Themed collection 2018 Green Chemistry Hot Articles
Key Green Chemistry research areas from a pharmaceutical manufacturers’ perspective revisited
The ACS Green Chemistry Institute® Pharmaceutical Roundtable has assembled an updated list of key research areas to highlight transformations and reaction media where more sustainable technologies would be most impactful.
A call to (green) arms: a rallying cry for green chemistry and engineering for CO2 capture, utilisation and storage
Chemists, engineers, scientists, lend us your ears… Carbon capture, utilisation, and storage (CCUS) is among the largest challenges on the horizon and we need your help.
Conservative evolution and industrial metabolism in Green Chemistry
Chemical substances and processes that play a fundamental role in the 12 principles of Green Chemistry representing conservative evolution and/or industrial metabolism were reviewed.
The Green ChemisTREE: 20 years after taking root with the 12 principles
A broad overview of the achievements and emerging areas in the field of Green Chemistry.
Decarboxylative reactions with and without light – a comparison
Carboxylic acids have gained more and more importance as versatile and renewable starting materials for the formation of platform molecules or high-value chemicals.
The reactions of dimethyl carbonate and its derivatives
The worldwide urge to embrace a sustainable and bio-compatible chemistry has led industry and academia to develop chlorine-free methodologies focused on the use of CO2-based compounds, such as dimethyl carbonate, as feedstocks, promoters and reaction media.
Automated and accelerated synthesis of indole derivatives on a nano-scale
Miniaturized and automated nanomole synthesis using acoustic dispensing technology dramatically accelerated the production of diverse libraries of three small molecule scaffolds.
Pd nanoparticles/polyoxometalate–ionic liquid composites on SiO2 as multifunctional catalysts for efficient production of ketones from diaryl ethers
Effective and selective transformation of diaryl ethers to value-added ketones.
Translating solid state organic synthesis from a mixer mill to a continuous twin screw extruder
A study on the translation of a solid-state fluorination reaction from a mechanochemical mixer-mill to a continuous twin-screw extruder is discussed herein.
Electrochemical oxidative radical oxysulfuration of styrene derivatives with thiols and nucleophilic oxygen sources
The first example of the electrochemical oxysulfuration reaction of alkenes with thiols and nucleophilic oxygen sources has been reported.
Mechanochemistry for “no solvent, no base” preparation of hydantoin-based active pharmaceutical ingredients: nitrofurantoin and dantrolene
The gram-scale mechanochemical preparation of marketed drugs Nitrofurantoin and Dantrolene is herein reported.
Rethinking Co(CO3)0.5(OH)·0.11H2O: a new property for highly selective electrochemical reduction of carbon dioxide to methanol in aqueous solution
Co(CO3)0.5(OH)·0.11H2O: a new property for highly selective electroreduction of CO2 to CH3OH.
Real-time reaction control for solar production of chemicals under fluctuating irradiance
A simple and inexpensive reaction control system mitigates the impact of solar irradiance fluctuations on the conversion of a sunlight-powered photochemical reaction, affording constant product quality.
Mechanochemistry – a new powerful green approach to the direct synthesis of alkoxysilanes
The present work shows a new one-stage mechanochemical method for the direct synthesis of alkoxysilanes.
A more sustainable and efficient access to IMes·HCl and IPr·HCl by ball-milling
A user and environmentally friendly synthesis of the widely used N-heterocyclic carbene (NHC) precursors was realized using mechanochemistry.
Decarboxylation of α,β-unsaturated aromatic lactones: synthesis of E-ortho-hydroxystilbenes from 3-arylcoumarins or isoaurones
A simple and eco-friendly strategy for the synthesis of E-ortho-hydroxystilbenes from two kinds of α,β-unsaturated aromatic lactones is described.
Recyclable Cu/C3N4 composite catalysed homo- and cross-coupling of terminal alkynes under mild conditions
A facile, practical and recyclable Cu–N–C composite catalyst with good catalytic activity for both homo- & cross-coupling of terminal alkynes.
