Themed collection Analyst HOT Articles 2024

97 items - Showing page 1 of 2
Open Access Minireview

Analytical applications of droplet deposition Raman spectroscopy

This review summarizes sensitive analytical detection. Analyte pre-concentration by droplet deposition is combined with SERS enhancement.

Graphical abstract: Analytical applications of droplet deposition Raman spectroscopy
From the themed collection: Analyst HOT Articles 2024
Minireview

Impact electrochemistry for biosensing: advances and future directions

This minireview summarizes the recent advancements in impact electrochemistry-based biosensing over the past two to three years and provides insights into the future directions of this field.

Graphical abstract: Impact electrochemistry for biosensing: advances and future directions
From the themed collection: Analyst HOT Articles 2024
Minireview

DNA nanotechnology-based nucleic acid delivery systems for bioimaging and disease treatment

This review aims to introduce the development of DNA nanotechnology and recent advances of DNA nanostructure-based delivery systems for bioimaging, disease diagnosis, and therapeutic applications.

Graphical abstract: DNA nanotechnology-based nucleic acid delivery systems for bioimaging and disease treatment
From the themed collection: Analyst HOT Articles 2024
Minireview

Noble metal-free SERS: mechanisms and applications

Surface-enhanced Raman scattering (SERS) is a very important tool in vibrational spectroscopy.

Graphical abstract: Noble metal-free SERS: mechanisms and applications
From the themed collection: Analyst HOT Articles 2024
Tutorial Review

Recent progress of metal–organic framework-based nanozymes with oxidoreductase-like activity

The research progress of MOF-based nanozymes with oxidoreductase-like activity.

Graphical abstract: Recent progress of metal–organic framework-based nanozymes with oxidoreductase-like activity
From the themed collection: Analyst HOT Articles 2024
Tutorial Review

A review on recent advances in assays for DNMT1: a promising diagnostic biomarker for multiple human cancers

The abnormal expression of human DNA methyltransferases (DNMTs) is closely related with the occurrence and development of a wide range of human cancers.

Graphical abstract: A review on recent advances in assays for DNMT1: a promising diagnostic biomarker for multiple human cancers
From the themed collection: Analyst HOT Articles 2024
Tutorial Review

Shedding light on cellular dynamics: the progress in developing photoactivated fluorophores

Photoactivated fluorophores (PAFs) are highly effective imaging tools that exhibit a removal of caging groups upon light excitation, resulting in the restoration of their bright fluorescence.

Graphical abstract: Shedding light on cellular dynamics: the progress in developing photoactivated fluorophores
From the themed collection: Analyst HOT Articles 2024
Critical Review

Advances in uremic toxin detection and monitoring in the management of chronic kidney disease progression to end-stage renal disease

Patients with end-stage kidney disease (ESKD) rely on dialysis to remove toxins and stay alive.

Graphical abstract: Advances in uremic toxin detection and monitoring in the management of chronic kidney disease progression to end-stage renal disease
From the themed collection: Analyst HOT Articles 2024
Critical Review

Deciphering biomolecular complexities: the indispensable role of surface-enhanced Raman spectroscopy in modern bioanalytical research

Overview of recent studies on SERS for biomolecular complexities analysis.

Graphical abstract: Deciphering biomolecular complexities: the indispensable role of surface-enhanced Raman spectroscopy in modern bioanalytical research
From the themed collection: Analyst HOT Articles 2024
Open Access Critical Review

Separation and purification of fluorescent carbon dots – an unmet challenge

Different purification techniques for carbon dots.

Graphical abstract: Separation and purification of fluorescent carbon dots – an unmet challenge
From the themed collection: Analyst HOT Articles 2024
Critical Review

Recent advances of nanopore technique in single cell analysis

Overview of nanopores for single cell detection.

