Themed collection Journal of Materials Chemistry B HOT Papers

109 items - Showing page 1 of 2
Perspective

Nanoparticle-mediated surfactant therapy in patients with severe COVID-19: a perspective

Nanoparticle-mediated surfactant therapy in patients with severe COVID-19.

Graphical abstract: Nanoparticle-mediated surfactant therapy in patients with severe COVID-19: a perspective
From the themed collection: Journal of Materials Chemistry B HOT Papers
Review Article

Gas and gas-generating nanoplatforms in cancer therapy

Gas-generating nanoplatforms have promising therapeutic potential for cancer treatment.

Graphical abstract: Gas and gas-generating nanoplatforms in cancer therapy
Review Article

SARS-CoV-2 and approaches for a testing and diagnostic strategy

The COVID-19 pandemic has led to an unprecedented global health challenge, creating sudden, massive demands for diagnostic testing, treatment, therapies, and vaccines.

Graphical abstract: SARS-CoV-2 and approaches for a testing and diagnostic strategy
Review Article

Nanotechnology lights up the antitumor potency by combining chemotherapy with siRNA

This review summarizes the latest nanosystems with different functional nanomaterials that co-load and protect the siRNA/drugs, precisely target tumors, and release cargoes intelligently.

Graphical abstract: Nanotechnology lights up the antitumor potency by combining chemotherapy with siRNA
Review Article

Superoxide dismutase nanozymes: an emerging star for anti-oxidation

This review summarizes catalytic mechanisms, regulatory factors, measurement methods and various applications of SOD-like nanozymes, as well as proposes the current challenges and prospects in the development of SOD-like nanozymes.

Graphical abstract: Superoxide dismutase nanozymes: an emerging star for anti-oxidation
From the themed collection: Journal of Materials Chemistry B HOT Papers
Review Article

Bringing naturally-occurring saturated fatty acids into biomedical research

This review introduces naturally-occurring saturated fatty acids (NSFAs) and their biomedical applications, including controlled drug release, targeted drug delivery, cancer therapy, antibacterial treatment, and tissue engineering.

Graphical abstract: Bringing naturally-occurring saturated fatty acids into biomedical research
From the themed collection: Journal of Materials Chemistry B HOT Papers
Review Article

Hyaluronic acid-based hydrogels to study cancer cell behaviors

Hyaluronic acid (HA) based hydrogels can be fabricated using various chemistries to study cancer cell behaviors in vitro.

Graphical abstract: Hyaluronic acid-based hydrogels to study cancer cell behaviors
From the themed collection: Journal of Materials Chemistry B HOT Papers
Review Article

2D materials as a diagnostic platform for the detection and sensing of the SARS-CoV-2 virus: a bird's-eye view

This article reviews the use of two-dimensional materials as diagnostic platforms for the detection and sensing of the SARS-CoV-19 virus.

Graphical abstract: 2D materials as a diagnostic platform for the detection and sensing of the SARS-CoV-2 virus: a bird's-eye view
Review Article

Magnetic nanocomplexes for gene delivery applications

This review paper covers the recent progress of magnetic nanoparticles (MNP)-based gene delivery. Cutting-edge applications of MNP-based gene delivery on cancer therapy, neural repairing, regenerative medicine and gene editing are also introduced.

Graphical abstract: Magnetic nanocomplexes for gene delivery applications
Review Article

Tissue adhesive hydrogel bioelectronics

This review describes the recent progress in tissue adhesive hydrogel bioelectronics.

Graphical abstract: Tissue adhesive hydrogel bioelectronics
Review Article

Nanoscale metal–organic frameworks for tumor phototherapy

Nanoscale metal–organic frameworks (NMOFs) based on different metal ions for phototherapy.

Graphical abstract: Nanoscale metal–organic frameworks for tumor phototherapy
Review Article

Biomaterial-based physical regulation of macrophage behaviour

Macrophages respond to physical stimuli of biomaterials, including stiffness, topography and confinement. Understanding the mechanical regulation of macrophage behaviour provides insights for biomaterial design.

