Themed collection Recent Review Articles
Molecular mechanisms from insulin-mimetic effect of vitamin D: treatment alternative in Type 2 diabetes mellitus
Type 2 diabetes mellitus is characterized by a state of insulin resistance, which leads to metabolic alterations that aggravate the state of health of people.
Food Funct., 2021,12, 6682-6690
https://doi.org/10.1039/D0FO03230A
Therapeutic perspectives of the black cumin component thymoquinone: A review
The dietary phytochemical thymoquinone, obtained from the black and angular seeds of Nigella sativa, is a promising monoterpenoid hydrocarbons, which has been receiving massive attention for its therapeutic potential and pharmacological properties.
Food Funct., 2021,12, 6167-6213
https://doi.org/10.1039/D1FO00401H
Gut microbiota in mental health and depression: role of pre/pro/synbiotics in their modulation
A review of antidepressant mechanisms via gut microbe alterations with insight into how they can provide an alternative to antidepressant therapy without the side effects and risk of adverse drug reactions.
Food Funct., 2021,12, 4284-4314
https://doi.org/10.1039/D0FO02855J
Potential beneficial effects of kefir and its postbiotic, kefiran, on child food allergy
Food allergies are known as the public health problem, affecting people of all age groups, but more commonly in babies and children, with consequences for nutritional status and quality of life.
Food Funct., 2021,12, 3770-3786
https://doi.org/10.1039/D0FO03182H
Fucoidan: a promising agent for brain injury and neurodegenerative disease intervention
Fucoidan exerts a neuroprotective function on neurodegenerative diseases and brain injury by inhibiting inflammation, oxidative stress, apoptosis, mitochondrial dysfunction and microglial activation, while activating neurite outgrowth and the cholinergic system.
Food Funct., 2021,12, 3820-3830
https://doi.org/10.1039/D0FO03153D
Role of honey in preventing radiation-induced oral mucositis: a meta-analysis of randomized controlled trials
Honey is a natural substance with antioxidant properties. Honey can prevent and reduce oral mucositis caused by radiation and relieve severe pain.
Food Funct., 2021,12, 3352-3365
https://doi.org/10.1039/D0FO02808H
Plant-derived melatonin from food: a gift of nature
The Chinese fairy tale of Shennong, the god of agriculture in China, who tasted hundreds of grasses to find foods and herbs for humans during the legend period.
Food Funct., 2021,12, 2829-2849
https://doi.org/10.1039/D0FO03213A
Research progress on the potential delaying skin aging effect and mechanism of tea for oral and external use
Tea for oral and external use can anti-UV, antioxidant, anti-inflammatory, inhibit the aging of extracellular matrix, balance intestinal and skin microorganisms, improve mood and sleep, and fundamentally make the skin healthy and natural aging.
Food Funct., 2021,12, 2814-2828
https://doi.org/10.1039/D0FO02921A
Efficacy of probiotics in multiple sclerosis: a systematic review of preclinical trials and meta-analysis of randomized controlled trials
Preliminary evidence shows the potential role of probiotics in ameliorating multiple sclerosis (MS); however, the effects of probiotics on MS remain unclear.
Food Funct., 2021,12, 2354-2377
https://doi.org/10.1039/D0FO03203D
Effects of brown seaweed polyphenols, a class of phlorotannins, on metabolic disorders via regulation of fat function
It is well known that fat dysfunction is the main driver of development of metabolic disorders.
Food Funct., 2021,12, 2378-2388
https://doi.org/10.1039/D0FO02886J
The role of emerging micro-scale vegetables in human diet and health benefits—an updated review based on microgreens
Microgreens as good sources of nutritional and bioactive compounds play an increasingly vital role in health-promoting diets.
Food Funct., 2021,12, 1914-1932
https://doi.org/10.1039/D0FO03299A
Research progress on separation of selenoproteins/Se-enriched peptides and their physiological activities
Extracting Se-enriched proteins and peptides from Se-enriched agricultural products is crucial for improving the nutritional status of Se in the population.
Food Funct., 2021,12, 1390-1401
https://doi.org/10.1039/D0FO02236E
The interaction between tea polyphenols and host intestinal microorganisms: an effective way to prevent psychiatric disorders
Tea polyphenols (TP) are the most bioactive components in tea extracts.
Food Funct., 2021,12, 952-962
https://doi.org/10.1039/D0FO02791J
The role of natural products in the prevention and treatment of pulmonary fibrosis: a review
Natural products prevent and treat pulmonary fibrosis by regulating oxidative stress, inflammatory injury, epithelial–mesenchymal transition (EMT), fibroblast activation and metabolic disorders.
