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Themed collection Analytical Methods Recent HOT articles

140 items - Showing page 1 of 2
Paper

Simple label-free fluorescence detection of apurinic/apyrimidinic endonuclease 1 activity and its inhibitor using the abasic site-binding fluorophore

A label-free fluorescence detection method for apurinic/apyrimidinic endonuclease 1 activity was reported based on the abasic site-binding fluorophore.

Graphical abstract: Simple label-free fluorescence detection of apurinic/apyrimidinic endonuclease 1 activity and its inhibitor using the abasic site-binding fluorophore
From the themed collection: Analytical Methods Recent HOT articles
Open Access Communication

Measuring elasticity of wet cellulose fibres with AFM using indentation and a linearized Hertz model

The mechanical properties of different pulp fibres in liquid were measured using an atomic force microscope.

Graphical abstract: Measuring elasticity of wet cellulose fibres with AFM using indentation and a linearized Hertz model
From the themed collection: Analytical Methods Recent HOT articles
Communication

A non-reductive electrochemical sensor for ultrasensitive detection of pM-level TNT

Most of the current electrochemical sensors for the detection of nitroaromatic explosives directly exploit the reduction of nitro groups at the electrode.

Graphical abstract: A non-reductive electrochemical sensor for ultrasensitive detection of pM-level TNT
From the themed collection: Analytical Methods Recent HOT articles
Paper

Heavy metal ion discrimination based on distinct interaction between single-stranded DNA and methylene blue

In this work, we developed a facile and extensible colorimetric sensor array based on different interactions between methylene blue (MB) and single-stranded DNA (ssDNA) for the discrimination of heavy metal ions.

Graphical abstract: Heavy metal ion discrimination based on distinct interaction between single-stranded DNA and methylene blue
From the themed collection: Analytical Methods Recent HOT articles
Communication

Selective turn-on detection of low levels of cysteine and homocysteine based on fluorescent hydroxyapatite nanoparticles

Fluorescence assay of low levels of biothiols, such as cysteine and homocysteine, based on hydroxyapatite nanoparticles is reported.

Graphical abstract: Selective turn-on detection of low levels of cysteine and homocysteine based on fluorescent hydroxyapatite nanoparticles
From the themed collection: Analytical Methods Recent HOT articles
Paper

Simple spectrofluorimetric methods for determination of two pharmaceutically active compounds; salmeterol and trimebutine in their raw materials and pharmaceutical dosage forms in nano concentrations and testing of content uniformity

Simple and rapid spectrofluorimetric methods based on the native fluorescence properties of salmeterol in its aqueous solution and enhanced native fluorescence of trimebutine were developed.

Graphical abstract: Simple spectrofluorimetric methods for determination of two pharmaceutically active compounds; salmeterol and trimebutine in their raw materials and pharmaceutical dosage forms in nano concentrations and testing of content uniformity
From the themed collection: Analytical Methods Recent HOT articles
Paper

The stability of 57 consensus values in a proficiency test material re-issued blind after an interval of 18 years

Despite changes in the analytical methodology and the population of participant laboratories, there was remarkably little change in the consensus values.

Graphical abstract: The stability of 57 consensus values in a proficiency test material re-issued blind after an interval of 18 years
From the themed collection: Analytical Methods Recent HOT articles
Paper

Rapid classification of plastics by laser-induced breakdown spectroscopy (LIBS) coupled with partial least squares discrimination analysis based on variable importance (VI-PLS-DA)

Combination of LIBS and VI-PLS-DA is a promising approach to achieve the online analysis and process control of waste plastic recycling.

Graphical abstract: Rapid classification of plastics by laser-induced breakdown spectroscopy (LIBS) coupled with partial least squares discrimination analysis based on variable importance (VI-PLS-DA)
From the themed collection: Analytical Methods Recent HOT articles
Open Access Paper

Chiral analysis of β-methylamino alanine (BMAA) enantiomers after (+)-1-(9-fluorenyl)-ethyl chloroformate (FLEC) derivatization and LC-MS/MS

A developed method for chiral analysis of neurotoxin β-methylamino alanine (BMAA) allowed detection of D-BMAA in cycad seed samples.