Graphical abstract: Biomaterial-based physical regulation of macrophage behaviour
Review Article

Recent advances in thermo-sensitive hydrogels for drug delivery

Thermo-sensitive hydrogels based on different polymers have been broadly used in the pharmaceutical fields. In this review, the state-of-the-art thermo-sensitive hydrogels for drug delivery are elaborated

Graphical abstract: Recent advances in thermo-sensitive hydrogels for drug delivery
Review Article

Multifunctional conductive hydrogels and their applications as smart wearable devices

Multifunctional conductive hydrogels with representative preparation strategies and related properties.

Graphical abstract: Multifunctional conductive hydrogels and their applications as smart wearable devices
Review Article

Recent advances in enzymeless-based electrochemical sensors to diagnose neurodegenerative diseases

This review summarizes the research works of non-enzymatic electrochemical sensors for the early diagnosis of Neurodegenerative disease.

Graphical abstract: Recent advances in enzymeless-based electrochemical sensors to diagnose neurodegenerative diseases
Review Article

Mesoporous TiO2-based architectures as promising sensing materials towards next-generation biosensing applications

This review highlights the recent development of mesoporous TiO2-based architectures as promising sensing materials for diagnosing diseases and detecting harmful substances in the human body.

Graphical abstract: Mesoporous TiO2-based architectures as promising sensing materials towards next-generation biosensing applications
Review Article

The study and application of biomolecules in deep eutectic solvents

Deep eutectic solvents offer stimulating possibilities for biomolecular stabilization and manipulation, biocatalysis, bioextraction, biomass processing, and drug delivery and therapy.

Graphical abstract: The study and application of biomolecules in deep eutectic solvents
Review Article

A review on hydroxyapatite coatings for the biomedical applications: experimental and theoretical perspectives

The production of hydroxyapatite (HAP) composite coatings has continuously been investigated for bone tissue applications during the last few decades due to their significant bioactivity and osteoconductivity.

Graphical abstract: A review on hydroxyapatite coatings for the biomedical applications: experimental and theoretical perspectives
Review Article

Metal–ligand coordination nanomaterials for radiotherapy: emerging synergistic cancer therapy

This review summarizes the recent advances in metal-ligand coordination nanomaterials-mediated synergistic radiotherapy with a emphasis focusing upon constructive strategies for radiosensitive nanoplatform and underlying synergistic mechanism.

Graphical abstract: Metal–ligand coordination nanomaterials for radiotherapy: emerging synergistic cancer therapy
Communication

Citrate-based mussel-inspired magnesium whitlockite composite adhesives augmented bone-to-tendon healing

Citrate-based mussel-inspired magnesium whitlockite composite adhesives were developed to augment bone-to-tendon healing, by providing interface adhesion, promoting bony inward growth from the bone tunnel, and enhancing chondrogenesis and osteogenesis of the bone–tendon interface.

Graphical abstract: Citrate-based mussel-inspired magnesium whitlockite composite adhesives augmented bone-to-tendon healing
From the themed collection: Journal of Materials Chemistry B HOT Papers
Communication

Impact of molecular rigidity on the gene delivery efficiency of core–shell tecto dendrimers

Core–shell tecto dendrimers with improved core rigidity can be synthesized using phosphorus dendrimers as cores for enhanced gene delivery applications.

Graphical abstract: Impact of molecular rigidity on the gene delivery efficiency of core–shell tecto dendrimers
From the themed collection: Journal of Materials Chemistry B HOT Papers
Communication

A robust CRISPR–Cas12a biosensor coated with metal–organic framework

A protective coating strategy based on metal–organic frameworks (MOFs) has been proposed to preserve the bioactivity of the Cas12a/crRNA complex.

Graphical abstract: A robust CRISPR–Cas12a biosensor coated with metal–organic framework
From the themed collection: Journal of Materials Chemistry B HOT Papers
Communication

Hemoglobin coated oxygen storage metal–organic framework as a promising artificial oxygen carrier

A novel oxygen carrier with excellent oxygen storage capacity and sustained release ability has been synthesized. This hybrid may have potential to be developed as useful artificial oxygen carriers in the future.

Graphical abstract: Hemoglobin coated oxygen storage metal–organic framework as a promising artificial oxygen carrier
From the themed collection: Journal of Materials Chemistry B HOT Papers
Communication

Charge-reversal silver clusters for targeted bacterial killing

Ag(−)/Ag(+) clusters with negatively charged nanoparticles and big-size are transformed into positively charged nanoparticles with small size in a bacterial acidic environment to kill the bacteria effectively.

