Themed collection Chemistry in the battle against infections
A comprehensive review on antimicrobial face masks: an emerging weapon in fighting pandemics
Schematic representation of antimicrobial face masks with details of various antimicrobial agents and its preparation route.
Antibiofilm peptides: overcoming biofilm-related treatment failure
Host defence peptides (HDPs) can overcome biofilm-specific resistance and immune evasion mechanisms that render antibiotics ineffective. Infection models mimicking the resilience of biofilms are crucial for the development of these therapeutics.
Green synthesis of silver nanoparticles using plant extracts and their antimicrobial activities: a review of recent literature
Herein, we have reviewed new findings in the research domain of the green synthesis of silver nanoparticles using different plant extracts and their potential applications as antimicrobial agents covering the literature since 2015.
Natural products' role against COVID-19
Natural products can play an important role in COVID-19 chemotherapy development.
CuAAC-ensembled 1,2,3-triazole-linked isosteres as pharmacophores in drug discovery: review
The review lays emphasis on the significance of 1,2,3-triazoles synthesized via CuAAC reaction having potential to act as anti-microbial, anti-cancer, anti-viral, anti-inflammatory, anti-tuberculosis, anti-diabetic, and anti-Alzheimer drugs.
Novel diagnostics for point-of-care bacterial detection and identification
The WHO global action plan on antimicrobial resistance outlines the need for new diagnostic tools. Point-of-care testing for bacterial infections would enable clinically meaningful interventions using methods that are rapid, low-cost, easy-to-operate, and portable.
A review on the biosynthesis of metal and metal salt nanoparticles by microbes
This review paper is a comprehensive outline of biosynthesis of metal nanoparticles by microbes including their mechanistic aspects, large-scale production approaches, mechanism of action, advantages and limitations of bio-mediated approach.
Green synthesis of silver nanoparticles: biomolecule-nanoparticle organizations targeting antimicrobial activity
In this review, we discuss the recent advances in green synthesis of silver nanoparticles, their application as antimicrobial agents and mechanism of antimicrobial mode of action.
Challenges in application of Raman spectroscopy to biology and materials
This paper reviews various facets of Raman spectroscopy. This encompasses biomolecule fingerprinting and conformational analysis, discrimination of healthy vs. diseased states, depth-specific information of materials and 3D Raman imaging.
Selected organophosphorus compounds with biological activity. Applications in medicine
The purpose of this article is to provide an overview of the latest applications of organophosphorus compounds (OPs) that exhibit biological activity.
Anti-bacterial surfaces: natural agents, mechanisms of action, and plasma surface modification
This article reviews antibacterial surface strategies based on reactive plasma chemistry, focusing on how plasma-assisted processing of natural antimicrobial agents can produce antifouling and antibacterial materials for biomedical devices.
Synthetic methodologies of achiral diarylmethanols, diaryl and triarylmethanes (TRAMs) and medicinal properties of diaryl and triarylmethanes-an overview
This review covers the synthesis of achiral diarylmethanols, diaryl and triarylmethanes and the bioactivities of diaryl and triarylmethanes during 1995 to 2013.
Superhydrophobic surfaces for the reduction of bacterial adhesion
Superhydrophobic surfaces, inspired by the Lotus leaf, are an emerging solution to reduce bacterial adhesion on material surfaces.
Multi-functional fluorescent carbon dots with antibacterial and gene delivery properties
Dual-functionality carbon dots with both anti-microbial and gene transfection abilities were developed and their properties elaborated in this paper.
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
The Aquilegia pubiflora (Himalayan columbine) mediated synthesis of nanoceria for diverse biomedical applications
Graphical illustration of eco-friendly, facile, one-pot, green synthesis of nanoceria for multiple biomedical applications.
Anti-HIV drug repurposing against SARS-CoV-2
A novel severe acute respiratory syndrome human coronavirus (SARS HCoV) was identified from respiratory illness patients (named SARS-CoV-2 by ICTV) in December 2019 and has recently emerged as a serious threat to world public health.