Graphical abstract: Chiral analysis of β-methylamino alanine (BMAA) enantiomers after (+)-1-(9-fluorenyl)-ethyl chloroformate (FLEC) derivatization and LC-MS/MS
From the themed collection: Analytical Methods Recent HOT articles
Paper

Fluorescent probe based on rosamine with pyridinium unit for hydrogen sulfide detection in mitochondria

A mitochondria-targeted fluorescence probe based on rosamine with pyridinium unit was prepared for detecting hydrogen sulfide.

Graphical abstract: Fluorescent probe based on rosamine with pyridinium unit for hydrogen sulfide detection in mitochondria
From the themed collection: Analytical Methods Recent HOT articles
Paper

Silicon quantum dot involved luminol chemiluminescence and its sensitive detection of dopamine

Water dispersible silicon quantum dots (SiQDs) were synthesized by in situ growth under microwave irradiation.

Graphical abstract: Silicon quantum dot involved luminol chemiluminescence and its sensitive detection of dopamine
From the themed collection: Analytical Methods Recent HOT articles
Paper

A direct electron transfer biosensor based on a horseradish peroxidase and gold nanotriangle modified electrode and electrocatalysis

Gold nanotriangles (AuNTs) were used as a modifier on the surface of a carbon ionic liquid electrode (CILE), which was applied to realize direct electrochemistry and electrocatalysis of horseradish peroxidase (HRP).

Graphical abstract: A direct electron transfer biosensor based on a horseradish peroxidase and gold nanotriangle modified electrode and electrocatalysis
From the themed collection: Analytical Methods Recent HOT articles
Paper

Disposable graphene sensor with an internal reference electrode for stripping analysis of heavy metals

An all-graphene-based disposable sensor with a ‘built in’ internal reference was applied for the stripping analysis of heavy metals.

Graphical abstract: Disposable graphene sensor with an internal reference electrode for stripping analysis of heavy metals
From the themed collection: Analytical Methods Recent HOT articles
Paper

An early fire sensor based on infrared gas analytical methods

A CO sensor based on a 2.33 μm DFB laser and the WMS technique for early fire detection.

Graphical abstract: An early fire sensor based on infrared gas analytical methods
From the themed collection: Analytical Methods Recent HOT articles
Paper

Controllable synthesis of cellulose benzoates for understanding of chiral recognition mechanism and fabrication of highly efficient chiral stationary phases

The core of enantioseparation is to combine the hydrophobic helical conformation of cellulose derivatives with weak non-enantioselective interactions.

Graphical abstract: Controllable synthesis of cellulose benzoates for understanding of chiral recognition mechanism and fabrication of highly efficient chiral stationary phases
From the themed collection: Analytical Methods Recent HOT articles
Paper

New paper-based microfluidic tools for the analysis of blood serum protein and creatinine built via aerosolized deposition of polycaprolactone

Aerosolized deposition of a polymer solution to a substrate allows for rapid, low-cost fabrication of 3D microfluidic devices for bioassays.

Graphical abstract: New paper-based microfluidic tools for the analysis of blood serum protein and creatinine built via aerosolized deposition of polycaprolactone
From the themed collection: Analytical Methods Recent HOT articles
Paper

A novel pyrene-switching aptasensor for the detection of bisphenol A

A novel competition-mediated pyrene-switching aptasensor was developed for sensitive and selective detection of BPA in buffer and real water samples.

Graphical abstract: A novel pyrene-switching aptasensor for the detection of bisphenol A
From the themed collection: Analytical Methods Recent HOT articles
Paper

Determination of Cu2+ and biothiols by novel red fluorescent hybrid nanoparticles

Red fluorescent hybrid nanoparticles (NPG@PFBD) have been designed and synthesized successfully.

Graphical abstract: Determination of Cu2+ and biothiols by novel red fluorescent hybrid nanoparticles
From the themed collection: Analytical Methods Recent HOT articles
Paper

Optimization of a microchip electrophoresis method with electrochemical detection for the determination of nitrite in macrophage cells as an indicator of nitric oxide production

A transient isotachophoresis separation and Pt black working electrode allow detection of nitrite in stimulated macrophage cells with improved sensitivity.