Graphical abstract: Recent advances of nanopore technique in single cell analysis
From the themed collection: Analyst HOT Articles 2024
Critical Review

Recent advances in biological molecule detection based on a three-dimensional graphene structure

This review summarizes the recent advances in three-dimensional graphene structures, including preparation methods and their detection application in the biomedical field.

Graphical abstract: Recent advances in biological molecule detection based on a three-dimensional graphene structure
From the themed collection: Analyst HOT Articles 2024
Critical Review

Carbon dots@noble metal nanoparticle composites: research progress report

Synthesis, characterization, and application of carbon dots@noble metal nanocomposites.

Graphical abstract: Carbon dots@noble metal nanoparticle composites: research progress report
From the themed collection: Analyst HOT Articles 2024
Critical Review

Recent advances in optical biosensing and imaging of telomerase activity and relevant signal amplification strategies

Fluorometric, colorimetry, chemiluminescence, SERS, and dual-mode techniques for biosensing and imaging of telomerase are summerized. Relevant signal amplification strategies are included to provide ideas for exploration of more practicable methods.

Graphical abstract: Recent advances in optical biosensing and imaging of telomerase activity and relevant signal amplification strategies
From the themed collection: Analyst HOT Articles 2024
Critical Review

A review of electrochemical impedance as a tool for examining cell biology and subcellular mechanisms: merits, limits, and future prospects

Herein the development of cellular impedance biosensors, electrochemical impedance spectroscopy, and the general principles and terms associated with the cell–electrode interface is reviewed.

Graphical abstract: A review of electrochemical impedance as a tool for examining cell biology and subcellular mechanisms: merits, limits, and future prospects
From the themed collection: Analyst HOT Articles 2024
Critical Review

Optical sensors (optodes) for multiparameter chemical imaging: classification, challenges, and prospects

Seeing is believing - and optical sensors (optodes) are ideal tools to make chemistry visible in real time. Find out how technological and chemical advances enable multiparameter imaging of complex samples.

Graphical abstract: Optical sensors (optodes) for multiparameter chemical imaging: classification, challenges, and prospects
From the themed collection: Analyst HOT Articles 2024
Communication

Preparation and utilization of carbon dots as a nanoprobe for sensitive detection of tartrazine and palladium (II)

A novel green and eco-friendly carbon-based nanoprobe was developed for dual-channel analysis of tartrazine (Trz) and Pd(II) involving, respectively, fluorescence resonance energy transfer (FRET) and electron transfer mechanisms.

Graphical abstract: Preparation and utilization of carbon dots as a nanoprobe for sensitive detection of tartrazine and palladium (ii)
From the themed collection: Analyst HOT Articles 2024
Accepted Manuscript - Communication

Visual Electrochemiluminescence from an All-Solid-State Electrochemical Cell

From the themed collection: Analyst HOT Articles 2024
Communication

Preparation of near-infrared photoacoustic imaging and photothermal treatment agent for cancer using a modifiable acid-triggered molecular platform

We report here a tunable proton platform for the tumor micro-acid environment that is used for tumor imaging and treatment.

Graphical abstract: Preparation of near-infrared photoacoustic imaging and photothermal treatment agent for cancer using a modifiable acid-triggered molecular platform
From the themed collection: Analyst HOT Articles 2024
Communication

Ultra-clean pure shift NMR with optimal water suppression for analysis of aqueous pharmaceutical samples

Pure shift NMR experiments greatly enhance spectral resolution by collapsing multiplet structures into singlets and, with optimal water suppression, can be used for aqueous samples.

Graphical abstract: Ultra-clean pure shift NMR with optimal water suppression for analysis of aqueous pharmaceutical samples
From the themed collection: Analyst HOT Articles 2024
Communication

Characterization of nanozyme kinetics for highly sensitive detection

Enzymes (1) and nanozymes (2) have significant differences in the Michaelis–Menten constant. Detection of nanozymes using enzyme substrates results in lower catalytic activity and a significantly higher limit of detection.

