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Themed collection Biosensors

47 items
Editorial

Introduction to Biosensors

Shaoqin Liu and Ning Gu, Journal of Materials Chemistry B themed issue on Biosensors.

Graphical abstract: Introduction to Biosensors
From the themed collection: Biosensors
Review Article

Assessing the range of enzymatic and oxidative tunability for biosensor design

This review aims to inspire novel biosensor design by addressing materials chemistries through the lense of enzymatic and oxidative susceptibility in the spectra of inflammatory disease biomarkers.

Graphical abstract: Assessing the range of enzymatic and oxidative tunability for biosensor design
Review Article

Enhanced biosensing strategies using electrogenerated chemiluminescence: recent progress and future prospects

An overview of enhancement strategies for highly sensitive ECL-based sensing of bioanalytes enabling early detection of cancer.

Graphical abstract: Enhanced biosensing strategies using electrogenerated chemiluminescence: recent progress and future prospects
Review Article

Nanomaterial-based biosensors for DNA methyltransferase assay

We review the recent advances in the development of nanomaterial-based biosensors for DNA methyltransferase assay.

Graphical abstract: Nanomaterial-based biosensors for DNA methyltransferase assay
Review Article

Stretchable and tough conductive hydrogels for flexible pressure and strain sensors

This review summarises recent advances in stretchable and tough conductive hydrogel sensors for wearable and implantable devices.

Graphical abstract: Stretchable and tough conductive hydrogels for flexible pressure and strain sensors
Review Article

Nanomaterial-based gas sensors used for breath diagnosis

Gas-sensing applications commonly use nanomaterials (NMs) because of their unique physicochemical properties, including a high surface-to-volume ratio, enormous number of active sites, controllable morphology, and potential for miniaturisation.

Graphical abstract: Nanomaterial-based gas sensors used for breath diagnosis
Review Article

Aptamer-based nanostructured interfaces for the detection and release of circulating tumor cells

This paper summarizes various aptamer-functionalized nanostructured interfaces for the detection and release of circulating tumor cells.

Graphical abstract: Aptamer-based nanostructured interfaces for the detection and release of circulating tumor cells
Review Article

Wearable biochemical sensors for human health monitoring: sensing materials and manufacturing technologies

Recent achievements and challenges in materials and manufacturing technologies of sensing electrodes in wearable biosensors have been highlighted.

Graphical abstract: Wearable biochemical sensors for human health monitoring: sensing materials and manufacturing technologies
Review Article

Genetically encoded light-up RNA aptamers and their applications for imaging and biosensing

Light-up RNA aptamers and their applications in bioimaging and biosensing of small ligands and biomacromolecules are described.

Graphical abstract: Genetically encoded light-up RNA aptamers and their applications for imaging and biosensing
Review Article

From design to applications of stimuli-responsive hydrogel strain sensors

Stimuli-responsive hydrogel strain sensors that synergize the advantages of both hydrogel and smart functional materials have attracted increasing interest from material design to emerging applications in health monitors and human–machine interfaces.

Graphical abstract: From design to applications of stimuli-responsive hydrogel strain sensors
Review Article

Recent development of biofuel cell based self-powered biosensors

BFC-based SPBs have been used as power sources for other devices and as sensors for detecting toxicity and BOM.

Graphical abstract: Recent development of biofuel cell based self-powered biosensors
Review Article

Advances in functional nucleic acid based paper sensors

This article provides an extensive review of paper-based sensors that utilize functional nucleic acids, particularly DNA aptamers and DNAzymes, as recognition elements.

Graphical abstract: Advances in functional nucleic acid based paper sensors
Review Article

Recent advances of tissue-interfaced chemical biosensors

This review discusses recent advances of tissue interfaced chemical biosensors, highlights current challenges and gives an outlook on future possibilities.

Graphical abstract: Recent advances of tissue-interfaced chemical biosensors
Review Article

Aggregation-induced emission luminogens for RONS sensing

The development of AIE bioprobes for RONS sensing in living systems is now summarized. We discuss some representative examples of AIEgen based bioprobes in terms of their molecular design, sensing mechanism and sensitive sensing in vitro and in vivo.

Graphical abstract: Aggregation-induced emission luminogens for RONS sensing
Review Article

An efficient strategy for circulating tumor cell detection: surface-enhanced Raman spectroscopy

Circulating tumor cells (CTCs) are circulating cancer cells that shed from tumor tissue into blood vessels and circulate in the blood to invade other organs, which results in fatal metastases. Surface-enhanced Raman scattering (SERS) has great potentials in CTCs detection.

