Function Recent HOT articles
Paper

Lysine-induced swine satellite cell migration is mediated by the FAK pathway

This study demonstrated that the activation of satellite cell migration is dependent on Lysine levels. Furthermore, Lys-dependent satellite cell migration is mediated by the FAK pathway.

Graphical abstract: Lysine-induced swine satellite cell migration is mediated by the FAK pathway
From the themed collection: Food & Function Recent HOT articles
Paper

Biofunctionalization of selenium nanoparticles with a polysaccharide from Rosa roxburghii fruit and their protective effect against H2O2-induced apoptosis in INS-1 cells

The stable selenium nanoparticles (RP3-SeNPs) have a strong protective effect against H2O2-induced apoptosis in INS-1 cells.

Graphical abstract: Biofunctionalization of selenium nanoparticles with a polysaccharide from Rosa roxburghii fruit and their protective effect against H2O2-induced apoptosis in INS-1 cells
From the themed collection: Food & Function Recent HOT articles
Paper

Geographical location specific composition of cultured microbiota and Lactobacillus occurrence in human breast milk in China

Composition of microbiota in human breast milk in China was highly geographical location specific and can be classified into Enterococcus, Streptococcus and Staphylococcus dominant group, respectively. The occurrence rate of Lactobacillus in Northwest and North China is high. Lactobacillus reuteri and Lactobacillus gasseri in Tibetan samples, Gansu Lintan, were the highest.

Graphical abstract: Geographical location specific composition of cultured microbiota and Lactobacillus occurrence in human breast milk in China
From the themed collection: Food & Function Recent HOT articles
Paper

Dietary wild bitter gourd displays selective androgen receptor modulator like activity and improves the muscle decline of orchidectomized mice

Wild bitter gourd, like selective androgen receptor modulators (SARMs), restored the mass of androgen responsive muscles but not prostate and might improve skeletal muscle function in orchidectomized mice.

Graphical abstract: Dietary wild bitter gourd displays selective androgen receptor modulator like activity and improves the muscle decline of orchidectomized mice
From the themed collection: Food & Function Recent HOT articles
Paper

Effect of the food form and structure on lipid digestion and postprandial lipaemic response

As the food matrix is a determinant of the rate of fat digestion and absorption, it is important for the modulation of postprandial triglyceridaemia.

Graphical abstract: Effect of the food form and structure on lipid digestion and postprandial lipaemic response
From the themed collection: Food & Function Recent HOT articles
Paper

Anti-melanogenesis properties of condensed tannins from Vigna angularis seeds with potent antioxidant and DNA damage protection activities

The characterization, anti-tyrosinase activity, cytotoxicity against B16 mouse melanoma cells, antioxidant, and DNA damage protection activities of condensed tannins purified from Vigna angularis seeds were reported.

Graphical abstract: Anti-melanogenesis properties of condensed tannins from Vigna angularis seeds with potent antioxidant and DNA damage protection activities
From the themed collection: Food & Function Recent HOT articles
Paper

Evaluation of the bitter components of bamboo shoots using a metabolomics approach

The metabolomics methodology can be more convenient to evaluate the function of food.

Graphical abstract: Evaluation of the bitter components of bamboo shoots using a metabolomics approach
From the themed collection: Food & Function Recent HOT articles
Paper

Calluna vulgaris (L.) Hull: chemical characterization, evaluation of its bioactive properties and effect on the vaginal microbiota

C. vulgaris inflorescences revealed myricetin derivatives as the main compound and polar extracts revealed higher bioactivities, preserving vaginal microbiota.

Graphical abstract: Calluna vulgaris (L.) Hull: chemical characterization, evaluation of its bioactive properties and effect on the vaginal microbiota
From the themed collection: Food & Function Recent HOT articles
Paper

Dietary methionine restriction reduces hepatic steatosis and oxidative stress in high-fat-fed mice by promoting H2S production

Dietary methionine restriction reduces hepatic steatosis and oxidative stress in high-fat-fed mice by promoting H2S production.