Graphical abstract: Characterization of nanozyme kinetics for highly sensitive detection
From the themed collection: Analyst HOT Articles 2024
Communication

Exploration of glutaredoxin-1 oxidative modification in carbon nanomaterial-induced hepatotoxicity

Graphene oxide can increase the levels of intracellular H2O2 and ˙OH, and cause the irreversible oxidative modification. This leads to the activation of the JNK/p38 signaling pathway and promote hepatocyte apoptosis.

Graphical abstract: Exploration of glutaredoxin-1 oxidative modification in carbon nanomaterial-induced hepatotoxicity
From the themed collection: Analyst HOT Articles 2024
Communication

Split G-quadruplex based PfAgo sensing platform for nucleotide mutation discrimination and human genotyping

A split G-quadruplex based PfAgo sensing platform was developed for nucleotide mutation discrimination and human genotyping.

Graphical abstract: Split G-quadruplex based PfAgo sensing platform for nucleotide mutation discrimination and human genotyping
From the themed collection: Analyst HOT Articles 2024
Open Access Communication

An innovative in situ AFM system for a soft X-ray spectromicroscopy synchrotron beamline

The development of an in situ combination of AFM and soft X-ray μXRF in a single instrument, with AFM integration accomplished without substantial original set-up alteration.

Graphical abstract: An innovative in situ AFM system for a soft X-ray spectromicroscopy synchrotron beamline
From the themed collection: Analyst HOT Articles 2024
Communication

Ultrasensitive electrochemical detection and inhibition evaluation of DNA methyltransferase based on cascade strand displacement amplification

An electrochemical sensing approach for ultrasensitive MTase activity assay is proposed based on cascade strand displacement polymerization after specific cleavage reaction in the methylated state.

Graphical abstract: Ultrasensitive electrochemical detection and inhibition evaluation of DNA methyltransferase based on cascade strand displacement amplification
From the themed collection: Analyst HOT Articles 2024
Paper

Fabrication of an all-in-one self-enhanced solid-state electrochemiluminescence sensing platform for the selective detection of spermine

Fabrication of chemically synthesised silica polyethylene nanoparticles acted as an all-in-one solid-state ECL platform for selective sensing of spermine which offers an expediting the miniaturization of sensing devices and point-of-care needs.

Graphical abstract: Fabrication of an all-in-one self-enhanced solid-state electrochemiluminescence sensing platform for the selective detection of spermine
From the themed collection: Analyst HOT Articles 2024
Paper

A bimodal time-gated luminescence–magnetic resonance imaging nanoprobe based on a europium(III) complex anchored on BSA-coated MnO2 nanosheets for highly selective detection of H2O2

A novel nanocomposite, [Eu(BTD)3(DPBT)]–BSA@MnO2, is reported to serve as an effective nanoprobe for bimodal time-gated luminescence (TGL) and magnetic resonance (MR) imaging of H2O2 in vitro and in vivo.

Graphical abstract: A bimodal time-gated luminescence–magnetic resonance imaging nanoprobe based on a europium(iii) complex anchored on BSA-coated MnO2 nanosheets for highly selective detection of H2O2
From the themed collection: Analyst HOT Articles 2024
Open Access Paper

Acoustic detection of a mutation-specific Ligase Chain Reaction based on liposome amplification

Development of an acoustic methodology for the sensitive detection of LCR-amplified cancer mutations at a single point mutation-level.

Graphical abstract: Acoustic detection of a mutation-specific Ligase Chain Reaction based on liposome amplification
From the themed collection: Analyst HOT Articles 2024
Paper

A binding-triggered hybridization chain reaction cascade multi-site activated CRISPR/Cas12a signal amplification strategy for sensitive detection of α-synuclein

A binding-triggered hybridization chain reaction cascade multi-site activated CRISPR/Cas12a signal amplification strategy for sensitive detection of α-synuclein. This work provides a promising analysis tool for the early diagnosis of Parkinson's disease.

