Jump to main content
Jump to site search

Themed collection 2018 Journal of Materials Chemistry B HOT Papers

44 items
Review Article

Development of quantum dot-based biosensors: principles and applications

We review the recent advances in quantum dot-based biosensors and focus on quantum dot-based fluorescent, bioluminescent, chemiluminescent, and photoelectrochemical biosensors.

Graphical abstract: Development of quantum dot-based biosensors: principles and applications
Review Article

Biodegradable polyester unimolecular systems as emerging materials for therapeutic applications

Biodegradable polyester unimolecular systems are the future emerging materials for therapeutic applications.

Graphical abstract: Biodegradable polyester unimolecular systems as emerging materials for therapeutic applications
Review Article

Approaches to improve the biocompatibility and systemic circulation of inorganic porous nanoparticles

The exploitation of various inorganic nanoparticles as drug carriers and therapeutics is becoming increasingly common.

Graphical abstract: Approaches to improve the biocompatibility and systemic circulation of inorganic porous nanoparticles
Review Article

Tuning the optical properties of graphene quantum dots for biosensing and bioimaging

This review highlights new insights into the various strategies used to tune the optical features of graphene quantum dots, and their use as attractive and powerful probes for bio-sensing/imaging.

Graphical abstract: Tuning the optical properties of graphene quantum dots for biosensing and bioimaging
Review Article

Recent advances in nitric oxide delivery for antimicrobial applications using polymer-based systems

The present review highlights the recent developments in NO-releasing polymeric biomaterials for antimicrobial applications.

Graphical abstract: Recent advances in nitric oxide delivery for antimicrobial applications using polymer-based systems
Review Article

Combined therapies with nanostructured carbon materials: there is room still available at the bottom

Combining therapies on a sheet of carbon is possible!

Graphical abstract: Combined therapies with nanostructured carbon materials: there is room still available at the bottom
Communication

Photostable and biocompatible AIE-active conjugated polyelectrolytes for efficient heparin detection and specific lysosome labelling

A series of new conjugated polyelectrolytes (CPEs) with emissive tetraphenylethene-containing backbones and specific targeting pendants are synthesized and characterized.

Graphical abstract: Photostable and biocompatible AIE-active conjugated polyelectrolytes for efficient heparin detection and specific lysosome labelling
Communication

A long-lifetime iridium(III) complex for lysosome tracking with high specificity and a large Stokes shift

Investigating the role of lysosome dysfunction in cancer requires the development of efficient probes for lysosomes.

Graphical abstract: A long-lifetime iridium(iii) complex for lysosome tracking with high specificity and a large Stokes shift
Paper

Tunable fabrication of new theranostic Fe3O4-black TiO2 nanocomposites: dual wavelength stimulated synergistic imaging-guided phototherapy in cancer

The development of a simplified theranostic system with high-efficiency for multifunctional imaging-guided photodynamic therapy/photothermal therapy (PDT/PTT) is a great challenge.

Graphical abstract: Tunable fabrication of new theranostic Fe3O4-black TiO2 nanocomposites: dual wavelength stimulated synergistic imaging-guided phototherapy in cancer
Paper

Dual-readout aptasensing of antibiotic residues based on gold nanocluster-functionalized MnO2 nanosheets with target-induced etching reaction

In this study, we designed a novel dual-readout biosensing protocol for quantitative or qualitative screening of antibiotic residues (Kanamycin; Kana used in this case) using a spectrofluorometer and via naked-eye detection.

Graphical abstract: Dual-readout aptasensing of antibiotic residues based on gold nanocluster-functionalized MnO2 nanosheets with target-induced etching reaction
Paper

Lipid bilayer modified gold nanorod@mesoporous silica nanoparticles for controlled drug delivery triggered by near-infrared light

We coupled the photothermal and thermoresponsive properties in one nanoplatform by wrapping AuNRs@mSiO2 with thermoresponsive lipid bilayer.

Graphical abstract: Lipid bilayer modified gold nanorod@mesoporous silica nanoparticles for controlled drug delivery triggered by near-infrared light
Paper

A polymer-free, biomimicry drug self-delivery system fabricated via a synergistic combination of bottom-up and top-down approaches

A pure drug self-delivery system with a cell membrane modified to create a unique class of ideal drug delivery platforms.

