Themed collection ISACS18: Challenges in Organic Materials and Supramolecular Chemistry
Anion–π catalysis: bicyclic products with four contiguous stereogenic centers from otherwise elusive diastereospecific domino reactions on π-acidic surfaces
Delocalized over aromatic planes, anion–π interactions emerge as best to stabilize long-distance charge displacements in domino reactions of highest sophistication.
Tuning the polarity of charge carriers using electron deficient thiophenes
Highly electron deficient thiophene building blocks are used to induce LUMO-conducting behaviour from the parent HOMO-conducting pentathiophene in single-molecule junctions.
Template-directed synthesis of linear porphyrin oligomers: classical, Vernier and mutual Vernier
We demonstrate a variety of template-directed strategies for preparing linear monodisperse butadiyne-linked porphyrin oligomers by Glaser–Hay coupling, based on the coordination of pyridine-substituted nickel(II) porphyrins to zinc(II) porphyrins.
Pentafluorobenzene end-group as a versatile handle for para fluoro “click” functionalization of polythiophenes
Inclusion of a perfluorophenyl endgroup enables the ready functionalization of water soluble polythiophenes under mild conditions.
Aqueous interfacial gels assembled from small molecule supramolecular polymers
The successful self-assembly of a stimuli-responsive aqueous supramolecular hyperbranched polymer from small molecules and the macrocyclic host cucurbituril (CB) is reported. This self-healing supramolecular network can act as a soft matter barrier at liquid–liquid interfaces.
Nanorings with copper(II) and zinc(II) centers: forcing copper porphyrins to bind axial ligands in heterometallated oligomers
The stability of copper/zinc heterometallated porphyrin complex oligomers provides information on the strength of the copper porphyrin pyridine interaction. Heterometallated nanorings were prepared by template-directed synthesis.
Exploring template-bound dinuclear copper porphyrin nanorings by EPR spectroscopy
Electron paramagnetic resonance spectroscopy reveals the molecular geometry and metal–ligand interactions in template-bound ten-membered bis-copper porphyrin nanorings.
A protein–dye hybrid system as a narrow range tunable intracellular pH sensor
A two-component hybrid system consisting of organic dye nanoparticles (ash) and a protein (blue) at different ratios allows for the design of narrow range tunable nanoprobes for sensing and imaging of pH variations in live cells through ratiometric signalling.
Conformations of cyclopentasilane stereoisomers control molecular junction conductance
Here we examine the impact of ring conformation on the charge transport characteristics of cyclic pentasilane structures bound to gold electrodes in single molecule junctions.
Controlling amphiphilic copolymer self-assembly morphologies based on macrocycle/anion recognition and nucleotide-induced payload release
We create polymeric self-assembly morphologies by exploiting the anion binding features of the so-called ‘Texas-sized’ molecular box.
Bio-inspired supramolecular materials by orthogonal self-assembly of hydrogelators and phospholipids
We report how to identify orthogonal self-assembly and describe guidelines to achieve self-sorting in self-assembled mixed systems.
Tandem reactions in self-sorted catalytic molecular hydrogels
We report the orthogonal assembly of two structurally dissimilar catalytic hydrogelators with mutually incompatible functional groups able to retain their individual catalytic activity and thus catalyse tandem reactions in one pot.
Fluorescent transmembrane anion transporters: shedding light on anionophoric activity in cells
A series of fluorescent anion transporters have been synthesised and their anion transport properties and interactions with cancer cell lines studied.
The third orthogonal dynamic covalent bond
The existence of three fully orthogonal dynamic covalent bonds is demonstrated in solution and in functional surface architectures.
Supercoiled fibres of self-sorted donor–acceptor stacks: a turn-off/turn-on platform for sensing volatile aromatic compounds
Supercoiled fibres of self-sorted donor–acceptor assemblies that allow the sensing of nitroaromatics and aromatic amines using a “turn-off/turn-on” mechanism are reported.
Post-synthetic modification of a macrocyclic receptor via regioselective imidazolium ring-opening
Shown in graphic form is the use of mild basic conditions to effect the post-synthetic, ring-opening based modification of a tetraimidazolium macrocycle known as the “Texas box”. This ring opening modulates the intrinsic binding characteristics of the system.
Real time monitoring of aminothiol level in blood using a near-infrared dye assisted deep tissue fluorescence and photoacoustic bimodal imaging
Real time monitoring of blood aminothiol level by a near-IR dye assisted fluorescence–photoacoustic bimodal imaging is reported.
Non-cyclic formylated dipyrromethanes as phosphate anion receptors
Tetrakis- and hexakis(1H-pyrrole-2-carbaldehyde) anion receptors are described that undergo conformational reorganization in order to accommodate the dihydrogenphosphate and pyrophosphate anions.
Solvent-dependent conductance decay constants in single cluster junctions
We study single cluster electrical transport in a series of metal chalcogenide molecular clusters using scanning tunneling microscope-based break-junction measurements.
QSAR analysis of substituent effects on tambjamine anion transporters
A QSAR analysis of the transmembrane anion transport activity of 43 synthetic tambjamine analogs allowed rationalization of this activity according to their lipophilicity and structural parameters.
Influence of the heteroatom on the optoelectronic properties and transistor performance of soluble thiophene-, selenophene- and tellurophene–vinylene copolymers
We report the first soluble poly(3-dodecyl tellurophenylenevinylene) and compare its properties to the analogous thiophene and selenophene containing polymers.
The role of capsule stiffness on cellular processing
A systematic and quantitative study on the role of capsule stiffness in cellular processing was performed using hyaluronic acid capsules with tunable stiffness constructed via continuous assembly of polymers.
A mechanically interlocked molecular system programmed for the delivery of an anticancer drug
The development of mechanically interlocked molecular systems programmed to operate autonomously in biological environments is an emerging field of research with potential medicinal applications.
About this collection
We are delighted to present this web collection which contains selected contributions from the ISACS18: Challenges in Organic Materials and Supramolecular Chemistry meeting held in Bangalore, India in November 2015. Delegates from countries around the world gathered to hear from leading researchers in this exciting field and now we have the opportunity to share with you exciting new research from a number of our plenary speakers and scientific committee members. We hope you enjoy the collection.