Ni-Catalyzed chemoselective alcoholysis of N-acyloxazolidinones
We report the first Ni(cod)2/bipyr.-catalyzed alcoholysis of N-acyloxazolidinones to deliver esters.
Rhodium-catalyzed intermolecular C(sp3)–H amination in a purely aqueous system
An efficient Rh-catalyzed intermolecular C(sp3)–H amination in a purely aqueous system is developed for the first time.
Utilization of fluoroform for difluoromethylation in continuous flow: a concise synthesis of α-difluoromethyl-amino acids
Difluoromethylated esters, malonates and amino acids (including the drug eflornithine) are obtained by a gas–liquid continuous flow protocol employing the abundant waste product fluoroform as an atom-efficient reagent.
Is oxidation–reduction a real robust strategy for lignin conversion? A comparative study on lignin and model compounds
The enigma of the oxidation–reduction strategy for lignin valorization was disclosed over heterogenous catalysts and was compared with model compound studies.
Selective formylation or methylation of amines using carbon dioxide catalysed by a rhodium perimidine-based NHC complex
Selective formylation and methylation of amines using low pressure CO2 as a carbon source; mechanistic studies, time course and reaction scope.
The identification and use of robust transaminases from a domestic drain metagenome
Transaminases remain one of the most promising biocatalysts for use in chiral amine synthesis. Here, the identification, cloning and screening of novel transaminases from a drain metagenome is described, with some enzymes exhibiting outstanding properties such as 50% DMSO solvent tolerance.
A versatile biobased continuous flow strategy for the production of 3-butene-1,2-diol and vinyl ethylene carbonate from erythritol
A versatile, tunable and robust continuous flow procedure for the upgrading of erythritol toward important industrial building blocks.
A bio-based route to the carbon-5 chemical glutaric acid and to bionylon-6,5 using metabolically engineered Corynebacterium glutamicum
Here, we present a green route to glutaric acid, a chemical of recognized industrial value, using a tailor-made cell factory.
Ionic liquid ion exchange: exclusion from strong interactions condemns cations to the most weakly interacting anions and dictates reaction equilibrium
Ion exchange is determined by the interaction energy and impacts process performance by change of physicochemical properties and reactivity.
Scalable thin-layer membrane reactor for heterogeneous and homogeneous catalytic gas–liquid reactions
Scalable, sustainable, and safe thin-layer membrane reactor can potentially accelerate the adoption of heterogeneous and homogenous catalytic gas–liquid reactions in the pharmaceutical and fine chemical industries.
Supported gold- and silver-based catalysts for the selective aerobic oxidation of 5-(hydroxymethyl)furfural to 2,5-furandicarboxylic acid and 5-hydroxymethyl-2-furancarboxylic acid
The oxidation of HMF is performed using highly active heterogeneous gold- and, for the first time, silver-based catalysts.
Repurposing bacterial extracellular matrix for selective and differential abstraction of rare earth elements
Highly robust engineered protein matrices derived from bacteria were used to isolate rare earth elements from mixtures of metals. The filters were re-used over multiple cycles and the bound REE were readily recovered.
Programming cascade reactions interfacing biocatalysis with transition-metal catalysis in Deep Eutectic Solvents as biorenewable reaction media
Transition-metal complexes and purified ketoreductases work together in eutectic mixtures for the synthesis of enantiopure secondary alcohols.
Trihalide ionic liquids as non-volatile oxidizing solvents for metals
Various trihalide ionic liquids were prepared and used as non-volatile solvent to oxidatively dissolve metals.
Life-cycle assessment and techno-economic analysis of the utilization of bio-oil components for the production of three chemicals
Bio-based chemicals have gained more widespread attention than bio-fuels because of the decline in crude oil prices.
Carbene-catalyzed aerobic oxidation of isoquinolinium salts: efficient synthesis of isoquinolinones
A mild and environmentally friendly carbene-catalyzed aerobic oxidation of isoquinolinium salts was successfully realized.
