Themed collection 2013's Top 25 most read Analyst articles
Advances in nano-scaled biosensors for biomedical applications
This review focuses on the recent advances of nano-scaled biosensors for disease diagnosis and bio-marking, including their efficient utilization in bio-imaging and the monitoring of pathological cells and viruses as well as pathogenic bacteria.
Antibody orientation on biosensor surfaces: a minireview
This review outlines methods to orient antibodies onto a surface, to study their orientation, and the significant effects of orientation on biosensing.
Nanoparticle-based immunoassays in the biomedical field
This minireview summarizes recent advances in nanoparticle-based electrochemical, optical, mass-sensitive, colorimetric and immunodipstick assays, focusing on novel concepts and promising applications.
Rational design and synthesis of
Surface-enhanced Raman scattering (SERS) labels are a new class of nanotags for optical detection. Physical and chemical concepts for the rational design and synthesis of SERS labels including their bioconjugation are summarized.
ATR-FTIR spectroscopic imaging: recent advances and applications to biological systems
A tutorial review on ATR-FTIR imaging: a versatile, label-free and chemical specific imaging method for the analysis of biological systems.
Graphene and its derivatives for cell biotechnology
The focus of this Tutorial Review is to emphasize the current situation and significance of using this new kind of two-dimensional material in the hot and emerging fields that are closely related to human life quality, for instance, cell biochemistry, bioimaging along with other frontier areas.
Illuminating disease and enlightening biomedicine: Raman spectroscopy as a diagnostic tool
An introduction to some of the more exciting recent advances and dynamic current areas of development in biomedical Raman spectroscopy.
Quantum dots for fluorescent biosensing and bio-imaging applications
This review focuses on quantum dot-based fluorescent biosensing for proteins and nucleic acids detection, as well as the use of QDs in cellular and in vivo targeting and imaging.
Lipid imaging by mass spectrometry – a review
A comprehensive review of current mass spectrometry imaging techniques and their application to lipids.
Recent advances in fluorescent nucleic acid probes for living cell studies
General requirements for, design schemes and recent developments in fluorescent nucleic acid probes for living cells are reviewed and discussed.
Electrogenerated chemiluminescence of nanomaterials for bioanalysis
Recent advances in the electrochemiluminescence of nanomaterials and their application in bioanalysis are reviewed.
A turn-on and reversible
Schiff base fluorescence sensor for Al3+ ion
A simple Schiff-base receptor 2 was prepared. It exhibits an “off-on-type” mode with high sensitivity in the presence of Al3+.
A novel near-infrared
fluorescent probe for selectively sensing nitroreductase (NTR) in an aqueous medium
A novel near-infrared fluorescence probe was developed for NTR detection with excellent selectivity over 100 equiv. of other biological reductants.
A highly selective and efficient single molecular FRET based sensor for ratiometric detection of Fe3+ ions
A selective and efficient FRET based sensor for the ratiometric detection of Fe3+ in aqueous and biological samples is presented.
Amidine-based fluorescent chemosensor with high applicability for detection of CO2: A facile way to “see” CO2
An amidine-based fluorescent chemosensor for CO2 has been prepared and has unique sensitivity to CO2, extraordinarily high water-resistance and no issue with carbon monoxide-interference.
Capillary zone electrophoresis-multiple reaction monitoring from 100 pg of RAW 264.7 cell lysate digest
Capillary zone electrophoresis-multiple/single reaction monitoring (CZE-MRM/SRM), which employed an electrokinetically driven sheath-flow electrospray interface, was used for the rapid and highly sensitive detection of protein analytes in complex tryptic digests.
Controllable synthesis of
silver nanoparticle-decorated reduced graphene oxide hybrids for ammonia detection
A controllable fabrication of Ag nanoparticle-decorated reduced graphene oxide (RGO/Ag) hybrids and their application for fast and selective detection of room-temperature ammonia were demonstrated.
A non enzymatic glucose biosensor based on an ultrasensitive calixarene functionalized boronic acid gold nanoprobe for sensing in human blood serum
We developed a new, advanced, simple and non enzymatic approach for the colorimetric detection of glucose based on calixarene/phenyl boronic acid (CX-PBA) functionalized gold nanoparticles (AuNPs).
Protein amyloids develop an intrinsic fluorescence signature during aggregation
A structure-specific intrinsic fluorescence develops during the aggregation of a range of disease-relevant human polypeptides including amyloid-beta, lysozyme and tau.
quantum dot-based “off–on” fluorescent probe for biological detection of zinc ions
A quantum dots-based fluorescence “off–on” probe for biological Zn2+ detection with high sensitivity and selectivity has been developed.
Electrogenerated chemiluminescence detection of trace level pentachlorophenol using carbon quantum dots
The environmental pollutant pentachlorophenol (PCP) is detected using a combination of carbon quantum dots and platinum as the working electrode. A detection limit of 1.3 × 10−12 g L−1 is achieved.
SERS dipsticks and swabs for trace chemical detection
We demonstrate a surface swab and lateral-flow dipstick that includes an inkjet-printed surface-enhanced Raman spectroscopy (SERS) substrate for analyte detection.
Fluorescent probe for highly selective and sensitive detection of hydrogen sulfide in living cells and cardiac tissues
H2S visualization is successfully achieved in cells and cardiac tissues with a coumarin-based fluorescence probe.
Polydopamine-based molecular imprinting on silica-modified magnetic nanoparticles for recognition and separation of bovine hemoglobin
Polydopamine-based molecular imprinted film on silica–Fe3O4 nanoparticles shows relatively high adsorption capacity and excellent selectivity towards bovine hemoglobin.
Tattoo-based potentiometric ion-selective sensors for epidermal pH monitoring
Temporary transfer tattoo-based all-solid contact potentiometric sensors are fabricated by combining screen printing, temporary tattoo and conducting polymer technology and evaluated for real-time epidermal pH monitoring.