Graphical abstract: Dietary methionine restriction reduces hepatic steatosis and oxidative stress in high-fat-fed mice by promoting H2S production
From the themed collection: Food & Function Recent HOT articles
Paper

Algal oil rich in n-3 polyunsaturated fatty acids suppresses B16F10 melanoma lung metastasis by autophagy induction

Melanoma is a malignant tumor that arises from epidermal melanocytes with high morbidity and mortality, and currently, there are no effective conventional genotoxic treatments or systematic treatment.

Graphical abstract: Algal oil rich in n-3 polyunsaturated fatty acids suppresses B16F10 melanoma lung metastasis by autophagy induction
From the themed collection: Food & Function Recent HOT articles
Paper

Spirulina platensis and silicon-enriched spirulina equally improve glucose tolerance and decrease the enzymatic activity of hepatic NADPH oxidase in obesogenic diet-fed rats

The prevalence of metabolic syndrome components, such as obesity, glucose intolerance and hepatic steatosis, is rapidly increasing and becoming a major issue of public health.

Graphical abstract: Spirulina platensis and silicon-enriched spirulina equally improve glucose tolerance and decrease the enzymatic activity of hepatic NADPH oxidase in obesogenic diet-fed rats
From the themed collection: Food & Function Recent HOT articles
Paper

The antifungal activity of extracts of Osmundea pinnatifida, an edible seaweed, indicates its usage as a safe environmental fungicide or as a food additive preventing post-harvest fungal food contamination

Extracts of the edible seaweed Osmundea pinnatifida impair Aspergillus fumigatus and Alternaria infectoria conidiation.

Graphical abstract: The antifungal activity of extracts of Osmundea pinnatifida, an edible seaweed, indicates its usage as a safe environmental fungicide or as a food additive preventing post-harvest fungal food contamination
From the themed collection: Food & Function Recent HOT articles
Paper

Enhancing the antimicrobial and antifungal activities of a coloring extract agent rich in betacyanins obtained from Gomphrena globosa L. flowers

Gomphrena globosa flower extracts were optimized to achieve high antimicrobial and antifungal activities: 10.8 min, 410.5 W, 57.8% of ethanol, and 5 g L−1 solid–liquid ratio.

Graphical abstract: Enhancing the antimicrobial and antifungal activities of a coloring extract agent rich in betacyanins obtained from Gomphrena globosa L. flowers
From the themed collection: Food & Function Recent HOT articles
Paper

Licochalcone A inhibits the invasive potential of human glioma cells by targeting the MEK/ERK and ADAM9 signaling pathways

Licochalcone A (LicA) has been reported to possess antitumor properties.

Graphical abstract: Licochalcone A inhibits the invasive potential of human glioma cells by targeting the MEK/ERK and ADAM9 signaling pathways
From the themed collection: Food & Function Recent HOT articles
Paper

Chlorogenic acid methyl ester exerts strong anti-inflammatory effects via inhibiting the COX-2/NLRP3/NF-κB pathway

In vivo and in vitro studies show that chlorogenic acid methyl ester (CME) has been proven to be a potential nutraceutical for preventing inflammation.

Graphical abstract: Chlorogenic acid methyl ester exerts strong anti-inflammatory effects via inhibiting the COX-2/NLRP3/NF-κB pathway
From the themed collection: Food & Function Recent HOT articles
Open Access Paper

Deoxycholic acid disrupts the intestinal mucosal barrier and promotes intestinal tumorigenesis

Deoxycholic acid (DCA) induced intestinal low grade inflammation and disrupted the mucosal physical and functional barriers, aggravating intestinal tumorigenesis.