Graphical abstract: Optimization of a microchip electrophoresis method with electrochemical detection for the determination of nitrite in macrophage cells as an indicator of nitric oxide production
From the themed collection: Analytical Methods Recent HOT articles
Paper

A sensitive electrochemical sensor based on reduced graphene oxide/Fe3O4 nanorod composites for detection of nitrofurantoin and its metabolite

In this work, a reduced graphene oxide/Fe3O4 nanorod composite (rGO/Fe3O4NR) modified glassy carbon electrode was fabricated for nitrofurantoin (NFT) and 1-aminohydantoin (AHD) detection.

Graphical abstract: A sensitive electrochemical sensor based on reduced graphene oxide/Fe3O4 nanorod composites for detection of nitrofurantoin and its metabolite
From the themed collection: Analytical Methods Recent HOT articles
Paper

SERS-fluorescence bimodal nanoprobes for in vitro imaging of the fatty acid responsive receptor GPR120

Multi-functional hybrid nanoparticles are synthesized for fluorescence-SERS bimodal imaging of GPR120 in vitro.

Graphical abstract: SERS-fluorescence bimodal nanoprobes for in vitro imaging of the fatty acid responsive receptor GPR120
From the themed collection: Analytical Methods Recent HOT articles
Paper

A strategy to facilitate the assembly of DNA and upconversion nanoparticles for biosensor construction

We coated upconversion nanoparticles with polydopamine as an effective and convenient strategy to assemble them with DNA and therefore construct a biosensor with DNA-templated silver nanoparticles as the LRET donor–acceptor pair for a proof-of-concept target detection.

Graphical abstract: A strategy to facilitate the assembly of DNA and upconversion nanoparticles for biosensor construction
From the themed collection: Analytical Methods Recent HOT articles
Paper

Magnetic surface molecularly imprinted polymeric microspheres using gallic acid as a segment template for excellent recognition of ester catechins

The magnetic molecularly imprinted polymers (MMIPs) with gallic acid as a segment template can simultaneously recognize and separate ester catechins as a whole form tea samples.

Graphical abstract: Magnetic surface molecularly imprinted polymeric microspheres using gallic acid as a segment template for excellent recognition of ester catechins
From the themed collection: Analytical Methods Recent HOT articles
Paper

Amino-functionalized CdSe/ZnS quantum dot-based lateral flow immunoassay for sensitive detection of aflatoxin B1

In this study, highly fluorescent amino-functionalized CdSe/ZnS QDs coated with amphiphilic N-alkylated poly(ethyleneimine) have been synthesized and applied as fluorescent probes in LFIA strips for on-site determination of AFB1.

Graphical abstract: Amino-functionalized CdSe/ZnS quantum dot-based lateral flow immunoassay for sensitive detection of aflatoxin B1
From the themed collection: Analytical Methods Recent HOT articles
Paper

A “turn-on” fluorescence sensor for ascorbic acid based on graphene quantum dots via fluorescence resonance energy transfer

For the first time, a FRET nanosensor for AA was developed using GQDs as the energy donors and SQA-iron(III) as the energy acceptors.

Graphical abstract: A “turn-on” fluorescence sensor for ascorbic acid based on graphene quantum dots via fluorescence resonance energy transfer
From the themed collection: Analytical Methods Recent HOT articles
Paper

Quantification of cocaine and its adulterants by nuclear magnetic resonance spectroscopy without deuterated solvents (No-D qNMR)

A new analytical method was developed to quantify cocaine and some adulterants using nuclear magnetic resonance spectroscopy without the use of deuterated solvents.

Graphical abstract: Quantification of cocaine and its adulterants by nuclear magnetic resonance spectroscopy without deuterated solvents (No-D qNMR)
From the themed collection: Analytical Methods Recent HOT articles
Paper

Quantitative comparison of three representative staining methods for the development of multichannel colorimetric biochips

Quantitative comparison of three representative staining methods for developing multichannel colorimetric biochips, which allow visual detection of multiple cancer markers.