Graphical abstract: A polymer-free, biomimicry drug self-delivery system fabricated via a synergistic combination of bottom-up and top-down approaches
Paper

Developing a pH-sensitive Al(OH)3 layer-mediated UCNP@Al(OH)3/Au nanohybrid for photothermal therapy and fluorescence imaging in vivo

A pH-responsive and hydrophilic Al(OH)3 mediating layer makes possible the promising integration of photothermal therapy and fluorescence imaging based on upconversion nanoparticles (UCNPs).

Graphical abstract: Developing a pH-sensitive Al(OH)3 layer-mediated UCNP@Al(OH)3/Au nanohybrid for photothermal therapy and fluorescence imaging in vivo
Paper

Dual antibacterial behavior of a curcumin–upconversion photodynamic nanosystem for efficient eradication of drug-resistant bacteria in a deep joint infection

The curcumin–upconversion photodynamic nanosystem exhibits dual antibacterial behavior for MRSA-induced periprosthetic joint infection under NIR irradiation.

Graphical abstract: Dual antibacterial behavior of a curcumin–upconversion photodynamic nanosystem for efficient eradication of drug-resistant bacteria in a deep joint infection
Paper

A novel label-free photoelectrochemical immunosensor based on NCQDs and Bi2S3 co-sensitized hierarchical mesoporous SnO2 microflowers for detection of NT-proBNP

A novel label-free PEC immunosensor based on NCQDs and Bi2S3 co-sensitized hierarchical mesoporous SnO2 microflowers was developed for NT-proBNP detection.

Graphical abstract: A novel label-free photoelectrochemical immunosensor based on NCQDs and Bi2S3 co-sensitized hierarchical mesoporous SnO2 microflowers for detection of NT-proBNP
Paper

Self-immolative polymers with potent and selective antibacterial activity by hydrophilic side chain grafting

Self-immolative polymers, which exert potent antibacterial activity with low hemolytic toxicity to red blood cells, are triggered to unzip into small molecules by a chemical stimulus.

Graphical abstract: Self-immolative polymers with potent and selective antibacterial activity by hydrophilic side chain grafting
Paper

Light-driven self-powered biosensor for ultrasensitive organophosphate pesticide detection via integration of the conjugated polymer-sensitized CdS and enzyme inhibition strategy

A new light-driven self-powered biosensor based on a photoelectrochemical enzymatic fuel cell was proposed for the ultrasensitive detection of organophosphate pesticides.

Graphical abstract: Light-driven self-powered biosensor for ultrasensitive organophosphate pesticide detection via integration of the conjugated polymer-sensitized CdS and enzyme inhibition strategy
Paper

Poly(ester amide)-based hybrid hydrogels for efficient transdermal insulin delivery

Transdermal drug delivery is an attractive, non-invasive treatment.

Graphical abstract: Poly(ester amide)-based hybrid hydrogels for efficient transdermal insulin delivery
Paper

Porous nanosheet wrapping for live imaging of suspension cells

We propose a porous nanosheet (ultrathin polymer film) wrapping method to noninvasively immobilize suspension cells for their live imaging.

Graphical abstract: Porous nanosheet wrapping for live imaging of suspension cells
Paper

Durable, flexible, superhydrophobic and blood-repelling surfaces for use in medical blood pumps

A new sand-casting method for fabricating superhydrophobic materials gives highly durable, flexible, and blood-repelling surfaces useful for cardiovascular medical devices.

Graphical abstract: Durable, flexible, superhydrophobic and blood-repelling surfaces for use in medical blood pumps
Paper

Fabrication of micron-sized BSA-imprinted polymers with outstanding adsorption capacity based on poly(glycidyl methacrylate)/polystyrene (PGMA/PS) anisotropic microspheres

Monodisperse poly(glycidyl methacrylate)/polystyrene (PGMA/PS) anisotropic microspheres have been fabricated by seed polymerization for BSA-imprinting microspheres.

Graphical abstract: Fabrication of micron-sized BSA-imprinted polymers with outstanding adsorption capacity based on poly(glycidyl methacrylate)/polystyrene (PGMA/PS) anisotropic microspheres
Paper

Multifunctional magnetic particles for effective suppression of non-specific adsorption and coimmobilization of multiple enzymes by DNA directed immobilization

Zwitterion-functionalized magnetic particles can efficiently suppress non-specific adsorption of enzymes and can be used for coimmobilization of multienzymes by DNA directed immobilization.

Graphical abstract: Multifunctional magnetic particles for effective suppression of non-specific adsorption and coimmobilization of multiple enzymes by DNA directed immobilization
Paper

Multifunctional carbon dot for lifetime thermal sensing, nucleolus imaging and antialgal activity

The electrochemical synthesis of multifunctional carbon dots, that are used for a fluorescence-based nanothermometers, nucleolus probe and antialgal agents.

