Themed collection 2024 Journal of Materials Chemistry B Lunar New Year

This review accounts recent advances in fabrication, supramolecular assembling, 3D printing of microgels, and their applications in cell culture, drug delivery, antibacterial and tissue engineering.

Metal–organic frameworks (MOFs) hold great promise for widespread applications in biomedicine and nanomedicine.

The binding of stem cells with a peptide-immobilized material surface, where several peptides are designed and conjugated on the material with multiple reactions, activates several signaling pathways that determine the stem cell fate.

Oxidative stress induced by the imbalance from periodontal pathogens is the main inducement for periodontal tissue destruction, and ROS scavenging biomaterials could be the promising candidate for periodontitis therapy.

SQR29 organophotosensitizer was encapsulated into poly(lignin/PEG/PPG urethane) to form a hydrogel (LSQR29), providing excellent antibacterial photodynamic therapy (aPDT) property to combat antibiotic-resistant pathogenic bacteria in wound infection.

Four gRNAs were synthesized and used to form ribonucleoproteins (RNPs) with tracRNA and dCas9-VPR, and were then immobilized on magnetic peptide-imprinted chitosan nanoparticles, which enhanced transfection for production of insulin.

A biodegradable self-powered bacterial sensor made of carbohydrate protein interaction. The sensor offers a simple design and capable for rapid and effective detection of E. coli bacteria.

The DOX@7FZ was able to enhance the ROS level in cancer cells via a synergistic effect between apoptosis/ferroptosis synergism.

Neurotransmitters have been of immense scientific interest due to their importance as human-health biomarkers.

The multifunctional theranostic cyanine SLCOOH, capable of real-time imaging of Aβ contents in vivo and targeting multiple pathological pathways or mechanisms of neurodegeneration, was unambiguously demonstrated.

A tunable fluorescent probe for superoxide anion detection during inflammation caused by Treponema pallidum.

This work reports the use of M-BDC (M = Cu, Mn, Ni, and Zr) MOFs for glucose sensing by surface plasmon resonance (SPR) methods. The sensitivity is in the order of Zr-BDC > Cu-BDC > Mn-BDC > Ni-BDC > bare Au chip.

The combination of ionizable lipids bearing alkyl chains and fluorinated alkyl chains improves the cellular uptake and mRNA expression of lipid nanoparticles.

Combined chemo-immuno-photothermal therapy based on ursolic acid/astragaloside IV-loaded hyaluronic acid-modified polydopamine nanomedicine is a promising strategy for the treatment of non-small cell lung cancer (NSCLC) metastasis.

By incorporating [NiFe]-hydrogenases into a proteinaceous carboxysome shell, we generate a novel biocatalyst that has improved production of clean hydrogen, oxygen tolerance, and thermostability, highlighting its great potential in biotechnological applications.

A schematic diagram of the gAu–CuS HSs hydrogel for treating diabetic wound healing. In situ injection of gAu–CuS HSs hydrogels programmed to promote multiple stages of the wound healing process.

In this work, the integration of the desirable hyperbolic microfluidic chip with chemiluminescence as a signal readout enabled achieving the point-of-care testing of PCT in clinical diagnosis and treatment.

Cancer-associated fibroblasts (CAFs) produce a critical tumor-promoting effect by cellular crosstalk with cancer cells and remodel the extracellular matrix (ECM) to form a protective physical barrier.

A cationic micellar drug delivery system was found to significantly enhance the intra-cartilage penetration and retention capability due to the electrostatic interaction between the micelles and the negatively charged cartilage extracellular matrix.

Silk fibroin (SF) has caught interest in tissue engineering owing to their biocompatibility and biodegradability.

A biomaterial scaffold capable of simultaneously loading multiple stem cells for potential neuralized bone regeneration.

Lipase immobilized on an ionic liquid modified magnetic Cu-based metal–organic framework with enhanced catalytic performance in the synthesis of isoamyl acetate.

Intracellular working mechanism of Gem-loaded MBPF CSNPs when exposed to NIR laser irradiation. MBPF passively targets and enhances ROS generation and DNA damage within MDA-MB-231 cells through their dual performance.

3D printed mussel-inspired polydopamine-coated β-TCP/polycaprolactone scaffolds have been considered potential grafts that facilitated not only the physicochemical behaviors but also stimulated the formation of neo-bone tissue in femur defects.