Themed collection Journal of Materials Chemistry B Emerging Investigators

29 items
Profile

Contributors to the Emerging Investigators 2021 issue

Journal of Materials Chemistry B profiles contributors to the Emerging Investigators 2021 issue.

Graphical abstract: Contributors to the Emerging Investigators 2021 issue
Open Access Perspective

RNA BioMolecular Electronics: towards new tools for biophysics and biomedicine

Nanoscience has enabled the electrical study of individual biomolecules. This perspective presents the nascent field of RNA BioMolecular Electronics, overviewing the main developments and exploring recent and future potential applications.

Graphical abstract: RNA BioMolecular Electronics: towards new tools for biophysics and biomedicine
Perspective

Nanoparticle-mediated surfactant therapy in patients with severe COVID-19: a perspective

Nanoparticle-mediated surfactant therapy in patients with severe COVID-19.

Graphical abstract: Nanoparticle-mediated surfactant therapy in patients with severe COVID-19: a perspective
From the themed collection: Journal of Materials Chemistry B HOT Papers
Review Article

Multifunctional high-Z nanoradiosensitizers for multimodal synergistic cancer therapy

This review focuses on recent advances in multifunctional high-Z nanomaterials for radiotherapeutic-based multimodal synergistic cancer therapy.

Graphical abstract: Multifunctional high-Z nanoradiosensitizers for multimodal synergistic cancer therapy
Review Article

Electroactive nanomaterials in the peripheral nerve regeneration

Severe peripheral nerve injuries are threatening the life quality of human beings.

Graphical abstract: Electroactive nanomaterials in the peripheral nerve regeneration
Review Article

Manganese oxide nanomaterials boost cancer immunotherapy

This review summarized the recent advances of manganese oxide nanomaterials for cancer immunotherapy, covering adjusting an immunosuppressive tumor microenvironment, inducing immunogenic cell death, immunoadjuvants for nanovaccines and so on.

Graphical abstract: Manganese oxide nanomaterials boost cancer immunotherapy
Review Article

Smart near infrared-responsive nanocomposite hydrogels for therapeutics and diagnostics

This review article highlights recent research progress on the NIR-responsive nanocomposite hydrogels, focusing on their preparation, properties, applications and future prospectus.

Graphical abstract: Smart near infrared-responsive nanocomposite hydrogels for therapeutics and diagnostics
Review Article

Superoxide dismutase nanozymes: an emerging star for anti-oxidation

This review summarizes catalytic mechanisms, regulatory factors, measurement methods and various applications of SOD-like nanozymes, as well as proposes the current challenges and prospects in the development of SOD-like nanozymes.

Graphical abstract: Superoxide dismutase nanozymes: an emerging star for anti-oxidation
From the themed collection: Journal of Materials Chemistry B HOT Papers
Review Article

Recent advances in the development of nitric oxide-releasing biomaterials and their application potentials in chronic wound healing

This paper reviews the recent progress in nitric oxide (NO) donors, biomaterial vectors, biomaterial-based NO delivery systems and NO synthetic enzyme mimics, and emphasizes the application potentials of NO releasing biomaterials in chronic wound healing.

Graphical abstract: Recent advances in the development of nitric oxide-releasing biomaterials and their application potentials in chronic wound healing
Review Article

Recent near-infrared light-activated nanomedicine toward precision cancer therapy

This review summarizes the recent developments in different NIR-based nanomedicine for cancer therapy.

Graphical abstract: Recent near-infrared light-activated nanomedicine toward precision cancer therapy
Review Article

Bringing naturally-occurring saturated fatty acids into biomedical research

This review introduces naturally-occurring saturated fatty acids (NSFAs) and their biomedical applications, including controlled drug release, targeted drug delivery, cancer therapy, antibacterial treatment, and tissue engineering.

