Introduction to electrochemistry for health applications
Craig E. Banks, Tony Killard and B. Jill Venton introduce the Analytical Methods themed issue on electrochemistry for health applications.
Low fouling strategies for electrochemical biosensors targeting disease biomarkers
This minireview summarizes recent trends in the development of low fouling electrochemical biosensors based on different antifouling materials.
Frontiers in electrochemical sensors for neurotransmitter detection: towards measuring neurotransmitters as chemical diagnostics for brain disorders
This critical review highlights significant technical advances and in vivo studies from the last five years that facilitate the development of diagnostic tools for brain disorders.
Alkaline phosphatase-based electrochemical sensors for health applications
Alkaline phosphatase-based electrochemical biosensors for the diagnosis and monitoring of diseases have been reviewed.
Electrochemical biosensors for autoantibodies in autoimmune and cancer diseases
Autoantibodies (AAbs) are antibodies produced against our own cells or tissues either providing a first defense against infections or indicating the presence of pathological processes.
Review: new insights into optimizing chemical and 3D surface structures of carbon electrodes for neurotransmitter detection
The carbon-fiber microelectrode has been used for decades as a neurotransmitter sensor, but many new carbon electrodes have recently been developed with beneficial electrochemical properties that take advantage of surface chemistry and surface structure.
Potentiometric detection of biogenic amines utilizing affinity on a 4-mercaptobenzoic acid monolayer
Biogenic amines in water were detected potentiometrically utilizing an easy-to-prepare sensing electrode functionalized with a self-assembled monolayer (SAM) of 4-mercaptobenzoic acid (BA).
Laccase from Botryosphaeria rhodina MAMB-05 as a biological component in electrochemical biosensing devices
A crude laccase preparation from Botryosphaeria rhodina MAMB-05 was employed to construct an electrochemical biosensor using nanostructured carbon black to epinephrine determination.
A first adrenalone electrochemical sensor using a gold-nanoparticle/poly(pyrrole) composite-modified graphite electrode
In this study, a pencil graphite electrode (PGE) modified with a composite of polypyrrole and Au nanoparticles (Au-NPs/PP/PGE) was developed and evaluated as a novel electrochemical sensor for the determination of adrenalone for the first time.
Design and fabrication of surface capped palladium nanoclusters for the subnanomolar sensing of glutathione
In this work, a palladium atomic cluster modified glassy carbon electrode (PdAC/GCE) was developed by potentiodynamic electrodeposition in the presence of an anionic surfactant for the electrochemical detection of glutathione (GSH).
Polymer modified carbon fiber-microelectrodes and waveform modifications enhance neurotransmitter metabolite detection
Carbon-fiber microelectrodes (CFMEs) have been used for several years for the detection of neurotransmitters such as dopamine.
Sensitive and portable electrochemical immunoassay for lipoprotein-associated phospholipase A2 using BSA-doped CaCO3 nanospheres to regulate pH readout
A simple and sensitive electrochemical immunoassay method was developed for the quantitative monitoring of lipoprotein-associated phospholipase A2 (Lp-PLA2) on a low-cost microtiter plate by using a portable handheld pH meter.
Robust epidermal tattoo electrode platform for skin physiology monitoring
Robustness in an impedance-based tattoo electrode platform is achieved through the integration of novel material approaches for skin physiology monitoring.
A sensitive and regenerative electrochemical immunosensor for quantitative detection of Escherichia coli O157:H7 based on stable polyaniline coated screen-printed carbon electrode and rGO-NR-Au@Pt
An electrochemical immunosensor was constructed for the detection of E. coli O157:H7 using Au@Pt, rGO and regenerative leucoemeraldine PANI/AuNPs.
A facile voltammetric method for detection of heparin in plasma based on the polyethylenimine modified electrode
A simple but effective polyethylenimine-based voltammetric method for rapid detection of heparin in plasma.
Increasing the electrochemical system performance using a magnetic nanostructured sensor for simultaneous determination of L-tyrosine and epinephrine
Designing a sensitive magnetic nanostructured sensor for simultaneous determination of L-tyrosine and epinephrine.
Non-invasive monitoring of a circadian relevant biomarker from easily accessible body fluids using hybrid aqueous–ionic buffer interfaces on flexible substrates
In this paper, we demonstrate a hybrid flexible biosensor comprised of an aqueous and ionic interface integrated onto metallic gold microelectrodes for rapid and noninvasive monitoring of cortisol.
Analytical determination of heroin, fentanyl and fentalogues using high-performance liquid chromatography with diode array and amperometric detection
We report a combination of HPLC and electrochemistry towards the detection of heroin, fentanyl and ten fentalogues.
On the origin of electrochemical surface-enhanced Raman spectroscopy (EC-SERS) signals for bacterial samples: the importance of filtered control studies in the development of new bacterial screening platforms
The importance of filtered control studies for ascertaining the origin of bacterial SERS signals is highlighted.