Graphical abstract: A binding-triggered hybridization chain reaction cascade multi-site activated CRISPR/Cas12a signal amplification strategy for sensitive detection of α-synuclein
From the themed collection: Analyst HOT Articles 2024
Paper

Electroactive polymer tag modified nanosensors for enhanced intracellular ATP detection

We developed a simple and effective electrochemical signal amplification strategy for intracellular ATP quantification, which replaces the regular ATP aptamer-linked ferrocene monomer to a polymer on electrochemical nanosensors.

Graphical abstract: Electroactive polymer tag modified nanosensors for enhanced intracellular ATP detection
From the themed collection: Analyst HOT Articles 2024
Paper

Shadow electrochemiluminescence imaging of giant liposomes opening at polarized electrodes

In this work, the release of giant liposome (∼100 μm in diameter) content was imaged by shadow electrochemiluminescence (ECL) microscopy.

Graphical abstract: Shadow electrochemiluminescence imaging of giant liposomes opening at polarized electrodes
From the themed collection: Analyst HOT Articles 2024
Paper

Maintenance-free antifouling polymeric membrane potentiometric sensors based on self-polishing coatings

For the first time, a novel strategy for fabrication of maintenance-free and contamination-free polymeric membrane potentiometric sensors is proposed.

Graphical abstract: Maintenance-free antifouling polymeric membrane potentiometric sensors based on self-polishing coatings
From the themed collection: Analyst HOT Articles 2024
Paper

Optical tracking of the heterogeneous solvent diffusion dynamics and swelling kinetics of single polymer microspheres

The upper is a schematic of the swelling kinetics of a single representative PMMA microsphere in solvent at different reaction time nodes. The bottom shows the corresponding optical tracking of the extraction process of edge changes during the swelling of a single PMMA particle.

Graphical abstract: Optical tracking of the heterogeneous solvent diffusion dynamics and swelling kinetics of single polymer microspheres
From the themed collection: Analyst HOT Articles 2024
Open Access Paper

In situ monitoring of the shikimate pathway: a combinatorial approach of Raman reverse stable isotope probing and hyperspectral imaging

Sensing and visualization of metabolites and metabolic pathways in situ are significant requirements for tracking their spatiotemporal dynamics in a non-destructive manner.

Graphical abstract: In situ monitoring of the shikimate pathway: a combinatorial approach of Raman reverse stable isotope probing and hyperspectral imaging
From the themed collection: Analyst HOT Articles 2024
Paper

A multi-channel electrochemical biosensor based on polyadenine tetrahedra for the detection of multiple drug resistance genes

PolyA-TDF enables PCR-free qualitative detection of drug-resistant genes, integrating biosensor recognition and probe immobilization via strong adsorption to gold.

Graphical abstract: A multi-channel electrochemical biosensor based on polyadenine tetrahedra for the detection of multiple drug resistance genes
From the themed collection: Analyst HOT Articles 2024
Open Access Paper

A facile method for monitoring sphingomyelin synthase activity in HeLa cells using liquid chromatography/mass spectrometry

An LC-MS/MS-based assay for monitoring sphingomyelin synthase (SMS) activity was developed. The method is highly useful in screening novel inhibitors for SMS.

Graphical abstract: A facile method for monitoring sphingomyelin synthase activity in HeLa cells using liquid chromatography/mass spectrometry
From the themed collection: Analyst HOT Articles 2024
Paper

A mesothelin microsensor based on an embedded thionine electronic medium within an imprinted polymer on an acupuncture needle electrode

An electrochemical microsensor of mesothelin was prepared based on surface imprinted nano-interface coordinated embedded thionine, and it was constructed via a green route of electrosynthesis and self-assembly.

