Themed collection Lab on a Chip Recent Open Access Articles
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Personalised organs-on-chips: functional testing for precision medicine
Organs-on-chips can be ‘personalised’ so they can be used as functional tests to inform clinical decision-making for specific patients.
Lab Chip, 2019,19, 198-205
https://doi.org/10.1039/C8LC00827B
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Maximizing the impact of microphysiological systems with in vitro–in vivo translation
The full impact of MPS technologies will be realized only when robust approaches for in vitro–in vivo (MPS-to-human) translation are developed and utilized.
Lab Chip, 2018,18, 1831-1837
https://doi.org/10.1039/C8LC00039E
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Droplet microfluidics for the construction of compartmentalised model membranes
This tutorial review explores the use of droplet microfluidics to generate compartmentalised model membrane constructs that have potential applications as microreactors, as artificial cells in synthetic biology, as simplified cell models and as drug delivery vehicles.
Lab Chip, 2018,18, 2488-2509
https://doi.org/10.1039/C8LC00028J
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Integration and application of optical chemical sensors in microbioreactors
This tutorial review explains the integration of optical chemical sensor formats for the purpose of monitoring oxygen, pH, carbon dioxide, glucose and temperature in microbioreactors.
Lab Chip, 2017,17, 2693-2712
https://doi.org/10.1039/C7LC00538E
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Rotating magnetic particles for lab-on-chip applications – a comprehensive review
Magnetic particles are widely used in lab-on-chip and biosensing applications, because they have a high surface-to-volume ratio, they can be actuated with magnetic fields and many biofunctionalization options are available. This review focuses on the use of rotating magnetic particles for lab-on-chip applications.
Lab Chip, 2019,19, 919-933
https://doi.org/10.1039/C8LC01323C
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Increasing the functionalities of 3D printed microchemical devices by single material, multimaterial, and print-pause-print 3D printing
3D printing has emerged as a valuable approach for the fabrication of fluidic devices and may replace soft-lithography as the method of choice for rapid prototyping.
Lab Chip, 2019,19, 35-49
https://doi.org/10.1039/C8LC00826D
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Caring for cells in microsystems: principles and practices of cell-safe device design and operation
This review is geared towards device engineers, designers, and users who wish to establish “cell-friendly” technologies with utility to a broader scientific community.
Lab Chip, 2018,18, 3333-3352
https://doi.org/10.1039/C8LC00746B
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Capillary microfluidics in microchannels: from microfluidic networks to capillaric circuits
This review critically analyzes the history, fundamental operating principles, limitations, applications, and emerging ideas related to microchannel-based capillary microfluidics.
Lab Chip, 2018,18, 2323-2347
https://doi.org/10.1039/C8LC00458G
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Microsensor systems for cell metabolism – from 2D culture to organ-on-chip
We discuss microsensors for cell culture monitoring from 2D culture to organ-on-chip systems, including sensor principles, fabrication and culture formats.
Lab Chip, 2018,18, 1274-1291
https://doi.org/10.1039/C7LC00942A
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Wearable sensors: modalities, challenges, and prospects
Non-invasive wearable sensing technology extracts mechanical, electrical, optical, and chemical information from the human body.
Lab Chip, 2018,18, 217-248
https://doi.org/10.1039/C7LC00914C
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Recent advances in microfluidic technologies for cell-to-cell interaction studies
Microfluidic cell cultures are ideally positioned to become the next generation of in vitro diagnostic tools for biomedical research, where key biological processes such as cell signalling and dynamic cell-to-cell interactions can be reliably analysed under reproducible physiological cell culture conditions.
Lab Chip, 2018,18, 249-270
https://doi.org/10.1039/C7LC00815E
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Microfluidics for exosome isolation and analysis: enabling liquid biopsy for personalized medicine
Breakthroughs in adapting microfluidic systems for exosome isolation, detection, and analysis are providing new tools to revolutionize personalized medicine.
Lab Chip, 2017,17, 3558-3577
https://doi.org/10.1039/C7LC00592J
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Mobile microrobots for bioengineering applications
Untethered micron-scale mobile robots can navigate and non-invasively perform specific tasks inside unprecedented and hard-to-reach inner human body sites and inside enclosed organ-on-a-chip microfluidic devices with live cells.
Lab Chip, 2017,17, 1705-1724
https://doi.org/10.1039/C7LC00064B
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The lab-on-PCB approach: tackling the μTAS commercial upscaling bottleneck
Recent developments in the lab-on-PCB integration technology, highlighting its standardized industrial fabrication potential.