Food Funct., 2021,12, 990-1007
https://doi.org/10.1039/D0FO03001E
Advances in the preparation and assessment of the biological activities of chitosan oligosaccharides with different structural characteristics
The bioactivity of chitosan oligosaccharides (COSs) is closely related to the amino groups, acetyl groups, hydroxyl groups and degree of polymerization of their molecular structure, and to their molecular weight.
Food Funct., 2021,12, 926-951
https://doi.org/10.1039/D0FO02768E
The impact of a high fat diet on bones: potential mechanisms
High-fat diet led to bone loss via gut microbiota and fatty acid imbalances, immune disorder and adipose tissue accumulation inside and outside the bone marrow.
Food Funct., 2021,12, 963-975
https://doi.org/10.1039/D0FO02664F
Recent progress in polysaccharides from Panax ginseng C. A. Meyer
Panax ginseng C. A. Meyer (P. ginseng) has a long history of medicinal use and can treat a variety of diseases.
Food Funct., 2021,12, 494-518
https://doi.org/10.1039/D0FO01896A
Food buffering capacity: quantification methods and its importance in digestion and health
Understanding the influence of food properties on buffering capacity will have an impact on gastric secretions and breakdown during digestion.
Food Funct., 2021,12, 543-563
https://doi.org/10.1039/D0FO02415E
A recent update on the multifaceted health benefits associated with ginger and its bioactive components
The bioactive compounds and bioactivities of ginger, and their detailed mechanisms including some therapeutic effects of ginger and its constituents for effective antioxidant properties were comprehensive reviewed.
Food Funct., 2021,12, 519-542
https://doi.org/10.1039/D0FO02834G
Vegetarian diets during pregnancy: effects on the mother's health. A systematic review
While interest in vegetarian nutrition has been steadily increasing, some aspects have not yet been consistently investigated.
Food Funct., 2021,12, 466-493
https://doi.org/10.1039/D0FO01991G
The role of yoghurt consumption in the management of type II diabetes
Enrichment of yoghurt with specific ingrdients beneficially affects the management of Type II Diabetes Mellitus (DMII).
Food Funct., 2020,11, 10306-10316
https://doi.org/10.1039/D0FO02297G
Dietary natural methylxanthines and colorectal cancer: a systematic review and meta-analysis
Some evidence suggests that caffeine, theophylline, and theobromine, as natural methylxanthines (MTXs), possess anti-cancer effects.
Food Funct., 2020,11, 10290-10305
https://doi.org/10.1039/D0FO02518F
Is it scientifically justifiable to exclude wine and/or unfermented grape derivatives from the diet of consumers with or at risk of developing type-2 diabetes?
This narrative review investigates whether low/moderate consumption of wine/grape's derivatives can be part of T2D individuals daily diet.
Food Funct., 2020,11, 10266-10278
https://doi.org/10.1039/D0FO01969K
The impact of probiotic supplementation on metabolic health in healthy women of reproductive age: a systematic review
Products containing probiotics are targeted at healthy or at-risk individuals as a preventative measure to minimise disease risk.
Food Funct., 2020,11, 10279-10289
https://doi.org/10.1039/D0FO01727B
Insights into the potential benefits of black soybean (Glycine max L.) polyphenols in lifestyle diseases
Black soybean (Glycine max L.), a cultivar containing abundant polyphenols in its seed coat such as anthocyanins and flavan-3-ols, has been reported to possess various health benefits toward lifestyle diseases.
Food Funct., 2020,11, 7321-7339
https://doi.org/10.1039/D0FO01092H
Anti-obesity effects of capsaicin and the underlying mechanisms: a review
The mechanisms of anti-obesity effects of capsaicin in cell models, rodent models and human subjects were reviewed.
Food Funct., 2020,11, 7356-7370
https://doi.org/10.1039/D0FO01467B
The potential roles of chitosan oligosaccharide in prevention of kidney injury in obese and diabetic conditions
Potential effects of COS and the possible mechanisms.
Food Funct., 2020,11, 7371-7388
https://doi.org/10.1039/D0FO00302F
The effect of almond intake on anthropometric indices: a systematic review and meta-analysis
This systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted to summarize the effect of almond intake on anthropometric indices in adult subjects.
Food Funct., 2020,11, 7340-7355
https://doi.org/10.1039/D0FO00470G
An overview and update on the epidemiology of flavonoid intake and cardiovascular disease risk
Higher intakes of flavonoid-rich foods are associated with a lower risk of cardiovascular disease in prospective cohort studies.