Graphical abstract: Charge-reversal silver clusters for targeted bacterial killing
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Zwitterionic choline phosphate conjugated folate-poly (ethylene glycol): a general decoration of erythrocyte membrane-coated nanoparticles for enhanced tumor-targeting drug delivery

A general decoration of erythrocyte membrane-coated nanoparticles for enhanced tumor-targeting drug delivery based on the “CP–PC” interaction of MCP-PEG-FA and erythrocyte membranes.

Graphical abstract: Zwitterionic choline phosphate conjugated folate-poly (ethylene glycol): a general decoration of erythrocyte membrane-coated nanoparticles for enhanced tumor-targeting drug delivery
Paper

Photocontrolled chondrogenic differentiation and long-term tracking of mesenchymal stem cells in vivo by upconversion nanoparticles

The synthesis of a multifunctional UCNP nanoplatform and the photocontrolled chondrogenic differentiation and long-term tracking of MSCs in vitro and in vivo by UCNP nanoplatforms through NIR light.

Graphical abstract: Photocontrolled chondrogenic differentiation and long-term tracking of mesenchymal stem cells in vivo by upconversion nanoparticles
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Construction of a stereocomplex between poly(D-lactide) grafted hydroxyapatite and poly(L-lactide): toward a bioactive composite scaffold with enhanced interfacial bonding

Hydroxyapatite (HAP) grafted with poly( D-lactide) (PDLA) was incorporated into poly(L-lactide) (PLLA) to construct a stereocomplex, thus improving the interfacial bonding between PLLA and HAP like a zip-lock structure in a scaffold.

Graphical abstract: Construction of a stereocomplex between poly(d-lactide) grafted hydroxyapatite and poly(l-lactide): toward a bioactive composite scaffold with enhanced interfacial bonding
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Functionalization of filled radioactive multi-walled carbon nanocapsules by arylation reaction for in vivo delivery of radio-therapy

In vivo studies of 153SmCl3@MWCNTs, functionalized with an optimized procedure, show their high accumulation mainly in lung, liver and spleen, prompting the suitability to passively target various tumor types in future efficacy studies in animals.

Graphical abstract: Functionalization of filled radioactive multi-walled carbon nanocapsules by arylation reaction for in vivo delivery of radio-therapy
From the themed collection: Journal of Materials Chemistry B HOT Papers
Open Access Paper

Evaluating the impact of systematic hydrophobic modification of model drugs on the control, stability and loading of lipid-based nanoparticles

An investigation of how the LogP value of an active controls the formation of lipid-based nanoparticles. Hydrophobically-modified drug analogues were formulated to give nanoparticles with much higher drug loadings than conventional lipid nanocarriers.

Graphical abstract: Evaluating the impact of systematic hydrophobic modification of model drugs on the control, stability and loading of lipid-based nanoparticles
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Synergic influences of network topologies and associative interactions on the microstructures and bulk performances of hydrogels

We develop hydrogels with constant composition yet different network topologies, which result in hydrogen-bond associations of different strengths and densities, as well as distinct microstructures and properties of the gels.

Graphical abstract: Synergic influences of network topologies and associative interactions on the microstructures and bulk performances of hydrogels
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Microenvironment-responsive multifunctional hydrogels with spatiotemporal sequential release of tailored recombinant human collagen type III for the rapid repair of infected chronic diabetic wounds

A brand-new tailored hCol III-based microenvironment-responsive hydrogel could effectively accelerate the repair and regeneration of chronic diabetic wounds by a programmed controlled release of therapeutic substance approach.

Graphical abstract: Microenvironment-responsive multifunctional hydrogels with spatiotemporal sequential release of tailored recombinant human collagen type III for the rapid repair of infected chronic diabetic wounds
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

In situ construction of a nano-structured akermanite coating for promoting bone formation and osseointegration of Ti–6Al–4V implants in a rabbit osteoporosis model

In situ construction of nano-structured akermanite (nAK) coatings on Ti–6Al–4V implants and their promotion for osteogenesis and osseointegration in osteoporosis.

Graphical abstract: In situ construction of a nano-structured akermanite coating for promoting bone formation and osseointegration of Ti–6Al–4V implants in a rabbit osteoporosis model
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

A natural polysaccharide-based antibacterial functionalization strategy for liquid and air filtration membranes

A natural polysaccharide-based strategy was developed for the facile and universal antimicrobial functionalization of filtration materials.

