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Themed collection 2016 Journal of Materials Chemistry B Hot Papers

73 items - Showing page 1 of 2
Highlight

Microneedle-based sensors for medical diagnosis

The field of microneedle sensors is reviewed discussing current trends and future applications.

Graphical abstract: Microneedle-based sensors for medical diagnosis
Review Article

Processing and surface modification of polymer nanofibers for biological scaffolds: a review

This review discusses existing and emerging polymeric nanofiber fabrication techniques, fiber surface modification via post-processing, and their combined effects on cell adhesion, proliferation, and migration.

Graphical abstract: Processing and surface modification of polymer nanofibers for biological scaffolds: a review
Review Article

Heterotypic supramolecular hydrogels

We reviewed heterotypic supramolecular hydrogels containing more than one component to illustrate their promise as soft biomaterials.

Graphical abstract: Heterotypic supramolecular hydrogels
Open Access Review Article

Pluripotent stem cell derived hepatocytes: using materials to define cellular differentiation and tissue engineering

Pluripotent stem cell derived liver cells (hepatocytes) represent a promising alternative to primary tissue for biological and clinical applications.

Graphical abstract: Pluripotent stem cell derived hepatocytes: using materials to define cellular differentiation and tissue engineering
Review Article

Oxygen delivering biomaterials for tissue engineering

Various technologies have been developed to increase oxygen delivery in vivo and enhance the effectiveness of tissue engineering strategies. The article provides an overview of the underlying mechanisms driving these technologies.

Graphical abstract: Oxygen delivering biomaterials for tissue engineering
Review Article

Bioinspired materials for regenerative medicine: going beyond the human archetypes

Living organisms are skilful innovators and fabricators of materials, driven by the forces of evolution. We describe the translation process between natural material innovations and human tissue engineering.

Graphical abstract: Bioinspired materials for regenerative medicine: going beyond the human archetypes
Review Article

Nanostructure-based surface-enhanced Raman scattering biosensors for nucleic acids and proteins

Nanostructure-based SERS platforms have been developed for nucleic acid and protein detection ranging from label-free, labeled and multiplex analyses.

Graphical abstract: Nanostructure-based surface-enhanced Raman scattering biosensors for nucleic acids and proteins
Communication

Programmed planar-to-helical shape transformations of composite hydrogels with bioinspired layered fibrous structures

Composite hydrogels with both in-plane and out-of-plane structural gradient are fabricated by multi-step photolithography and exhibit programmed deformations and shape transformations under stimulation.

Graphical abstract: Programmed planar-to-helical shape transformations of composite hydrogels with bioinspired layered fibrous structures
Communication

Viscosity-controlled printing of supramolecular-polymeric hydrogels via dual-enzyme catalysis

Hybrid hydrogels based on a guanidinium-containing oligopeptide are prepared via dual-enzyme-triggered reactions. An extended time window is available for in situ viscosity-controlled 3D printing.

Graphical abstract: Viscosity-controlled printing of supramolecular-polymeric hydrogels via dual-enzyme catalysis
Communication

Facile green synthesis of calcium carbonate/folate porous hollow spheres for the targeted pH-responsive release of anticancer drugs

Calcium carbonate/folate porous hollow spheres were prepared in a facile manner and used for the targeted delivery and pH-responsive sustained release of anticancer drugs.

Graphical abstract: Facile green synthesis of calcium carbonate/folate porous hollow spheres for the targeted pH-responsive release of anticancer drugs
Open Access Communication

A novel method for the synthesis of 1,2-benzisoxazoline-3-one and its application to hypochlorite recognition

The reaction of salicylhydroxamic acid with hypochlorite produces 1,2-benzisoxazoline-3-one, a heterocycle that contains a fluorophore.

Graphical abstract: A novel method for the synthesis of 1,2-benzisoxazoline-3-one and its application to hypochlorite recognition
Communication

Ultrasensitive ELISA+ enhanced by dendritic mesoporous silica nanoparticles

Ultrasensitive ELISA+ assay has been developed with a 2000 times enhancement of detection sensitivity compared to the commercial ELISA kit in serum.