Food Funct., 2020,11, 6777-6806
https://doi.org/10.1039/D0FO01118E
The effects of betalain-rich cacti (dragon fruit and cactus pear) on endothelial and vascular function: a systematic review of animal and human studies
This systematic review assesses the evidence for the effects of edible cacti (dragon fruit and cactus pear) on vascular and endothelial function based on animal models and human studies.
Food Funct., 2020,11, 6807-6817
https://doi.org/10.1039/D0FO00537A
The digestion of galactolipids and its ubiquitous function in Nature for the uptake of the essential α-linolenic acid
Galactolipases allow the digestion of galactolipids, the most abundant lipids on Earth and the main source of α-linolenic acid.
Food Funct., 2020,11, 6710-6744
https://doi.org/10.1039/D0FO01040E
Dietary bioactive ingredients to modulate the gut microbiota-derived metabolite TMAO. New opportunities for functional food development
Diet could play a dual role in the production of the TMA/TMAO meta-organismal pathway since it provides TMA precursors, but also other dietary constituents that reduce endogenous TMAO or its damaging effects through different mechanisms.
Food Funct., 2020,11, 6745-6776
https://doi.org/10.1039/D0FO01237H
Anti-stress effects of polyphenols: animal models and human trials
Relationship between “stressors” and “stress responses”, such as hormone secretion. Some polyphenols can prevent stress responses, which subsequently prevent stress-related health problems.
Food Funct., 2020,11, 5702-5717
https://doi.org/10.1039/D0FO01129K
Application of microfluidic technology in food processing
Microfluidic technology is interdisciplinary with a diversity of applications including in food processing.
Food Funct., 2020,11, 5726-5737
https://doi.org/10.1039/D0FO01278E
Health beneficial effects of resistant starch on diabetes and obesity via regulation of gut microbiota: a review
Resistant starch (RS) is well known to prevent type 2 diabetes mellitus (T2DM) and obesity.
Food Funct., 2020,11, 5749-5767
https://doi.org/10.1039/D0FO00855A
Pomegranate juice as a functional food: a comprehensive review of its polyphenols, therapeutic merits, and recent patents
A review on pomegranate juice as a functional food in the context of its polyphenol composition, therapeutic merits, and recent patents.
Food Funct., 2020,11, 5768-5781
https://doi.org/10.1039/D0FO01251C
The influence of traditional and new processing technologies on the structure and function of food polysaccharide
The influence of traditional processing technologies and new technologies on the structure and function of food polysaccharide was investigated and discussed.
Food Funct., 2020,11, 5718-5725
https://doi.org/10.1039/D0FO00854K
An overview on the biosynthesis and metabolic regulation of monacolin K/lovastatin
Lovastatin/monacolin K (MK) is used as a lipid lowering drug, due to its effective hypercholesterolemic properties, comparable to synthetic statins.
Food Funct., 2020,11, 5738-5748
https://doi.org/10.1039/D0FO00691B
Synergic interactions between polyphenols and gut microbiota in mitigating inflammatory bowel diseases
Polyphenols and gut microbiota act separately and synergistically to alleviate inflammatory bowel diseases.
Food Funct., 2020,11, 4878-4891
https://doi.org/10.1039/D0FO00713G
Research progress on the biological activities of selenium polysaccharides
Selenium polysaccharides, an important organic selenium product, possess better antioxidant, antitumour, immune regulation, hypoglycaemic, and heavy metal removal activities than that of either polysaccharides or inorganic selenium.
Food Funct., 2020,11, 4834-4852
https://doi.org/10.1039/C9FO02026H
Protection against developing type 2 diabetes by coffee consumption: assessment of the role of chlorogenic acid and metabolites on glycaemic responses
Coffee chlorogenic acids do not affect carbohydrate digestion directly, but modulate glucose absorption/utilisation, the latter through endogenous/gut microbiota metabolites.
Food Funct., 2020,11, 4826-4833
https://doi.org/10.1039/D0FO01168A
Agriculture waste valorisation as a source of antioxidant phenolic compounds within a circular and sustainable bioeconomy
Agro-food industrial waste is currently being accumulated, pushing scientists to find recovery strategies to obtain bioactive compounds within a circular bioeconomy. Target phenolic compounds have shown market potential by means of optimization extraction techniques.
Food Funct., 2020,11, 4853-4877
https://doi.org/10.1039/D0FO00937G
Effects of fasting intervention regulating anthropometric and metabolic parameters in subjects with overweight or obesity: a systematic review and meta-analysis
Previous studies have shown that fasting produces a potential effect in the prevention and treatment of many diseases.
