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Themed collection 2018 Journal of Materials Chemistry B HOT Papers

24 items
Review Article

Approaches to improve the biocompatibility and systemic circulation of inorganic porous nanoparticles

The exploitation of various inorganic nanoparticles as drug carriers and therapeutics is becoming increasingly common.

Graphical abstract: Approaches to improve the biocompatibility and systemic circulation of inorganic porous nanoparticles
Review Article

Tuning the optical properties of graphene quantum dots for biosensing and bioimaging

This review highlights new insights into the various strategies used to tune the optical features of graphene quantum dots, and their use as attractive and powerful probes for bio-sensing/imaging.

Graphical abstract: Tuning the optical properties of graphene quantum dots for biosensing and bioimaging
Review Article

Recent advances in nitric oxide delivery for antimicrobial applications using polymer-based systems

The present review highlights the recent developments in NO-releasing polymeric biomaterials for antimicrobial applications.

Graphical abstract: Recent advances in nitric oxide delivery for antimicrobial applications using polymer-based systems
Review Article

Combined therapies with nanostructured carbon materials: there is room still available at the bottom

Combining therapies on a sheet of carbon is possible!

Graphical abstract: Combined therapies with nanostructured carbon materials: there is room still available at the bottom
Communication

A long-lifetime iridium(III) complex for lysosome tracking with high specificity and a large Stokes shift

Investigating the role of lysosome dysfunction in cancer requires the development of efficient probes for lysosomes.

Graphical abstract: A long-lifetime iridium(iii) complex for lysosome tracking with high specificity and a large Stokes shift
Accepted Manuscript - Paper

Hierarchical nanocomposites of graphene oxide and PEGylated protoporphyrin as carriers to load doxorubicin hydrochloride for trimodal synergistic therapy

Accepted Manuscript - Paper

Growth Factor-Free Salt-leached Silk Scaffolds to Differentiate Endothelial Cells

Paper

Surface zwitterionization on versatile hydrophobic interfaces via a combined copolymerization/self-assembling process

A special surface modification for coating amphiphilic zwitterionic polymers in a single step for antifouling applications in complex media.

Graphical abstract: Surface zwitterionization on versatile hydrophobic interfaces via a combined copolymerization/self-assembling process
Paper

Unraveling the molecular mechanisms of thermo-responsive properties of silk-elastin-like proteins by integrating multiscale modeling and experiment

Adaptive hydrogels tailor-made from silk-elastin-like proteins (SELPs) possess excellent biocompatibility and biodegradability with properties that are tunable and responsive to multiple simultaneous external stimuli.

Graphical abstract: Unraveling the molecular mechanisms of thermo-responsive properties of silk-elastin-like proteins by integrating multiscale modeling and experiment
Paper

PLGA-based nanofibers with a biomimetic polynoradrenaline sheath for rapid in vivo sampling of tetrodotoxin and sulfonamides in pufferfish

PLGA nanofibers with PNA sheath modification achieve enhanced extraction performance and antibiofouling capacity for in vivo sampling in pufferfish.

Graphical abstract: PLGA-based nanofibers with a biomimetic polynoradrenaline sheath for rapid in vivo sampling of tetrodotoxin and sulfonamides in pufferfish
Paper

Highly sensitive fluorescence quantification of intracellular telomerase activity by repeat G-rich DNA enhanced silver nanoclusters

As an important biomarker for early cancer diagnosis and a valuable therapeutic target, the detection and monitoring of telomerase activity has attracted extensive attention.

Graphical abstract: Highly sensitive fluorescence quantification of intracellular telomerase activity by repeat G-rich DNA enhanced silver nanoclusters
Paper

Long-term delivery of rhIGF-1 from biodegradable poly(lactic acid)/hydroxyapatite@Eudragit double-layer microspheres for prevention of bone loss and articular degeneration in C57BL/6 mice

Insulin-like growth factor (IGF-1) has encouraged researchers to investigate its various potential therapeutic uses such as in the treatment of osteoporosis and repair of articular cartilage.

Graphical abstract: Long-term delivery of rhIGF-1 from biodegradable poly(lactic acid)/hydroxyapatite@Eudragit double-layer microspheres for prevention of bone loss and articular degeneration in C57BL/6 mice
Paper

Nano-sized paramagnetic and fluorescent fluorinated carbon fiber with high NIR absorbance for cancer chemo-photothermal therapy

We report a novel strategy to synthesize nano-sized, water-soluble and functionalized fluorinated carbon fiber oxide with high fluorescence, paramagnetism and NIR absorption for cancer chemo-photothermal therapy.