Lab Chip, 2017,17, 1388-1405
https://doi.org/10.1039/C7LC00121E
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Advancements in microfluidics for nanoparticle separation
Nanoparticles have been widely implemented for healthcare and nanoscience industrial applications.
Lab Chip, 2017,17, 11-33
https://doi.org/10.1039/C6LC01045H
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Waveguide-based chemo- and biosensors: complex emulsions for the detection of caffeine and proteins
Emulsion waveguides: a new modular sensing approach in which complex emulsions serve as efficient transducers in optical evanescent field-based waveguide sensors is reported.
Lab Chip, 2019,19, 1327-1331
https://doi.org/10.1039/C9LC00070D
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Flow focusing through gels as a tool to generate 3D concentration profiles in hydrogel-filled microfluidic chips
We present a novel extension of laminar flow patterning using Darcy flow within cured three-dimensional hydrogels for precise delivery of solutes.
Lab Chip, 2019,19, 206-213
https://doi.org/10.1039/C8LC01140K
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Biomolecular recognition on nanowire surfaces modified by the self-assembled monolayer
Biomolecular recognition can be attained by using the self-assembled monolayer modification for capture of a target analyte on the nanowire surfaces instead of primary antibodies.
Lab Chip, 2018,18, 3225-3229
https://doi.org/10.1039/C8LC00438B
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A simple and low-cost chip bonding solution for high pressure, high temperature and biological applications
An adhesive-based strategy for the low-cost and reversible sealing of a wide range of materials used in microfluidics, requiring only the application of manually-achievable pressures.
Lab Chip, 2017,17, 629-634
https://doi.org/10.1039/C6LC01319H
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On-chip integration of organic synthesis and HPLC/MS analysis for monitoring stereoselective transformations at the micro-scale
Seamless on-chip integration of a micro reaction unit and an HPLC functionality coupled to MS allows to study stereo selective chemical transformations at the microscale.
Lab Chip, 2017,17, 76-81
https://doi.org/10.1039/C6LC01217E
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Microfluidic centrifugation assisted precipitation based DNA quantification
A microfluidic centrifugation assisted precipitation method for rapid DNA visualization and quantification.
Lab Chip, 2019,19, 1657-1664
https://doi.org/10.1039/C9LC00196D
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High-throughput single-particle detections using a dual-height-channel-integrated pore
We report a proof-of-principle demonstration of particle concentration to achieve high-throughput resistive pulse detections of bacteria using a microfluidic-channel-integrated micropore.
Lab Chip, 2019,19, 1352-1358
https://doi.org/10.1039/C8LC01371C
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Multiparameter antibiotic resistance detection based on hydrodynamic trapping of individual E. coli
We present a single-bacteria hydrodynamic trapping platform to detect antibiotic susceptibility and resistance by simultaneously monitoring motility and morphology of individual E. coli.
Lab Chip, 2019,19, 1417-1426
https://doi.org/10.1039/C8LC01397G
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Overcoming transport limitations in miniaturized electrophoretic delivery devices
Combining experimental and theoretical approach, we demonstrate practical solutions to limiting currents in capillary-based electrophoretic delivery devices.
Lab Chip, 2019,19, 1427-1435
https://doi.org/10.1039/C9LC00038K
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Label-free separation of leukocyte subpopulations using high throughput multiplex acoustophoresis
Implementing a new designed cooling system for rigorous temperature control and minimal acoustic energy losses allows high-throughput multiplex acoustophoresis.
Lab Chip, 2019,19, 1406-1416
https://doi.org/10.1039/C9LC00181F
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Development of a multicellular pancreatic tumor microenvironment system using patient-derived tumor cells
The development of drugs to treat cancer is hampered by the inefficiency of translating pre-clinical in vitro monoculture and mouse studies into clinical benefit.
Lab Chip, 2019,19, 1193-1204
https://doi.org/10.1039/C8LC00755A
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Array based real-time measurement of fluid viscosities and mass-densities to monitor biological filament formation
A membrane-based resonator detecting filament formation of biological samples in a label- and functionalization-free manner.
Lab Chip, 2019,19, 1305-1314
https://doi.org/10.1039/C8LC01343H
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Grooved step emulsification systems optimize the throughput of passive generation of monodisperse emulsions
A novel step emulsifier allows high throughput production of monodisperse emulsions. Additionally, different modes of droplet production are investigated.