Graphical abstract: A mesothelin microsensor based on an embedded thionine electronic medium within an imprinted polymer on an acupuncture needle electrode
From the themed collection: Analyst HOT Articles 2024
Open Access Accepted Manuscript - Paper

Understanding Dynamic Voltammetry in a Dissolving Microdroplet

From the themed collection: Analyst HOT Articles 2024
Open Access Paper

Spatially resolved quantification of oxygen consumption rate in ex vivo lymph node slices

A spatially resolved optical method was developed to measure oxygen consumption rate (OCR) in ex vivo tissue slices. This method revealed regional OCR variations and is a valuable tool for exploring tissue hypoxia dynamics and immune cell activity.

Graphical abstract: Spatially resolved quantification of oxygen consumption rate in ex vivo lymph node slices
From the themed collection: Analyst HOT Articles 2024
Paper

Paper spray mass spectrometry combined with machine learning as a rapid diagnostic for chronic kidney disease

Direct analysis of patient urine by paper spray mass spectrometry combined with machine learning has the potential to be used as a rapid and simple diagnostic tool for chronic kidney disease.

Graphical abstract: Paper spray mass spectrometry combined with machine learning as a rapid diagnostic for chronic kidney disease
From the themed collection: Analyst HOT Articles 2024
Paper

HFM-Tracker: a cell tracking algorithm based on hybrid feature matching

A novel cell tracking algorithm, named HFM-Tracker (Hybrid Feature Matching Tracker), is proposed to accurately track the migratory behavior of cells through the capture of time-lapse cell images.

Graphical abstract: HFM-Tracker: a cell tracking algorithm based on hybrid feature matching
From the themed collection: Analyst HOT Articles 2024
Paper

A self-powered electrochemical aptasensor for the detection of 17β-estradiol based on carbon nanocages/gold nanoparticles and DNA bioconjugate mediated biofuel cells

A BFC-based electrochemical aptasensor for E2 detection based on CNCs/AuNPs and PMNPs@aptamer DNA bioconjugate.

Graphical abstract: A self-powered electrochemical aptasensor for the detection of 17β-estradiol based on carbon nanocages/gold nanoparticles and DNA bioconjugate mediated biofuel cells
From the themed collection: Analyst HOT Articles 2024
Paper

An electrochemical biosensor for Staphylococcus aureus detection based on a multilevel surface 3D micro/nanostructure

An electrochemical biosensor for fast and sensitive Staphylococcus aureus detection is achieved by using surface multilevel 3D micro/nanostructures.

Graphical abstract: An electrochemical biosensor for Staphylococcus aureus detection based on a multilevel surface 3D micro/nanostructure
From the themed collection: Analyst HOT Articles 2024
Paper

Novel methods for the rapid and sensitive detection of Nipah virus based on a CRISPR/Cas12a system

A schematic diagram of RAA-CRISPR/Cas12a-FQ and RAA-CRISPR/Cas12a-FB methods in NiV detection.

Graphical abstract: Novel methods for the rapid and sensitive detection of Nipah virus based on a CRISPR/Cas12a system
From the themed collection: Analyst HOT Articles 2024
Open Access Paper

Generation and reactivity of the fragment ion [B12I8S(CN)] in the gas phase and on surfaces

CID fragmentation of the synthesized [B12I11(SCN)]2− ions yields [B12I8S(CN)] ions. The reactivity of these ions was studied in the gas phase and in ion soft-landing experiments, where selectivity toward certain functional groups was discovered.

Graphical abstract: Generation and reactivity of the fragment ion [B12I8S(CN)]− in the gas phase and on surfaces
From the themed collection: Analyst HOT Articles 2024
Open Access Paper

Transient theory for scanning electrochemical microscopy of biological membrane transport: uncovering membrane–permeant interactions

The finte element simulation predicts that interactions of a biological membrane with a permeant can be determined quantitatively by employing transient scanning electrochemical microscopy to discriminate between one-step and two-step transport.

Graphical abstract: Transient theory for scanning electrochemical microscopy of biological membrane transport: uncovering membrane–permeant interactions
From the themed collection: Analyst HOT Articles 2024
Open Access Paper

Resistive pulse analysis of chiral amino acids utilizing metal–amino acid crystallization differences

Here, we report a proof-of-concept resistive pulse method for analyzing chiral amino acids utilizing metal–amino acid crystallization differences.