Graphical abstract: Deoxycholic acid disrupts the intestinal mucosal barrier and promotes intestinal tumorigenesis
From the themed collection: Food & Function Recent HOT articles
Paper

Oleogel-structured composite for the stabilization of ω3 fatty acids in fish oil

The fish oil is encapsulated in a multi-compartment system featuring β-cyclodextrin complexation within whey protein isolate (WPI) coated oleogel particles.

Graphical abstract: Oleogel-structured composite for the stabilization of ω3 fatty acids in fish oil
From the themed collection: Food & Function Recent HOT articles
Paper

The solvation properties and effect of D-fructose on the taste behavior of Citrus aurantium active components in aqueous solutions

The densities and viscosities of synephrine hydrochloride and octopamine hydrochloride aqueous solutions were determined.

Graphical abstract: The solvation properties and effect of d-fructose on the taste behavior of Citrus aurantium active components in aqueous solutions
From the themed collection: Food & Function Recent HOT articles
Paper

Transcriptome analysis reveals the mechanism of the effect of flower tea Coreopsis tinctoria on hepatic insulin resistance

Non-Camellia tea and herbal medicine help prevent the development of diabetes and other metabolic diseases.

Graphical abstract: Transcriptome analysis reveals the mechanism of the effect of flower tea Coreopsis tinctoria on hepatic insulin resistance
From the themed collection: Food & Function Recent HOT articles
Paper

Potential of iturins as functional agents: safe, probiotic, and cytotoxic to cancer cells

Iturins are safe for oral administration, increase the abundance of probiotics, and reduce fat intake by regulating the intestinal microflora.

Graphical abstract: Potential of iturins as functional agents: safe, probiotic, and cytotoxic to cancer cells
From the themed collection: Food & Function Recent HOT articles
Paper

Characterization of transglutaminase from Bacillus subtilis and its cross-linking function with a bovine serum albumin model

The functional properties of bovine serum albumin were significantly improved by Bacillus subtilis transglutaminase with good thermal and pH stability.

Graphical abstract: Characterization of transglutaminase from Bacillus subtilis and its cross-linking function with a bovine serum albumin model
From the themed collection: Food & Function Recent HOT articles
Paper

Bioactive properties and phytochemical assessment of Bacupari-anão (Garcinia brasiliensis Mart.) leaves native to Rondônia, Brazil

Extracts of Garcinia brasiliensis Mart. revealed health promoting biological properties.

Graphical abstract: Bioactive properties and phytochemical assessment of Bacupari-anão (Garcinia brasiliensis Mart.) leaves native to Rondônia, Brazil
From the themed collection: Food & Function Recent HOT articles
Paper

Tannic acid directly targets pyruvate kinase isoenzyme M2 to attenuate colon cancer cell proliferation

Tannic acid, which ubiquitously exists in grapes and green tea, binds to K433 to trigger dissociation of PKM2 tetramers and further block the metabolic activity of PKM2 to suppress colorectal cancer cell proliferation.

Graphical abstract: Tannic acid directly targets pyruvate kinase isoenzyme M2 to attenuate colon cancer cell proliferation
From the themed collection: Food & Function Recent HOT articles
Paper

Coloured rice-derived polyphenols reduce lipid peroxidation and pro-inflammatory cytokines ex vivo

Coloured rice-derived polyphenols demonstrate potential at reducing biomarkers associated with lipid peroxidation and inflammation.

Graphical abstract: Coloured rice-derived polyphenols reduce lipid peroxidation and pro-inflammatory cytokines ex vivo
From the themed collection: Food & Function Recent HOT articles
Paper

Screening for active constituents in Turkish galls against ulcerative colitis by mass spectrometry guided preparative chromatography strategy: in silico, in vitro and in vivo study

Screening for active constituents in Turkish galls against ulcerative colitis by mass spectrometry guided preparative chromatography strategy: in silico, in vitro and in vivo study.