Graphical abstract: Bringing naturally-occurring saturated fatty acids into biomedical research
From the themed collection: Journal of Materials Chemistry B HOT Papers
Review Article

Biomacromolecule-based photo-thermal agents for tumor treatment

Recent advances in the design, fabrication, and applications of biomacromolecule-based photo-thermal agents are summarized. Cell membranes, proteins, nucleotides and polysaccharides are involved. Perspectives and challenges are also presented.

Graphical abstract: Biomacromolecule-based photo-thermal agents for tumor treatment
Review Article

DNA-based ribonuclease detection assays

This review describes some of the recent developments in DNA-based techniques for ribonuclease detection and discusses methodologies, assay metrics, screening of ribonuclease inhibitors, and future potential.

Graphical abstract: DNA-based ribonuclease detection assays
Open Access Review Article

Polysaccharide nanoparticles: from fabrication to applications

The present review highlights the developments in polysaccharide nanoparticles with a particular focus on applications in biomedicine, cosmetics and food.

Graphical abstract: Polysaccharide nanoparticles: from fabrication to applications
Communication

Spatially heterogeneous epidermal growth factor release from microporous annealed particle (MAP) hydrogel for improved wound closure

We present lyophilized heparin microgels which can be directly rehydrated with epidermal growth factor and mixed with PEG microgels to form heterogenous MAP scaffolds. These EGF-releasing MAP scaffolds promote accelerated dermal wound healing.

Graphical abstract: Spatially heterogeneous epidermal growth factor release from microporous annealed particle (MAP) hydrogel for improved wound closure
Communication

Kinetic control of chirality and circularly polarized luminescence in G-quartet materials

Here, we found that the handedness and CPL properties of G-quartet materials highly depends on its formation kinetics.

Graphical abstract: Kinetic control of chirality and circularly polarized luminescence in G-quartet materials
Paper

pH-Sensitive branched β-glucan-modified liposomes for activation of antigen presenting cells and induction of antitumor immunity

pH-Sensitive branched β-glucan-modified liposomes promote antigen uptake and activation of dendritic cells in vitro, inducing anti-tumor immune responses in vivo.

Graphical abstract: pH-Sensitive branched β-glucan-modified liposomes for activation of antigen presenting cells and induction of antitumor immunity
Paper

Engineering mesoporous silica nanoparticles towards oral delivery of vancomycin

Vancomycin (Van) is an antibiotic of choice for many drug resistant infections but cannot be given orally due to its poor permeability. Encapsulation of Vancomycin within MSNs improved its gastrointestinal permeation and provided controlled release.

Graphical abstract: Engineering mesoporous silica nanoparticles towards oral delivery of vancomycin
Paper

Delivery of a system xc inhibitor by a redox-responsive levodopa prodrug nanoassembly for combination ferrotherapy

A ferroptosis nano-prodrug (SSZ–Fe2+@DSSD) that can generate intercellular ROS and inhibit the system xc-GSH-GPX4 pathway to enhance the cancer ferrotherapy.

Graphical abstract: Delivery of a system xc− inhibitor by a redox-responsive levodopa prodrug nanoassembly for combination ferrotherapy
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

A ‘smart’ aptamer-functionalized continuous label-free cell catch–transport–release system

A ‘smart’ aptamer-functionalized catch–transport–release system was developed with facile fabrication for continuous, selective, high-throughput label-free cell sorting.

Graphical abstract: A ‘smart’ aptamer-functionalized continuous label-free cell catch–transport–release system
Paper

Molecule-specific vibration-based chiral differentiation of Raman spectra using cysteine modified gold nanoparticles: the cases of tyrosine and phenylalanine

The chirality of amino acids plays a key role in many biochemical processes, with the development of spectroscopic analysis methods for the chiral differentiation of amino acids being significant.