Graphical abstract: Resistive pulse analysis of chiral amino acids utilizing metal–amino acid crystallization differences
From the themed collection: Analyst HOT Articles 2024
Paper

Anisotropic growth of gold anchors on CdSe semiconductor quantum platelets for self-assembled architectures with well-connected electronic circuits for the electrochemical detection of enrofloxacin

Anisotropic growth of gold anchors on CdSe semiconductor quantum platelets for self-assembled architectures with well-connected electronic circuits for enrofloxacin electro-oxidation.

Graphical abstract: Anisotropic growth of gold anchors on CdSe semiconductor quantum platelets for self-assembled architectures with well-connected electronic circuits for the electrochemical detection of enrofloxacin
From the themed collection: Analyst HOT Articles 2024
Paper

Photonic–plasmonic resonator for SERS biodetection

We construct a hybrid photonic–plasmonic resonator SERS substrate with high enhancement factor and can be used to detect cancer biomarkers in serum for differentiation of different cancers.

Graphical abstract: Photonic–plasmonic resonator for SERS biodetection
From the themed collection: Analyst HOT Articles 2024
Paper

Smartphone-based paper strip assay for putrescine and spermidine detection using hybrid organic–inorganic perovskite with Eu3+ complex

A new method utilizing fluorescent ratiometry is proposed for detecting putrescine and spermidine.

Graphical abstract: Smartphone-based paper strip assay for putrescine and spermidine detection using hybrid organic–inorganic perovskite with Eu3+ complex
From the themed collection: Analyst HOT Articles 2024
Paper

Overcoming aggregation with laser heated nanoelectrospray mass spectrometry: thermal stability and pathways for loss of bicarbonate from carbonic anhydrase II

Laser-heated electrospray ionization with mass spectrometry enables melting temperature measurements of aggregation-prone proteins from which thermochemical and mechanistic information about protein unfolding and ligand loss is deduced.

Graphical abstract: Overcoming aggregation with laser heated nanoelectrospray mass spectrometry: thermal stability and pathways for loss of bicarbonate from carbonic anhydrase II
From the themed collection: Analyst HOT Articles 2024
Paper

A zinc–air battery assisted self-powered electrochemical sensor for sensitive detection of microcystin-RR

Building a high-performance sensing platform is the key to developing sensitive sensors.

Graphical abstract: A zinc–air battery assisted self-powered electrochemical sensor for sensitive detection of microcystin-RR
From the themed collection: Analyst HOT Articles 2024
Paper

An activatable fluorescent-photoacoustic dual-modal probe for highly sensitive imaging of nitroxyl in vivo

A novel near-infrared fluorescent (NIRF) and photoacoustic (PA) dual-modal probe with enhanced sensitivity and a high PA signal-to-noise ratio was constructed for imaging HNO in vivo.

Graphical abstract: An activatable fluorescent-photoacoustic dual-modal probe for highly sensitive imaging of nitroxyl in vivo
From the themed collection: Analyst HOT Articles 2024
Paper

A label-free and immobilization-free approach for constructing photoelectrochemical nucleic acid sensors utilizing DNA–silver nanoparticle affinity interactions

This study presents a photoelectrochemical sensing platform for nucleic acid detection based on the on the varying protective effects of single-stranded DNA of different lengths against silver nanoparticles.

Graphical abstract: A label-free and immobilization-free approach for constructing photoelectrochemical nucleic acid sensors utilizing DNA–silver nanoparticle affinity interactions
From the themed collection: Analyst HOT Articles 2024
Paper

Multiphysics analytical and numerical studies of biomolecule preconcentration utilizing ion concentration polarization: a case study of convergent microchannels

A convergent sector in microfluidic devices utilizing ion concentration polarization (ICP) can help increase the preconcentration rate and the concentration enhancement factor (CEF) of biomolecules.