Lab Chip, 2019,19, 1183-1192
https://doi.org/10.1039/C8LC01096J
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Inertial focusing with sub-micron resolution for separation of bacteria
Inertial focusing in curved channels is demonstrated for particles between 0.5 and 2.0 μm in diameter; a range of biological relevance since it comprises a multitude of bacteria and organelles of eukaryotic cells.
Lab Chip, 2019,19, 1257-1266
https://doi.org/10.1039/C9LC00080A
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Lipid coated liquid crystal droplets for the on-chip detection of antimicrobial peptides
Lipid coated liquid crystal droplets have been trapped in a novel trap structure for the on-chip detection of a model antimicrobial peptide – Smp43, an α-helical peptide from Scorpion Venom.
Lab Chip, 2019,19, 1082-1089
https://doi.org/10.1039/C8LC01291A
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Gradient in the electric field for particle position detection in microfluidic channels
In this work a new method to track particles in microfluidic channels is presented.
Lab Chip, 2019,19, 1054-1059
https://doi.org/10.1039/C8LC01333K
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Formation of precisely composed cancer cell clusters using a cell assembly generator (CAGE) for studying paracrine signaling at single-cell resolution
Generation of exact cell clusters in the CAGE chip allows for paracrine signaling studies in models of specific tissue niches.
Lab Chip, 2019,19, 1071-1081
https://doi.org/10.1039/C8LC01153B
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Modular soft robotic microdevices for dexterous biomanipulation
We present a methodology for building biologically inspired, soft microelectromechanical systems (MEMS) devices.
Lab Chip, 2019,19, 778-788
https://doi.org/10.1039/C8LC01200H
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A microfluidic platform for the characterisation of membrane active antimicrobials
We quantify the membranolytic activity of antimicrobial peptides on biomimetic lipid vesicles in a multilayer microfluidic total analysis system.
Lab Chip, 2019,19, 837-844
https://doi.org/10.1039/C8LC00932E
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Latchable microfluidic valve arrays based on shape memory polymer actuators
Latchable microfluidic valve arrays taking advantage of the shape memory polymer's multiple stable shapes and large change in stiffness for a small temperature variation.
Lab Chip, 2019,19, 608-617
https://doi.org/10.1039/C8LC01024B
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Analysis and simulation of multiphase hydrodynamics in capillary microseparators
The capillary microseparator is an important microfluidic device for achieving the inline separation of biphasic segmented flows.
Lab Chip, 2019,19, 706-715
https://doi.org/10.1039/C8LC01296B
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Ultra-high capacity microfluidic trapping of giant vesicles for high-throughput membrane studies
A high-capacity microfluidic platform designed to capture tens of thousands of giant vesicles for high-throughput membrane analysis.
Lab Chip, 2019,19, 626-633
https://doi.org/10.1039/C8LC01275J
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Parahydrogen based NMR hyperpolarisation goes micro: an alveolus for small molecule chemosensing
We implemented continuous-flow SABRE NMR spectroscopy on a chip, unlocking low-volume chemosensing of strongly diluted analytes.
Lab Chip, 2019,19, 503-512
https://doi.org/10.1039/C8LC01259H
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Acoustophoretic focusing effects on particle synthesis and clogging in microreactors
An acoustophoretic microreactor to manage particles in flow and to control the material synthesis process.
Lab Chip, 2019,19, 316-327
https://doi.org/10.1039/C8LC00675J
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
A lung/liver-on-a-chip platform for acute and chronic toxicity studies
A lung/liver-on-a-chip platform with metabolic capability over 28 days: a fit-for-purpose microfluidic system for toxicity assessment of pulmonary toxicants.
Lab Chip, 2018,18, 3814-3829
https://doi.org/10.1039/C8LC01029C
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Correlative light and electron microscopy for complex cellular structures on PDMS substrates with coded micro-patterns
A correlative light and electron microscopy system that utilizes PDMS substrates with coded micro-patterns has been developed.
Lab Chip, 2018,18, 3840-3848
https://doi.org/10.1039/C8LC00703A
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Microfluidic bead encapsulation above 20 kHz with triggered drop formation
Bead-triggered breakup of a fluid jet into monodispersed droplets improves the throughput of bead-based droplet workflows, enabling the analysis of large populations and the detection of rare events.