Graphical abstract: Screening for active constituents in Turkish galls against ulcerative colitis by mass spectrometry guided preparative chromatography strategy: in silico, in vitro and in vivo study
From the themed collection: Food & Function Recent HOT articles
Paper

Roasting improves the hypoglycemic effects of a large-leaf yellow tea infusion by enhancing the levels of epimerized catechins that inhibit α-glucosidase

Teas contain bioactive polyphenols, such as (−)-epigallocatechin gallate (EGCG), which is not stable during the processing of tea.

Graphical abstract: Roasting improves the hypoglycemic effects of a large-leaf yellow tea infusion by enhancing the levels of epimerized catechins that inhibit α-glucosidase
From the themed collection: Food & Function Recent HOT articles
Paper

Narrow-leafed lupin (Lupinus angustifolius L.) seed β-conglutins reverse the induced insulin resistance in pancreatic cells

Narrow-leafed lupin β-conglutin proteins may help to prevent and treat insulin resistance through pleiotropic effects.

Graphical abstract: Narrow-leafed lupin (Lupinus angustifolius L.) seed β-conglutins reverse the induced insulin resistance in pancreatic cells
From the themed collection: Food & Function Recent HOT articles
Paper

Changes in the metabolite profile of breast milk over lactation stages and their relationship with dietary intake in Chinese women: HPLC-QTOFMS based metabolomic analysis

The metabolite profile of breast milk changes over lactation stages in Chinese women, independent of dietary intake.

Graphical abstract: Changes in the metabolite profile of breast milk over lactation stages and their relationship with dietary intake in Chinese women: HPLC-QTOFMS based metabolomic analysis
From the themed collection: Food & Function Recent HOT articles
Paper

Effects of gamma radiation on the bioactivity of medicinal and aromatic plants: Mentha × piperita L., Thymus vulgaris L. and Aloysia citrodora Paláu as case studies

Cytotoxicity, virucidal and phenolic compounds presented differences among the irradiated samples, while antimicrobial activity was not affected.

Graphical abstract: Effects of gamma radiation on the bioactivity of medicinal and aromatic plants: Mentha × piperita L., Thymus vulgaris L. and Aloysia citrodora Paláu as case studies
From the themed collection: Food & Function Recent HOT articles
Paper

Complete digestion of edible bird's nest releases free N-acetylneuraminic acid and small peptides: an efficient method to improve functional properties

Digestion is an effective strategy to improve the functional properties (skin whitening and osteogenic effect) of edible bird's nest.

Graphical abstract: Complete digestion of edible bird's nest releases free N-acetylneuraminic acid and small peptides: an efficient method to improve functional properties
From the themed collection: Food & Function Recent HOT articles
Paper

Proanthocyanidin B2 attenuates postprandial blood glucose and its inhibitory effect on alpha-glucosidase: analysis by kinetics, fluorescence spectroscopy, atomic force microscopy and molecular docking

As a dimer of proanthocyanidin, proanthocyanidin B2 (PB2) was found to effectively attenuate postprandial blood glucose in mice after sucrose loading.

Graphical abstract: Proanthocyanidin B2 attenuates postprandial blood glucose and its inhibitory effect on alpha-glucosidase: analysis by kinetics, fluorescence spectroscopy, atomic force microscopy and molecular docking
From the themed collection: Food & Function Recent HOT articles
Paper

Phenolic profile and in vitro bioactive potential of Saharan Juniperus phoenicea L. and Cotula cinerea (Del) growing in Algeria

Juniperus phoenicea presented 3-p-coumaroylquinic acid as the main compound, while Cotula cinerea contained luteolin derivatives and 5-O-caffeoylquinic acid. The hydroethanolic extracts showed the highest bioactivities.

Graphical abstract: Phenolic profile and in vitro bioactive potential of Saharan Juniperus phoenicea L. and Cotula cinerea (Del) growing in Algeria
From the themed collection: Food & Function Recent HOT articles
Paper

Enzymatic digest of whey protein and wheylin-1, a dipeptide released in the digest, increase insulin sensitivity in an Akt phosphorylation-dependent manner

Wheylin-1 is the first whey-derived peptide that increases insulin sensitivity in an Akt phosphorylation-dependent manner and lowers blood glucose levels.