Graphical abstract: Multiphysics analytical and numerical studies of biomolecule preconcentration utilizing ion concentration polarization: a case study of convergent microchannels
From the themed collection: Analyst HOT Articles 2024
Paper

Rational design of NiO/Ti3C2Tx nanocomposites with enhanced triethylamine sensing performance

The fabricated NiO/Ti3C2Tx sensor exhibits a high response value of 950% to 50 ppm TEA with fast response/recovery times of 8/40 s.

Graphical abstract: Rational design of NiO/Ti3C2Tx nanocomposites with enhanced triethylamine sensing performance
From the themed collection: Analyst HOT Articles 2024
Open Access Paper

A pH-enhanced resolution in benchtop NMR spectroscopy

An alternative to serial NMR measurement on a benchtop machine exploits a pH gradient along the NMR tube and mechanical sample shifting. This approach allows one to detect and characterize “pH-sensitive” peaks.

Graphical abstract: A pH-enhanced resolution in benchtop NMR spectroscopy
From the themed collection: Analyst HOT Articles 2024
Paper

Efficacy of tyrosine kinase inhibitors examined by a combination of Raman micro-spectroscopy and a deep wavelet scattering-based multivariate analysis framework

Raman micro-spectroscopy is applied as a label-free analytical tool to monitor the efficacy and spatial distribution of tyrosine kinase inhibitors in cells. This method has a prospective in drug evaluation and presumably in drug discovery.

Graphical abstract: Efficacy of tyrosine kinase inhibitors examined by a combination of Raman micro-spectroscopy and a deep wavelet scattering-based multivariate analysis framework
From the themed collection: Analyst HOT Articles 2024
Paper

Determining the degree of chromosomal instability in breast cancer cells by atomic force microscopy

Detection of chromosomal instability in breast cancer cells with different malignancy degrees by AFM.

Graphical abstract: Determining the degree of chromosomal instability in breast cancer cells by atomic force microscopy
From the themed collection: Analyst HOT Articles 2024
Paper

Lectin-conjugated nanotags with high SERS stability: selective probes for glycans

Surface-enhanced Raman scattering (SERS) nanotags functionalized with lectins as the biological recognition element can be used to target the carbohydrate portion of carbohydrate-carrying molecules (glycoconjugates).

Graphical abstract: Lectin-conjugated nanotags with high SERS stability: selective probes for glycans
From the themed collection: Analyst HOT Articles 2024
Paper

Supersensitive detection of lincomycin with an ECL aptasensor based on the synergistic integration of gold-functionalized upconversion nanoparticles and thiolated 3,4,9,10-perylene tetracarboxylic acid

A supersensitive aptamer ECL sensor fabricated with UCNPs/Au and t-PTCA was used for lincomycin detection. The sensor exhibited excellent analytical performance with a wide linear range, low detection limit, high specificity and good application.

Graphical abstract: Supersensitive detection of lincomycin with an ECL aptasensor based on the synergistic integration of gold-functionalized upconversion nanoparticles and thiolated 3,4,9,10-perylene tetracarboxylic acid
From the themed collection: Analyst HOT Articles 2024
Paper

Advancing carbohydrate quantification in MALDI mass spectrometry by the rapidly freeze-drying droplet (RFDD) method

A simple and innovative sample preparation technique of MALDI significantly enhances the ion intensity and spatial uniformity for carbohydrates.

Graphical abstract: Advancing carbohydrate quantification in MALDI mass spectrometry by the rapidly freeze-drying droplet (RFDD) method
From the themed collection: Analyst HOT Articles 2024
Paper

A selective colorimetric and efficient removal strategy for mercury(II) in aquatic systems using mesoporous Fe3O4-loaded silver probes

Mesoporous Fe3O4-loaded silver nanocomposites (Fe3O4@Ag) were simply fabricated as bi-functional nanozymes for the catalysis-based detection and removal of Hg2+ ions.