Graphical abstract: A natural polysaccharide-based antibacterial functionalization strategy for liquid and air filtration membranes
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Facile synthesis of near-infrared bodipy by donor engineering for in vivo tumor targeted dual-modal imaging

The impact of donor strength on Bodipys’ optical properties and its applications for tumor near-infrared fluorescence imaging and photoacoustic tomography.

Graphical abstract: Facile synthesis of near-infrared bodipy by donor engineering for in vivo tumor targeted dual-modal imaging
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

131I-Labeled gold nanoframeworks for radiotherapy-combined second near-infrared photothermal therapy of cancer

Radionuclide 131I-labeled gold nanoframeworks (131I-AuNFs) are developed for radiotherapy-combined second near-infrared photothermal therapy of breast cancer.

Graphical abstract: 131I-Labeled gold nanoframeworks for radiotherapy-combined second near-infrared photothermal therapy of cancer
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Defective Ag–In–S/ZnS quantum dots: an oxygen-derived free radical scavenger for mitigating macrophage inflammation

The as-prepared defective AIS/ZnS QDs have favorable oxygen-derived free radical scavenging abilities in vitro and exhibit benign anti-inflammatory activities in the model of lipopolysaccharide (LPS)-induced inflammation in macrophages.

Graphical abstract: Defective Ag–In–S/ZnS quantum dots: an oxygen-derived free radical scavenger for mitigating macrophage inflammation
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Photothermally responsive Pickering emulsions stabilised by polydopamine nanobowls

In this study, polydopamine mesoporous nanobowls stabilise photothermally responsive oil-in water Pickering emulsions. Prepared emulsions show excellent photothermal efficiency under near-infrared (NIR) illumination, offering potential in NIR triggered drug release.

Graphical abstract: Photothermally responsive Pickering emulsions stabilised by polydopamine nanobowls
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

A multifunctional targeted nanoprobe with high NIR-II PAI/MRI performance for precise theranostics of orthotopic early-stage hepatocellular carcinoma

A novel GPC-3-targeted multifunctional nanoprobe for precise theranostics of orthotopic early-stage hepatocellular carcinoma was developed via dual-modal photoacoustic/magnetic resonance imaging and imaging guided non-invasive photothermal therapy.

Graphical abstract: A multifunctional targeted nanoprobe with high NIR-II PAI/MRI performance for precise theranostics of orthotopic early-stage hepatocellular carcinoma
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Selective and stoichiometric incorporation of ATP by self-assembling amyloid fibrils

The merger of insulin's amyloidogenic segment and an octalysine stretch produces a chimeric peptide with the ability to bind and incorporate stoichiometric amounts of ATP upon co-aggregation and formation of amyloid fibrils.

Graphical abstract: Selective and stoichiometric incorporation of ATP by self-assembling amyloid fibrils
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Grafting of Gd-DTPA onto MOF-808 to enhance MRI performance for guiding photothermal therapy

A MRI guided photothermal therapy agent Gd-DTPA-MOF-808@PANI was developed through grafting T1-weight contrast agent Gd-DTPA molecule within the porous channel of MOF-808 and modified with polyaniline (PANI).

Graphical abstract: Grafting of Gd-DTPA onto MOF-808 to enhance MRI performance for guiding photothermal therapy
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Bioinspired NO release coating enhances endothelial cells and inhibits smooth muscle cells

Introducing nitric oxide (NO) to traditional drug-eluting stents alleviates incomplete endothelialization and further inhibit the stenosis caused by the proliferation of smooth muscle cells.

Graphical abstract: Bioinspired NO release coating enhances endothelial cells and inhibits smooth muscle cells
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

A non-peptide probe for detecting chymotrypsin activity based on protection–deprotection strategy in living systems

A non-peptide probe for detecting chymotrypsin activity based on a protection–deprotection strategy in living systems.

Graphical abstract: A non-peptide probe for detecting chymotrypsin activity based on protection–deprotection strategy in living systems
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Highly sensitive non-enzymatic electrochemical glucose sensor surpassing water oxidation interference

An electrochemical non-enzymatic sensor based on a NiVP/Pi material was developed for the selective and sensitive determination of glucose.