Graphical abstract: Enzymatic digest of whey protein and wheylin-1, a dipeptide released in the digest, increase insulin sensitivity in an Akt phosphorylation-dependent manner
From the themed collection: Food & Function Recent HOT articles
Paper

(−)-Epigallocatechin-3-gallate (EGCG) inhibits starch digestion and improves glucose homeostasis through direct or indirect activation of PXR/CAR-mediated phase II metabolism in diabetic mice

As a major component of green tea, (−)-epigallocatechin-3-gallate (EGCG) has attracted interest from scientists owing to its potential to combat a variety of human diseases including abnormal glucose metabolism in obesity and diabetes.

Graphical abstract: (−)-Epigallocatechin-3-gallate (EGCG) inhibits starch digestion and improves glucose homeostasis through direct or indirect activation of PXR/CAR-mediated phase II metabolism in diabetic mice
From the themed collection: Food & Function Recent HOT articles
Paper

Application of a commercial digestive supplement formulated with enzymes and probiotics in lactase non-persistence management

Strategies to avoid lactose malabsorption, which affects 70% of the world's population, are focused on the restriction of milk and dairy products or the use of non-human β-galactosidases or probiotics endowed with β-galactosidase activity added at mealtime.

Graphical abstract: Application of a commercial digestive supplement formulated with enzymes and probiotics in lactase non-persistence management
From the themed collection: Food & Function Recent HOT articles
Paper

Crystallisation of freeze-dried sucrose in model mixtures that represent the amorphous sugar matrices present in confectionery

Sucrose crystallization is highly dependent on the presence of other common food ingredients within an amorphous freeze-dried matrix.

Graphical abstract: Crystallisation of freeze-dried sucrose in model mixtures that represent the amorphous sugar matrices present in confectionery
From the themed collection: Food & Function Recent HOT articles
Paper

Storage conditions modulate the metabolomic profile of a black raspberry nectar with minimal impact on bioactivity

Untargeted UHPLC-Q-TOF-MS metabolomics demonstrated large chemical variation was introduced by storage, though minimal change in anti-proliferative activity of these stored extracts to premalignant oral epithelial cells was observed.

Graphical abstract: Storage conditions modulate the metabolomic profile of a black raspberry nectar with minimal impact on bioactivity
From the themed collection: Food & Function Recent HOT articles
Paper

Long-term effects of lysine concentration on growth performance, intestinal microbiome, and metabolic profiles in a pig model

Lysine is a common limiting amino acid in human and animal diets and plays an important role in cell proliferation and metabolism.

Graphical abstract: Long-term effects of lysine concentration on growth performance, intestinal microbiome, and metabolic profiles in a pig model
From the themed collection: Food & Function Recent HOT articles
Paper

Major compounds of red ginseng oil attenuate Aβ25–35-induced neuronal apoptosis and inflammation by modulating MAPK/NF-κB pathway

The present study suggests that the major compounds of red ginseng oil prevent Aβ-induced neurotoxicity via anti-apoptotic and anti-inflammatory functions.

Graphical abstract: Major compounds of red ginseng oil attenuate Aβ25–35-induced neuronal apoptosis and inflammation by modulating MAPK/NF-κB pathway
From the themed collection: Food & Function Recent HOT articles
Paper

Effects of dietary tryptophan supplementation in the acetic acid-induced colitis mouse model

Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the gastrointestinal tract and is strongly associated with intestinal immunity and the microbiome.

Graphical abstract: Effects of dietary tryptophan supplementation in the acetic acid-induced colitis mouse model
From the themed collection: Food & Function Recent HOT articles
Paper

Preparation of a fermentation solution of grass fish bones and its calcium bioavailability in rats

In this study, with grass fish bones as the substrate, after flavourzyme treatment, and fermentation with Leuconostoc mesenteroides, a fermentation solution with a high content of soluble calcium was obtained.

