Themed collection Chemistry for Medicine: Special Collection for RSC Advances
Anti-bacterial surfaces: natural agents, mechanisms of action, and plasma surface modification
This article reviews antibacterial surface strategies based on reactive plasma chemistry, focusing on how plasma-assisted processing of natural antimicrobial agents can produce antifouling and antibacterial materials for biomedical devices.
Bioapplication of graphene oxide derivatives: drug/gene delivery, imaging, polymeric modification, toxicology, therapeutics and challenges
This review article summarizes the latest progress in research regarding bioapplications of graphene oxide derivatives and provides expert opinions on strategies for overcoming the current challenges.
Metal-free domino one-pot protocols for quinoline synthesis
Metal-free domino one-pot protocols for quinoline synthesis have been reviewed.
Recent advances in crosslinking chemistry of biomimetic poly(ethylene glycol) hydrogels
This article reviews recent advances in the crosslinking chemistries of biomimetic hydrogels prepared from PEG-based macromers.
Plasmon-enhanced light harvesting: applications in enhanced photocatalysis, photodynamic therapy and photovoltaics
This review article summarizes the recent progress on surface plasmon-enhanced light harvesting and its applications toward enhanced photocatalysis, photodynamic therapy, chemical transformations and photovoltaics.
Gallic acid: a versatile antioxidant with promising therapeutic and industrial applications
Oxidative stress, a result of an overproduction and accumulation of free radicals, is the leading cause of several degenerative diseases such as cancer, atherosclerosis, cardiovascular diseases, ageing and inflammatory diseases.
Modified biopolymer-dextrin based crosslinked hydrogels: application in controlled drug delivery
This review describes hydrogels and their classifications along with the synthesis and properties of biopolymer-dextrin based crosslinked hydrogels towards potential application in controlled drug delivery.
Toward point-of-care diagnostics with consumer electronic devices: the expanding role of nanoparticles
A review of the role that nanoparticles can play in point-of-care diagnostics that utilize consumer electronic devices such as cell phones and smartphones for readout, including an overview of important concepts and examples from the literature.
Fluorescent graphene quantum dots for biosensing and bioimaging
Graphene quantum dots with unique properties have great potential applications for biosensing and bioimaging.
Understanding cancer and the anticancer activities of naphthoquinones – a review
Naphthoquinone moieties are present in drugs such as doxorubicin which are used clinically to treat solid cancers.
Biological and pharmacological activities of amaryllidaceae alkaloids
This review discusses the recent developments on biological and pharmacological activities of amaryllidaceae alkaloids with IC50 or EC50 values since 2005, supporting the potential therapeutic possibilities for the use of these compounds.
Pyrrole: a resourceful small molecule in key medicinal hetero-aromatics
Pyrrole is widely known as a biologically active scaffold which possesses a diverse nature of activities.
Recent advances in the synthesis, characterization, and biomedical applications of ultrasmall thiolated silver nanoclusters
Recent advances in characterizing ultrasmall thiolated Ag nanoclusters, showing their optical and biological properties, and size, composition, and structure information.
Synthetic methodologies of achiral diarylmethanols, diaryl and triarylmethanes (TRAMs) and medicinal properties of diaryl and triarylmethanes-an overview
This review covers the synthesis of achiral diarylmethanols, diaryl and triarylmethanes and the bioactivities of diaryl and triarylmethanes during 1995 to 2013.
Bioimaging based on fluorescent carbon dots
Herein, we review the bioimaging application of three kinds of fluorescent carbon dots (CDs), namely, graphene quantum dots (GQDs), carbon nanodots (CNDs) and polymer dots (PDs).
Recent advances in the synthesis of quinolines: a review
This review article gives information about the recent advances in the synthesis of quinoline derivatives by various eco-friendly, green and clean protocols.
Mesoporous silica-based nanodevices for biological applications
This review highlights and addresses issues related to research on the development of mesoporous silica nanomaterials (MSNs) based nanodevices for biological applications.
Fabrication, modification, and biomedical applications of anodized TiO2 nanotube arrays
Recent research activities on the surface modification and biomedical applications of TiO2 NTAs are reviewed.
Polymeric micelles as drug delivery vehicles
Though much progress has been made in drug delivery systems, the design of a suitable carrier for the delivery of hydrophobic drugs is still a major challenge for researchers.
Nucleic acid therapeutics: basic concepts and recent developments
Nucleic acid based therapeutics comprising chemically modified oligonucleotides are the current focus of clinical research for the treatment of various diseases.
Mesoporous silica nanoparticles: importance of surface modifications and its role in drug delivery
This review considers the importance of surface modifications of mesoporous nanoparticles and their biological consequences.