Graphical abstract: Highly sensitive non-enzymatic electrochemical glucose sensor surpassing water oxidation interference
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

A photo and tumor microenvironment activated nano-enzyme with enhanced ROS generation and hypoxia relief for efficient cancer therapy

Reactive oxygen species (ROS) mediated tumor therapy strategies have exhibited great prospects and attracted increasing attention, among which photodynamic therapy (PDT) has been well-established.

Graphical abstract: A photo and tumor microenvironment activated nano-enzyme with enhanced ROS generation and hypoxia relief for efficient cancer therapy
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

A highly selective ratiometric molecular probe for imaging peroxynitrite during drug-induced acute liver injury

Visualizing ONOO fluctuations in the complex drug-induced acute liver injury process using a ratiometric fluorescent probe developed by using a molecular hybridization strategy with high selectivity and sensitivity.

Graphical abstract: A highly selective ratiometric molecular probe for imaging peroxynitrite during drug-induced acute liver injury
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

A carbonized wormwood modified photothermal microneedle patch for the repair of damaged skeletal muscles

In this study, we aimed to achieve an efficient repair of damaged skeletal muscles using polyvinyl alcohol (PVA) soluble microneedle patches (MNP) loaded with carbonized wormwood and prostaglandin E2 (inflammatory factors).

Graphical abstract: A carbonized wormwood modified photothermal microneedle patch for the repair of damaged skeletal muscles
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

The role of micro-vibration parameters in inflammatory responses of macrophages cultured on biphasic calcium phosphate ceramics and the resultant influence on osteogenic differentiation of mesenchymal stem cells

Micro-vibration stimulation (MVs) plays a critical role in regulating the inflammatory responses of macrophages to BCP ceramics and further inducing the osteogenic differentiation of BMMSCs in a paracrine manner.

Graphical abstract: The role of micro-vibration parameters in inflammatory responses of macrophages cultured on biphasic calcium phosphate ceramics and the resultant influence on osteogenic differentiation of mesenchymal stem cells
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

A multidimensional biosensor system to guide LUAD individualized treatment

We report a multidimensional biosensor system to guide adenocarcinoma individualized treatment by integrating 2D and 3D PDC models and novel cellular impedance biosensors. The strategy may contribute to individualized treatment and drug development.

Graphical abstract: A multidimensional biosensor system to guide LUAD individualized treatment
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Poly(vinyl alcohol-co-itaconic acid) hydrogels grafted with several designed peptides for human pluripotent stem cell culture and differentiation into cardiomyocytes

Human pluripotent stem cells can be successfully cultured on hydrogels grafted with laminin-β4 peptide having appropriate ζ potential, which have a joint segment, dual chain motif, and cationic amino acid insertion.

Graphical abstract: Poly(vinyl alcohol-co-itaconic acid) hydrogels grafted with several designed peptides for human pluripotent stem cell culture and differentiation into cardiomyocytes
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Mesoporous polydopamine-coated hydroxyapatite nano-composites for ROS-triggered nitric oxide-enhanced photothermal therapy of osteosarcoma

A multifunctional therapeutic nanoplatform for ROS-triggered NO-enhanced photothermal therapy of osteosarcoma.

Graphical abstract: Mesoporous polydopamine-coated hydroxyapatite nano-composites for ROS-triggered nitric oxide-enhanced photothermal therapy of osteosarcoma
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Vascular transplantation with dual-biofunctional ePTFE vascular grafts in a porcine model

The in vivo porcine carotid artery replacement studies showed that bivalirudin (BVLD) and REDV co-modified ePTFE vascular grafts could maintain ideal patency and realize endothelialization on the luminal surface at 12 weeks after implantation.

Graphical abstract: Vascular transplantation with dual-biofunctional ePTFE vascular grafts in a porcine model
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Delivery of a system xc inhibitor by a redox-responsive levodopa prodrug nanoassembly for combination ferrotherapy

A ferroptosis nano-prodrug (SSZ–Fe2+@DSSD) that can generate intercellular ROS and inhibit the system xc-GSH-GPX4 pathway to enhance the cancer ferrotherapy.

Graphical abstract: Delivery of a system xc− inhibitor by a redox-responsive levodopa prodrug nanoassembly for combination ferrotherapy
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Molecule-specific vibration-based chiral differentiation of Raman spectra using cysteine modified gold nanoparticles: the cases of tyrosine and phenylalanine

The chirality of amino acids plays a key role in many biochemical processes, with the development of spectroscopic analysis methods for the chiral differentiation of amino acids being significant.