Graphical abstract: Preparation of a fermentation solution of grass fish bones and its calcium bioavailability in rats
From the themed collection: Food & Function Recent HOT articles
Paper

The epithelial barrier-protecting properties of a soy hydrolysate

A soy hydrolysate protects the epithelial cell layer from an increase in permeability in a barrier disruptor specific manner.

Graphical abstract: The epithelial barrier-protecting properties of a soy hydrolysate
From the themed collection: Food & Function Recent HOT articles
Paper

Preclinical safety evaluation of the ethanolic extract from Campomanesia pubescens (Mart. ex DC.) O.BERG (guavira) fruits: analysis of genotoxicity and clastogenic effects

Genotoxicity studies of medicinal plants are recommended by international regulatory agencies as part of the risk assessment.

Graphical abstract: Preclinical safety evaluation of the ethanolic extract from Campomanesia pubescens (Mart. ex DC.) O.BERG (guavira) fruits: analysis of genotoxicity and clastogenic effects
From the themed collection: Food & Function Recent HOT articles
Paper

Dietary methionine restriction regulated energy and protein homeostasis by improving thyroid function in high fat diet mice

Dietary methionine restriction regulated energy and protein homeostasis by improving thyroid function in high fat diet mice.

Graphical abstract: Dietary methionine restriction regulated energy and protein homeostasis by improving thyroid function in high fat diet mice
From the themed collection: Food & Function Recent HOT articles
Paper

Ellagic acid–borax fluorescence interaction: application for novel cyclodextrin-borax nanosensors for analyzing ellagic acid in food samples

The food industry needs cheap, fast and sensitive methods. For that reason, the Ellagic acid–Borax–Cyclodextrin complex fluorescence enhancing has been studied.

Graphical abstract: Ellagic acid–borax fluorescence interaction: application for novel cyclodextrin-borax nanosensors for analyzing ellagic acid in food samples
From the themed collection: Food & Function Recent HOT articles
Paper

Nanodispersions of beta-carotene: effects on antioxidant enzymes and cytotoxic properties

Beta-carotene is a carotenoid precursor of vitamin A, known for its biological activities.

Graphical abstract: Nanodispersions of beta-carotene: effects on antioxidant enzymes and cytotoxic properties
From the themed collection: Food & Function Recent HOT articles
Paper

Strain-specific properties of Lactobacillus plantarum for prevention of Salmonella infection

Lactobacillus plantarum have strain-specific properties towards prevention of Salmonella infection.

Graphical abstract: Strain-specific properties of Lactobacillus plantarum for prevention of Salmonella infection
From the themed collection: Food & Function Recent HOT articles
Paper

Evaluation of biological and antimicrobial properties of freeze-dried whey fermented by different strains of Lactobacillus plantarum

The aim of this study was to evaluate the biological and antimicrobial activities of commercial freeze-dried whey fermented by lactic acid bacteria in order to valorize this high polluting liquid waste of the dairy industry.

Graphical abstract: Evaluation of biological and antimicrobial properties of freeze-dried whey fermented by different strains of Lactobacillus plantarum
From the themed collection: Food & Function Recent HOT articles
Paper

Administration of Lactobacillus paracasei ameliorates type 2 diabetes in mice

Lactobacillus paracasei TD062 with high inhibitory activity ameliorated lipid metabolism, oxidative stress, glucose metabolism and the PI3K/Akt pathway in diabetic mice, and the effects were dose-dependent to some extent.

Graphical abstract: Administration of Lactobacillus paracasei ameliorates type 2 diabetes in mice
From the themed collection: Food & Function Recent HOT articles
Paper

Thymus lanceolatus ethanolic extract protects human cells from t-BHP induced oxidative damage

This study aimed to investigate the ethanolic extract of T. lanceolatus, a species native to north-western Algeria, traditionally used as herbal tea, seasoning and a preservative for meat and poultry.

