RSC Advances  

An efficient and mild approach has been developed for the regio-selective direct C3 halogenation of pyrazolo[1,5-a]pyrimidines employing readily available potassium halide salts and a hypervalent iodine(III) reagent at ambient temperature.

Starch as catalyst for organic reactions.

A mild, efficient and convenient procedure for the acetylation of alcohols with EtOAc as acetyl source and solvent mediated by KOH was reported.

An electrochemical approach to access seleno-benzazepines through an oxidative radical cascade cyclization of dienes with diselenides under metal-free, external oxidant-free and base-free conditions.

Bicyclic guanidines are utilized in organic synthesis as base catalysts or reagents.

In this work, a comparison between the catalytic activity of two piperazine based ionic liquids immobilized on ZnO NPs and SiO₂ NPs is presented in the synthesis of benzoxazoles and benzimidazoles.

Among the diverse natural catalysts, caffeine has emerged as a green, expedient, non-toxic, and biodegradable catalyst. The main objective of this review is to present the existing knowledge pertaining to the exploitation of caffeine in various organic transformations.

A sustainable and environmentally friendly approach was devised for the synthesis of bioactive hybrids, which were subsequently assessed for their antimicrobial efficacy.

The efficacy of green solvents and neat conditions in organocatalysed reactions were investigated. The results suggest cyclopentyl methyl ether and neat conditions could serve as alternatives, potentially enhancing the processes' sustainability.

We developed a mild and environmentally friendly electrochemical method for the synthesis of quinazolines and quinazolinones via electrochemical oxidative decarboxylation of α-oxocarboxylic acids.

The demand for a wide array of functional chemicals and materials has experienced a significant surge in tandem with the advancement of civilization.

A ligand-free copper-catalyzed cyclization method is shown for synthesizing benzimidazoles and optimized process of benzimidazoles from cheap o-bromoarylamine and nitriles.

We developed a solvent-free, mild, and efficient protocol for Heck–Mizoroki reactions under ultrasonic irradiation in open air, which would be predictable and robust using a range of substrates.

An efficient metal-free single-step protocol has been developed for the direct synthesis of flavones from 2-hydroxyacetophenone and substituted benzaldehydes.

A variety of bioactive compounds can be synthesized via C–C and C–X (X = O/S/N/Se/Cl/Br) bond formation using an efficient catalytic system I₂/DMSO. This review highlights the progress and identifies potential paths for future research in this field.

Spiro heterocycle frameworks are a class of organic compounds that possesses unique structural features making them highly sought-after targets in drug discovery due to their diverse biological and pharmacological activities.

A facile method was developed for the selective thioetherification of uracils using sulfonyl hydrazide as the thioetherification reagent.

A practical and sustainable metal-, additive-free olefination approach is proposed for the facile synthesis of various N-heteroazaarenes with high regioselectivity from simple methyl-substituted heteroarenes and amines using air as the oxidant.

Photocatalysis has proven to be an effective approach for the production of reactive intermediates under moderate reaction conditions.

Bis(3-indolyl)methanes (BIMs) are known for their important bioactivities, which include anti-cancer, anti-inflammatory, antibacterial, and antioxidant properties.

The reactions and mechanisms of alkynes that are involved in multi-component reactions through C–C and C–H positions are investigated.

Herein, we developed a palladium-catalysed C–H cyclisation of benzoic acids in chlorobenzene without additional oxidants.

A photocatalytic strategy has been developed for the selective synthesis of (E)-β-aminovinyl sulfones and (E)-β-amidovinyl sulfones through the utilization of allenamides and sodium sulfinates.

Growing demand for eco-friendly catalysts in drug synthesis. Fe₃O₄@AMBA-CuI nanomaterials, a reusable catalyst, enable synthesis of diaryl and di-heteroaryl sulfides from diverse substrates. Reusability tests confirm stability, maintaining magnetic properties through six uses, yielding sulfides.

A facile electrochemical oxidative and radical cascade cyclization of N-(2-vinylphenyl)amides with CF₃SO₂Na was conducted to synthesize the CF₃-containing benzoxazines and oxazolines.