Themed collection ChemComm Most Popular 2025 Articles

Developments in the synthesis and application of strained spiro heterocycles are discussed, given their potential as non-classical rigid three-dimensional bioisosteres in drug development.

This brief review highlights a promising approach for inhibiting Aβ oligomerization, which involves unnatural foldamers that interact with Aβ to prevent further aggregation.

This review examines LDHs as UOR electrocatalysts a key process in urea-assisted hydrogen production. It discusses their limitations and explores strategies for performance enhancement of LDHs. Future research directions are also highlighted.

This review systematically depicts the theoretical models for Li deposition, the mechanisms and formation conditions of spherical Li and the advantages of combining Li spheres with 3D conductive frameworks.

Proton conductivity of copper-based MOFs can be enhanced by incorporating polyoxometalates, hydrogen-bonded guest molecules, functionalized organic linkers, and acid-functionalized polymers.

This review highlights the role of polymer and composite materials in advancing the green hydrogen economy, supporting a low-carbon future, and outlines future research directions.

Bio-based vitrimers represent a green and sustainable bridge between thermoplastics and thermosets.

This accounts reviews several structural reassignments of complex natural products that were inspired by meroterpenoid biosynthetic logic and proven by biomimetic total synthesis.

This article summarizes the latest advances and future prospects of single-atom electrocatalysts for urea synthesis.

Cycloparaphenylenes (CPPs) possess a promising radial π-system with size-dependent photophysics and a unique curved cavity, facilitating their utility in chiral materials, supramolecular chemistry, and optoelectronic devices.

The recent progress in synthesis methods and improvement strategies of advanced TMS-based electrodes for supercapacitors is summarized.

Different operando characterization techniques for the time-dependent screening of SACs under working conditions and the electrochemical CO₂RR applications of SAC-derived materials have been reviewed.

The growing perovskite solar cells (PSC) have reached a power conversion efficiency of up to 25% within a decade and demonstrated the potential to replace traditional silicon-based solar cells.

The MXene-transition metal chalcogenide hybrid materials are presented for supercapacitor applications with significant discussion towards their theoretical aspects.

This article covers the developments and outlook in auxiliary assisted C–H functionalization with vinylcyclopropanes and cyclopropanols utilizing transition-metal-catalysis.

This article reviews recent advances in the chemistry of structurally constrained cationic P(III) compounds, focusing on their ability to mimic transition metal behavior in small molecule activation and catalysis.

Direct seawater electrolysis presents a promising solution to address both freshwater scarcity and the growing demand for green hydrogen in regions abundant in renewable energy.

Synthesis of unnatural indoles and indolines as key steps in the total synthesis of complex natural products, a recent review.

BiVO₄-based heterostructures enhance photocatalysis via improved charge separation, light absorption, and kinetics for sustainable energy applications, including water splitting, CO₂ reduction, and pollutant degradation.

This feature article summarizes the recent developments of azahelicenes showing circularly polarized luminescence.

This review identifies COFs as promising materials for radioactive iodine adsorption, and highlights how structural and functional modifications, including electron-rich, flexible, ionic COFs and COF nanosheets significantly enhance iodine capture.

The integration of a bilayer SSE with pre-lithiated metal anodes facilitates the development of high-performance ASSLMBs with enhanced cycling stability.

Developing photoactive molecules represents an emerging strategy for temporally regulated inhibition of the indoleamine 2,3-dioxygenase 1 (IDO1) enzyme.

A heterojunction photocatalyst, NiMoO₄/Mg-Al layered-double hydroxide (LDH), was synthesized for simultaneous chloramphenicol degradation and Cr(VI) reduction under visible light.

Titanium complexes supported by tris(pyrazolyl)borate and alkoxide/aryloxide ligands catalyse N₂ silylation.

A lateral flow assay platform based on a triple cascade amplification system integrated recombinase polymerase amplification, CRISPR/Cas12a, and catalytic hairpin assembly for simultaneous detection of Mycoplasma pneumoniae and H1N1.

A photo-induced three-component reaction of quinoxalin-2(1H)-ones with unactivated alkenes and fluoroalkyl bromides has been developed. This transformation was initiated by the photochemistry of electron donor acceptor (EDA) complexes.

We have developed a direct photochemical cross-esterification of alcohols that proceeds via the in situ generation of acyl bromides.

We report the development of a continuous flow approach to nitrogen atom insertion.

Herein, we report a mild and efficient cobalt-catalyzed electrochemical method for the regioselective C–H acyloxylation of aromatic and vinylic amides, utilizing 8-aminoquinoline as the directing group.

Transition metal salen complexes (Co, Ni, Cu) are studied as precatalysts for CO₂-to-CO electroreduction in zero-gap electrolyzers.