Graphical abstract: Molecule-specific vibration-based chiral differentiation of Raman spectra using cysteine modified gold nanoparticles: the cases of tyrosine and phenylalanine
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Tannic acid-inspired, self-healing, and dual stimuli responsive dynamic hydrogel with potent antibacterial and anti-oxidative properties

Tannic acid cross-linked dynamic hydrogels hybridized with tannic acid reduced silver nanoparticles shows multi-functional properties including dual stimuli responsive drug release, anti-bacterial and anti-reactive oxygen species abilities.

Graphical abstract: Tannic acid-inspired, self-healing, and dual stimuli responsive dynamic hydrogel with potent antibacterial and anti-oxidative properties
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Graphene-coated copper-doped ZnO quantum dots for sensitive photoelectrochemical bioanalysis of thrombin triggered by DNA nanoflowers

This work reports a photoelectrochemical biosensing platform for thrombin using graphene oxide-coated copper-doped zinc oxide quantum dots as the photoactive materials and glucose oxidase-encapsulated DNA nanoflowers for signal amplification.

Graphical abstract: Graphene-coated copper-doped ZnO quantum dots for sensitive photoelectrochemical bioanalysis of thrombin triggered by DNA nanoflowers
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Urate oxidase loaded in PCN-222(Fe) with peroxidase-like activity for colorimetric detection of uric acid

A simple uric acid detection method is successfully developed through the integration of urate oxidase (UOx) and PCN-222(Fe) with peroxidase-like activity.

Graphical abstract: Urate oxidase loaded in PCN-222(Fe) with peroxidase-like activity for colorimetric detection of uric acid
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Facile synthesis of biocompatible magnetic titania nanorods for T1-magnetic resonance imaging and enhanced phototherapy of cancers

The designed Pluronic® F-127 coated Fe–TiO2 NCs promote the growth of intestine organoids, demonstrate remarkable T1 contrast in MRI and significant photodynamic therapy of breast cancer at very low UV power (2.5 mW cm−2).

Graphical abstract: Facile synthesis of biocompatible magnetic titania nanorods for T1-magnetic resonance imaging and enhanced phototherapy of cancers
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Bioorthogonal chemistry in metal clusters: a general strategy for the construction of multifunctional probes for bioimaging in living cells and in vivo

Bioorthogonal chemistry in metal clusters: a new strategy for the preparation of modular multifunctional probes based on the bioorthogonal reaction system is presented.

Graphical abstract: Bioorthogonal chemistry in metal clusters: a general strategy for the construction of multifunctional probes for bioimaging in living cells and in vivo
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Effects of bioactive strontium-substituted hydroxyapatite on osseointegration of polyethylene terephthalate artificial ligaments

The insufficient bioactivity of PET artificial ligaments severely weakens the ligament-bone healing in ACL reconstruction, while osteogenic modification is a prevailing method to enhance osseointegration of PET artificial ligaments.

Graphical abstract: Effects of bioactive strontium-substituted hydroxyapatite on osseointegration of polyethylene terephthalate artificial ligaments
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Substance P containing peptide gene delivery vectors for specifically transfecting glioma cells mediated by a neurokinin-1 receptor

Gene therapy provides a promising treatment for glioblastoma multiforme, which mainly depends on two key aspects, crossing the blood brain barrier (BBB) effectively and transfecting target cells selectively.

Graphical abstract: Substance P containing peptide gene delivery vectors for specifically transfecting glioma cells mediated by a neurokinin-1 receptor
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Fabricating a wettable microwells array onto a nitrogen plasma-treated ITO substrate: high-throughput fluorimetric platform for selective sensing of ammonia in blood using polymer-stabilized NH2-MIL-125

Fluorescent NH2-MIL-125 encapsulated in a polymer was coated into wettable microwells array for the sensing of NH3, and demonstrated a target enrichment capability and enhanced responses.

Graphical abstract: Fabricating a wettable microwells array onto a nitrogen plasma-treated ITO substrate: high-throughput fluorimetric platform for selective sensing of ammonia in blood using polymer-stabilized NH2-MIL-125
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

A novel theranostic nanoplatform for imaging-guided chemo-photothermal therapy in oral squamous cell carcinoma

We constructed the PDA-modified HATb nanoparticle encapsulating the anticancer drug DOX (HATb-PDA-DOX), which achieved pH/NIR triggered drug release and imaging-guided synergistic chemo-photothermal tumor therapy.