Food Funct., 2020,11, 3781-3799
https://doi.org/10.1039/D0FO00287A
Inflammation and cardiovascular disease: are marine phospholipids the answer?
This review presents the latest research on the cardioprotective effects of n-3 fatty acids (FA) and n-3 FA bound to polar lipids (PL). Overall, n-3 PL may have enhanced bioavailability and potentially bioactivity versus free FA and ester forms of n-3 FA.
Food Funct., 2020,11, 2861-2885
https://doi.org/10.1039/C9FO01742A
Impact of functional foods and nutraceuticals on high blood pressure with a special focus on meta-analysis: review from a public health perspective
In recent times many researchers are expressing immense interest in nutraceuticals and functional foods for combating various diseases or abnormal conditions, especially against hypertension (HT).
Food Funct., 2020,11, 2792-2804
https://doi.org/10.1039/D0FO00357C
Quantifying dietary vitamin K and its link to cardiovascular health: a narrative review
Potential beneficial pathways by which vitamin K may reduce the risk of cardiovascular disease mortality.
Food Funct., 2020,11, 2826-2837
https://doi.org/10.1039/C9FO02321F
Capsaicin—the major bioactive ingredient of chili peppers: bio-efficacy and delivery systems
The mechanisms of bio-efficacy of capsaicin and delivery systems with enhanced bioavailability were reviewed.
Food Funct., 2020,11, 2848-2860
https://doi.org/10.1039/D0FO00351D
The effect of taste and taste perception on satiation/satiety: a review
As the prevalence of being overweight and obesity has increased worldwide, there is an increasing concern about satiation/satiety that can be achieved by eating.
Food Funct., 2020,11, 2838-2847
https://doi.org/10.1039/C9FO02519G
Insight into the potential application of polyphenol-rich dietary intervention in degenerative disease management
In recent times, a great number of plants have been studied in order to identify new components with nutraceutical properties, among which are polyphenols.
Food Funct., 2020,11, 2805-2825
https://doi.org/10.1039/D0FO00216J
Effects of eicosapentaenoic acid and docosahexaenoic acid versus α-linolenic acid supplementation on cardiometabolic risk factors: a meta-analysis of randomized controlled trials
Previous randomized controlled trials (RCTs) made direct comparisons between EPA/DHA versus ALA on improving cardiovascular risk factors and have reached inconsistent findings.
Food Funct., 2020,11, 1919-1932
https://doi.org/10.1039/C9FO03052B
The potential of proteins, hydrolysates and peptides as growth factors for Lactobacillus and Bifidobacterium: current research and future perspectives
Probiotics are live microorganisms that provide health benefits to the host when consumed in adequate concentrations.
Food Funct., 2020,11, 1946-1957
https://doi.org/10.1039/C9FO02961C
Future foods: a manifesto for research priorities in structural design of foods
Modern food science is creating safer, healthier & more sustainable foods.
Food Funct., 2020,11, 1933-1945
https://doi.org/10.1039/C9FO02076D
The effects of caloric restriction and its mimetics in Alzheimer's disease through autophagy pathways
AD is a neurodegenerative disease that commonly occurs among older individuals. Caloric restriction and its mimetics have been shown to alleviate amyloid burden, tau pathology, and improve cognitive function of rodent models of AD by activating autophagy.
Food Funct., 2020,11, 1211-1224
https://doi.org/10.1039/C9FO02611H
Sesamol: a powerful functional food ingredient from sesame oil for cardioprotection
Phytophenols are important bioactive food based chemical entities, largely present in several natural sources.
Food Funct., 2020,11, 1198-1210
https://doi.org/10.1039/C9FO01873E
Medicinal effects of Peruvian maca (Lepidium meyenii): a review
Peruvian maca (Lepidium meyenii) is a root native to the Andean region, cultivated for at least 2000 years.
Food Funct., 2020,11, 83-92
https://doi.org/10.1039/C9FO02732G
Effects of short-term consumption of strawberry powder on select parameters of vascular health in adolescent males
In both children and adults, dietary interventions strongly supports the concept that the regular consumption of strawberries can be associated with improvements in cardiovascular health.
Food Funct., 2020,11, 32-44
https://doi.org/10.1039/C9FO01844A
About this collection
Food and Function publishes authoritative and insightful review articles covering all aspects of the journal scope. In this collection, we have brought together recent reviews published in the journal – we hope you enjoy reading them.