Enhanced H2 evolution from photocatalytic cellulose conversion based on graphitic carbon layers on TiO2/NiOx
An enhanced photoreforming of biomass was achieved by loading a graphitic carbon layer on TiO2/NiOx nanoparticles.
Robust open cellular porous polymer monoliths made from cured colloidal gels of latex particles
Preparation of polymer monoliths from the coagulation of particles, synthesized by soap-free emulsion polymerisation, using water as the only solvent.
Catalytic cascade conversion of furfural to 1,4-pentanediol in a single reactor
The selective transformation of furfural to 1,4-pentanediol has been achieved with up to 90% yield in a CO2/H2/H2O system over Ru catalytic species supported on a mesoporous carbon.
An eco-compatible pathway to new hydrotropes from tetraols
An eco-compatible two-step synthesis for the production of new hydrotropes with attractive salt tolerance and solubilizing properties.
Three-dimensional porous graphene-like sheets synthesized from biocarbon via low-temperature graphitization for a supercapacitor
Synthetic procedure of three-dimensional porous graphene-like sheets via low-temperature graphitization.
Electrochemical production of syngas from CO2 captured in switchable polarity solvents
Switchable polarity solvents allowed for the first time the electrochemical reduction of captured CO2 for an efficient production of syngas.
Lewis pairs for ring-opening alternating copolymerization of cyclic anhydrides and epoxides
Simple and low-toxic Lewis pairs were introduced for ring-opening alternating copolymerization of anhydrides and epoxides to prepare diversified polyesters.
Excitation of H2O at the plasma/water interface by UV irradiation for the elevation of ammonia production
An interfacial reaction between the UV irradiated water phase (H˙ provides) and the electron-discharged nitrogen-gas phase (N atom provides) produces ammonia efficiently.
A strategy of ketalization for the catalytic selective dehydration of biomass-based polyols over H-beta zeolite
A strategy is presented to control the etherification site in sugar alcohols via ketalization of the terminal vicinal-diol group with a ketone.
Low energy recycling of ionic liquids via freeze crystallization during cellulose spinning
An energy saving method of freeze crystallization for recycling ionic liquids was investigated in a cellulose spinning process.
Metal-free tandem cyclization/hydrosilylation to construct tetrahydroquinoxalines
B(C6F5)3-Catalyzed tandem cyclization/hydrosilylation for the step-economical construction of 1,2,3,4-tetrahydroquinoxalines from readily available starting materials has been developed.
Waste-minimised copper-catalysed azide–alkyne cycloaddition in Polarclean as a reusable and safe reaction medium
Herein we report the first example of a generally useful organic reaction, namely the copper-catalysed azide–alkyne cycloaddition, performed in a Polarclean/water mixture as a reaction medium.
Mechanistic studies of base-catalysed lignin depolymerisation in dimethyl carbonate
Various analytical techniques and DFT calculations have been applied in studying base-catalysed lignin degradation in dimethyl carbonate.
Heterogeneous hydroformylation of long-chain alkenes in IL-in-oil Pickering emulsion
An IL-in-oil Pickering emulsion prepared with Rh-sulfo-xantphos as the catalyst and dendritic mesoporous silica nanospheres as the stabilizer could efficiently catalyze the hydroformylation of 1-dodecene to afford TOF as high as 413 h−1.
High performance man-made cellulosic fibres from recycled newsprint
High performance man-made cellulosic fibres from recycled newsprint.
Towards sustainable manufacture of epichlorohydrin from glycerol using hydrotalcite-derived basic oxides
Regenerable hydrotalcite-derived Mg–Al oxide is an effective heterogeneous base to avoid waste formation and enable halogen recycling in the glycerol-to-epichlorohydrin process.
About this collection
Welcome to our online rolling collection of the hottest work published in Green Chemistry. Here we feature all the 2018 Green Chemistry articles highlighted as HOT by the handling editor or our referees. Congratulations to all the authors whose articles are featured.