Profile: Emerging Investigators 2016: novel design strategies for new functional materials
Journal of Materials Chemistry B profiles contributors to the Emerging Investigators issue.
Nano-engineered electro-responsive drug delivery systems
Nano-engineering is exploited to address the slow drug release and low drug loading of electro-responsive drug delivery systems.
Micro/nanostructured surfaces for self-powered and multifunctional electronic skins
We introduce recent advances in the design of bioinspired micro/nanostructures and 2D/3D structures for the enhancement of energy harvesting and multifunctional sensing properties of flexible electronic skins.
In vitro electrochemical characterization of polydopamine melanin as a tissue stimulating electrode material
The properties of redox active polydopamine melanin (PDM) films as a coating material for tissue stimulation electrodes were evaluated.
Sensing a Bacillis anthracis biomarker with well-known OLED emitter EuTta3Phen
Dipicolinic acid (DPA) is a distinctive biomarker for bacterial spores. Here, we present the successful demonstration of dramatic Switch-OFF sensing of DPA using an easily synthesised Eu(III) phosphor applied primarily in light-emitting devices. The sensor shows excellent selectivites, and in the presence of water and phosphate is also demonstrated to be effective.
Fluorinated smart micelles as enzyme-responsive probes for 19F-magnetic resonance
Labeling smart PEG–dendron hybrids with fluorine-containing groups transform their micelles into enzyme-responsive probes for 19F-magnetic resonance.
Heparin-stabilised iron oxide for MR applications: a relaxometric study
Heparin stabilisation of Fe3O4 nanoparticles engenders exceptional stability, enhanced relaxation due to interparticle interactions, and prevention of protein-adsorption triggered thrombosis.
Evaluation of the direct effects of poly(dopamine) on the in vitro response of human osteoblastic cells
Functional poly(dopamine) coatings promise to become an efficient strategy to endow biomaterials with enhanced bioactive properties.
Silica core–shell particles for the dual delivery of gentamicin and rifamycin antibiotics
Increasing bacterial resistance calls for the simultaneous delivery of multiple antibiotics.
Controlling the ion release from mixed alkali bioactive glasses by varying modifier ionic radii and molar volume
Modifier ionic radius controls ion release from bioactive phospho-silicate glasses via silicate network compactness.
Bacterial viability on chemically modified silicon nanowire arrays
Multi-functional silicon nanowires (SiNWs) arrays: (I) nanostructure topography in the form of SiNWs, (II) covalent chemical modification with APTES and (III) incorporation of chlorhexidine digluconate.
Near-infrared triggered generation of reactive oxygen species from upconverting nanoparticles decorated with an organoiridium complex
We developed an upconverting nanoparticle capable of (up)converting near-infrared excitation light to UV to sensitize an organoiridium complex for the production of reactive oxygen species.
Boronic acid-modified poly(amidoamine) dendrimers as sugar-sensing materials in water
High-affinity carbohydrate receptors were developed by appending boronic acids to the surface of PAMAM dendrimers. These multivalent hosts were used to discriminate simple sugars in neat water using pattern recognition and optical spectroscopy techniques.
Microgels with tunable affinity-controlled protein release via desolvation of self-assembled peptide nanofibers
We demonstrate an approach to fabricate microgels from self-assembled peptide nanofibers via desolvation. Proteins can be co-desolvated with nanofibers to create protein-loaded microgels. Modifying nanofibers with a protein-binding ligand provides tunable affinity-controlled protein release.
Microfluidically fabricated pH-responsive anionic amphiphilic microgels for drug release
Novel amphiphilic microgels with hydrophobic and hydrophilic monomer units on the polymer chains were fabricated with an on-chip polymerisation methodology using a novel chip design.
Characterization and optimization of pH-responsive polymer nanoparticles for drug delivery to oral biofilms
Corona and core molecular weights of p(DMAEMA)-b-p(DMAEMA-co-BMA-co-PAA) block copolymer micelles can be tuned to enhance drug release in response to acidic milieus consistent with oral biofilms.
Glycosylated gold nanoparticle libraries for label-free multiplexed lectin biosensing
Glycosylated nanoparticle libraries are developed to enable ‘barcode’ sensing of lectins and toxins.
About this collection
Journal of Materials Chemistry B is proud to present this themed issue highlighting 2016’s rising stars of materials chemistry research. This issue gathers the very best work from materials chemists in the early stages of their independent career, with a special focus on novel design strategies for new functional materials.
Each contributor was recommended by our prestigious Editorial Board as carrying out work with the potential to influence future directions in materials chemistry. Congratulations to all of those who feature on their important work so far in the field of materials for biology and medicine.