Graphical abstract: A selective colorimetric and efficient removal strategy for mercury(ii) in aquatic systems using mesoporous Fe3O4-loaded silver probes
From the themed collection: Analyst HOT Articles 2024
Paper

Ag supraparticles with 3D hot spots to actively capture molecules for sensitive detection by surface enhanced Raman spectroscopy

3D supraparticles with non-close-packed structures are self-assembled through ultrasonic self-assembly at the liquid–liquid interface, and can actively capture molecules into hot spot areas to achieve highly sensitive detection by SERS.

Graphical abstract: Ag supraparticles with 3D hot spots to actively capture molecules for sensitive detection by surface enhanced Raman spectroscopy
From the themed collection: Analyst HOT Articles 2024
Paper

A chiral metal–organic framework/cyclodextrin sensing interface for the chiral discrimination of tryptophan enantiomers

A CMOF is synthesized by the grafting of carboxymethyl-β-CD to L-histidine-functionalized ZIF-8, which is used for the discrimination of tryptophan enantiomers.

Graphical abstract: A chiral metal–organic framework/cyclodextrin sensing interface for the chiral discrimination of tryptophan enantiomers
From the themed collection: Analyst HOT Articles 2024
Paper

Polymeric membrane potentiometric antibiotic sensors using computer-aided screening of supramolecular macrocyclic carriers

A polymeric membrane potentiometric antibiotic sensor using computationally screened supramolecular macrocyclic carriers by the molecular docking technique is described.

Graphical abstract: Polymeric membrane potentiometric antibiotic sensors using computer-aided screening of supramolecular macrocyclic carriers
From the themed collection: Analyst HOT Articles 2024
Paper

A COX2-targeting cancer-specific fluorescent probe for hydrogen sulfide detection in living cells, Caenorhabditis elegans, and zebrafish

A novel H2S-activated cancer-specific fluorescent probe COX2-H2S was rationally developed, with naphthalimide as the fluorophore and indomethacin as the targeting unit, for the imaging determination of H2S in living cells, C. elegans, and zebrafish.

Graphical abstract: A COX2-targeting cancer-specific fluorescent probe for hydrogen sulfide detection in living cells, Caenorhabditis elegans, and zebrafish
From the themed collection: Analyst HOT Articles 2024
Open Access Paper

Improved pH measurement of mobile phases in reversed-phase liquid chromatography

Mobile phase unified pH was investigated using several methods to provide pH values comparable between different mobile phase compositions. A double junction combined electrode filled with ionic liquid was tested for the first time.

Graphical abstract: Improved pH measurement of mobile phases in reversed-phase liquid chromatography
From the themed collection: Analyst HOT Articles 2024
Paper

Superassembled MXene–carboxymethyl chitosan nanochannels for the highly sensitive recognition and detection of copper ions

We demonstrate a freestanding MXene/carboxymethyl chitosan nanochannel (MXene/CMC) membrane by a simple super-assembly strategy, which can achieve highly sensitive and stable detection of Cu2+ ions with a limit of detection of 0.095 nM.

Graphical abstract: Superassembled MXene–carboxymethyl chitosan nanochannels for the highly sensitive recognition and detection of copper ions
From the themed collection: Analyst HOT Articles 2024
Paper

Cathodic electrochemiluminescence of L012 and its application in antioxidant detection

The mechanism for the generation of cathodic ECL by an L012–O2 system is unraveled. Then this cathodic ECL system is used for measuring the antioxidant capacity of commercial juice with Trolox as a standard.

Graphical abstract: Cathodic electrochemiluminescence of L012 and its application in antioxidant detection
From the themed collection: Analyst HOT Articles 2024
97 items - Showing page 1 of 2

About this collection

This themed collection features articles published in Analyst marked as HOT by the handling editor or as recommended by referees. Congratulations to all the authors whose articles are featured.

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