Graphical abstract: Quantitative comparison of three representative staining methods for the development of multichannel colorimetric biochips
From the themed collection: Analytical Methods Recent HOT articles
Paper

A smart and sensitive sensing platform to monitor the extracellular concentration of hydrogen peroxide in rat brain microdialysates during pathological processes based on mesoporous silica nanoparticles

An effective and biocompatible H2O2 stimuli-responsive chemical sensing platform has been developed based on mesoporous silica nanoparticles (MSNPs).

Graphical abstract: A smart and sensitive sensing platform to monitor the extracellular concentration of hydrogen peroxide in rat brain microdialysates during pathological processes based on mesoporous silica nanoparticles
From the themed collection: Analytical Methods Recent HOT articles
Paper

Aggregated-fluorescent detection of PFAS with a simple chip

In this study, aggregation-induced emission luminogens (AIEgen) are used for the detection of per- and poly-fluoroalkyl substances (PFAS) including perfluorooctanoic acid (PFOA), perfluorooctanesulfonic acid (PFOS) and 1H,1H,2H,2H-perfluorooctanesulfonic acid (6:2FTS).

Graphical abstract: Aggregated-fluorescent detection of PFAS with a simple chip
From the themed collection: Analytical Methods Recent HOT articles
Paper

A nuclease protection ELISA assay for colorimetric and electrochemical detection of nucleic acids

The NP-ELISA combines traditional nuclease protection with optical and electrochemical enzymatic readout for nucleic acid detection.

Graphical abstract: A nuclease protection ELISA assay for colorimetric and electrochemical detection of nucleic acids
From the themed collection: Analytical Methods Recent HOT articles
Paper

A colorimetric method for cysteine determination based on the peroxidase-like activity of ficin

H2O2 could oxidize TMB to blue-colored oxTMB with catalysis by ficin. L-Cys competed with TMB for H2O2 leading to fading of the chromogenic reaction.

Graphical abstract: A colorimetric method for cysteine determination based on the peroxidase-like activity of ficin
From the themed collection: Analytical Methods Recent HOT articles
Open Access Paper

Fluorescence signal-to-noise optimisation for real-time PCR using universal reporter oligonucleotides

In this study we optimised the fluorescence signal generation of contact quenched universal reporter oligonucleotides.

Graphical abstract: Fluorescence signal-to-noise optimisation for real-time PCR using universal reporter oligonucleotides
From the themed collection: Analytical Methods Recent HOT articles
Open Access Paper

A novel EI-GC/MS method for the accurate quantification of anti-aging compound oleoylethanolamine in C. elegans

A novel GC-MS method for the quantification of oleoylethanolamine in C. elegans.

Graphical abstract: A novel EI-GC/MS method for the accurate quantification of anti-aging compound oleoylethanolamine in C. elegans
From the themed collection: Analytical Methods Recent HOT articles
Paper

A fast and novel internal calibration method for quantitative Raman measurements on aqueous solutions

Quantitative Raman spectroscopy despite the experimental parameter variations and overlapping solute and solvent Raman bands.

Graphical abstract: A fast and novel internal calibration method for quantitative Raman measurements on aqueous solutions
From the themed collection: Analytical Methods Recent HOT articles
Paper

Encapsulating a ruthenium(II) complex into metal organic frameworks to engender high sensitivity for dopamine electrochemiluminescence detection

In this contribution, an ultra-sensitive electrochemiluminescence (ECL) sensor was proposed for dopamine (DA) detection based on ruthenium(II) complex (tris(2,2-bipyridyl)dichlororuthenium(II) hexahydrate, Ru(bpy)32+) functionalized Zn(II) metal–organic frameworks (Ru-MOFs).

Graphical abstract: Encapsulating a ruthenium(ii) complex into metal organic frameworks to engender high sensitivity for dopamine electrochemiluminescence detection
From the themed collection: Analytical Methods Recent HOT articles
Paper

Enhanced microchip electrophoresis separations combined with electrochemical detection utilizing a capillary embedded in polystyrene

A polystyrene–PDMS device utilizing an embedded fused silica capillary and electrochemical detection was used for improved efficiency separations of catecholamines.