Graphical abstract: Ultrasensitive ELISA+ enhanced by dendritic mesoporous silica nanoparticles
Communication

High performance Cu/Cu2O nanohybrid electrocatalyst for nonenzymatic glucose detection

Described herein are Cu/Cu2O nanohybrids prepared via potential oscillation, and their high performance for nonenzymatic glucose detection applications.

Graphical abstract: High performance Cu/Cu2O nanohybrid electrocatalyst for nonenzymatic glucose detection
Communication

Target-triggered autonomous assembly of DNA polymer chains and its application in colorimetric nucleic acid detection

One-dimensional DNA polymer chains were obtained based on the catalyzed hairpin assembly and sticky end self-assembly, which led to a signal amplified colorimetric nucleic acid assay.

Graphical abstract: Target-triggered autonomous assembly of DNA polymer chains and its application in colorimetric nucleic acid detection
Communication

Fluorinated smart micelles as enzyme-responsive probes for 19F-magnetic resonance

Labeling smart PEG–dendron hybrids with fluorine-containing groups transform their micelles into enzyme-responsive probes for 19F-magnetic resonance.

Graphical abstract: Fluorinated smart micelles as enzyme-responsive probes for 19F-magnetic resonance
Communication

Cobalt disulfide nanowires as an effective fluorescent sensing platform for DNA detection

Cobalt disulfide nanowires are synthesized in solution using a facile two-step hydrothermal method for the first time and applied as an effective sensing platform for nucleic acid detection.

Graphical abstract: Cobalt disulfide nanowires as an effective fluorescent sensing platform for DNA detection
Communication

The first visually observable three-mode antibiotic switch and its relative 3D printing assisted applications

To regulate antibiotic treatments, the first visible three-mode antibiotic switch with residual removable characteristics was realized in this report.

Graphical abstract: The first visually observable three-mode antibiotic switch and its relative 3D printing assisted applications
Communication

N-dots as a photoluminescent probe for the rapid and selective detection of Hg2+ and Ag+ in aqueous solution

New N-dots for the sensitive and selective detection of Hg2+ and Ag+ without surface modifications.

Graphical abstract: N-dots as a photoluminescent probe for the rapid and selective detection of Hg2+ and Ag+ in aqueous solution
Paper

Versatile rare-earth oxide nanocomposites: enhanced chemo/photothermal/photodynamic anticancer therapy and multimodal imaging

A novel theranostic nanocomposite was assembled by a stepwise modification of rare-earth oxide nanoparticles; both the photothermal and photodynamic therapy effects are enhanced due to the effective light protection of a two-photon sensitized Eu3+ complex.

Graphical abstract: Versatile rare-earth oxide nanocomposites: enhanced chemo/photothermal/photodynamic anticancer therapy and multimodal imaging
Paper

A novel triphenylamine-BODIPY dendron: click synthesis, near-infrared emission and a multi-channel chemodosimeter for Hg2+ and Fe3+

A novel near-infrared emission triphenylamine-BODIPY dendron for Hg2+ and Fe3+ detection, fluorescent nanoparticle and living cell imaging.

Graphical abstract: A novel triphenylamine-BODIPY dendron: click synthesis, near-infrared emission and a multi-channel chemodosimeter for Hg2+ and Fe3+
Paper

Phase-changeable and bubble-releasing implants for highly efficient HIFU-responsive tumor surgery and chemotherapy

A multifunctional poly(lactic-co-glycolic acid) (PLGA)-based solid implant was constructed within a tumor for highly efficient HIFU-responsive tumor surgery and chemotherapy.

Graphical abstract: Phase-changeable and bubble-releasing implants for highly efficient HIFU-responsive tumor surgery and chemotherapy
Paper

Regulation of local bone remodeling mediated by hybrid multilayer coating embedded with hyaluronan-alendronate/BMP-2 nanoparticles on Ti6Al7Nb implants

Hyaluronate-alendronate/BMP-2 nanoparticles were inserted into Gel/Chi multilayers on Ti6Al7Nb for enhancing BMP-2 stability and promoting local osteogenesis under osteoporosis.

