Themed collection Food & Function Review Articles 2023

The present work highlights preclinical and clinical studies assessing the cardiometabolic benefits of maqui berry supplementation and provides a prospective outlook on development of novel maqui-based therapeutics for metabolic diseases.

Hyperglycemia has become a global health problem due to changes in diet and lifestyle.

Processed oilseeds, combined with plant proteins, show potential as a protein source. They may have health benefits, but more clinical data are needed for confirmation.

American ginseng (Panax quinquefolius) has gained recognition as a medicinal and functional food homologous product with several pharmaceutical, nutritional, and industrial applications.

The effects of dietary lipids on cognition, both positive and negative, are mediated through the gut–brain axis by modulating metabolic, immune, neural, and endocrine pathways.

Dietary natural products could ameliorate diabetes via inhibiting carbohydrate hydrolyzing enzymes, exerting antioxidant, anti-inflammatory and anti-glycation effects, activating the PI3K/AKT pathway, modulating the gut microbiota, and so on.

Chia seeds regulate glucose, fat metabolism and alleviate inflammation by up- or down-regulating key gene targets in MAPK, AMPK, TGF-β, PPAR-γ, NF-κB, and IRS mediated insulin signaling pathways. However, some mechanisms of action are still unknown and require speculation and research.

Our results support the inclusión ofa well-balancedvegetariandietarypatternin the preventionand managementofcardiovascular diaseses.

This is a review of several vitamins (A, B, C, D, E, and K) that have been closely linked to the development of autism, exploring their mechanisms of action and significance in the prevention, mitigation, and treatment of autism.

GFD is positively associated with thyroid autoimmunity in CD patients that are children (<14 years).

Cognitive impairment (CI) is a multifaceted neurological condition that can trigger negative emotions and a range of concurrent symptoms, imposing significant public health and economic burdens on society.

The review comprehensively examines the intricate regulation of iron uptake and metabolism in the human body, shedding light on the essential role of various transporters and hormones in maintaining human health.

The biological functions of fatty acids and the lipids in which they are esterified are determined by their chain length, double bond position and geometry and other structural motifs such as the presence of methyl branches.

Evaluation of current clinical evidence on the effect of (poly)phenol-rich Vaccinium berries for sports nutrition.

The review critically discusses current insights into the physicochemical properties of bioactive molecules in kidney beans and focus on current knowledge of NSP structure and function on intestinal health and metabolism.

The structure of instant powder foods is significantly influenced by their ingredients. Instant powder foods potentially can be formulated with functional or beneficial compounds to provide health benefits.

Possible mechanisms involved in the regulation of diabetic kidney disease by garlic supplements.

Phytochemicals can provide health benefits via targeting estrogen receptors.

We aimed to conduct a comprehensive review of the association between dietary fiber and the risk of mortality.

Ginger is a widespread source of herbal medicine and traditional spices.

Herein, we review the current state-of-the-art on the use of micro- and nano-delivery systems, a possible solution to some of the drawbacks associated with the incorporation of resveratrol in foods.

TPSO stands out not only for its abundance of n-3 PUFAs but also for the presence of various important minor components that offer diverse health benefits. TPSO holds great potential as a superior oil that deserves global recognition and promotion.

Lycopene is an important pigment with an alkene skeleton from Lycopersicon esculentum, which is also obtained from some red fruits and vegetables.

Type 2 diabetes mellitus (T2DM) is one of the most prevalent diseases in modern society, governed by both genetic and environmental factors, such as nutritional habits. Dietary habits have a relevant impact on its development.

Steps of the NLRP3 inflammasome activation pathway where some selected polyphenols have shown a positive modulatory effect on different cardiometabolic alterations.

Preclinical studies have shown the benefits of n-3 polyunsaturated fatty acid (n-3 PUFA) on dementia and cognitive impairment, yet the results of clinical randomized controlled trials (RCTs) performed to date are conflicting.

Research on the nutritional and medicinal properties of wild edible mushrooms has witnessed a significant surge in recent years.

The synthesis and metabolism of bile acids (BAs) have been implicated in various metabolic diseases, including obesity and diabetes.

Compared to brown and white rice, black rice is rich in bioactive components, including γ-oryzanols, γ-aminobutyric acid, phenolic compounds, and anthocyanins, which makes it highly valuable for development and use.

Iron deficiency is a significant cause of iron deficiency anemia (IDA).

The study of all chemical processes involving metabolites is known as metabolomics.

A summary of the mechanisms of various ginsenosides in the treatment of lung cancer and pulmonary inflammatory diseases.

Ginsenosides resist the aging by regulating multiple signaling pathways.

The choice of the time interval between ‘bacteria and drug’ should be based on the metabolism of antibiotics, different probiotics, probiotic antimicrobial resistance and dosage, the baseline gut ecological environment, and the host immune level.

The incidences of short-term or long-term adverse maternal and fetal outcomes caused by maternal diabetes are increasing.

LCDs were associated with 43% risk of CHD, which suggests that vigilance is necessary for long-term adherence to such dietary pattern.