Graphical abstract: Enhanced microchip electrophoresis separations combined with electrochemical detection utilizing a capillary embedded in polystyrene
From the themed collection: Analytical Methods Recent HOT articles
Paper

Novel, sensitive and selective colorimetric detection of arsenate in aqueous solution by a Fenton-like reaction of Fe3O4 nanoparticles

In this paper, we present a novel colorimetric sensor for the detection of arsenate in aqueous solution.

Graphical abstract: Novel, sensitive and selective colorimetric detection of arsenate in aqueous solution by a Fenton-like reaction of Fe3O4 nanoparticles
From the themed collection: Analytical Methods Recent HOT articles
Paper

Two-photon fluorescent probe for hypoxic cancer stem cells by responding to endogenous nitroreductase

A two-photon fluorescent probe to detect the NTR in 3D cultured-cancer stem cells and monitor the hypoxic microenvironment in vitro. This novel probe was hoped to apply for disease-relevant hypoxia detection in the biomedical research fields.

Graphical abstract: Two-photon fluorescent probe for hypoxic cancer stem cells by responding to endogenous nitroreductase
From the themed collection: Analytical Methods Recent HOT articles
Paper

Determination of polycyclic aromatic hydrocarbons with molecular mass 302 in standard reference material 1597a by reversed-phase liquid chromatography and stop-flow fluorescence detection

NPLC-RPLC/FL and stop-flow fluorescence spectral analysis for the six-ring MM 302 PAH isomers in SRM 1597a.

Graphical abstract: Determination of polycyclic aromatic hydrocarbons with molecular mass 302 in standard reference material 1597a by reversed-phase liquid chromatography and stop-flow fluorescence detection
From the themed collection: Analytical Methods Recent HOT articles
Paper

A Pt and Pd bimetal nanowire based stereoselective sensor for the discrimination of ascorbic acid and isoascorbic acid

A simple Pt and Pd bimetal nanowire based stereoselective sensor for the recognition of ascorbic acid and isoascorbic acid.

Graphical abstract: A Pt and Pd bimetal nanowire based stereoselective sensor for the discrimination of ascorbic acid and isoascorbic acid
From the themed collection: Analytical Methods Recent HOT articles
Communication

Glycerophospholipids and sphingolipids correlate with poor prognostic genotypes of human papillomavirus in cervical cancer: global lipidomics analysis

Human papillomavirus (HPV), an important causative factor for cervical cancer, alters lipid metabolism.

Graphical abstract: Glycerophospholipids and sphingolipids correlate with poor prognostic genotypes of human papillomavirus in cervical cancer: global lipidomics analysis
From the themed collection: Analytical Methods Recent HOT articles
Communication

One-step detection of hexokinase activity using a personal glucose meter

Using commercially available personal glucose meters for the determination of hexokinase activity.

Graphical abstract: One-step detection of hexokinase activity using a personal glucose meter
From the themed collection: Analytical Methods Recent HOT articles
Paper

Ultrasensitive and direct fluorescence detection of RDX explosive vapor via side-chain terminal functionalization of a polyfluorene probe

We have designed and synthesized a polyfluorene probe with side-chain terminals functionalized with Boc-NH– units (PF6-Boc) for ultrasensitive RDX explosive vapor detection.

Graphical abstract: Ultrasensitive and direct fluorescence detection of RDX explosive vapor via side-chain terminal functionalization of a polyfluorene probe
From the themed collection: Analytical Methods Recent HOT articles
Paper

Advancement of analytical modes in a multichannel, microfluidic droplet-based sample chopper employing phase-locked detection

Multichannel droplet-based microfluidic sample chopper (μChopper) allows continuous calibration, nanoliter sampling, and protein quantification in human serum.

Graphical abstract: Advancement of analytical modes in a multichannel, microfluidic droplet-based sample chopper employing phase-locked detection
From the themed collection: Analytical Methods Recent HOT articles
Paper

Chronocoulometric method for the evaluation of antioxidant capacity of medicinal plant tinctures

Antioxidant capacity of medicinal plant tinctures based on chronocoulometric data on poly(gallic acid)/MWNT-modified electrode.

