Microneedle-based sensors for medical diagnosis
The field of microneedle sensors is reviewed discussing current trends and future applications.
Carbon dots: surface engineering and applications
Surface engineering of carbon dots and their applications in targeting sensing, accurate drug delivery and high resolution bioimaging are highlighted.
Pluripotent stem cell derived hepatocytes: using materials to define cellular differentiation and tissue engineering
Pluripotent stem cell derived liver cells (hepatocytes) represent a promising alternative to primary tissue for biological and clinical applications.
Graphene scaffolds in progressive nanotechnology/stem cell-based tissue engineering of the nervous system
Graphene scaffolds are highly promising candidates in the versatile physicochemical stimulated proliferation/differentiation of neural stem cells required in future regenerative nanomedicine.
Micro/nanostructured surfaces for self-powered and multifunctional electronic skins
We introduce recent advances in the design of bioinspired micro/nanostructures and 2D/3D structures for the enhancement of energy harvesting and multifunctional sensing properties of flexible electronic skins.
Nanostructure-based surface-enhanced Raman scattering biosensors for nucleic acids and proteins
Nanostructure-based SERS platforms have been developed for nucleic acid and protein detection ranging from label-free, labeled and multiplex analyses.
Biomolecular strategies to modulate the macrophage response to implanted materials
Materials engineered to display immunomodulatory molecules including adhesion ligands, cytokines, and self-proteins, target receptors on immune cells to modulate their response to biomaterial implants.
PEG based anti-cancer drug conjugated prodrug micelles for the delivery of anti-cancer agents
Development of polymer prodrug conjugates has evolved recently in the nano-medicine field for cancer diagnosis and treatment. This review focuses on the development of different types of PEG based polymer drug conjugates used for the delivery of anti-cancer agents.
Cellular modulation by the elasticity of biomaterials
The elasticity of the extracellular matrix has been increasingly recognized as a dominating factor of cell fate and activities. This review provides an overview of the general principles and recent advances in the field of matrix elasticity-dependent regulation of a variety of cellular activities and functions, the underlying biomechanical and molecular mechanisms, as well as the pathophysiological implications.
Enhanced user-control of small molecule drug release from a poly(ethylene glycol) hydrogel via azobenzene/cyclodextrin complex tethers
Photoresponsive azobenzene–cyclodextrin guest–host chemistry can be used to control the release rate of a small peptide from a PEG hydrogel with light.
A facile and one-step ethanol-thermal synthesis of MoS2 quantum dots for two-photon fluorescence imaging
MoS2 quantum dots with two-photon fluorescence features are synthesized through a one-step solvothermal approach and successfully used for cellular bioimaging.
Carbon dots as a trackable drug delivery carrier for localized cancer therapy in vivo
Green carbon dots with a carboxyl-rich surface were employed as a selective nanocarrier for fluorescent traceable and pH-sensitive Doxorubicin delivery in localized cancer treatment.
Preparation of graphene nano-sheet bonded PDA/MOF microcapsules with immobilized glucose oxidase as a mimetic multi-enzyme system for electrochemical sensing of glucose
A novel amperometric biosensor for glucose detection was fabricated based on a mimetic multi-enzyme system by combing mimetic enzymes (metal–organic frameworks, MOFs) and glucose oxidase (GOx).
Silica-assisted incorporation of polydopamine into the framework of porous nanocarriers by a facile one-pot synthesis
Mussel-inspired polydopamine (PDA), with its advanced bio-adhesive properties, has shown great potential in drug delivery based on host–guest interaction.
Multicolour fluorescent carbon nanoparticle probes for live cell imaging and dual palladium and mercury sensors
Cytocompatible carbon nanoparticles (CNPs) having high quantum yield and multicolour bioimaging properties were synthesized and employed as sensitive, selective and rapid dual sensor for Pd2+ and Hg2+.
Reduction-responsive fluorescence off–on BODIPY–camptothecin conjugates for self-reporting drug release
A reduction-responsive fluorescence off–on theranostic prodrug with self-reporting drug release was constructed based on boron dipyrromethene (BODIPY) and therapeutic drug camptothecin (CPT) with a long flexible disulfide linker.
