Themed collection 2021 Focus and Perspective articles
Two decades of recent advances of Passerini reactions: synthetic and potential pharmaceutical applications
This perspective describes the applications of Passerini reactions in the last two decades from 2000 to 2021 in pharmaceutical applications and synthesis of peptides, natural products, macrocycles, dendrimers, and versatile types of heterocycles.
Application of site-identification by ligand competitive saturation in computer-aided drug design
The present article summarizes the various tools developed in the context of the SILCS methodology and their utility in computer-aided drug design (CADD) applications.
A review on hierarchical Bi2MoO6 nanostructures for photocatalysis applications
This overview provides comprehensive understanding and development trends of hierarchical Bi2MoO6 nanostructures as photocatalysts for efficient photocatalysis applications.
The versatile roles of neutral donor ligands in tuning catalyst performance for the ring-opening polymerization of cyclic esters
The use of neutral donor ligands is an effective strategy to modify catalyst structure and performance in the synthesis of sustainable polymers through the ring-opening polymerization (ROP) of cyclic esters.
Immobilization of molecule-based ionic liquids: a promising approach to improve elecrocatalyst performance towards the hydrogen evolution reaction
Ionic liquids (ILs) have received continuous attention owing to their unique chemical and physical properties and to their successful integration in several applications.
The journey of C–S bond formation from metal catalysis to electrocatalysis
This perspective describes the journey of C–S bond constructions starting from transition metal catalysis through oxidant catalysis, photocatalysis and very recently employed electrocatalysis by using various sulfur surrogates.
Pyrochlore oxides as visible light-responsive photocatalysts
This perspective describes the use of pyrochlore oxides in photocatalysis with focus on the strategies to enhance their activity.
Current trends and perspectives on emerging Fe-derived noble-metal-free oxygen electrocatalysts
This article discusses recent progress in the development of Fe-derived noble metal-free electrocatalysts, including the strategies used for design, synthesis, and assessment of their performance in alkaline conditions.
Synthesis of polysubstituted pyrroles via isocyanide-based multicomponent reactions as an efficient synthesis tool
The present review covers all synthetic methods based on isocyanide-based multicomponent reactions for the preparation of polysubstituted pyrroles as the parent cores of many essential drugs, biologically active compounds, and compounds with wide application in materials science.
Electrospinning nanofiber technology: a multifaceted paradigm in biomedical applications
This review focuses on the process of preparation of nanofibers via Es, the design and setup of the instrument, critical parameter optimization, preferable polymers, solvents, characterization techniques, and recent development and biomedical applications of nanofibers.
Multilayer polymeric nanocomposites for electromagnetic interference shielding: fabrication, mechanisms, and prospects
Fabrication of multilayer EMI shield opens a creative avenue for designing and constructing flexible nanocomposite films simultaneously featuring excellent EMI shielding performance, fascinating heat removal ability, and robust mechanical properties.
Organosulfur, organoselenium, and organotellurium ligands in the development of palladium, nickel, and copper-based catalytic systems for Heck coupling
Organosulfur, organoselenium, and organotellurium ligands in designing Pd, Ni, and Cu-based homogeneous, heterogeneous, and nanocatalytic systems for Heck coupling.
Biomedical applications of metal–organic framework (MOF)-based nano-enzymes
In the present review, the types and activities of nanometer-sized enzymes are summarized, with recent progress of nanometer-sized enzymes in the field of biomedical detection.
Interface engineering and integration of two-dimensional polymeric and inorganic materials for advanced hybrid structures
Recent progress and future directions in the creation of hybrid structures based on 2D polymers and inorganic 2D materials are discussed.
Azapyrene-based fluorophores: synthesis and photophysical properties
The latest methods for the preparation/functionalization of azapyrenes, and their photophysical/electrochemical properties and possible applications are overviewed.
Beyond conventional construction of the phthalimide core: a review
This review highlights (2010–2021) different strategies for the construction of the phthalimide core apart from traditional synthetic routes.
Reactions involving aryl methyl ketone and molecular iodine: a powerful tool in the one-pot synthesis of heterocycles
The preparation of heterocyclic compounds has attracted great attention in organic chemistry because of their extensive application in the field of bioactive molecules, materials science, and natural products.