Biogenesis of ZnO nanoparticles using Pandanus odorifer leaf extract: anticancer and antimicrobial activities
The continuously increasing incidence rates of cancer and infectious diseases are open threats to the sustainable survival of animals and humans.
Graphene oxide decorated with zinc oxide nanoflower, silver and titanium dioxide nanoparticles: fabrication, characterization, DNA interaction, and antibacterial activity
The fabrication, characterization, and antibacterial activity of novel nanocomposites based on graphene oxide (GO) nanosheets decorated with silver, titanium dioxide nanoparticles, and zinc oxide nanoflowers were examined.
Alginate based antimicrobial hydrogels formed by integrating Diels–Alder “click chemistry” and the thiol–ene reaction
In recent years medical devices manufacturers have been looking for antimicrobial coatings which are biocompatible and non-toxic for a wide range of medical devices.
A label-free electrochemical platform for the highly sensitive detection of hepatitis B virus DNA using graphene quantum dots
Based on the interaction between single-stranded probe DNA and graphene quantum dots (GQDs), we have designed a simple but smart electrochemical platform to detect HBV-DNA by using GQDs modified glassy carbon electrode coupled with probe DNA.
Development of noncytotoxic silver–chitosan nanocomposites for efficient control of biofilm forming microbes
We describe the synthetic pathway to produce efficient bactericidal, fungicidal and non-cytotoxic chitosan–ascorbic acid–silver composites as solid films.
ATR-FTIR spectroscopy coupled with multivariate analysis techniques for the identification of DENV-3 in different concentrations in blood and serum: a new approach
In most cases of virus infections the viral load is directly related to the intensity of the disease.
Delving into Zika virus structural dynamics – a closer look at NS3 helicase loop flexibility and its role in drug discovery
This study demonstrates the structural alterations in the P-loop of ZIKV helicase subsequent to binding of potent inhibitor, NITD008.
Surface characteristics influencing bacterial adhesion to polymeric substrates
Effective surface area on rough substrates for bacterial adhesion is examined by analyzing the solid area fraction of surfaces, where the bacterial medium is in contact with the solid surface.
ZnO/Ag/Mn2O3 nanocomposite for visible light-induced industrial textile effluent degradation, uric acid and ascorbic acid sensing and antimicrobial activity
Ternary ZnO/Ag/Mn2O3 nanocomposite as photocatalyst, sensing and antimicrobial material.
Automated nucleic acid extraction from whole blood, B. subtilis, E. coli, and Rift Valley fever virus on a centrifugal microfluidic LabDisk
We present total nucleic acid extraction from whole blood, Gram-positive Bacillus subtilis, Gram-negative Escherichia coli, and Rift Valley fever RNA virus on a low-cost, centrifugal microfluidic cartridge processed in a portable processing device.
Osteoblastic cell responses and antibacterial efficacy of Cu/Zn co-substituted hydroxyapatite coatings on pure titanium using electrodeposition method
Effective physiological bone integration and absence of bacterial infection are essential for a successful orthopaedic or dental implant.
Understanding the pathway of antibacterial activity of copper oxide nanoparticles
This work investigates the role of oxidation state in the antibacterial activity of copper oxide nanoparticles (NPs).
Size-controlled silver nanoparticles synthesized over the range 5–100 nm using the same protocol and their antibacterial efficacy
Size-specific antibacterial activity of 5–100 nm silver nanoparticles synthesized using a novel co-reduction approach.
nanoparticle-coated surfaces inhibit bacterial biofilm formation and increase antibiotic susceptibility
Antibiofilm activity of ZnO NP coatings. CLSM images of E. coli and S. aureus following biofilm formation over the course of ten consecutive days on uncoated and ZnO NP-coated glass surfaces
About this collectionWe are very pleased to present our 10th Anniversary collection on Chemistry in the battle against infections!
Looking back over the last 10 years, we would like to showcase some of the very best articles that have been published in RSC Advances. Many of these papers have been cited hundreds of times, providing valuable advances for further research, and some continue to be among the journal’s most downloaded articles as of today.
We hope you enjoy our 10th Anniversary collection on Chemistry in the battle against infections!