Graphical abstract: A novel theranostic nanoplatform for imaging-guided chemo-photothermal therapy in oral squamous cell carcinoma
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

A zwitterionic polypeptide nanocomposite with unique NIR-I/II photoacoustic imaging for NIR-I/II cancer photothermal therapy

We put forward an innovative strategy to construct a zwitterionic polypeptide nanocomposite which mediated unique NIR-I/II PAI and NIR-II PTT to completely eradicate MCF-7 tumors in vivo. This study will accelerate the polypeptide nanomedicine for clinical transition.

Graphical abstract: A zwitterionic polypeptide nanocomposite with unique NIR-I/II photoacoustic imaging for NIR-I/II cancer photothermal therapy
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Hydrophilic and anti-adhesive modification of porous polymer microneedles for rapid dermal interstitial fluid extraction

A facile and mild polydopamine (PDA) and poly(ethylene glycol) (PEG) coating strategy is reported for hydrophilic and anti-adhesive modification of porous polymer MNs from a phase inversion method.

Graphical abstract: Hydrophilic and anti-adhesive modification of porous polymer microneedles for rapid dermal interstitial fluid extraction
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Antimicrobial and degradable triazolinedione (TAD) crosslinked polypeptide hydrogels

Controlling molecular weight, crosslink density and chirality in covalent polypeptide hydrogels allows the independent tuning of rheological, water uptake, degradation and antimicrobial properties.

Graphical abstract: Antimicrobial and degradable triazolinedione (TAD) crosslinked polypeptide hydrogels
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

An electrochemical biosensing platform for progesterone hormone detection using magnetic graphene oxide

A facile and label-free electrochemical approach based on magnetic graphene oxide nanomaterials with a large surface to volume ratio and less susceptible to aggregation proved promising in developing highly sensitive and selective sensing of progesterone.

Graphical abstract: An electrochemical biosensing platform for progesterone hormone detection using magnetic graphene oxide
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Oxygen-producing proenzyme hydrogels for photodynamic-mediated metastasis-inhibiting combinational therapy

An oxygen-producing proenzyme hydrogel with near-infrared photoactivatable enzymatic activity was developed for photodynamic therapy enabled metastasis-inhibiting combinational therapy of breast cancer.

Graphical abstract: Oxygen-producing proenzyme hydrogels for photodynamic-mediated metastasis-inhibiting combinational therapy
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Impact of the chain length on the biodistribution profiles of PEGylated iron oxide nanoparticles: a multimodal imaging study

Bimodal sub-5 nm superparamagnetic iron oxide nanoparticles (SPIO-5) coated with polyethylene glycol of different chain lengths (i.e. PEG-800, -2000 and -5000) have been prepared and characterized.

Graphical abstract: Impact of the chain length on the biodistribution profiles of PEGylated iron oxide nanoparticles: a multimodal imaging study
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Carbonized zein nanosheets with intrinsic enzyme-mimicking activities and high photothermal conversion efficiency for synergistic cancer therapy

A facile and economic method to fabricate N-rich carbon nanozyme is presented by using zein as a precursor. This material possesses intrinsic oxidase- and peroxidase-like activities, and can be applied as a robust agent for cancer treatment.

Graphical abstract: Carbonized zein nanosheets with intrinsic enzyme-mimicking activities and high photothermal conversion efficiency for synergistic cancer therapy
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Cascade catalytic nanoplatform constructed by laterally-functionalized pillar[5]arenes for antibacterial chemodynamic therapy

A cascade catalytic nanoplatform was established for effective chemodynamic antibacterial therapy.

Graphical abstract: Cascade catalytic nanoplatform constructed by laterally-functionalized pillar[5]arenes for antibacterial chemodynamic therapy
From the themed collection: Journal of Materials Chemistry B HOT Papers
109 items - Showing page 1 of 2

About this collection

This on-going web collection features all the articles published in Journal of Materials Chemistry B in 2021 marked as HOT (selected by our Editors as especially significant based on reviewers’ recommendations and their own appraisal). Congratulations to all the authors whose articles are featured!

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