Name reactions: strategies in the design of chemodosimeters for analyte detection
The design and synthesis of suitable chemodosimeters for the detection of toxic analytes has become challenging for new researchers nowadays in the molecular recognition field.
Naturally derived sugar-based ionic liquids: an emerging tool for sustainable organic synthesis and chiral recognition
In the past decade, the synthesis of sugar-based ionic liquids (SILs) from natural sugars has been described as a promising strategy.
Chalcogenides as photocatalysts
Chalcogenides and chalcogenide-based heterostructures as photocatalysts.
Conjugated polymers – a versatile platform for various photophysical, electrochemical and biomedical applications: a comprehensive review
Tuneable properties of conjugated polymers are attractive for use in multiple domains like optical, electronic and biological applications.
Graphene, an epoch-making material in RFID technology: a detailed overview
Many researchers claim that graphene, a specially studied carbon allotrope, has a single layer of atoms organized in a two-dimensional honeycomb lattice.
Transition metal-free C-3 functionalization of quinoxalin-2(1H)-ones: recent advances and sanguine future
A gradual shift from metal-catalyzed to metal-free methods is occurring, as the latter are more environmentally benign. This review discusses sustainable protocols for the construction of C–C, C–N, C–P, C–S, and C–O bonds via C–H functionalization of quinoxalin-2(1H)-ones.
Progress and perspectives of electrochemical insights for C–H and N–H sulfonylation
A comprehensive electrosulfonylation study has been carried out via cathodic and anodic approaches for the production of organosulfone and sulfonamide derivatives.
Metal–organic framework (MOF)-derived catalysts for chemoselective hydrogenation of nitroarenes
The MOFs derived catalysts conducted in the chemoselective hydrogenation of substituted nitroarenes, including pyrolysis and confined catalyst, are reviewed.
Application of organometallic catalysts for the synthesis of o-tolyl benzonitrile, a key starting material for sartans
This review describes methods for the synthesis of o-tolyl benzonitrile, such as Pd-, Ni-catalyzed Suzuki, Negishi and Kumada couplings reactions.
A review of low-temperature H2S gas sensors: fabrication and mechanism
Reduced detection temperature of hazardous gases such as H2S can lower power consumption and increase the long-term stability. The decreased operating temperature can be achieved via physical and chemical modification of the sensing layer.
Copper-catalyzed N-arylation of pyrroles: an overview
The copper-catalyzed N-arylation of pyrroles has attracted great attention in organic synthesis due to its wide applications in medicinal chemistry, natural products, etc. Here, we summarize the overall advances in the copper-catalyzed C–N cross-coupling of pyrroles with aryl halides.
Recent developments in synthesis of catechols by Dakin oxidation
In recent years, Dakin oxidation has evolved primarily around the conversion of ortho- and para-hydroxy benzaldehydes and acetophenones to dihydric phenols, which are found in nature and complex organic materials.
Revisiting applications of molecular iodine in organic synthesis
Molecular iodine contributes significantly to organic transformations in synthetic organic chemistry. It works effectively due to its mild Lewis acidic character, ability as an oxidizing agent, good moisture stability, and easy availability.
Silica–sulfuric acid and alumina–sulfuric acid: versatile supported Brønsted acid catalysts
–SO3H functionalized silica and alumina have emerged as efficient and eco-compatible heterogeneous solid acid catalysts for the construction of various important molecular skeletons.
Multi-stimuli-responsive hydrogels and their medical applications
This review highlights the medical applications of multi-stimuli-responsive hydrogels as self-healing hydrogels, antibacterial materials and drug-delivery systems.
Silver-catalysed C–H bond activation: a recent review
Transition metal catalysed C–H activations are efficient, simple, mild, cost-effective and stereoselective, and many of them are environmentally sustainable transformations.
Progress in the self-assembly of porphyrin derivatives on surfaces: STM reveals
The latest progress in the assembly of porphyrin derivatives on solid surfaces.