Lab Chip, 2018,18, 3598-3605
https://doi.org/10.1039/C8LC00514A
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Screening of nutritional and genetic anemias using elastic light scattering
Elastic light scattering and machine learning accurately discriminates between healthy children, those with iron deficiency, and those with thalassemia minor.
Lab Chip, 2018,18, 3263-3271
https://doi.org/10.1039/C8LC00377G
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
An automated in vitro motility assay for high-throughput studies of molecular motors
Molecular motors, essential to force-generation and cargo transport within cells, are invaluable tools for powering nanobiotechnological lab-on-a-chip devices.
Lab Chip, 2018,18, 3196-3206
https://doi.org/10.1039/C8LC00547H
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Millifluidic culture improves human midbrain organoid vitality and differentiation
The use of millifluidics technology for human midbrain organoid cultures reduces central cell death and increases dopaminergic neuron differentiation.
Lab Chip, 2018,18, 3172-3183
https://doi.org/10.1039/C8LC00206A
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
3D microfluidic ex vivo culture of organotypic tumor spheroids to model immune checkpoint blockade
Microfluidic culture has the potential to revolutionize cancer diagnosis and therapy.
Lab Chip, 2018,18, 3129-3143
https://doi.org/10.1039/C8LC00322J
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Effect of exercise on the plasma vesicular proteome: a methodological study comparing acoustic trapping and centrifugation
Improved reproducibility in seed particle mediated acoustic trapping of submicron particles enables clinical biomarker studies in extracellular vesicles.
Lab Chip, 2018,18, 3101-3111
https://doi.org/10.1039/C8LC00686E
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Multi-parametric cell profiling with a CMOS quad-modality cellular interfacing array for label-free fully automated drug screening
A 1024-pixel CMOS quad-modality cellular interfacing array that enables multi-parametric cell profiling and holistic cellular characterization for drug development.
Lab Chip, 2018,18, 3037-3050
https://doi.org/10.1039/C8LC00156A
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Quantitative phase microscopy of red blood cells during planar trapping and propulsion
Here, we have combined quantitative phase microscopy and waveguide trapping techniques to study changes in RBC morphology during planar trapping and transportation.
Lab Chip, 2018,18, 3025-3036
https://doi.org/10.1039/C8LC00356D
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
High-throughput single-molecule bioassay using micro-reactor arrays with a concentration gradient of target molecules
We developed micro-reactor arrays with a concentration gradient of target molecules for high-throughput single-molecule bioassay.
Lab Chip, 2018,18, 2849-2853
https://doi.org/10.1039/C8LC00535D
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Continuous removal of small nonviable suspended mammalian cells and debris from bioreactors using inertial microfluidics
We introduce a new application of spiral inertial microfluidics for removing small nonviable cells from a mammalian suspension culture.
Lab Chip, 2018,18, 2826-2837
https://doi.org/10.1039/C8LC00250A
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Monitoring real-time hormone release kinetics via high-content 3-D imaging of compensatory endocytosis
A novel technology for quantifying hormone secretion from tissues, with a single-cell resolution.
Lab Chip, 2018,18, 2838-2848
https://doi.org/10.1039/C8LC00417J
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Acoustic formation of multicellular tumor spheroids enabling on-chip functional and structural imaging
Combining a protein repellent coating and ultrasonic standing waves in microwells enables on-chip formation and confocal microscopy of multicellular tumor spheroids.
Lab Chip, 2018,18, 2466-2476
https://doi.org/10.1039/C8LC00537K
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Quantitative and multiplex microRNA assays from unprocessed cells in isolated nanoliter well arrays
This platform utilizes functionalized hydrogel posts contained within isolated nanoliter well reactors for quantitative and multiplex microRNA assays directly from unprocessed cell samples without needing prior nucleic acid extraction.
Lab Chip, 2018,18, 2410-2424
https://doi.org/10.1039/C8LC00498F
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Sequencing of human genomes extracted from single cancer cells isolated in a valveless microfluidic device
Whole genome sequencing of single cancer cells isolated and lysed in an injection-moulded valveless microfluidic device.
Lab Chip, 2018,18, 1891-1902
https://doi.org/10.1039/C8LC00169C
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
A universal platform for selection and high-resolution phenotypic screening of bacterial mutants using the nanowell slide
Dual selection, high-resolution phenotypic screening and genotypic analysis of single-derived bacterial nanocultures using a 672-nanowell slide.
