Themed collection Chemistry in the battle against infections

Schematic representation of antimicrobial face masks with details of various antimicrobial agents and its preparation route.

Host defence peptides (HDPs) can overcome biofilm-specific resistance and immune evasion mechanisms that render antibiotics ineffective. Infection models mimicking the resilience of biofilms are crucial for the development of these therapeutics.

Herein, we have reviewed new findings in the research domain of the green synthesis of silver nanoparticles using different plant extracts and their potential applications as antimicrobial agents covering the literature since 2015.

Natural products can play an important role in COVID-19 chemotherapy development.

The review lays emphasis on the significance of 1,2,3-triazoles synthesized via CuAAC reaction having potential to act as anti-microbial, anti-cancer, anti-viral, anti-inflammatory, anti-tuberculosis, anti-diabetic, and anti-Alzheimer drugs.

The WHO global action plan on antimicrobial resistance outlines the need for new diagnostic tools. Point-of-care testing for bacterial infections would enable clinically meaningful interventions using methods that are rapid, low-cost, easy-to-operate, and portable.

This review paper is a comprehensive outline of biosynthesis of metal nanoparticles by microbes including their mechanistic aspects, large-scale production approaches, mechanism of action, advantages and limitations of bio-mediated approach.

In this review, we discuss the recent advances in green synthesis of silver nanoparticles, their application as antimicrobial agents and mechanism of antimicrobial mode of action.

This paper reviews various facets of Raman spectroscopy. This encompasses biomolecule fingerprinting and conformational analysis, discrimination of healthy vs. diseased states, depth-specific information of materials and 3D Raman imaging.

The purpose of this article is to provide an overview of the latest applications of organophosphorus compounds (OPs) that exhibit biological activity.

This article reviews antibacterial surface strategies based on reactive plasma chemistry, focusing on how plasma-assisted processing of natural antimicrobial agents can produce antifouling and antibacterial materials for biomedical devices.

This review covers the synthesis of achiral diarylmethanols, diaryl and triarylmethanes and the bioactivities of diaryl and triarylmethanes during 1995 to 2013.

Superhydrophobic surfaces, inspired by the Lotus leaf, are an emerging solution to reduce bacterial adhesion on material surfaces.

Dual-functionality carbon dots with both anti-microbial and gene transfection abilities were developed and their properties elaborated in this paper.

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical illustration of eco-friendly, facile, one-pot, green synthesis of nanoceria for multiple biomedical applications.

A novel severe acute respiratory syndrome human coronavirus (SARS HCoV) was identified from respiratory illness patients (named SARS-CoV-2 by ICTV) in December 2019 and has recently emerged as a serious threat to world public health.

The continuously increasing incidence rates of cancer and infectious diseases are open threats to the sustainable survival of animals and humans.

The fabrication, characterization, and antibacterial activity of novel nanocomposites based on graphene oxide (GO) nanosheets decorated with silver, titanium dioxide nanoparticles, and zinc oxide nanoflowers were examined.

In recent years medical devices manufacturers have been looking for antimicrobial coatings which are biocompatible and non-toxic for a wide range of medical devices.

Based on the interaction between single-stranded probe DNA and graphene quantum dots (GQDs), we have designed a simple but smart electrochemical platform to detect HBV-DNA by using GQDs modified glassy carbon electrode coupled with probe DNA.

We describe the synthetic pathway to produce efficient bactericidal, fungicidal and non-cytotoxic chitosan–ascorbic acid–silver composites as solid films.

In most cases of virus infections the viral load is directly related to the intensity of the disease.

This study demonstrates the structural alterations in the P-loop of ZIKV helicase subsequent to binding of potent inhibitor, NITD008.

Effective surface area on rough substrates for bacterial adhesion is examined by analyzing the solid area fraction of surfaces, where the bacterial medium is in contact with the solid surface.

Ternary ZnO/Ag/Mn₂O₃ nanocomposite as photocatalyst, sensing and antimicrobial material.

We present total nucleic acid extraction from whole blood, Gram-positive Bacillus subtilis, Gram-negative Escherichia coli, and Rift Valley fever RNA virus on a low-cost, centrifugal microfluidic cartridge processed in a portable processing device.

Effective physiological bone integration and absence of bacterial infection are essential for a successful orthopaedic or dental implant.

This work investigates the role of oxidation state in the antibacterial activity of copper oxide nanoparticles (NPs).

Size-specific antibacterial activity of 5–100 nm silver nanoparticles synthesized using a novel co-reduction approach.

Antibiofilm activity of ZnO NP coatings. CLSM images of E. coli and S. aureus following biofilm formation over the course of ten consecutive days on uncoated and ZnO NP-coated glass surfaces