Graphical abstract: Regulation of local bone remodeling mediated by hybrid multilayer coating embedded with hyaluronan-alendronate/BMP-2 nanoparticles on Ti6Al7Nb implants
Paper

Regulation of the growth, morphology, mechanical properties and biocompatibility of natural polysaccharide-based multilayers by Hofmeister anions

Herein the optimization of the physicochemical properties and surface biocompatibility of polyelectrolyte multilayers of the natural, biocompatible and biodegradable, linear polysaccharides hyaluronan and chitosan by Hofmeister anions was systematically investigated.

Graphical abstract: Regulation of the growth, morphology, mechanical properties and biocompatibility of natural polysaccharide-based multilayers by Hofmeister anions
Paper

Covalent crosslinking of graphene oxide and carbon nanotube into hydrogels enhances nerve cell responses

Chemically crosslinking GOa and CNTpega followed by in situ reduction fabricated a conductive rGOa–CNTpega–OPF hydrogel that strongly stimulated neurite growth.

Graphical abstract: Covalent crosslinking of graphene oxide and carbon nanotube into hydrogels enhances nerve cell responses
Paper

Overcoming ABCG2-mediated multidrug resistance by a mineralized hyaluronan–drug nanocomplex

A multicomponent nanocomplex generated by hyaluronan-based biomineralization was successfully employed to combat ABCG2-mediated multidrug resistance.

Graphical abstract: Overcoming ABCG2-mediated multidrug resistance by a mineralized hyaluronan–drug nanocomplex
Paper

Synthesis of EDTA-assisted CeVO4 nanorods as robust peroxidase mimics towards colorimetric detection of H2O2

CeVO4 nanorods were developed as novel, simple and highly sensitive biomimetic catalysts and used for colorimetric detection of H2O2.

Graphical abstract: Synthesis of EDTA-assisted CeVO4 nanorods as robust peroxidase mimics towards colorimetric detection of H2O2
Paper

Competitive ligand exchange of crosslinking ions for ionotropic hydrogel formation

We describe a new approach to form hydrogels of ionotropic polymers using competitive displacement of chelated ions. This strategy enables control of ion release kinetics within an aqueous polymer solution and thus control over gelation kinetics across a wide range of pH.

Graphical abstract: Competitive ligand exchange of crosslinking ions for ionotropic hydrogel formation
Paper

Graphene oxide nanohybrid that photoreleases nitric oxide

Covalent functionalization of graphene oxide with a suitable NO photodonor leads to a nanohybrid material that releases NO under visible light and has potential applications in biomedical research.

Graphical abstract: Graphene oxide nanohybrid that photoreleases nitric oxide
Paper

A comparative study of the mechanical properties of hybrid double-network hydrogels in swollen and as-prepared states

Significant efforts have been made to develop very tough hydrogels at both swelling and as-prepared states towards many scientific and industrial applications.

Graphical abstract: A comparative study of the mechanical properties of hybrid double-network hydrogels in swollen and as-prepared states
Paper

A gold nanostar based multi-functional tumor-targeting nanoplatform for tumor theranostic applications

A gold nanostar based multi-functional tumor-targeting nanoplatform (DOX/GNSTs–PEG/PEI–FA) for tumor theranostic applications.

Graphical abstract: A gold nanostar based multi-functional tumor-targeting nanoplatform for tumor theranostic applications
Paper

Electron transfer driven highly valent silver for chronic wound treatment

This paper shows that reducing the dose of silver, additionally conferring electron transfer potential, could simultaneously achieve good biocompatibility and strong bactericidal ability without introducing extra chemical residuals for chronic wound treatment.