Graphical abstract: An efficient strategy for circulating tumor cell detection: surface-enhanced Raman spectroscopy
Review Article

Controlled/“living” radical polymerization-based signal amplification strategies for biosensing

Controlled/“living” radical polymerization-based signal amplification strategies and their applications in highly sensitive biosensing of clinically relevant biomolecules are reviewed.

Graphical abstract: Controlled/“living” radical polymerization-based signal amplification strategies for biosensing
Review Article

Emerging intraoral biosensors

Intraoral biosensors are emerging as reliable medical devices for non-invasive health-care monitoring.

Graphical abstract: Emerging intraoral biosensors
Review Article

Multi-emission metal–organic framework composites for multicomponent ratiometric fluorescence sensing: recent developments and future challenges

Ratiometric fluorescence sensors that are achieved via the ratiometric fluorescence intensity changes of emission peaks based on multi-emission fluorescence probes show a huge advantage.

Graphical abstract: Multi-emission metal–organic framework composites for multicomponent ratiometric fluorescence sensing: recent developments and future challenges
Review Article

Biosensors and bioassays for determination of matrix metalloproteinases: state of the art and recent advances

This review highlights the recent advances in nanomaterial-based immunoassays for MMP abundance measurements and nanomaterial-based biosensors for MMP activity determination.

Graphical abstract: Biosensors and bioassays for determination of matrix metalloproteinases: state of the art and recent advances
Review Article

Luminescence approaches for the rapid detection of disease-related receptor proteins using transition metal-based probes

Abnormally expressed receptor proteins are proved to be one of the crucial biomarkers for specific human diseases. Transitional metal based strategies possess delightful strengths in the in-field and real-time visualization of receptor proteins.

Graphical abstract: Luminescence approaches for the rapid detection of disease-related receptor proteins using transition metal-based probes
Communication

Simulation-directed amplifiable nanoparticle enhanced quantitative scattering assay under low magnification dark field microscopy

A tunable linker-based signal amplification strategy yielding 6-fold enhanced sensitivity for low magnification dark-field quantitative assays.

Graphical abstract: Simulation-directed amplifiable nanoparticle enhanced quantitative scattering assay under low magnification dark field microscopy
From the themed collection: Biosensors
Communication

Ti3C2Tx MXene-derived TiO2/C-QDs as oxidase mimics for the efficient diagnosis of glutathione in human serum

A Ti3C2Tx MXene-derived TiO2/C-QD oxidase mimic was developed and used for the efficient diagnosis of glutathione in human serum.

Graphical abstract: Ti3C2Tx MXene-derived TiO2/C-QDs as oxidase mimics for the efficient diagnosis of glutathione in human serum
From the themed collection: Biosensors
Communication

A dual-targeted CeO2–DNA nanosensor for real-time imaging of H2O2 to assess atherosclerotic plaque vulnerability

A novel dual-targeted CeO2–DNA nanosensor by modifying with folic acid (FA) and CD36 antibody was designed.

Graphical abstract: A dual-targeted CeO2–DNA nanosensor for real-time imaging of H2O2 to assess atherosclerotic plaque vulnerability
From the themed collection: Biosensors
Communication

Platinum ions mediate the interactions between DNA and carbon quantum dots: diagnosis of MRSA infections

The isothermal amplification products of mecA and femA genes induce the fluorescence quenching of platinum ions-capped carbon quantum dots to allow the specific identification of methicillin-resistant Staphylococcus aureus.

Graphical abstract: Platinum ions mediate the interactions between DNA and carbon quantum dots: diagnosis of MRSA infections
From the themed collection: Biosensors
Paper

Optical nanogap antennas as plasmonic biosensors for the detection of miRNA biomarkers

Gold nanogap antennas fabricated by hole-mask colloidal lithography as sensitive substrates for plasmonic biosensing.

Graphical abstract: Optical nanogap antennas as plasmonic biosensors for the detection of miRNA biomarkers
From the themed collection: Biosensors
Paper

Toehold-regulated competitive assembly to accelerate the kinetics of graphene oxide-based biosensors

With toehold-regulation, the kinetics of graphene oxide-based biosensors can be accelerated.

Graphical abstract: Toehold-regulated competitive assembly to accelerate the kinetics of graphene oxide-based biosensors
From the themed collection: Biosensors
Paper

A perylenetetracarboxylic dianhydride and aniline-assembled supramolecular nanomaterial with multi-color electrochemiluminescence for a highly sensitive label-free immunoassay

A novel multi-color ECL nanomaterial assembled from 3,4,9,10-perylenetetracarboxylic dianhydride (PTCDA) and aniline (An) was used for highly sensitive label-free CEA detection.