Graphical abstract: Nano-sized paramagnetic and fluorescent fluorinated carbon fiber with high NIR absorbance for cancer chemo-photothermal therapy
Paper

Exosomes separated based on the “STOP” criteria for tumor-targeted drug delivery

A new exosome-related drug delivery vehicle was explored based on the “STOP” criteria, dramatically promoting the clinical translation of exosomes.

Graphical abstract: Exosomes separated based on the “STOP” criteria for tumor-targeted drug delivery
Paper

Triple therapy of hepatocellular carcinoma with microRNA-122 and doxorubicin co-loaded functionalized gold nanocages

A combination of different therapy strategies has great potential to efficaciously treat malignant tumors, by virtue of their synergetic effects.

Graphical abstract: Triple therapy of hepatocellular carcinoma with microRNA-122 and doxorubicin co-loaded functionalized gold nanocages
Paper

The in vivo fates of plant viral nanoparticles camouflaged using self-proteins: overcoming immune recognition

Nanoparticle camouflage with serum albumin is formulation specific, does not produce antibodies against the coating, and shields nanoparticle antibody recognition.

Graphical abstract: The in vivo fates of plant viral nanoparticles camouflaged using self-proteins: overcoming immune recognition
Paper

Marriage of artificial catalase and black phosphorus nanosheets for reinforced photodynamic antitumor therapy

Pt nanoparticle-based artificial catalase is decorated on black phosphorus nanosheets, achieving reinforced photodynamic antitumor performance.

Graphical abstract: Marriage of artificial catalase and black phosphorus nanosheets for reinforced photodynamic antitumor therapy
Paper

Thermoresponsive double network cryogels from dendronized copolymers showing tunable encapsulation and release of proteins

Thermoresponsive double network cryogels were prepared from OEG-based dendronized copolymers with PVA, which can reversibly capture and release proteins.

Graphical abstract: Thermoresponsive double network cryogels from dendronized copolymers showing tunable encapsulation and release of proteins
Paper

Time-lapse live cell imaging to monitor doxorubicin release from DNA origami nanostructures

DNA origami nanostructures can serve as a promising carrier for drug delivery due to the outstanding programmability and biocompatibility.

Graphical abstract: Time-lapse live cell imaging to monitor doxorubicin release from DNA origami nanostructures
Paper

Size-controllable dual drug-loaded silk fibroin nanospheres through a facile formation process

Paclitaxel/doxorubicin-loaded silk fibroin nanospheres were prepared through a facile and green method and showed a synergistic effect on the anti-proliferative activity.

Graphical abstract: Size-controllable dual drug-loaded silk fibroin nanospheres through a facile formation process
Paper

Fabrication of gelatin-micropatterned surface and its effect on osteogenic differentiation of hMSCs

Micropatterned surface with different surface chemistries was fabricated for the direct comparison of their effect on the behaviors of hMSCs and to avoid any batch to batch variations during cell culture.

Graphical abstract: Fabrication of gelatin-micropatterned surface and its effect on osteogenic differentiation of hMSCs
Paper

Transglutaminase mediated PEGylation of nanobodies for targeted nano-drug delivery

The PEGylation of anti-EGFR nanobodies was achieved via a transglutaminase catalyzed reaction through a Q-tag. The nanobody tethered drug delivery system exhibits superior specificity to EGFR positive tumor cells.

Graphical abstract: Transglutaminase mediated PEGylation of nanobodies for targeted nano-drug delivery
Paper

Integration of antifouling and antibacterial properties in salt-responsive hydrogels with surface regeneration capacity

A new design for a new multifunctional hydrogel that integrates antimicrobial, antifouling, and surface regeneration properties for antimicrobial applications.

Graphical abstract: Integration of antifouling and antibacterial properties in salt-responsive hydrogels with surface regeneration capacity
Paper

A highly sensitive and rapidly responding fluorescent probe based on a rhodol fluorophore for imaging endogenous hypochlorite in living mice

A novel fluorescent probe RO610 was applied for the in vivo detection of endogenous ClO using living mice.

Graphical abstract: A highly sensitive and rapidly responding fluorescent probe based on a rhodol fluorophore for imaging endogenous hypochlorite in living mice
24 items

About this collection

This on-going web collection features all the articles published in Journal of Materials Chemistry B in 2018 marked as HOT, as recommended by referees.  Congratulations to all the authors whose articles are featured!

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