Graphical abstract: Electron transfer driven highly valent silver for chronic wound treatment
Paper

Preparation of gelatin/Fe3O4 composite scaffolds for enhanced and repeatable cancer cell ablation

Gelatin/Fe3O4 composite scaffolds with controlled pore structures were prepared by a facile ice particulate templating method and they showed great potential for near-infrared photothermal cancer therapy.

Graphical abstract: Preparation of gelatin/Fe3O4 composite scaffolds for enhanced and repeatable cancer cell ablation
Paper

Engineering DN hydrogels from regenerated silk fibroin and poly(N-vinylcaprolactam)

The development of biocompatible hydrogels that possess adequate elasticity and toughness to withstand mechanically active environments, remains a significant challenge for tissue engineering applications. In this study, a family of silk-based double network hydrogels have been fabricated that display elasticity closer to native cartilage.

Graphical abstract: Engineering DN hydrogels from regenerated silk fibroin and poly(N-vinylcaprolactam)
Paper

A robust double-network hydrogel with under sea water superoleophobicity fabricated via one-pot, one-step reaction

A robust double-network (DN) hydrogel fabricated by a one-pot, one-step reaction is reported.

Graphical abstract: A robust double-network hydrogel with under sea water superoleophobicity fabricated via one-pot, one-step reaction
Paper

Dual responsive mesoporous silica nanoparticles for targeted co-delivery of hydrophobic and hydrophilic anticancer drugs to tumor cells

Dual responsive mesoporous silica nanoparticles integrating stepwise tumor targeting and co-delivery of multiple anticancer drugs were developed to attenuate the drug resistance of cancer cells.

Graphical abstract: Dual responsive mesoporous silica nanoparticles for targeted co-delivery of hydrophobic and hydrophilic anticancer drugs to tumor cells
Paper

Surface modification with E-cadherin fusion protein for mesenchymal stem cell culture

To effectively expand human mesenchymal stem cells (hMSCs) in vitro without affecting their innate biological properties, a fusion protein (hE-cad-Fc) was fabricated and used as a biomimetic matrix for MSC culture surface modification.

Graphical abstract: Surface modification with E-cadherin fusion protein for mesenchymal stem cell culture
Paper

Nanostrontium ranelate incorporated injectable hydrogel enhanced matrix production supporting chondrogenesis in vitro

An injectable strontium ranelate nanoparticle-loaded composite gel provides a required environment for chondrogenesis, supplemented with the controlled release of strontium ranelate.

Graphical abstract: Nanostrontium ranelate incorporated injectable hydrogel enhanced matrix production supporting chondrogenesis in vitro
Paper

Facile fabrication of amphiphilic AIE active glucan via formation of dynamic bonds: self assembly, stimuli responsiveness and biological imaging

A one-pot strategy has been developed for the preparation of stimuli responsive AIE active glucan through formation of a dynamic Schiff base and a phenyl borate.

Graphical abstract: Facile fabrication of amphiphilic AIE active glucan via formation of dynamic bonds: self assembly, stimuli responsiveness and biological imaging
Paper

Azo-functionalized Fe3O4 nanoparticles: a near-infrared light triggered drug delivery system for combined therapy of cancer with low toxicity

A smart drug delivery system based on thermo-sensitive molecule was designed. When exposed to near infrared (NIR) light, Fe3O4 nanoparticles transfer the light to heat rapidly, leading to the cleavage of the Azo linker and the release of DOX.

Graphical abstract: Azo-functionalized Fe3O4 nanoparticles: a near-infrared light triggered drug delivery system for combined therapy of cancer with low toxicity
Paper

Soy protein-directed one-pot synthesis of gold nanomaterials and their functional conductive devices

Gold nanomaterials were synthesized via a facile and green method, using soy protein isolate as reductant, template, and capping agent.

Graphical abstract: Soy protein-directed one-pot synthesis of gold nanomaterials and their functional conductive devices
Paper

Laminar ventricular myocardium on a microelectrode array-based chip

Micromolded gelatin can be used to engineer laminar human myocardium on microelectrode array chips for electrophysiological studies and drug testing.