A photo-induced Ru-catalyzed C(sp²)–H arylation of heterocycle-tethered alkenes to access to tri-substituted alkenes under mild conditions with broad functional group tolerance, including bio-relevant motifs, is reported.

We show that low-frequency audible sound drives the crystallisation of distinct solid forms of organic compounds in solution crystallisation.

Sliding angles of polar and nonpolar droplets on well-defined surfaces, formed by adsorption of self-assembled monolayers from solutions containing binary mixtures of alkanethiols, depend on the contact-angle hysteresis but not the work of adhesion.

Tuning the optoelectronic properties of hexaarenes with main-group elements: phosphorus boosts fluorescence in solution, silicon maximizes solid-state emission, and nitrogen narrows the bandgap.

Rh/Sb co-doped SrTiO₃ with {100}/{110} crystal facet exposure is synthesized, achieving spatial charge separation under visible light irradiation, which significantly enhances charge separation efficiency and improves photocatalytic performance.

This study presents the first interrupted Corey–Chaykovsky reaction of α,β-ynones, uncovering a novel mechanistic feature and enabling the synthesis of unprecedented polycyclic architectures.

This work communicates the tunability of dynamic properties and closed-loop recyclability of the cross-linked polymers using dynamic ether linkages.

Co²⁺/Ni²⁺/Cu²⁺-intercalated hydrated V₂O₅ nanosheets were first synthesized via a novel self-assembly approach and exhibit excellent performance in AZIBs.

Design of unsymmetrical bis(anilido)xanthene ligands – harnessing the power of a transient magnesium(I) complex in benzene activation.

Direct decarboxylative sulfinamidation of aliphatic carboxylic acids via a photoinduced iron-mediated ligand-to-metal charge-transfer process was reported.

Using collision-induced dissociation mass spectrometry and density functional theory, we assess the energetics of polymetallic [Cr₇NiF₈(O₂CR)₁₆]⁻ anions in vacuo, showing how the carboxylate influences the ring stability.

Visible-light photoredox catalyzed 1,2-arylalkylation of alkenes with quinoxalin-2(1H)-ones and malonic esters has been developed through direct C(sp²)–H/C(sp³)–H functionalization under mild conditions.

A ¹⁹F NMR spectroscopic probe, p-fluorobenzonitrile, is used to evaluate the relative Lewis acidity of boranes.

A benzene-based annihilator and a high triplet energy sensitizer were combined in an upconversion scheme, emitting photons with unprecedented energy.

The nanoneedle array of heterostructured RuO₂–Co₃O₄ promotes the oxidation activity of water through the synergy of tip-effect-induced OH⁻ enrichment, superior hydrophilicity and heterojunction-enhanced electron transfer.

A gold(I) complex with a phosphino-type ligand can simultaneously show AIE and high-contrast tricolored mechanofluorochromism for the first time, and its application in inkless writing information storage is developed.

Findings from in situ neutron diffraction are used to reduce processing times, yielding TiNiCu_0.03Sn samples with zT = 0.9 from powder precursors.

The all-solid-state Z-scheme Ag/AgCl/GCNT heterojunction possesses enhanced photocatalytic CO₂ reduction performance with 100% CO selectivity.

The mechanism of acid catalysed polyethylene cracking is investigated using a combination of infrared spectroscopy and inelastic neutron scattering measurements.

A complete series of CsPb(Cl_xBr_1−x)₃ mixed-halide perovskites with x = 0–1 in small steps is reported, and their structural and optical properties characterised. All data is accessible in a machine-readable format.

We propose a novel computational method to predict the crystal structures of bowl-shaped π-conjugated molecules and to reproduce their assembly structure from randomly dispersed molecules using all-atom molecular dynamics (MD) simulation.

An alkene-terminated ligand self-assembles with rare-earth ions, yielding polymerizable cages and subsequently rare-earth-binding polymer networks.

Structure–reactivity relationships were identified for a series of norbornene derivatives that facilitated rapid light-induced thiol–ene polymerizations for hydrogel 3D printing.

MoS₂ nanosheet-supported Rh nanoclusters were synthesized via molten salt electrolysis followed by wet chemical reduction for high-performance electrocatalytic hydrogen evolution.

The addition of the rGO enhances the electronic conductivity of NaVPO₄F, offering remarkable rate capability and long cycling performance.

The interfaces between the perovskite and charge-transporting layers typically exhibit high defect concentrations, which are the primary cause of open-circuit voltage loss.

The leaching dynamics of the Ag–S interface and mechanism of CO₂ electroreduction for the Ag₂₅(SR)₁₈ nanocluster differ significantly from those for its Au₂₅(SR)₁₈ analogue.

Mo-doped PdIn bimetallene nanoribbons with regulated electronic structure were synthesized and demonstrated enhanced activity for ambient electrosynthesis of urea.

Schematic representation of Ti₃C₂T_x MXene synthesized via ultrafast microwave assisted method.