Graphical abstract: A perylenetetracarboxylic dianhydride and aniline-assembled supramolecular nanomaterial with multi-color electrochemiluminescence for a highly sensitive label-free immunoassay
From the themed collection: Biosensors
Paper

Novel perylene probe-encapsulated metal–organic framework nanocomposites for ratiometric fluorescence detection of ATP

Schematic illustration of PDI@ZIF-8 nanocomposite synthesis and ratiometric fluorescence assay for ATP sensing. 2-MIm: 2-methylimidazole.

Graphical abstract: Novel perylene probe-encapsulated metal–organic framework nanocomposites for ratiometric fluorescence detection of ATP
From the themed collection: Biosensors
Paper

Silver nanoprism-based plasmonic ELISA for sensitive detection of fluoroquinolones

Silver nanoprism-based plasmonic ELISA for qualitative and quantitative detection of fluoroquinolones.

Graphical abstract: Silver nanoprism-based plasmonic ELISA for sensitive detection of fluoroquinolones
From the themed collection: Biosensors
Paper

Structurally coloured contact lens sensor for point-of-care ophthalmic health monitoring

A structurally coloured contact lens sensor has been developed for point-of-care diagnosis of eye diseases.

Graphical abstract: Structurally coloured contact lens sensor for point-of-care ophthalmic health monitoring
From the themed collection: Biosensors
Paper

Flexible and stretchable dual mode nanogenerator for rehabilitation monitoring and information interaction

Sensors with flexibility and stretchability are the key functional modules of converter between mechanical motions and electric signals for intelligent robots and rehabilitation training systems.

Graphical abstract: Flexible and stretchable dual mode nanogenerator for rehabilitation monitoring and information interaction
From the themed collection: Biosensors
Paper

Boosting biomolecular interactions through DNA origami nano-tailored biosensing interfaces

Nano-tailored DNA origami designs nanostructure the bioreceptor layer of encoded microparticles in an innovative microfluidic platform, hereby boosting biomolecular interactions.

Graphical abstract: Boosting biomolecular interactions through DNA origami nano-tailored biosensing interfaces
From the themed collection: Biosensors
Paper

Nucleoside-based fluorescent carbon dots for discrimination of metal ions

Using nucleosides and citrate as starting materials, a series of fluorescent carbon dots were synthesized showing different quenching properties by metal ions for their detection by a sensor array.

Graphical abstract: Nucleoside-based fluorescent carbon dots for discrimination of metal ions
From the themed collection: Biosensors
Paper

Glutamate detection at the cellular level by means of polymer/enzyme multilayer modified carbon nanoelectrodes

Carbon nanoelectrodes in the sub-micron range were modified with an enzyme cascade immobilized in a spatially separated polymer double layer system for the detection of glutamate at the cellular level.

Graphical abstract: Glutamate detection at the cellular level by means of polymer/enzyme multilayer modified carbon nanoelectrodes
From the themed collection: Biosensors
Paper

Stretchable gold fiber-based wearable electrochemical sensor toward pH monitoring

A stretchable gold fiber-based wearable electrochemical pH two-electrodes sensing system for human health monitoring.

Graphical abstract: Stretchable gold fiber-based wearable electrochemical sensor toward pH monitoring
From the themed collection: Biosensors
Paper

Biomolecular detection, tracking, and manipulation using a magnetic nanoparticle-quantum dot platform

Fluorescent and magnetic materials play a significant role in biosensor technology, enabling sensitive quantification and separations with applications in diagnostics, purification, quality control, and therapeutics.

Graphical abstract: Biomolecular detection, tracking, and manipulation using a magnetic nanoparticle-quantum dot platform
From the themed collection: Biosensors
Paper

Graphene–nucleic acid biointerface-engineered biosensors with tunable dynamic range

Programmed biosensors with tunable quantification range and higher specificity have been constructed by engineering graphene–nucleic acid biointerfaces.

Graphical abstract: Graphene–nucleic acid biointerface-engineered biosensors with tunable dynamic range
From the themed collection: Biosensors
Paper

Electrodeposition of nickel nanostructures using silica nanochannels as confinement for low-fouling enzyme-free glucose detection

This work reports an enzyme-free glucose sensor based on nickel nanostructures electrodeposited on a fluorine-doped tin oxide (FTO) electrode modified with a silica nanochannel membrane (SNM).

Graphical abstract: Electrodeposition of nickel nanostructures using silica nanochannels as confinement for low-fouling enzyme-free glucose detection
From the themed collection: Biosensors
Paper

Highly efficient electrochemiluminescence of ruthenium complex-functionalized CdS quantum dots and their analytical application

Highly efficient electrochemiluminescence of ruthenium complex-functionalized CdS quantum dots via ECL resonance energy transfer (ECL-RET) and their analytical application.