Graphical abstract: Chronocoulometric method for the evaluation of antioxidant capacity of medicinal plant tinctures
From the themed collection: Analytical Methods Recent HOT articles
Paper

Copper nanoclusters with strong fluorescence emission as a sensing platform for sensitive and selective detection of picric acid

The detection of picric acid has been developed based on a combined effect of molecular interactions and inner filter effect.

Graphical abstract: Copper nanoclusters with strong fluorescence emission as a sensing platform for sensitive and selective detection of picric acid
From the themed collection: Analytical Methods Recent HOT articles
Paper

An ultrasensitive electrochemiluminescent D-alanine biosensor based on the synergetic catalysis of a hemin-functionalized composite and gold–platinum nanowires

Herein, an ultrasensitive and stereo-selective electrochemiluminescent (ECL) biosensor based on ECL signal amplification of luminol by the synergetic catalysis of a hemin-functionalized composite and gold–platinum nanowires (Au-PtNWs) has been designed for the detection of D-alanine (D-Ala).

Graphical abstract: An ultrasensitive electrochemiluminescent d-alanine biosensor based on the synergetic catalysis of a hemin-functionalized composite and gold–platinum nanowires
From the themed collection: Analytical Methods Recent HOT articles
Paper

Paper based lateral flow immunoassay for the enumeration of Escherichia coli in urine

In this experimental study, we developed lateral flow immunoassay strips for the detection of Escherichia coli.

Graphical abstract: Paper based lateral flow immunoassay for the enumeration of Escherichia coli in urine
From the themed collection: Analytical Methods Recent HOT articles
Paper

Rapid fabrication of versatile omni-directional and long-distance three-dimensional flow paper-fluidic analytical devices using a cut-and-insert method for biomedical applications

Paper fluidics has recently offered an approach to precisely guide liquid flow in analytical devices with a low-cost regime.

Graphical abstract: Rapid fabrication of versatile omni-directional and long-distance three-dimensional flow paper-fluidic analytical devices using a cut-and-insert method for biomedical applications
From the themed collection: Analytical Methods Recent HOT articles
Paper

Point-of-care monitoring of intracellular glutathione and serum triglyceride levels using a versatile personal glucose meter

Portable, cost-effective and quantitative detection of various targets related to health at home and in the field has the potential to revolutionize medical diagnostics.

Graphical abstract: Point-of-care monitoring of intracellular glutathione and serum triglyceride levels using a versatile personal glucose meter
From the themed collection: Analytical Methods Recent HOT articles
Paper

Determination of sample stability for whole blood parameters using formal experimental design

Hematocrit increases with storage time, leading to a decrease in transport distance in our paper-based hematocrit device.

Graphical abstract: Determination of sample stability for whole blood parameters using formal experimental design
From the themed collection: Analytical Methods Recent HOT articles
Paper

A NIR ratiometric fluorescent probe for the ‘naked-eye’ detection of endogenous hypochlorous acid in practical samples

We designed a near-infrared ratiometric (2.1 to 15.3, I608/I735) fluorescent probe with a quick response (20 s) based on cyanine polyene derivatives. This probe can detect endogenous hypochlorous acid in HepG-2 cells and determine the hypochlorous acid content in 84 disinfectant and other actual samples.

Graphical abstract: A NIR ratiometric fluorescent probe for the ‘naked-eye’ detection of endogenous hypochlorous acid in practical samples
From the themed collection: Analytical Methods Recent HOT articles
Paper

ATR-FTIR spectroscopy with equidistant combination PLS method applied for rapid determination of glycated hemoglobin

A rapid quantification method of glycated hemoglobin (HbA1c) is proposed based on ATR-FTIR spectroscopy in human hemolysate samples.

Graphical abstract: ATR-FTIR spectroscopy with equidistant combination PLS method applied for rapid determination of glycated hemoglobin
From the themed collection: Analytical Methods Recent HOT articles
Paper

Sensitive determination of psoralen and isopsoralen in Fructus Psoraleae by online solid phase microextraction with a porphyrin-based porous organic polymer modified capillary

A novel porphyrin based porous organic polymer modified capillary (PPOP-capillary) was prepared for the extraction of psoralen and isopsoralen in Fructus Psoraleae.