Graphical abstract: Molecule-specific vibration-based chiral differentiation of Raman spectra using cysteine modified gold nanoparticles: the cases of tyrosine and phenylalanine
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Hydrogel nanoparticle degradation influences the activation and survival of primary macrophages

The effect of nanoparticle (NP) internalization and subsequent degradation rate on cell lifespan has emerged as an important consideration for nanomedicine design, as macrophages and other phagocytes are primary clearance mechanisms of administered NP formulations.

Graphical abstract: Hydrogel nanoparticle degradation influences the activation and survival of primary macrophages
Paper

3D printed architected conducting polymer hydrogels

Rationally designed, 3D-printed architectures can effectively decouple the mechanical and electrical properties of conducting polymer hydrogels.

Graphical abstract: 3D printed architected conducting polymer hydrogels
Paper

Carambola-like Bi2Te3 superstructures with enhanced photoabsorption for highly efficient photothermal therapy in the second near-infrared biowindow

Carambola-like Bi2Te3 superstructures endow Bi2Te3@PEG with enhanced photoabsorption in the near-infrared region, making them a promising tool for highly efficient photothermal therapy in the second near-infrared biowindow.

Graphical abstract: Carambola-like Bi2Te3 superstructures with enhanced photoabsorption for highly efficient photothermal therapy in the second near-infrared biowindow
Paper

Synthesis-temperature-regulated multi-enzyme-mimicking activities of ceria nanozymes

Facile-regulation of the multi-enzyme-mimicking activities and effective guidelines from radar analysis established here advance the further biomedical applications of ceria-based nanozymes.

Graphical abstract: Synthesis-temperature-regulated multi-enzyme-mimicking activities of ceria nanozymes
Paper

Diatom-inspired 2D nitric oxide releasing anti-infective porous nanofrustules

This paper describes the development and antibacterial activity of a 2D nitric oxide releasing nanocomposite with a mesoporous structure inspired by nature's diatoms.

Graphical abstract: Diatom-inspired 2D nitric oxide releasing anti-infective porous nanofrustules
Paper

Engineering Cu2−xS-conjugated upconverting nanocomposites for NIR-II light-induced enhanced chemodynamic/photothermal therapy of cancer

Cu2−xS-conjugated upconverting nanocomposites with an outstanding photothermal killing effect and a PT-enhanced CDT effect for NIR-II light-induced enhanced chemodynamic/photothermal therapy of cancer.

Graphical abstract: Engineering Cu2−xS-conjugated upconverting nanocomposites for NIR-II light-induced enhanced chemodynamic/photothermal therapy of cancer
Paper

Hyaluronic acid drives mesenchymal stromal cell-derived extracellular matrix assembly by promoting fibronectin fibrillogenesis

Hyaluronic acid (HA) is present at sites of ongoing fibronectin fibrillogenesis (fibrillar adhesions) and necessary for efficient fibronectin fibrillogenesis. As a result, fibronectin deposition can be enhanced by exogenous HA.

Graphical abstract: Hyaluronic acid drives mesenchymal stromal cell-derived extracellular matrix assembly by promoting fibronectin fibrillogenesis
Paper

Tannic acid-inspired, self-healing, and dual stimuli responsive dynamic hydrogel with potent antibacterial and anti-oxidative properties

Tannic acid cross-linked dynamic hydrogels hybridized with tannic acid reduced silver nanoparticles shows multi-functional properties including dual stimuli responsive drug release, anti-bacterial and anti-reactive oxygen species abilities.

Graphical abstract: Tannic acid-inspired, self-healing, and dual stimuli responsive dynamic hydrogel with potent antibacterial and anti-oxidative properties
From the themed collection: Journal of Materials Chemistry B HOT Papers
29 items

About this collection

Journal of Materials Chemistry B is proud to present this themed issue highlighting 2021’s rising stars of materials chemistry research. This issue gathers the very best work from materials chemists in the early stages of their independent career.

Each contributor was recommended by experts in their fields as carrying out work with the potential to influence future directions in materials chemistry with applications in biology and medicine. We would like to congratulate all the excellent researchers featured.

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