Themed collection 2019 Journal of Materials Chemistry B Most Popular Articles

Dual acid-responsive bola-type supramolecular vesicles have been successfully constructed for efficient intracellular anticancer drug delivery and controlled release.

Hydrogen therapy is an emerging and promising strategy for the treatment of inflammation-related diseases owing to the excellent bio-safety of hydrogen molecules (H₂), but is facing a challenge that the H₂ concentration at the local disease site is hardly accumulated because of its high diffusibility and low solubility, limiting the efficacy of hydrogen therapy.

Tough and self-adhesive zwitterionic hydrogels with ionic conductivity have been prepared, showing high and linear strain sensitivity for detecting human motions.

A novel Sild hapten was successfully synthesized and a sensitive anti-Sild mAb was produced based on this hapten. The immunochromatographic assay (ICA) allowed qualitative and quantitative detection of Sild and its analogues in food samples within 15 min. The ICA was successfully applied to real samples and showed a good correlation with ic-ELISA.

TR-OCl exhibits ultra-high sensitivity towards HOCl with a 7000-fold enhancement in the fluorescence ratio (I₅₈₉/I₄₇₇) and a detection limit of 1.29 nM, which is one of the highest recorded so far.

The rapidly expanding fields of bioelectronics, and biological interfaces with sensors and stimulators, are placing an increasing demand on candidate materials to serve as robust surfaces that are both biocompatible, stable and electroconductive.

Bifunctional MIL-53(Fe) with PPi-mediated peroxidase-like activity and oxidation-stimulated fluorescence switching was explored for ALP sensing.

A flexible and wearable sensor is prepared to monitor human motions such as joint motion, speaking, breathing, and slight blood pulsation.

MgO nanoparticles are synthesized using water, ethanol and aqueous CTAB solution. The nanoparticles synthesized in ethanol exhibited smallest size, maximum reactive oxygen species generation and maximum antibacterial ability, and low haemolysis.

FA–COS–TGA–GNRs–DOX have been successfully designed as a drug delivery system for chemo-photothermal combination therapy.

The nanoassemblies of Dex_6k–BSA–PTX and the pH-responsive drug release for anti-tumor applications in vivo.

We demonstrate a strong enhancement of the antimicrobial action of vancomycin encapsulated in shellac nanocarriers with cationic surface functionality which concentrate on the microbial cell membranes.

Cu-NP-embedded hydrogel (BACA/Cu NPs/Gel-MA hydrogel) produces ROS for photothermal therapy, killing bacteria, and promoting wound healing.

Controlling the degree of methacryloyl substitution on chondroitin sulfate allows for tunable drug release kinetics.

Zwitterionic hydrogels, as highly hydrated and soft materials, have been considered as promising materials for wound dressing, due to their unique antifouling and mechanical properties.

This work investigates neocartilage formation in bovine and porcine gelatin methacryloyl-based hydrogels photocrosslinked using ultraviolet or visible light photoinitiator systems.

A series of polymer micelles with a perfluorocarbon (PFC) core to carry both PS and O₂ to tumor sites was prepared. These new PFC formulation not only improved the production of ¹O₂ and enhanced the PDT efficiency, but also significantly reduced cell toxicity compared with the one without a perfluoro unit.

A NIR ratiometric fluorescent probe based on cyanine dye was developed for detecting and intracellular imaging of ALP activity with high sensitivity.

Pd nanoparticle-decorated graphitic C₃N₄ nanosheets with peroxidase mimicking and ON–OFF fluorescence for the naked-eye and fluorescent dual-readout detection of glucose.

Three near-infrared ratiometric fluorescent probes with different pK_a values were synthesized to achieve sensitive ratiometric visualization of pH variations in lysosomes.