Carbon-based quantum dots for fluorescence imaging of cells and tissues
On recent advances in the development of carbon-based quantum dots, carbon dots in particular, for fluorescence imaging of cells and tissues.
Curcumin, a promising anti-cancer therapeutic: a review of its chemical properties, bioactivity and approaches to cancer cell delivery
The chemical properties of curcumin as well as its proposed mechanism of action as an anti-cancer therapeutic are reviewed. Recent approaches to curcumin delivery are described.
Multi-functional fluorescent carbon dots with antibacterial and gene delivery properties
Dual-functionality carbon dots with both anti-microbial and gene transfection abilities were developed and their properties elaborated in this paper.
Alginate–peptide amphiphile core–shell microparticles as a targeted drug delivery system
We describe in this work the synthesis of microparticles with a doxorubicin drug conjugated alginate core and a shell of peptide amphiphile nanofibres functionalized for targeting the folate receptor.
Mesoporous silica nanoparticles enhance the cytotoxicity of curcumin
Curcumin encapsulated mesoporous silica nanoparticle (MSN) displaying higher cytotoxic for treatment in skin cancer cell line compared to pure curcumin.
PLA-based thermogel for the sustained delivery of chemotherapeutics in a mouse model of hepatocellular carcinoma
This work represents the first time that poly(PEG/PPG/PLA urethane) has been used for the delivery of drugs to tumours in vivo and the encouraging results point to the potential for further development of this thermogel platform for anti-cancer applications.
Safe and efficient membrane permeabilizing polymers based on PLLA for antibacterial applications
Highly active antibacterial poly(N,N-dimethylaminoethyl methacrylate)-block-poly(L-lactic acid)-block-poly(N,N-dimethylaminoethyl methacrylate) conjugated with poly(ethylene glycol) (D-PLLA-D@PEG) copolymers were synthesized.
Effects of the i-motif DNA loop on the fluorescence of silver nanoclusters
The loop sequences in i-motif DNA templates are well correlated with the fluorescence of the prepared Ag clusters.
Novel three-dimensional, conducting, biocompatible, porous, and elastic polyaniline-based scaffolds for regenerative therapies
Fabrication of two novel three-dimensional, conducting, biocompatible, porous, and elastic scaffolds composed of hyperbranched aliphatic polyesters, polyaniline, and poly(ε-caprolactone) for tissue engineering applications.
Design and development of a novel cellulose/γ-Fe2O3/Ag nanocomposite: a potential green catalyst and antibacterial agent
A new cellulose-based nanocomposite was synthesized, characterization and used for the synthesis of imidazoles and α-aminonitriles, and antibacterial property was investigated.
Osteoblastic cell responses and antibacterial efficacy of Cu/Zn co-substituted hydroxyapatite coatings on pure titanium using electrodeposition method
Effective physiological bone integration and absence of bacterial infection are essential for a successful orthopaedic or dental implant.
ZnO/Ag micro/nanospheres with enhanced photocatalytic and antibacterial properties synthesized by a novel continuous synthesis method
A continuous concentric impinging stream method was used for preparing ZnO/Ag MNSs, which possessed excellent photocatalytic and antibacterial activities.
Cyto and genotoxicities of graphene oxide and reduced graphene oxide sheets on spermatozoa
The interaction of graphene with spermatozoa resulted in trapping, oxidative stress, mitochondria damage, DNA damage and finally death of the spermatozoa.
Bifunctional TiO2/Ag3PO4/graphene composites with superior visible light photocatalytic performance and synergistic inactivation of bacteria
Schematic representation of the synthetic strategy for TiO2/Ag3PO4/GR composites.
Nanofibrous electroactive scaffolds from a chitosan-grafted-aniline tetramer by electrospinning for tissue engineering
Synthesis of chitosan–aniline tetramer and its electroactive nanofibrous scaffolds enhanced cell adhesion and proliferation of C2C12 myoblasts.
Aggregation-induced emission dye based luminescent silica nanoparticles: facile preparation, biocompatibility evaluation and cell imaging applications
Facile encapsulation of aggregation-induced emission dye into silica nanoparticles via a modified Stöber method was developed. Cell imaging applications of such luminescent silica nanoparticles were further investigated.
Size-controlled silver nanoparticles synthesized over the range 5–100 nm using the same protocol and their antibacterial efficacy
Size-specific antibacterial activity of 5–100 nm silver nanoparticles synthesized using a novel co-reduction approach.
PVDF film tethered with RGD-click-poly(glycidyl methacrylate) brushes by combination of direct surface-initiated ATRP and click chemistry for improved cytocompatibility
PVDF film was functionalized by grafting of RGD-click-poly(glycidyl methacrylate) brushes using the combination of direct surface-initiated ATRP and alkyne-azide click reaction for improved cell adhesion and proliferation.