Lab Chip, 2018,18, 1767-1777
https://doi.org/10.1039/C8LC00190A
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Enhanced ion transport using geometrically structured charge selective interfaces
A microfluidic platform containing charged hydrogels is used to investigate the effect of geometry on charge transport in electrodialysis applications.
Lab Chip, 2018,18, 1652-1660
https://doi.org/10.1039/C7LC01220A
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
A biomimetic microfluidic model to study signalling between endothelial and vascular smooth muscle cells under hemodynamic conditions
Cell signalling and mechanics influence vascular pathophysiology and there is an increasing demand for in vitro model systems that enable examination of signalling between vascular cells under hemodynamic conditions.
Lab Chip, 2018,18, 1607-1620
https://doi.org/10.1039/C8LC00286J
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Roll-to-roll fabrication of integrated PDMS–paper microfluidics for nucleic acid amplification
High-volume roll-to-roll manufacturing of PDMS–paper microfluidics.
Lab Chip, 2018,18, 1552-1559
https://doi.org/10.1039/C8LC00269J
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Multiparameter cell-tracking intrinsic cytometry for single-cell characterization
We introduce a multiparameter intrinsic cytometry approach for single-cell characterization that combines ≥2 label-free measurement techniques onto the same platform.
Lab Chip, 2018,18, 1430-1439
https://doi.org/10.1039/C8LC00240A
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Electrically controlled mass transport into microfluidic droplets from nanodroplet carriers with application in controlled nanoparticle flow synthesis
Infuse chemical into microdroplets from nanodroplet carriers with rates and dosages controlled by electrical fields, and applications in nanoparticle synthesis.
Lab Chip, 2018,18, 1330-1340
https://doi.org/10.1039/C8LC00114F
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Inertial manipulation of bubbles in rectangular microfluidic channels
The position of bubbles in rectangular microchannels can be controlled by tuning the balance of forces acting on them.
Lab Chip, 2018,18, 1035-1046
https://doi.org/10.1039/C7LC01283G
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Microfluidic label-free selection of mesenchymal stem cell subpopulation during culture expansion extends the chondrogenic potential in vitro
A microfluidic cell sorting based selective culture expansion method for mesenchymal stem cell improves cell yield and chondrogenic potential.
Lab Chip, 2018,18, 878-889
https://doi.org/10.1039/C7LC01005B
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Closed-loop feedback control for microfluidic systems through automated capacitive fluid height sensing
Precise fluid height sensing in open-channel microfluidics has long been a desirable feature for a wide range of applications.
Lab Chip, 2018,18, 902-914
https://doi.org/10.1039/C7LC01223C
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Flocculation on a chip: a novel screening approach to determine floc growth rates and select flocculating agents
A novel microfluidic flocculation screening tool to efficiently compare flocculating agents and rapidly find the best flocculating condition using in situ detection of flocculation growth rates.
Lab Chip, 2018,18, 585-594
https://doi.org/10.1039/C7LC00793K
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
On-chip functional neuroimaging with mechanical stimulation in Caenorhabditis elegans larvae for studying development and neural circuits
New designs of microfluidic devices can facilitate recording of C. elegans larvae neuronal responses to precise mechanical stimuli, which reveal new understanding of development of mechanosensory neurons and circuits.
Lab Chip, 2018,18, 601-609
https://doi.org/10.1039/C7LC01201B
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Acoustically modulated biomechanical stimulation for human cartilage tissue engineering
The biomechanical environment in an acoustofluidic bioreactor is modified by controlling the acoustic driving conditions to promote human cartilage generation.
Lab Chip, 2018,18, 473-485
https://doi.org/10.1039/C7LC01195D
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
A deep conical agarose microwell array for adhesion independent three-dimensional cell culture and dynamic volume measurement
Miniaturised conical measures for cell aggregates.
Lab Chip, 2018,18, 179-189
https://doi.org/10.1039/C7LC00832E
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
On-chip label-free protein analysis with downstream electrodes for direct removal of electrolysis products
Single-layer lithography microfluidic devices for applying high and stable electric fields on chip.
Lab Chip, 2018,18, 162-170
https://doi.org/10.1039/C7LC00797C
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
An ultra-small, multi-point, and multi-color photo-detection system with high sensitivity and high dynamic range
Fluorescence from four emission points is collimated by four lenses, split into four-color fluxes by four dichroic mirrors, and directly input into the image sensor.
Lab Chip, 2017,17, 4231-4242
https://doi.org/10.1039/C7LC01070B
About this collection
Please see below for recent Open Access papers published in Lab on a Chip.