A review on recent advances in amino acid and peptide-based fluorescence and its potential applications
Fluorescence is widely used to detect functional groups and ions, and peptides are used in various fields due to their excellent biological activity.
Superhydrophobic, superamphiphobic and SLIPS materials as anti-corrosion and anti-biofouling barriers
Multifunctional interfacial materials with special wettability including superhydrophobic, superamphiphobic, and SLIPS exhibited promising potentials for corrosion and biofouling resistance.
Plasmonic carriers responsive to pulsed laser irradiation: a review of mechanisms, design, and applications
This review focuses on interactions which govern release from plasmonic carrier systems including liposomes, polymersomes, and nanodroplets under pulsed irradiation.
Electrochemical aptasensors for the detection of hepatocellular carcinoma-related biomarkers
Recent progress in electrochemical aptasensors for the detection of HCC-related biomarkers, including cancer cells, proteins, cell-derived exosomes, and nucleic acids, is reviewed.
Zwitterions: promising interfacial/doping materials for organic/perovskite solar cells
This review summarizes the recent progress in zwitterionic materials through the concepts of interfacial dipoles and passivating defects.
Boronic-acid-derived covalent organic frameworks: from synthesis to applications
Modular, well-defined, and robust hierarchical functional materials are targets of numerous synthesis endeavors.
Iridium-catalysed borylation of pyrene – a powerful route to novel optoelectronic materials
We summarized the Ir-catalysed borylation of PAHs, especially pyrene, and the optoelectronic materials generated by following this chemistry. The optoelectronic properties of pyrene derivatives have also been discussed.
Current understanding of nanoparticle toxicity mechanisms and interactions with biological systems
Nanotechnology is an emerging science involving the manipulation of matter on the nanometer scale.
α-C–H functionalization of tertiary amines catalyzed/promoted by molecular iodine/derivatives
A recent review on the α-C–H functionalization of tertiary amines using low-cost and benign I2 or its derivatives.
4-Chloro-3-formylcoumarin as a multifaceted building block for the development of various bio-active substituted and fused coumarin heterocycles: a brief review
This review presents the diverse synthesis of 3,4-substituted coumarins and 5-, 6- and 7-membered ring fused coumarins using 4-chloro-3-formylcoumarin as the precursor via classical reactions including metal-catalyzed and green reaction protocols.
Protein aggregation detection with fluorescent macromolecular and nanostructured probes: challenges and opportunities
Nanoprobes based on various nanomaterials, polymers or AIEgens are overcoming previous limitations for diagnosis and therapy of early-stage protein aggregation.
Recent progress on the synthesis of henna-based dibenzoxanthenes
Xanthenes are a class of natural and synthetic heterocyclic compounds that exhibit a broad spectrum of biological properties and synthetic applications.
Transition metal-catalyzed C–H functionalizations of indoles
This review summarises a wide range of transformations on the indole skeleton, including arylation, alkenylation, alkynylation, acylation, nitration, borylation, and amidation, using transition-metal catalyzed C–H functionalization as the key step.
MOF/COF-based materials using 3D printing technology: applications in water treatment, gas removal, biomedical, and electronic industries
We have considered the newest outcomes in the uses of 3D-printed COF- and MOF-based materials for diverse applications.
Recent advances in the transition metal catalyzed synthesis of quinoxalines: a review
This review summarizes the recent developments in the synthesis of a variety of substituted quinoxalines using transition metal catalysts.
Core-functionalized nanoaggregates: preparation via polymerization-induced self-assembly and their applications
Core-functionalized nanoaggregates can be prepared by a combination of polymerization-induced self-assembly (PISA) and post-polymerization modification.
Recent developments in the synthesis of polysubstituted pyridines via multicomponent reactions using nanocatalysts
This review describes the evolution and application of active metal-based and heterometallic NPs as efficient heterogeneous catalysts for the synthesis of pyridine derivatives by multicomponent reactions in the last decade (2010–2020).
Metal-doped carbon nitrides: synthesis, structure and applications
This perspective provides a comprehensive overview of the latest progress of M–CN, which would promote further development, such as for single-atom catalysis and nanozymatic reactions.