Label free electrochemical detection of cardiac biomarker troponin T using ZnSnO3 perovskite nanomaterials
Perovskite nanomaterial based electrochemical biosensor for label free sub femtomolar detection of cardiac biomarker troponin T.
Simultaneous detection of hydroquinone and catechol with decreasing pH at a bare glassy carbon electrode surface
Hydroquinone (HQ) and catechol (CC) are two isomers, which often coexist and interfere with each other during their identification in samples.
Mesoporous Pd@Pt core–shell nanoparticles supported on multi-walled carbon nanotubes as a sensing platform: application in simultaneous electrochemical detection of anticancer drugs doxorubicin and dasatinib
A novel electrochemical sensor based on Pd@Pt/MWCNT composite for simultaneous detection of doxorubicin and dasatinib.
Disposable screen-printed electrodes modified with uniform iron oxide nanocubes for the simple electrochemical determination of meclizine, an antihistamine drug
A disposable screen-printed carbon electrode modified with uniform iron oxide nanocubes was explored for simple electrochemical determination of meclizine, an antihistamine drug.
Electrochemical determination of PIK3CA gene associated with breast cancer based on molybdenum disulfide nanosheet-supported poly(indole-6-carboxylic acid)
A sensitive electrochemical strategy for determination of PIK3CA gene associated with breast cancer was developed based on MoS2 nanosheet-supported PIn6COOH.
Optimization of a microchip electrophoresis method with electrochemical detection for the determination of nitrite in macrophage cells as an indicator of nitric oxide production
A transient isotachophoresis separation and Pt black working electrode allow detection of nitrite in stimulated macrophage cells with improved sensitivity.
Voltammetric analysis of naringenin at a disposable pencil graphite electrode – application to polyphenol content determination in citrus juice
The electrochemical behaviour of the flavonoid naringenin (NGN) was investigated for the first time by cyclic voltammetry (CV), using a disposable electroactivated pencil graphite electrode (PGE*).
Gold nanoparticle decorated multiwalled carbon nanotube modified electrodes for the electrochemical determination of theophylline
Theophylline determination at gold nanoparticle/carbon nanotube modified electrode and analysis in commercial pharmaceutical and tea samples.
An alpha-fetoprotein electrochemical immunosensor based on a carbon/gold bi-nanoparticle platform
We report an electrochemical immunosensor for alpha-fetoprotein (AFP) on an immobilisation layer of carbon and gold bi-nanoparticles. XRD and immunosensor responses to 10 ng mL−1 alpha-fetoprotein: (a) GCE/antibody/BSA, (b) GCE/AuNPs/antibody/BSA, (c) GCE/CNPs/antibody/BSA, (d) GCE/CNPs/AuNPs/antibody/BSA.
A new electrochemiluminescence biosensor for the detection of glucose based on polypyrrole/polyluminol/Ni(OH)2–C3N4/glucose oxidase-modified graphite electrode
A new electrochemiluminescence (ECL) glucose biosensor based on polypyrrole/polyluminol/C3N4–Ni(OH)2/glucose oxidase (Ppy/Plu/C3N4–Ni(OH)2/GOx) was fabricated by the electropolymerization of pyrrole and luminol in acidic medium for glucose detection.
A potentiometric aptasensor for carcinoembryonic antigen (CEA) on graphene oxide nanosheets using catalytic recycling of DNase I with signal amplification
A label-free potentiometric aptasensing platform was designed for detection of carcinoembryonic antigen on a graphene oxide-modified electrode coupling with target recycling-assisted signal amplification.
Simultaneous determination of amlodipine and losartan using an iron metal–organic framework/mesoporous carbon nanocomposite-modified glassy carbon electrode by differential pulse voltammetry
An FeMOF/MC composite as an excellent electrocatalyst towards the simultaneous electrochemical determination of AML and LOS.
Graphene oxide/lysine composite – a potent electron mediator for detection of diazepam
A graphene oxide/lysine (GO/lys) composite, synthesized using a very simple chemical method, has been used to modify a glassy carbon electrode for the voltammetric detection of diazepam.
An electrochemical immunosensor based on a multiple signal amplification strategy for highly sensitive detection of prostate specific antigen
A sandwich-type electrochemical immunosensor was developed based on a multiple signal amplification strategy.
Facile and feasible conductometric immunoanalytical assay for alpha-fetoprotein using platinum-functionalized graphitic carbon nitride nanosheets
A conductometric immunoanalytical method was developed for the sensitive detection of the liver cancer biomarker (alpha-fetoprotein, AFP), using platinum (Pt)-functionalized graphitic carbon nitride (g-C3N4) nanosheets..
About this collection
A collection of papers and reviews focussing on electrochemistry for health applications. The scope of this themed collection is intentionally broad to cover electrochemical sensing, biosensing and applications in diagnostics and monitoring and neuroelectrochemistry. This online collection is guest edited by Associate Editors C. Banks and B. Jill Venton and Reviews Editor Tony Killard.