Health functions and structure–activity relationships of natural anthraquinones from plants
Anthraquinone compounds with the anthraquinone ring structure are widely found in traditional Chinese medicines and they are attracting a lot of attention due to their good pharmacological activity.
The relationship between lipid phytochemicals, obesity and its related chronic diseases
This review focuses on phytochemicals in oils, and summarizes the mechanisms of the anti-obesity effects of these compounds in in vitro studies, animal models, and human trials.
The effects of resveratrol supplementation on biomarkers of inflammation and oxidative stress among patients with metabolic syndrome and related disorders: a systematic review and meta-analysis of randomized controlled trials
The effect of resveratrol supplementation on biomarkers of inflammation and oxidative stress among patients with metabolic syndrome are controversial.
Cardioprotection and natural polyphenols: an update of clinical and experimental studies
Mechanisms involved in ischemia–reperfusion injury.
Preventive mechanism of bioactive dietary foods on obesity-related inflammation and diseases
This review focuses on the molecular biological mechanism of obesity-induced inflammation and the reciprocal interactions between the major molecular mechanisms and a range of dietary bioactive compounds.
Bioactive compounds and pharmacological and food applications of Syzygium cumini – a review
The present review explores the nutritional, phytochemical and pharmacological potential as well as diverse food usages of Syzygium cumini.
Emerging opportunities in exploring the nutritional/functional value of amaranth
Amaranthus spp. is a highly nutritive pseudocereal, rich in macronutrients and micronutrients, including vitamins and minerals.
Microbiota-accessible pectic poly- and oligosaccharides in gut health
The current review highlights the role and applications of pectin-derived poly- and oligosaccharides in the health and wellbeing of the gut.
Aspalathus linearis (Rooibos) – a functional food targeting cardiovascular disease
Aspalathus linearis (Rooibos) is a promising candidate which may impact cardiovascular disease (CVD). This review integrates relevant literature on the therapeutic potential of Rooibos in this context.
Probiotics, mechanisms of action, and clinical perspectives for diarrhea management in children
Mechanisms of action of probiotics against enteric pathogens.
Molecular mechanisms of the anti-obesity effect of bioactive ingredients in common spices: a review
The mechanisms of the anti-obesity effects of bioactive compounds in common spices in adipocytes, animal models and human participants have been reviewed.
The effects of gut microbiota on metabolic outcomes in pregnant women and their offspring
Metabolic diseases such as gestational diabetes mellitus and obesity during pregnancy have become severe health issues due to adverse pregnant outcomes in recent years.
Chemopreventive effects of some popular phytochemicals on human colon cancer: a review
The present review summarizes (1) the epidemiology and etiology of colon cancer, (2) generalized cancer chemoprotective mechanisms, and (3) the chemopreventive properties of some popular phytochemicals as well as some phytochemicals developed by our research group recently.
Modulation of intestinal epithelium homeostasis by extra virgin olive oil phenolic compounds
Extra virgin olive oil polyphenols concentrate at the intestinal level and, by modulating the microbiota, oxidative status and inflammation, contribute to prevent the onset or delay the progression of inflammatory/degenerative diseases.
Deconstructing the physical processes of digestion: reductionist approaches may provide greater understanding
I provide a broad overview of the physical factors that govern intestinal digestion with a view to outlining the quantitative work that is required to determine the relative importance of these factors in the digestion of particular foods.
Lactose malabsorption and intolerance: a review
A review on the current knowledge about lactose malabsorption and intolerance is presented including biochemistry, physiology, diagnosis and dietary management.
Science behind the cardio-metabolic benefits of omega-3 polyunsaturated fatty acids: biochemical effects vs. clinical outcomes
Lower incidence of cardiovascular disease (CVD) in the Greenland Inuit, Northern Canada and Japan has been attributed to their consumption of seafood rich in long chain omega-3 polyunsaturated fatty acids (LCn-3PUFA).
Chaperone-like food components: from basic concepts to food applications
The significance of chaperones in preventing protein aggregation including amyloid fibril formation has been extensively documented in the biological field, but there is limited research on the potential effect of chaperone-like molecules on food protein functionality and food quality.
Triterpenoid saponins from the genus Camellia: structures, biological activities, and molecular simulation for structure–activity relationship
This review summarizes the isolation, chemical identification, and biochemical activities of Camellia triterpenoid saponins, updating a previous review and encompassing all new studies through September 2017.
Dietary fibers, prebiotics, and exopolysaccharides produced by lactic acid bacteria: potential health benefits with special regard to cholesterol-lowering effects
Lactic acid bacteria (LAB)-based exopolysaccharides (EPS) potentially have prebiotic properties and could be natural alternatives for the treatment of hypercholesterolemia.
New highlights on the health-improving effects of sulforaphane
In this paper, we review recent evidence about the beneficial effects of sulforaphane (SFN), which is the most studied member of isothiocyanates, on both in vivo and in vitro models of different diseases, mainly diabetes and cancer.