Graphical abstract: Multifunctional carbon dot for lifetime thermal sensing, nucleolus imaging and antialgal activity
Paper

Regulation of mesenchymal stem cell functions by micro–nano hybrid patterned surfaces

Regulation of cell alignment, elongation and differentiation of hMSCs by micro–nano hybrid patterns.

Graphical abstract: Regulation of mesenchymal stem cell functions by micro–nano hybrid patterned surfaces
Paper

Surface zwitterionization on versatile hydrophobic interfaces via a combined copolymerization/self-assembling process

A special surface modification for coating amphiphilic zwitterionic polymers in a single step for antifouling applications in complex media.

Graphical abstract: Surface zwitterionization on versatile hydrophobic interfaces via a combined copolymerization/self-assembling process
Paper

A highly hemocompatible erythrocyte membrane-coated ultrasmall selenium nanosystem for simultaneous cancer radiosensitization and precise antiangiogenesis

Herein we design a highly hemocompatible erythrocyte membrane-coated ultrasmall selenium nanosystem for simultaneous cancer radiosensitization and precise antiangiogenesis.

Graphical abstract: A highly hemocompatible erythrocyte membrane-coated ultrasmall selenium nanosystem for simultaneous cancer radiosensitization and precise antiangiogenesis
Paper

Hierarchical nanocomposites of graphene oxide and PEGylated protoporphyrin as carriers to load doxorubicin hydrochloride for trimodal synergistic therapy

We report a supramolecular hierarchical nanocomposite for combination photodynamic, photothermal, and chemotherapy.

Graphical abstract: Hierarchical nanocomposites of graphene oxide and PEGylated protoporphyrin as carriers to load doxorubicin hydrochloride for trimodal synergistic therapy
Paper

Highly sensitive fluorescence quantification of intracellular telomerase activity by repeat G-rich DNA enhanced silver nanoclusters

As an important biomarker for early cancer diagnosis and a valuable therapeutic target, the detection and monitoring of telomerase activity has attracted extensive attention.

Graphical abstract: Highly sensitive fluorescence quantification of intracellular telomerase activity by repeat G-rich DNA enhanced silver nanoclusters
Paper

Growth factor-free salt-leached silk scaffolds for differentiating endothelial cells

Various kinetic factors were introduced into a traditional salt-leached process to prepare silk scaffolds with tunable mechanical properties and vascularisation capacity.

Graphical abstract: Growth factor-free salt-leached silk scaffolds for differentiating endothelial cells
Paper

Unraveling the molecular mechanisms of thermo-responsive properties of silk-elastin-like proteins by integrating multiscale modeling and experiment

Adaptive hydrogels tailor-made from silk-elastin-like proteins (SELPs) possess excellent biocompatibility and biodegradability with properties that are tunable and responsive to multiple simultaneous external stimuli.

Graphical abstract: Unraveling the molecular mechanisms of thermo-responsive properties of silk-elastin-like proteins by integrating multiscale modeling and experiment
Paper

PLGA-based nanofibers with a biomimetic polynoradrenaline sheath for rapid in vivo sampling of tetrodotoxin and sulfonamides in pufferfish

PLGA nanofibers with PNA sheath modification achieve enhanced extraction performance and antibiofouling capacity for in vivo sampling in pufferfish.

Graphical abstract: PLGA-based nanofibers with a biomimetic polynoradrenaline sheath for rapid in vivo sampling of tetrodotoxin and sulfonamides in pufferfish
Paper

Long-term delivery of rhIGF-1 from biodegradable poly(lactic acid)/hydroxyapatite@Eudragit double-layer microspheres for prevention of bone loss and articular degeneration in C57BL/6 mice

Insulin-like growth factor (IGF-1) has encouraged researchers to investigate its various potential therapeutic uses such as in the treatment of osteoporosis and repair of articular cartilage.

Graphical abstract: Long-term delivery of rhIGF-1 from biodegradable poly(lactic acid)/hydroxyapatite@Eudragit double-layer microspheres for prevention of bone loss and articular degeneration in C57BL/6 mice
Paper

Nano-sized paramagnetic and fluorescent fluorinated carbon fiber with high NIR absorbance for cancer chemo-photothermal therapy

We report a novel strategy to synthesize nano-sized, water-soluble and functionalized fluorinated carbon fiber oxide with high fluorescence, paramagnetism and NIR absorption for cancer chemo-photothermal therapy.