Graphical abstract: Sensitive determination of psoralen and isopsoralen in Fructus Psoraleae by online solid phase microextraction with a porphyrin-based porous organic polymer modified capillary
From the themed collection: Analytical Methods Recent HOT articles
Paper

Contrasting confocal XRF with micro-SORS: a deep view within micrometric painted stratigraphy

The study presents the application of combined micro-Spatially Offset Raman Spectroscopy (micro-SORS) and confocal X-ray fluorescence (confocal XRF) to the non-destructive investigation of micrometer scale stratified painted systems.

Graphical abstract: Contrasting confocal XRF with micro-SORS: a deep view within micrometric painted stratigraphy
From the themed collection: Analytical Methods Recent HOT articles
Paper

Ion mobility mass spectrometry workflows for characterizing bioactive isomer conformation, isomerization and drug–protein–liposome interaction

Ion mobility mass spectrometry enhances our ability to study conformational changes of bioactive isomers and their interactions with macromolecules.

Graphical abstract: Ion mobility mass spectrometry workflows for characterizing bioactive isomer conformation, isomerization and drug–protein–liposome interaction
From the themed collection: Analytical Methods Recent HOT articles
Paper

Triglyceride and high density lipoprotein cholesterol concentrations quantitative analysis in whole blood by FTIR-ATR spectroscopy and FT-Raman spectroscopy

The triglyceride (TG) to high density lipoprotein cholesterol ratio (TG/HDL-C) and the TG level itself have both been identified as a biomarker of insulin resistance, cardiovascular disease and a predictor for atherosclerosis.

Graphical abstract: Triglyceride and high density lipoprotein cholesterol concentrations quantitative analysis in whole blood by FTIR-ATR spectroscopy and FT-Raman spectroscopy
From the themed collection: Analytical Methods Recent HOT articles
Paper

Rapid extraction of trace bisphenol A in real water samples using hollow mesoporous silica surface dummy molecularly imprinted polymers

The HM-DMIPs displayed good affinity and excellent binding selectivity to BPA.

Graphical abstract: Rapid extraction of trace bisphenol A in real water samples using hollow mesoporous silica surface dummy molecularly imprinted polymers
From the themed collection: Analytical Methods Recent HOT articles
Paper

A sensitive and quantitative immunochromatographic assay for HBsAg based on novel red silica nanoparticles

An immunochromatographic assay (ICA) based on red silica nanoparticles (red-SiNPs) was developed for quantitative detection of hepatitis B surface antigen (HBsAg) in serum.

Graphical abstract: A sensitive and quantitative immunochromatographic assay for HBsAg based on novel red silica nanoparticles
From the themed collection: Analytical Methods Recent HOT articles
Paper

Electrochemical sensing for 1-chloro-4-nitrobenzene based on β-cyclodextrin/carbon nanohorn nanohybrids

β-cyclodextrin/carbon nanohorn nanohybrids were prepared for the electrochemical sensing of 1-chloro-4-nitrobenzene.

Graphical abstract: Electrochemical sensing for 1-chloro-4-nitrobenzene based on β-cyclodextrin/carbon nanohorn nanohybrids
From the themed collection: Analytical Methods Recent HOT articles
Paper

A novel chemiluminescence signal amplification strategy based on a capillary electrophoresis platform for highly sensitive competitive immunoassay of biomolecules

A novel chemiluminescence (CL) signal amplification strategy based on luminophore and antigen co-loaded gold nanoparticles was developed to improve the sensitivity of capillary electrophoresis CL assay.

Graphical abstract: A novel chemiluminescence signal amplification strategy based on a capillary electrophoresis platform for highly sensitive competitive immunoassay of biomolecules
From the themed collection: Analytical Methods Recent HOT articles
Paper

Surface-enhanced Raman scattering on a silver-coated TiO2 nanopore core needle biopsy for three dimensional chemical profiling

In vivo analyzing chemical significance under human skin has impinged a formidable challenge upon regular optical methods due to its intrinsic opaque property.