Graphical abstract: Thymus lanceolatus ethanolic extract protects human cells from t-BHP induced oxidative damage
From the themed collection: Food & Function Recent HOT articles
Open Access Paper

Impact of tart cherry juice on systolic blood pressure and low-density lipoprotein cholesterol in older adults: a randomized controlled trial

Hypertension and dyslipidemia are major risk factors for cardiovascular disease (CVD). Common treatments for high blood pressure (BP) and dyslipidemia include medications, but there is question as to whether natural sources may be adequate to reduce CVD risk factors.

Graphical abstract: Impact of tart cherry juice on systolic blood pressure and low-density lipoprotein cholesterol in older adults: a randomized controlled trial
From the themed collection: Food & Function Recent HOT articles
Paper

The protective effects of selenium-enriched Spirulina platensis on chronic alcohol-induced liver injury in mice

Se-SP prevents alcohol-induced liver damage due to its function in the recovery of antioxidase activities and inhibition of lipid peroxidation. Se-SP is protective against alcohol-induced liver injury by suppressing cell apoptosis, accompanied by autophagy and pyroptosis.

Graphical abstract: The protective effects of selenium-enriched Spirulina platensis on chronic alcohol-induced liver injury in mice
From the themed collection: Food & Function Recent HOT articles
Paper

Melissa officinalis L. ethanolic extract inhibits the growth of a lung cancer cell line by interfering with the cell cycle and inducing apoptosis

Melissa officinalis is a plant from the family Lamiaceae, native in Europe particularly in the Mediterranean region.

Graphical abstract: Melissa officinalis L. ethanolic extract inhibits the growth of a lung cancer cell line by interfering with the cell cycle and inducing apoptosis
From the themed collection: Food & Function Recent HOT articles
Open Access Paper

Hibiscus and lemon verbena polyphenols modulate appetite-related biomarkers in overweight subjects: a randomized controlled trial

Plant-derived polyphenols have shown potential to alleviate obesity-related pathologies by a multi-targeted mechanism in animal models and human intervention studies.

Graphical abstract: Hibiscus and lemon verbena polyphenols modulate appetite-related biomarkers in overweight subjects: a randomized controlled trial
From the themed collection: Food & Function Recent HOT articles
Paper

Food-grade monoglyceride oil foams: the effect of tempering on foamability, foam stability and rheological properties

The time-temperature history of monoglyceride-oleogels has a large influence on the foamability and foam stability of the corresponding oil foams.

Graphical abstract: Food-grade monoglyceride oil foams: the effect of tempering on foamability, foam stability and rheological properties
From the themed collection: Food & Function Recent HOT articles
Paper

Fermented goat milk consumption improves iron status and evokes inflammatory signalling during anemia recovery

In spite of the crucial role of the inflammatory state under anemic conditions, to date, no studies have directly tested the modulation of cytokines during iron overload.

Graphical abstract: Fermented goat milk consumption improves iron status and evokes inflammatory signalling during anemia recovery
From the themed collection: Food & Function Recent HOT articles
Paper

Incorporation of tocopherol-rich extracts from mushroom mycelia into yogurt

The tocopherol extract from Ganoderma lucidum proved to be the most suitable choice as a new functionalizing agent to be incorporated in yogurt.

Graphical abstract: Incorporation of tocopherol-rich extracts from mushroom mycelia into yogurt
From the themed collection: Food & Function Recent HOT articles
Paper

Carboxymethyl pachyman (CMP) reduces intestinal mucositis and regulates the intestinal microflora in 5-fluorouracil-treated CT26 tumour-bearing mice

The compound 5-fluorouracil (5-FU) is the first choice chemotherapeutic agent for the treatment of colorectal cancer (CRC), but intestinal mucositis is a primary limiting factor in anticancer therapy.