Graphical abstract: Nano-sized paramagnetic and fluorescent fluorinated carbon fiber with high NIR absorbance for cancer chemo-photothermal therapy
Paper

Exosomes separated based on the “STOP” criteria for tumor-targeted drug delivery

A new exosome-related drug delivery vehicle was explored based on the “STOP” criteria, dramatically promoting the clinical translation of exosomes.

Graphical abstract: Exosomes separated based on the “STOP” criteria for tumor-targeted drug delivery
Paper

Triple therapy of hepatocellular carcinoma with microRNA-122 and doxorubicin co-loaded functionalized gold nanocages

A combination of different therapy strategies has great potential to efficaciously treat malignant tumors, by virtue of their synergetic effects.

Graphical abstract: Triple therapy of hepatocellular carcinoma with microRNA-122 and doxorubicin co-loaded functionalized gold nanocages
Paper

The in vivo fates of plant viral nanoparticles camouflaged using self-proteins: overcoming immune recognition

Nanoparticle camouflage with serum albumin is formulation specific, does not produce antibodies against the coating, and shields nanoparticle antibody recognition.

Graphical abstract: The in vivo fates of plant viral nanoparticles camouflaged using self-proteins: overcoming immune recognition
Paper

Marriage of artificial catalase and black phosphorus nanosheets for reinforced photodynamic antitumor therapy

Pt nanoparticle-based artificial catalase is decorated on black phosphorus nanosheets, achieving reinforced photodynamic antitumor performance.

Graphical abstract: Marriage of artificial catalase and black phosphorus nanosheets for reinforced photodynamic antitumor therapy
Paper

Thermoresponsive double network cryogels from dendronized copolymers showing tunable encapsulation and release of proteins

Thermoresponsive double network cryogels were prepared from OEG-based dendronized copolymers with PVA, which can reversibly capture and release proteins.

Graphical abstract: Thermoresponsive double network cryogels from dendronized copolymers showing tunable encapsulation and release of proteins
Paper

Time-lapse live cell imaging to monitor doxorubicin release from DNA origami nanostructures

DNA origami nanostructures can serve as a promising carrier for drug delivery due to the outstanding programmability and biocompatibility.

Graphical abstract: Time-lapse live cell imaging to monitor doxorubicin release from DNA origami nanostructures
Paper

Size-controllable dual drug-loaded silk fibroin nanospheres through a facile formation process

Paclitaxel/doxorubicin-loaded silk fibroin nanospheres were prepared through a facile and green method and showed a synergistic effect on the anti-proliferative activity.

Graphical abstract: Size-controllable dual drug-loaded silk fibroin nanospheres through a facile formation process
Paper

Fabrication of gelatin-micropatterned surface and its effect on osteogenic differentiation of hMSCs

Micropatterned surface with different surface chemistries was fabricated for the direct comparison of their effect on the behaviors of hMSCs and to avoid any batch to batch variations during cell culture.

Graphical abstract: Fabrication of gelatin-micropatterned surface and its effect on osteogenic differentiation of hMSCs
Paper

Transglutaminase mediated PEGylation of nanobodies for targeted nano-drug delivery

The PEGylation of anti-EGFR nanobodies was achieved via a transglutaminase catalyzed reaction through a Q-tag. The nanobody tethered drug delivery system exhibits superior specificity to EGFR positive tumor cells.

Graphical abstract: Transglutaminase mediated PEGylation of nanobodies for targeted nano-drug delivery
Paper

Integration of antifouling and antibacterial properties in salt-responsive hydrogels with surface regeneration capacity

A new design for a new multifunctional hydrogel that integrates antimicrobial, antifouling, and surface regeneration properties for antimicrobial applications.

Graphical abstract: Integration of antifouling and antibacterial properties in salt-responsive hydrogels with surface regeneration capacity
Paper

A highly sensitive and rapidly responding fluorescent probe based on a rhodol fluorophore for imaging endogenous hypochlorite in living mice

A novel fluorescent probe RO610 was applied for the in vivo detection of endogenous ClO using living mice.

Graphical abstract: A highly sensitive and rapidly responding fluorescent probe based on a rhodol fluorophore for imaging endogenous hypochlorite in living mice
44 items

About this collection

This on-going web collection features all the articles published in Journal of Materials Chemistry B in 2018 marked as HOT, as recommended by referees.  Congratulations to all the authors whose articles are featured!

Spotlight

Advertisements