Gelatin methacrylate/carboxybetaine methacrylate hydrogels with tunable crosslinking for controlled drug release
In this work, methacrylated gelatin (GelMA) based hydrogels were fabricated with carboxybetaine methacrylate (CBMA) to manipulate the properties of the gelatin-based hydrogels, since CBMA is a much smaller compound compared to gelatin.
A switchable peroxidase mimic derived from the reversible co-assembly of cytochrome c and carbon dots
We describe a straightforward tactic to boost the inherently low peroxidase-like activity of the heme-protein equine cytochrome c following its electrostatic assembly onto the carbon nanodot surface.
Bio-inspired smart hydrogel with temperature-dependent properties and enhanced cell attachment
Stimuli-responsive smart hydrogels have been exploited for various applications, including as biomaterials with environment-dependent changes in hydrophobicity, stiffness or volume.
Biomimetic gelatin methacrylamide hydrogel scaffolds for bone tissue engineering
The biomimetic GelMA scaffolds which have highly porous, interconnected macropores, and rough surface could promote ADSC to differentiate into osteoblasts and bone formation.
Novel magneto-responsive membrane for remote control switchable molecular sieving
Magneto-responsive separation membrane: reversible change of molecule sieving through pore-confined polymeric hydrogel network by remote control of immobilized “nano heaters” with alternating magnetic field.
A toolbox for controlling the properties and functionalisation of hydrazone-based supramolecular hydrogels
In situ multicomponent hydrogelator formation enables straightforward chemical functionalisation of supramolecular hydrogels.
A self-healing, re-moldable and biocompatible crosslinked polysiloxane elastomer
The self-healable polysiloxane elastomers cross-linked with DA bonds show high healing efficiency, good mechanical properties and good biocompatibility.
Electrospun polyurethane/keratin/AgNP biocomposite mats for biocompatible and antibacterial wound dressings
Keratin based biomaterials have emerged as potential candidates for various biomedical and biotechnological applications due to their intrinsic biocompatibility, biodegradability, mechanical durability, and natural abundance.
High biocompatibility and improved osteogenic potential of amorphous calcium carbonate/vaterite
Metastable amorphous calcium carbonate (ACC), formed as a precursor of crystalline carbonated apatite/hydroxyapatite in human bone, can be stabilized by inorganic polyphosphate. The resulting CaCO3/polyP, containing small amounts of vaterite, has osteogenic potential and potential application as a scaffold material for bone implants.
Green preparation of nitrogen-doped carbon dots derived from silkworm chrysalis for cell imaging
Carbon dots (CDs) with a high quantum yield of 46% are prepared using a green one-pot approach under microwaves with silkworm chrysalis which has been used for cell imaging.
Direct exfoliation of graphite into graphene in aqueous solutions of amphiphilic peptides
Peptide-mediated solution phase graphene exfoliation.
Prussian blue nanoparticles encapsulated inside a metal–organic framework via in situ growth as promising peroxidase mimetics for enzyme inhibitor screening
Metal–organic framework-based peroxidase mimetics for enzyme-inhibitor screening.
Protein-modified hollow copper sulfide nanoparticles carrying indocyanine green for photothermal and photodynamic therapy
Protein-modified hollow copper sulfide nanoparticles carrying indocyanine green (ICG) facilitate combined therapeutic effects including photothermal therapy of CuS nanocarriers and cytotoxic effects of photodynamic and photothermal therapy by ICG.
Dual-targeted activatable photosensitizers with aggregation-induced emission (AIE) characteristics for image-guided photodynamic cancer cell ablation
The currently available photosensitizers (PSs) for photodynamic therapy (PDT) can easily lead to undesirable normal cell death due to their intrinsic photo-toxicity and lack of selectivity for cancer cells.
About this collection
This web collection features the top 30 most downloaded articles published in Journal of Materials Chemistry B in 2016.
Congratulations to all of the authors whose articles have been featured!