Graphical abstract: Laminar ventricular myocardium on a microelectrode array-based chip
Paper

Development of a cell delivery system using alginate microbeads for tissue regeneration

Alginate microbeads incorporating adipose-derived stem cells (ASCs) have potential for delivering viable cells capable of facilitating tissue regeneration.

Graphical abstract: Development of a cell delivery system using alginate microbeads for tissue regeneration
Paper

“Stealthy” chitosan/mesoporous silica nanoparticle based complex system for tumor-triggered intracellular drug release

A pH- and redox-sensitive “stealthy” chitosan/mesoporous silica nanoparticle-based complex system is prepared for tumor-triggered intracellular drug release.

Graphical abstract: “Stealthy” chitosan/mesoporous silica nanoparticle based complex system for tumor-triggered intracellular drug release
Paper

Tunable self-assembly of Irinotecan-fatty acid prodrugs with increased cytotoxicity to cancer cells

A small library of Irinotecan-fatty acid prodrugs which can self-assemble into different nanostructures is constructed to achieve enhanced cytotoxicity.

Graphical abstract: Tunable self-assembly of Irinotecan-fatty acid prodrugs with increased cytotoxicity to cancer cells
Paper

The synergetic effect of nano-structures and silicon-substitution on the properties of hydroxyapatite scaffolds for bone regeneration

Control over the morphology and chemical composition of hydroxyapatite (HAp) bioceramic scaffolds is of great importance for their applications.

Graphical abstract: The synergetic effect of nano-structures and silicon-substitution on the properties of hydroxyapatite scaffolds for bone regeneration
Paper

Anticoagulant sodium alginate sulfates and their mussel-inspired heparin-mimetic coatings

We synthesized novel sodium alginate sulfates (SASs) with different sulfation degrees. All the SASs, DA-g-SASs, and coated substrates had good anticoagulant properties and biocompatibilit.

Graphical abstract: Anticoagulant sodium alginate sulfates and their mussel-inspired heparin-mimetic coatings
Paper

Diblock- and triblock-copolymer based mixed micelles with high tumor penetration in vitro and in vivo

A series of self-assembled mixed micelles composed of TPGS and Pluronics were fabricated and their cellular uptake and exocytosis behaviors were studied in 2D cell and 3D tumor spheroid models.

Graphical abstract: Diblock- and triblock-copolymer based mixed micelles with high tumor penetration in vitro and in vivo
Paper

Microgels with tunable affinity-controlled protein release via desolvation of self-assembled peptide nanofibers

We demonstrate an approach to fabricate microgels from self-assembled peptide nanofibers via desolvation. Proteins can be co-desolvated with nanofibers to create protein-loaded microgels. Modifying nanofibers with a protein-binding ligand provides tunable affinity-controlled protein release.

Graphical abstract: Microgels with tunable affinity-controlled protein release via desolvation of self-assembled peptide nanofibers
Open Access Paper

Microfluidically fabricated pH-responsive anionic amphiphilic microgels for drug release

Novel amphiphilic microgels with hydrophobic and hydrophilic monomer units on the polymer chains were fabricated with an on-chip polymerisation methodology using a novel chip design.

Graphical abstract: Microfluidically fabricated pH-responsive anionic amphiphilic microgels for drug release
Paper

Targeting mitochondrial DNA with a two-photon active Ru(II) phenanthroline derivative

A novel phenanthroline Ru(II) derivative for targeting mitochondrial DNA was designed and its potential applications in biological processes were highlighted.

Graphical abstract: Targeting mitochondrial DNA with a two-photon active Ru(ii) phenanthroline derivative
Paper

3D-printed bioceramic scaffolds with a Fe3O4/graphene oxide nanocomposite interface for hyperthermia therapy of bone tumor cells

Magnetic scaffolds display prominent magnetothermal ability, and can effectively kill tumor cells in an alternating magnetic field and improve bone formation ability in vitro.