Fruit and vegetable consumption and the risk of postmenopausal osteoporosis: a meta-analysis of observational studies
The association of the consumption of fruit and vegetables (FV) and the risk of postmenopausal osteoporosis (PMOP) has been a controversial subject.
Soy product consumption and the risk of all-cause, cardiovascular and cancer mortality: a systematic review and meta-analysis of cohort studies
Currently, the association of soy intake with total- and cause-specific mortality is inconsistent.
Anti-aging potential of tree nuts with a focus on the phytochemical composition, molecular mechanisms and thermal stability of major bioactive compounds
Tree nuts, complete functional foods, contain macro- and micronutrients of high biological value.
Citrus medica: nutritional, phytochemical composition and health benefits – a review
Health benefits and products of Citrus medica.
Dietary impact on esophageal cancer in humans: a review
Foods and the risk of esophageal cancer.
Safety considerations of plant polysaccharides for food use: a case study on phenolic-rich softwood galactoglucomannan extract
A growing population and concern over the sufficiency of natural resources for feeding this population have motivated researchers and industries to search for alternative and complementary sources of food ingredients and additives.
Effects of superfoods on risk factors of metabolic syndrome: a systematic review of human intervention trials
A new term was introduced recently to describe foods with additional health benefits: “superfoods”, for which up to date no generally accepted definitions exist. Nonetheless, their consumption might contribute to the prevention of metabolic syndrome.
Complementary effects of cereal and pulse polyphenols and dietary fiber on chronic inflammation and gut health
Cereal and pulse polyphenols and dietary fiber offer a wealth of complementary health benefits.
Gut : liver : brain axis: the microbial challenge in the hepatic encephalopathy
Gut microbiota modulation to restore proper gut : brain axis communications and reduce cirrhosis associated symptoms and HE progression.
Circular reuse of bio-resources: the role of Pleurotus spp. in the development of functional foods
Pleurotus spp. grown on clean processing by-products is an ingredient that links food sustainability with functionality.
Processing of oat: the impact on oat's cholesterol lowering effect
Human studies have clearly demonstrated the beneficial impact of consuming oats on cholesterol levels, however, processing can have a significant influence on functionality, which has not yet been fully addressed.
Revisiting the carrageenan controversy: do we really understand the digestive fate and safety of carrageenan in our foods?
An overview of evidence on Carrageenan (CGN), a family of marine polysaccharides, their characteristics and digestive fate that highlight various gaps in our understanding.
Interactions between wine phenolic compounds and human saliva in astringency perception
This review summarizes recent trends in methodologies based on the salivary protein–phenol interaction to determine astringency and the factors affecting this interaction.
Occurrence, biological activity and metabolism of 6-shogaol
As one of the main bioactive compounds of dried ginger, 6-shogaol has been widely used to alleviate many ailments.
Diet and microbiota linked in health and disease
Diet has shaped microbiota profiles through human evolution.
Edible oleogels: an opportunity for fat replacement in foods
The number of publications, as a result of searching for hydrogels and oleogels for food applications in the last 10 years, shows that oleogels are getting more attention while hydrogels remain as a topic of interest. Moreover, the increasing number of publications dealing with food and obesity reveals that the food industry still has an important role in this regard.
Interactions of flavonoids with α-amylase and starch slowing down its digestion
Hydrophobic flavonoids can suppress starch digestion in the intestine by forming starch-flavonoid complexes.
Association between berries intake and cardiovascular diseases risk factors: a systematic review with meta-analysis and trial sequential analysis of randomized controlled trials
The main goal of this work was to clarify the effects of the consumption of berries on cardiovascular disease (CVD) risk factors by performing a systematic review followed by a meta-analysis and a trial sequential analysis (TSA).
Research into food portion size: methodological aspects and applications
In-depth review of methods used in portion size research including dietary, cognitive and behavioural instruments.
Curcumin as a functional food-derived factor: degradation products, metabolites, bioactivity, and future perspectives
Challenges and future perspectives of curcumin health benefit research.
Dietary fruits and arthritis
Arthritis is a global health concern affecting a significant proportion of the population and associated with reduced quality of life.
Molecular targets and mechanisms of bioactive peptides against metabolic syndromes
Bioactive peptides have beneficial effects on blood pressure, inflammation, obesity, and T2D, indicating their great potential as functional foods/nutraceuticals against metabolic syndromes.
Molecular actions of hypocholesterolaemic compounds from edible mushrooms
Edible mushrooms contain bioactive compounds able to modulate the expression of genes related to absorption, biosynthesis and transport of cholesterol and regulation of its homeostasis.
Enhanced delivery of lipophilic bioactives using emulsions: a review of major factors affecting vitamin, nutraceutical, and lipid bioaccessibility
Many researchers are currently developing emulsion-based delivery systems to increase the bioavailability of lipophilic bioactive agents, such as oil-soluble vitamins, nutraceuticals, and lipids. This article reviews recent research in this area.
About this collection
Food and Function publishes authoritative and insightful review articles covering all aspects of the journal scope. In this collection, we have brought together recent reviews published in the journal – we hope you enjoy reading them.