1,3-Dipolar cycloaddition of nitrones: synthesis of multisubstituted, diverse range of heterocyclic compounds
The 1,3-dipolar cycloaddition reaction of nitrone is one of the most important methods for the synthesis of different sizes of heterocycles which have enormous applications in natural products, biologically active molecules and pharmaceuticals.
Recent advances in [3+2] cycloaddition of allenes with 1,3-carbonyl ylides; Rh(II)-catalyzed access to bridged polyoxocarbocyles
This study summarizes the stereochemical outcomes of [3+2] cycloaddition of allene molecules with 1,3-dipolar carbonyl ylides derived from Rh(II) carbene-mediated diazo decomposition for the formation of highly diastereoselective poly oxacarbocycles.
Strategies for optimizing the luminescence and stability of copper iodide organic–inorganic hybrid structures
In this article, the structural characteristics and synthetic methods of copper iodide hybrid materials are introduced, and the strategies for optimizing the stability and luminescence properties of these compounds are reviewed.
Pyrene based materials as fluorescent probes in chemical and biological fields
Molecules that experience a change in their fluorescence emission due to the effect of fluorescence enhancement upon binding events, like chemical reactions or a change in their immediate environment, are regarded as fluorescent probes.
Progress in propylene homo- and copolymers using advanced transition metal catalyst systems
Recent progress on advanced transition metal catalysts for propylene polymerization and copolymerization are reviewed.
Current achievements in 3D bioprinting technology of chitosan and its hybrids
Chitosan and its hybrids, as an appropriate bioink in 3D printing technology, for the fabrication of engineered constructions.
Modern trends in “Green” primary energetic materials
The evergrowing demand for cleaner, high-performing energetic materials (EMs) has led to a quest for replacement of currently used toxic metal-based traditional energetic compounds such as lead azide and lead styphnate.
Recent quinone diazide based transformations via metal–carbene formation
Recent advancements in versatile synthetic transformations using quinone diazide based metal carbenes have been summarized.
Organozinc hydrazides and their derivatives: synthesis, structural diversity and applications
This review highlights the synthetic aspects, structural diversity and possible applications of organozinc hydrazides and their derivatives.
A review of the incorporation of QDs and imprinting technology in optical sensors – imprinting methods and sensing responses
This review aims to cover the simultaneous method of using molecularly imprinted technology and quantum dots (QDs) as well as its application in the field of optical sensors.
Recent advances in the adsorptive remediation of wastewater using two-dimensional transition metal carbides (MXenes): a review
MXenes, since their discovery in 2011, have garnered significant research attention for a variety of applications due to their exciting physico-chemical properties.
Functionalization of imidazo[1,2-a]pyridines via radical reactions
The recent advances in radical reactions for the direct functionalization of imidazo[1,2-a]pyridines are reviewed.
An overview of the reactions involving azomethine imines over half a decade
Azomethine imines constitute a versatile class of 1,3-dipoles which was used extensively for biologically relevant N-heterocycle synthesis – a five-year recap.
Fight against COVID-19 pandemic with the help of carbon-based nanomaterials
We have considered the newest momentous outcomes in carbon-based nanomaterials for utility in controlling and fighting the SARS-CoV-2 virus.
Chromo-fluorogenic sensing using vitamin B6 cofactors and their derivatives: a review
A comprehensive review of chromo-fluorogenic sensors developed using vitamin B6 cofactors as the analyte recognition unit.
Metal–organic frameworks/biopolymer nanocomposites: from fundamentals toward recent applications in modern technology
Bio–nanocomposite compounds based on biopolymers and MOFs have presented great potential in various applications for modern technology.
Recent advances in the synthesis of organic chloramines and their insights into health care
Organic nitrogen–chlorine compounds and their derivatives are important heterocyclic motifs, exhibiting applications such as N-chlorinating agents, analytical reagents, disinfectants, antipathogens, and as synthetic intermediates for drugs, polymers, and natural products.
Interface design of carbon filler/polymer composites for electromagnetic interference shielding
The main three methods of interface design for carbon/polymer composites for different carbon materials.
About this collection
The web collection is comprised of the Focus and Perspective articles published in New Journal of Chemistry in 2021.