Graphical abstract: Highly efficient electrochemiluminescence of ruthenium complex-functionalized CdS quantum dots and their analytical application
From the themed collection: Biosensors
Paper

A paper-based SERS assay for sensitive duplex cytokine detection towards the atherosclerosis-associated disease diagnosis

Novel SERS based sensing assay was built by combining nanoporous membrane with sandwich immunoassay for duplex cytokines detection. It can be used as a promising candidate for clinical application due to its excellent performance in human serum.

Graphical abstract: A paper-based SERS assay for sensitive duplex cytokine detection towards the atherosclerosis-associated disease diagnosis
From the themed collection: Biosensors
Paper

Ultrasensitive self-enhanced electrochemiluminescence sensor based on novel PAN@Ru@PEI@Nafion nanofiber mat

A novel self-enhanced electrochemiluminescence nanofiber mat was for the first time prepared by one-step electrospinning a mixture of polyacrylonitrile, Ru(bpy)32+, poly(ethylenimine) and Nafion.

Graphical abstract: Ultrasensitive self-enhanced electrochemiluminescence sensor based on novel PAN@Ru@PEI@Nafion nanofiber mat
From the themed collection: Biosensors
Paper

A single-liquid miniature biofuel cell with boosting power density via gas diffusion bioelectrodes

A single-liquid glucose–O2 cell is constructed by gas diffusion electrode. O2 diffusion directly from air to active sites of enzyme enhances the enzymatic reaction rate. The maximum power output density of the cell is 53 μW cm−2.

Graphical abstract: A single-liquid miniature biofuel cell with boosting power density via gas diffusion bioelectrodes
From the themed collection: Biosensors
Paper

Turn-on fluorescent glutathione detection based on lucigenin and MnO2 nanosheets

A GSH sensing platform using lucigenin as a fluorescent probe in the presence of MnO2 nanosheets was reported for the first time.

Graphical abstract: Turn-on fluorescent glutathione detection based on lucigenin and MnO2 nanosheets
From the themed collection: Biosensors
Paper

Functionalized tungsten disulfide nanotubes for dopamine and catechol detection in a tyrosinase-based amperometric biosensor design

Functionalized tungsten disulfide nanotubes were evaluated as an enzyme support for electrochemical biosensors.

Graphical abstract: Functionalized tungsten disulfide nanotubes for dopamine and catechol detection in a tyrosinase-based amperometric biosensor design
From the themed collection: Biosensors
Paper

A self-assembled RNA-triple helix hydrogel drug delivery system targeting triple-negative breast cancer

A novel RNA-triple-helix hydrogel for treatment of triple negative breast cancers (TNBCs) by incorporating RNA-triple-helix and siRNA duplexes of CXCR4 into the same RNA nanoparticles was developed, without the synthetic polycationic reagents.

Graphical abstract: A self-assembled RNA-triple helix hydrogel drug delivery system targeting triple-negative breast cancer
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

A colorimetric and electrochemical dual-mode biosensor for thrombin using a magnetic separation technique

A colorimetric and electrochemical dual-mode biosensor for thrombin based on the combination of a magnetic separation technique and a signal amplification strategy.

Graphical abstract: A colorimetric and electrochemical dual-mode biosensor for thrombin using a magnetic separation technique
From the themed collection: Biosensors
Paper

Biotinylated and fluorophore-incorporated polymeric mixed micelles for tumor cell-specific turn-on fluorescence imaging of Al3+

We construct tumor-targeting fluorescent mixed nano-micelles for tumor cell-specific turn-on fluorescence imaging of Al3+.

Graphical abstract: Biotinylated and fluorophore-incorporated polymeric mixed micelles for tumor cell-specific turn-on fluorescence imaging of Al3+
From the themed collection: Biosensors
47 items

About this collection

Guest edited by Shaoqin Liu (Harbin Institute of Technology) and Ning Gu (Southeast University).

In the last couple of decades, a broad range of materials, including organic small molecules, inorganic materials, hydrogels, hybrids, or emerging nanomaterials and structures, have been proposed for the biosensors, skin-like electronics, implantable electronics, medicine diagnosis and monitoring, and so on. These new materials results in numerous new methods and techniques. These technologies have shown great advantages over conventional assays, particularly in sensitivity, selectivity, and practicality.

This themed issue in Journal of Materials Chemistry B aims to explore the latest developments in the materials design and synthesis, novel design and function of biosensors and bioelectronics, and potential applications for healthcare and biomedicine diagnosis.

Spotlight

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