This review presents recent findings on edible insect proteins and extraction techniques. Explores insect peptide bioactivity and bioinformatics to predict peptide features. Covers insect allergens and processing methods to mitigate allergenicity.

The interactions of starch with polyphenol under green methods.

Bromelain, an enzyme obtained from pineapple, has now been identified as having versatile pharmaceutical applications. The last decade has witnessed a paradigm shift for bromelain from food to a potential drug candidate.

Evening primrose oil has attracted considerable interest worldwide because of its bioactive constituents and numerous functions in foods and health.

Under the action of natural products, microorganisms participate in a complete cycle of the “gut-brain-skin” axis linkage mechanism, thereby regulating the development of atopic dermatitis.

Humans are unique indiscriminate carotenoid accumulators, so the role of carotenoids as dietary antioxidants with or without enzymatic conversion attracts renewed attention from the standpoint of health promotion and disease prevention.

The human milk oligosaccharides (HMOs) can play a role as prebiotics in the treatment and prevention of gut inflammation.

A plant-based dietary pattern is associated with reduced SUA levels and a lower risk of hyperuricemia. An animal-based dietary pattern is associated with elevated SUA levels and an increased risk of hyperuricemia.

There are three main pathways by which polyphenols reduce ROS: direct scavenging, regulation by brain-gut axis signaling and regulation by intestinal flora.

The fruit of Phyllanthus emblica Linn., which mainly grows in tropical and subtropical regions, is well-known for its medicine and food homology properties. The fruit is rich in polyphenols and has shown advantages in the field of oral health management.

Microbiota dysbiosis and metabolic syndrome, consequences of a non-adequate diet, generate a feedback pathogenic state implicated in Alzheimer's disease development.

Functional ingredients have multiple health benefits for humans, but are sensitive to oxidative degradation during manufacture and storage, and have poor chemical stability and reduced bioaccessibility.

The effects of cell structure modification on starch digestibility were reviewed, and current reports were summarized according to a new classification.

Heart failure (HF) is associated with a deficiency in blood levels of coenzyme Q10 (CoQ10), and its supplementation has been proposed.

Moderate red wine intake improves cardiovascular health by reducing oxidative stress, and playing an important role on lipid and glucose metabolism.

C3G can be enzymatically decomposed into aglycone and further degraded into phenolic substances. Next, C3G was degraded in the distal small intestine and large intestine, and then entered the liver through blood circulation.

Branched-chain fatty acids (BCFAs) have recently emerged as a group of functional fatty acids that are widely distributed in various foodstuffs, including dairy products, ruminant meat products, and fermented foods.

Maternal vitamin D deficiency affects brain development during foetal life and causes alterations that may persist into adulthood.

Dietary agents in mitigating radiation-induced behavioural and cognitive changes.

As the simultaneous presence of proteins and polysaccharides can significantly affect the properties of hydrogels, the current article can throw light on the differences between single-polymeric gels and the binary ones.

The creation of bioactive peptides (BPs) from dietary proteins holds considerable promise for the expansion of functional foods and nutraceuticals.

This systematic review and meta-analysis of the association between dietary patterns and excessive gestational weight gain (EGWG) were conducted to recommend healthy dietary patterns instead of unhealthy dietary patterns for pregnant women to prevent EGWG.

This paper reviewed the vasculoprotective effects of hawthorn extracts and their mechanisms. Clinical trials have shown that hawthorn extracts reduce the risk factors for cardiovascular disease and the risk of poor prognosis.

Plant-based milk alternatives have become increasingly desirable due to their sustainability and the increased consumer awareness of health.

Parkinson's disease (PD) is the second most common neurodegenerative disease (ND).

Athletes are increasingly consuming (poly)phenol supplements to modify oxidative stress and/or exercise-induced inflammation, in the hope that this will enhance exercise performance.

The low solubility, high crystallinity, and instability of phytosterols restrict their bioavailability in foods. Phytosterol structures, carriers, and food matrices have important effects on the delivery, absorption, and bioactivity of phytosterols.

The relationship between the consumption of foods with added fructose and non-alcoholic fatty liver disease (NAFLD) was inconsistent in previous epidemiological studies, and no meta-analysis has been performed on the pooled results.

Diet composition has a great impact on body composition.

The emergence of pathogens resistant to conventional antibiotics and the growing interest in developing alternative natural antimicrobial agents have prompted a search for plant-derived antimicrobial peptides (PAMPs) in recent years.

The anti-inflammatory, anti-oxidant, anti-apoptotic and blood-brain barrier protective activities of dietary quercetin can prevent cerebral ischemia, and its nano-formulation can improve quercetin bioavailability.

β-Sitosterol, a dietary component, prevents OVA-induced food allergy by ameliorating the intestinal barrier function and reshaping the intestinal microbiota.

The human population is becoming old and ageing, which is related to a variety of health issues, such as Alzheimer's disease, obesity, diabetes, hypercholesterolemia, and some types of cancers like colorectal cancer.

Natural polysaccharides can exert their hypoglycemic effects by improving glucose metabolism, suppressing inflammation-induced insulin resistance and alleviating mitochondrial dysfunction.