Graphical abstract: Carboxymethyl pachyman (CMP) reduces intestinal mucositis and regulates the intestinal microflora in 5-fluorouracil-treated CT26 tumour-bearing mice
From the themed collection: Food & Function Recent HOT articles
Paper

Anticancer potential against cervix cancer (HeLa) cell line of probiotic Lactobacillus casei and Lactobacillus paracasei strains isolated from human breast milk

The CFCS of Lactobacilli strains from human breast milk induced apoptosis in HeLa cells ROS related mitochondrial pathway.

Graphical abstract: Anticancer potential against cervix cancer (HeLa) cell line of probiotic Lactobacillus casei and Lactobacillus paracasei strains isolated from human breast milk
From the themed collection: Food & Function Recent HOT articles
Paper

Theoretical investigation of the swelling of polysaccharide microgels in sugar solutions

In this paper, we explain the increased swelling of crosslinked polysaccharide microgels by the increase of sugar concentration using a modified Flory–Rehner theory.

Graphical abstract: Theoretical investigation of the swelling of polysaccharide microgels in sugar solutions
From the themed collection: Food & Function Recent HOT articles
Paper

Camel milk attenuates methotrexate-induced kidney injury via activation of PI3K/Akt/eNOS signaling and intervention with oxidative aberrations

Methotrexate (MTX) is a classical chemotherapeutic agent with nephrotoxicity as the most disturbing adverse effect.

Graphical abstract: Camel milk attenuates methotrexate-induced kidney injury via activation of PI3K/Akt/eNOS signaling and intervention with oxidative aberrations
From the themed collection: Food & Function Recent HOT articles
Paper

Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor

Auraptene protects against hepatic fibrosis.

Graphical abstract: Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor
From the themed collection: Food & Function Recent HOT articles
Paper

Hepatoprotective activity of iridoids, seco-iridoids and analog glycosides from Gentianaceae on HepG2 cells via CYP3A4 induction and mitochondrial pathway

Gentianaceae herb extracts have been widely used as food additives, teas or medicinal remedies for various diseases and disorders of the human body.

Graphical abstract: Hepatoprotective activity of iridoids, seco-iridoids and analog glycosides from Gentianaceae on HepG2 cells via CYP3A4 induction and mitochondrial pathway
From the themed collection: Food & Function Recent HOT articles
Paper

Ultrasonicated Lespedeza cuneata extract prevents TNF-α-induced early atherosclerosis in vitro and in vivo

This study evaluated the use of ultrasonication to extract Lespedeza cuneata as a potential nutraceutical for preventing vascular inflammation.

Graphical abstract: Ultrasonicated Lespedeza cuneata extract prevents TNF-α-induced early atherosclerosis in vitro and in vivo
From the themed collection: Food & Function Recent HOT articles
Paper

Assessment of endocrine disruption potential of essential oils of culinary herbs and spices involving glucocorticoid, androgen and vitamin D receptors

Essential oils of culinary herbs and species influence transcriptional activities of nuclear receptor VDR and steroid hormones receptors AR and GR.

Graphical abstract: Assessment of endocrine disruption potential of essential oils of culinary herbs and spices involving glucocorticoid, androgen and vitamin D receptors
From the themed collection: Food & Function Recent HOT articles
Paper

Raspberry anthocyanin consumption prevents diet-induced obesity by alleviating oxidative stress and modulating hepatic lipid metabolism

Evidence indicates that raspberries have beneficial effects on chronic diseases.

Graphical abstract: Raspberry anthocyanin consumption prevents diet-induced obesity by alleviating oxidative stress and modulating hepatic lipid metabolism
From the themed collection: Food & Function Recent HOT articles
108 items - Showing page 1 of 2

About this collection

This themed collection features articles published in Food & Function marked as HOT by the handling editor or as recommended by referees. Congratulations to all the authors whose articles are featured.

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