Graphical abstract: Surface-enhanced Raman scattering on a silver-coated TiO2 nanopore core needle biopsy for three dimensional chemical profiling
From the themed collection: Analytical Methods Recent HOT articles
Paper

Exploring MBTH as a spectrophotometric probe for the determination of total phenolic compounds in beverage samples

An alternative method using MBTH as a spectrophotometric probe for the determination of total phenolic compounds in samples of wines (red and white), coffees (instant and brewed), teas and infusions.

Graphical abstract: Exploring MBTH as a spectrophotometric probe for the determination of total phenolic compounds in beverage samples
From the themed collection: Analytical Methods Recent HOT articles
Paper

Improved method for spectrophotometric determination of ruthenium using 1,10-phenanthroline: application for analysis of complex compounds

A day-to-day fast, cheap and accurate analysis of ruthenium in complex compounds without forgoing distillation of ruthenium tetroxide was conducted.

Graphical abstract: Improved method for spectrophotometric determination of ruthenium using 1,10-phenanthroline: application for analysis of complex compounds
From the themed collection: Analytical Methods Recent HOT articles
Paper

Aluminum-doped NiO nanofibers as chemical sensors for selective and sensitive methanol detection

One-dimensional nanomaterials with controlled morphology have received considerable attention as chemical sensors.

Graphical abstract: Aluminum-doped NiO nanofibers as chemical sensors for selective and sensitive methanol detection
From the themed collection: Analytical Methods Recent HOT articles
Communication

Label-free colorimetric aptasensor for highly sensitive and selective detection of proteins by using PNA/DNA hybrids and a cyanine dye

A label-free colorimetric aptasensor that uses PNA/DNA hybrids and a cyanine dye (DiSC2(5)) was developed for highly sensitive and selective detection of proteins in aqueous solution.

Graphical abstract: Label-free colorimetric aptasensor for highly sensitive and selective detection of proteins by using PNA/DNA hybrids and a cyanine dye
From the themed collection: Analytical Methods Recent HOT articles
Communication

Monitoring the trans-membrane transport of single fluorescent silicon nanoparticles based on the force tracing technique

Based on the force tracing technique, the dynamic trans-membrane transport process of single SiNPs in living cells was monitored.

Graphical abstract: Monitoring the trans-membrane transport of single fluorescent silicon nanoparticles based on the force tracing technique
From the themed collection: Analytical Methods Recent HOT articles
Paper

Validation of a lateral flow immunoassay for the rapid determination of aflatoxins in maize by solvent free extraction

The analytical performances of a lateral flow immunoassay (AFLA-V AQUA™, Vicam a Waters Business) for the determination of aflatoxins in maize were evaluated according to Commission Regulation (EU) No. 519/2014.

Graphical abstract: Validation of a lateral flow immunoassay for the rapid determination of aflatoxins in maize by solvent free extraction
From the themed collection: Analytical Methods Recent HOT articles
Paper

4′-Aminobenzo-18-crown-6 functionalized magnetic nanoparticles as a solid-phase extraction adsorbent for the determination of Pb2+

A novel magnetic adsorbent for Pb2+ was synthesized based on 4′-aminobenzo-18-crown-6 (AB18C6) and Fe3O4–CHO via the Mannich reaction. It showed excellent adsorption and selectivity for Pb2+, and the established MSPE method had excellent potential, displaying the selective determination of trace Pb2+ from apples, milk and rice.

Graphical abstract: 4′-Aminobenzo-18-crown-6 functionalized magnetic nanoparticles as a solid-phase extraction adsorbent for the determination of Pb2+
From the themed collection: Analytical Methods Recent HOT articles
Paper

Direct and ultrasensitive fluorescence detection of PETN vapor based on a fuorene-dimer probe via a synergic backbone and side-chain tuning

Due to TPA attraction, the distance between PETN and 6TPA-2FT is shortened, and both PET and intermolecular forces are promoted.

Graphical abstract: Direct and ultrasensitive fluorescence detection of PETN vapor based on a fuorene-dimer probe via a synergic backbone and side-chain tuning
From the themed collection: Analytical Methods Recent HOT articles
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This collection represents the top 10% of research published in Analytical Methods. Featured articles are marked as HOT by the handling editor or as recommended by referees. Congratulations to all the authors whose articles are featured.

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