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Themed collection Advances in Optical and Electrochemical Techniques for Biomedical Imaging

18 items
Open Access Editorial

Advances in optical and electrochemical techniques for biomedical imaging

Yi-Tao Long and Thomas J. Meade introduce the Chemical Science retrospective themed collection on advances in optical and electrochemical techniques for biomedical imaging.

Graphical abstract: Advances in optical and electrochemical techniques for biomedical imaging
Open Access Minireview

Surface-enhanced Raman spectroscopy: benefits, trade-offs and future developments

Surface-enhanced Raman spectroscopy (SERS) is a vibrational spectroscopy technique with sensitivity down to the single molecule level that provides fine molecular fingerprints, allowing for direct identification of target analytes.

Graphical abstract: Surface-enhanced Raman spectroscopy: benefits, trade-offs and future developments
Open Access Minireview

Dynamic contrast with reversibly photoswitchable fluorescent labels for imaging living cells

Interrogating living cells requires sensitive imaging of a large number of components in real time.

Graphical abstract: Dynamic contrast with reversibly photoswitchable fluorescent labels for imaging living cells
Open Access Minireview

Electrochemical imaging of cells and tissues

This minireview summarizes the recent achievements of electrochemical imaging platforms to map cellular functions in biological specimens using electrochemical scanning nano/micro-probe microscopy and 2D chips containing microelectrode arrays.

Graphical abstract: Electrochemical imaging of cells and tissues
Open Access Minireview

Recent advances in near-infrared II fluorophores for multifunctional biomedical imaging

A review of recent advances in near-infrared II fluorophores for multifunctional biomedical imaging.

Graphical abstract: Recent advances in near-infrared II fluorophores for multifunctional biomedical imaging
Open Access Edge Article

Near-infrared aggregation-induced enhanced electrochemiluminescence from tetraphenylethylene nanocrystals: a new generation of ECL emitters

Tetraphenylethylene nanocrystals as new ECL emitters with near-infrared aggregation-induced enhanced electrochemiluminescence exhibited high ECL efficiency and excellent biocompatibility.

Graphical abstract: Near-infrared aggregation-induced enhanced electrochemiluminescence from tetraphenylethylene nanocrystals: a new generation of ECL emitters
Open Access Edge Article

Spatiotemporal imaging of electrocatalytic activity on single 2D gold nanoplates via electrogenerated chemiluminescence microscopy

Spatiotemporal resolved electrocatalytic activity on single 2D gold nanoplates was imaged via electrogenerated chemiluminescence microscopy.

Graphical abstract: Spatiotemporal imaging of electrocatalytic activity on single 2D gold nanoplates via electrogenerated chemiluminescence microscopy
Open Access Edge Article

In situ visualization of ozone in the brains of mice with depression phenotypes by using a new near-infrared fluorescence probe

A near-infrared fluorescent probe was exploited to sensitively visualize ozone in the brains of mice with depression phenotypes in situ.

Graphical abstract: In situ visualization of ozone in the brains of mice with depression phenotypes by using a new near-infrared fluorescence probe
Open Access Edge Article

Rational design of a super-contrast NIR-II fluorophore affords high-performance NIR-II molecular imaging guided microsurgery

A super-contrast NIR-II fluorophore IR-BEMC6P with enhanced quantum yield is developed and the excretion mechanism is identified.

Graphical abstract: Rational design of a super-contrast NIR-II fluorophore affords high-performance NIR-II molecular imaging guided microsurgery
Open Access Edge Article

Machine learning material properties from the periodic table using convolutional neural networks

Convolutional neural networks directly learned chemical information from the periodic table to predict the enthalpy of formation and compound stability.

Graphical abstract: Machine learning material properties from the periodic table using convolutional neural networks
Open Access Edge Article

Dynamically imaging collision electrochemistry of single electrochemiluminescence nano-emitters

Dynamically imaging stochastic collision electrochemistry of single nanoparticles by electrochemiluminescence microscopy enables visualization of diverse collision behaviours.

Graphical abstract: Dynamically imaging collision electrochemistry of single electrochemiluminescence nano-emitters
Open Access Edge Article

Sonophore-enhanced nanoemulsions for optoacoustic imaging of cancer

Dark Quencher, IRDye QC1 in nanoemulsion form offers excellent optoacoustic performance, suitable for non-invasive pre-clinical optoacoustic imaging.

Graphical abstract: Sonophore-enhanced nanoemulsions for optoacoustic imaging of cancer
Open Access Edge Article

Electrochemical impedance spectroscopy of single Au nanorods

Monochromatic dark-field microscopy coupled with high-frequency potential modulation leads to non-faradaic electrochemical impedance spectroscopy of single Au nanorods.

Graphical abstract: Electrochemical impedance spectroscopy of single Au nanorods
Open Access Edge Article

Through tissue imaging of a live breast cancer tumour model using handheld surface enhanced spatially offset resonance Raman spectroscopy (SESORRS)

Detection of a live 3D tumour model through 15 mm of tissue using SESORRS.

Graphical abstract: Through tissue imaging of a live breast cancer tumour model using handheld surface enhanced spatially offset resonance Raman spectroscopy (SESORRS)
Open Access Edge Article

Rational design of a water-soluble NIR AIEgen, and its application in ultrafast wash-free cellular imaging and photodynamic cancer cell ablation

The first water-soluble NIR AIEgen was synthesized and used for ultrafast wash-free cellular imaging and photodynamic cancer cell ablation.

Graphical abstract: Rational design of a water-soluble NIR AIEgen, and its application in ultrafast wash-free cellular imaging and photodynamic cancer cell ablation
Open Access Edge Article

Diketopyrrolopyrrole-based semiconducting polymer nanoparticles for in vivo second near-infrared window imaging and image-guided tumor surgery

PDFT1032, a new semiconducting polymer possessing a favorable absorption peak (1032 nm) and outstanding biocompatibility, may be widely applicable in clinical imaging and the surgical treatment of malignancy.

Graphical abstract: Diketopyrrolopyrrole-based semiconducting polymer nanoparticles for in vivo second near-infrared window imaging and image-guided tumor surgery
Open Access Edge Article

Enantiomeric resolution and X-ray optical activity of a tricobalt extended metal atom chain

Enantiopure single crystals of extended metal atom chains display exceptionally large optical X-ray dichroisms at the Co K-edge.

Graphical abstract: Enantiomeric resolution and X-ray optical activity of a tricobalt extended metal atom chain
Open Access Edge Article

3D chemical imaging of the brain using quantitative IR spectro-microscopy

Here, we introduce a unique high-throughput infrared (IR) microscopy method that combines automated image correction and subsequent spectral data analysis for 3D-IR image reconstruction.

Graphical abstract: 3D chemical imaging of the brain using quantitative IR spectro-microscopy
18 items

About this collection

This retrospective themed collection, curated by Associate Editors Yi-Tao Long and Thomas J. Meade, highlights some outstanding work on optical and electrochemical techniques for biomedical imaging published in Chemical Science.

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