Graphical abstract: 3D-printed bioceramic scaffolds with a Fe3O4/graphene oxide nanocomposite interface for hyperthermia therapy of bone tumor cells
Paper

A multifunctional core–shell nanoplatform for enhanced cancer cell apoptosis and targeted chemotherapy

A novel multifunctional nanoplatform was designed based on the combination of silver nanoparticles (AgNPs) with nucleolin-targeted and doxorubicin (Dox)-loaded manganese dioxide (MnO2) nanosheets to induce enhanced cancer cell apoptosis and targeted chemotherapy.

Graphical abstract: A multifunctional core–shell nanoplatform for enhanced cancer cell apoptosis and targeted chemotherapy
Paper

Tracking translocation of glucan microparticles targeting M cells: implications for oral drug delivery

Model glucan microparticles (GMs) targeting M cells are employed to track translocation through M cell pathways as well as to various organs via the systemic circulation.

Graphical abstract: Tracking translocation of glucan microparticles targeting M cells: implications for oral drug delivery
Paper

Disulfide-crosslinked albumin hydrogels

Albumin hydrogels crosslinked by disulfide bonds between the protein's own thiol groups.

Graphical abstract: Disulfide-crosslinked albumin hydrogels
Paper

Mussel-inspired coatings on Ag nanoparticle-conjugated carbon nanotubes: bactericidal activity and mammal cell toxicity

Silver nanoparticle (AgNP)-based nanohybrids have been proposed as efficient antimicrobial agents because of their robust bactericidal activity.

Graphical abstract: Mussel-inspired coatings on Ag nanoparticle-conjugated carbon nanotubes: bactericidal activity and mammal cell toxicity
Paper

Surface functionalized halloysite nanotubes decorated with silver nanoparticles for enzyme immobilization and biosensing

Illustrating the selective modification of the HNTs for the incorporation of AgNPs and site-specific covalent immobilization of the GOx enzymes.

Graphical abstract: Surface functionalized halloysite nanotubes decorated with silver nanoparticles for enzyme immobilization and biosensing
Paper

A novel multifunctional biomimetic Au@BSA nanocarrier as a potential siRNA theranostic nanoplatform

A novel siRNA nanocarrier based on biomimetic Au@BSA nanoflowers is fabricated which could serve as a potential theranostic nanoplatform.

Graphical abstract: A novel multifunctional biomimetic Au@BSA nanocarrier as a potential siRNA theranostic nanoplatform
Paper

Synthesis of a three-layered SiO2@Au nanoparticle@polyaniline nanocomposite and its application in simultaneous electrochemical detection of uric acid and ascorbic acid

A novel three-layered SiO2@AuNP@PANI nanocomposite was synthesized and adopted for the simultaneous electrochemical determination of uric acid and ascorbic acid.

Graphical abstract: Synthesis of a three-layered SiO2@Au nanoparticle@polyaniline nanocomposite and its application in simultaneous electrochemical detection of uric acid and ascorbic acid
Paper

The stimulation of osteogenic differentiation of embryoid bodies from human induced pluripotent stem cells by akermanite bioceramics

We report the stimulation of osteogenic differentiation of embryoid body (EB) cells derived from human induced pluripotent stem cells (iPSCs) by akermanite bioceramics.

Graphical abstract: The stimulation of osteogenic differentiation of embryoid bodies from human induced pluripotent stem cells by akermanite bioceramics
Paper

Phosphorylated poly(sebacoyl diglyceride) – a phosphate functionalized biodegradable polymer for bone tissue engineering

This study demonstrates a simply powerful way to make therapeutic materials: using small functional units (phosphates) to control bioactivity (osteogenesis).

Graphical abstract: Phosphorylated poly(sebacoyl diglyceride) – a phosphate functionalized biodegradable polymer for bone tissue engineering
Paper

Epitope imprinting enhanced IMAC (EI-IMAC) for highly selective purification of His-tagged protein

Selectivity of epitope imprinted sites is introduced on the IMAC surface through epitope surface imprinting. The obtained epitope imprinting enhanced IMAC (EI-IMAC) could purify His-tagged proteins with high selectivity without any major interference from the host proteins.

Graphical abstract: Epitope imprinting enhanced IMAC (EI-IMAC) for highly selective purification of His-tagged protein
Paper

MMP-responsive theranostic nanoplatform based on mesoporous silica nanoparticles for tumor imaging and targeted drug delivery

A novel mesoporous silica-based multifunctional theranostic nanoplatform was reported, which can not only achieve MMP-2-activated fluorescence imaging, but also realize tumor targeted drug delivery and drug release indicating.

Graphical abstract: MMP-responsive theranostic nanoplatform based on mesoporous silica nanoparticles for tumor imaging and targeted drug delivery
Paper

Characterisation of nanoscale carbide precipitation in as-cast Co–Cr–W-based dental alloys

The results of the present study indicate the importance of local chemistry along with carbide precipitation in the optimization of alloy design for achieving desirable properties such as high strength, ductility, and corrosion resistance in dental Co–Cr-based cast alloys.

Graphical abstract: Characterisation of nanoscale carbide precipitation in as-cast Co–Cr–W-based dental alloys
Paper

Functionalizing micro-3D-printed protein hydrogels for cell adhesion and patterning

A versatile and dynamic photoconjugation platform is introduced that provides high, 3D spatial resolution for functionalizing micro-3D-printed (μ-3DP) hydrogels. Schwann cells are patterned on μ-3DP hydrogels precisely labeled with RGD, a cell adhesive peptide, demonstrating utility of this platform for cell culture applications.

Graphical abstract: Functionalizing micro-3D-printed protein hydrogels for cell adhesion and patterning
Paper

Three label-free thrombin aptasensors based on aptamers and [Ru(bpy)2(o-mopip)]2+

The label free aptasensor based on an aptamer pair and [Ru(bpy)2(o-mopip)]2+–GO has been successfully applied to sandwich assays for thrombin detection.

Graphical abstract: Three label-free thrombin aptasensors based on aptamers and [Ru(bpy)2(o-mopip)]2+
Paper

Osmo-solidification of all-aqueous emulsion with enhanced preservation of protein activity

An “osmo-solidification” approach that solidifies all-aqueous emulsion droplets for encapsulating proteins with superior preservation of their activity.

Graphical abstract: Osmo-solidification of all-aqueous emulsion with enhanced preservation of protein activity
Paper

A large-deformation phase transition electrothermal actuator based on carbon nanotube–elastomer composites

Large actuation occurs while the closed water is boiled to steam at an induced heating power. A closed liquid circulation system based on two of these actuators can work like a real heart.

Graphical abstract: A large-deformation phase transition electrothermal actuator based on carbon nanotube–elastomer composites
Paper

Cellular endocytosis and trafficking of cholera toxin B-modified mesoporous silica nanoparticles

Mesoporous silica nanoparticles were functionalized with cholera toxin subunit B protein to influence their intracellular trafficking pathways.

Graphical abstract: Cellular endocytosis and trafficking of cholera toxin B-modified mesoporous silica nanoparticles
Paper

A highly specific graphene platform for sensing collagen triple helix

We have designed a dye-labeled, highly positively charged single stranded collagen (ssCOL) peptide probe whose adsorption into GO quenches its fluorescence. The hybridization of the ssCOL probe with a complementary target sequence forms a triple stranded collagen (tsCOL) peptide, resulting in the retention of the fluorescence of the probe.

Graphical abstract: A highly specific graphene platform for sensing collagen triple helix
Paper

Biomimetic gelatin methacrylamide hydrogel scaffolds for bone tissue engineering

The biomimetic GelMA scaffolds which have highly porous, interconnected macropores, and rough surface could promote ADSC to differentiate into osteoblasts and bone formation.

Graphical abstract: Biomimetic gelatin methacrylamide hydrogel scaffolds for bone tissue engineering
73 items - Showing page 1 of 2

About this collection

This on-going web collection features all the articles published in Journal of Materials Chemistry B in 2016 marked as HOT, as recommended by referees.  Congratulations to all the authors whose articles are featured!

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