Advances in optical and electrochemical techniques for biomedical imaging
Yi-Tao Long and Thomas J. Meade introduce the Chemical Science retrospective themed collection on advances in optical and electrochemical techniques for biomedical imaging.
Surface-enhanced Raman spectroscopy: benefits, trade-offs and future developments
Surface-enhanced Raman spectroscopy (SERS) is a vibrational spectroscopy technique with sensitivity down to the single molecule level that provides fine molecular fingerprints, allowing for direct identification of target analytes.
Dynamic contrast with reversibly photoswitchable fluorescent labels for imaging living cells
Interrogating living cells requires sensitive imaging of a large number of components in real time.
Electrochemical imaging of cells and tissues
This minireview summarizes the recent achievements of electrochemical imaging platforms to map cellular functions in biological specimens using electrochemical scanning nano/micro-probe microscopy and 2D chips containing microelectrode arrays.
Recent advances in near-infrared II fluorophores for multifunctional biomedical imaging
A review of recent advances in near-infrared II fluorophores for multifunctional biomedical imaging.
Near-infrared aggregation-induced enhanced electrochemiluminescence from tetraphenylethylene nanocrystals: a new generation of ECL emitters
Tetraphenylethylene nanocrystals as new ECL emitters with near-infrared aggregation-induced enhanced electrochemiluminescence exhibited high ECL efficiency and excellent biocompatibility.
Spatiotemporal imaging of electrocatalytic activity on single 2D gold nanoplates via electrogenerated chemiluminescence microscopy
Spatiotemporal resolved electrocatalytic activity on single 2D gold nanoplates was imaged via electrogenerated chemiluminescence microscopy.
In situ visualization of ozone in the brains of mice with depression phenotypes by using a new near-infrared fluorescence probe
A near-infrared fluorescent probe was exploited to sensitively visualize ozone in the brains of mice with depression phenotypes in situ.
Rational design of a super-contrast NIR-II fluorophore affords high-performance NIR-II molecular imaging guided microsurgery
A super-contrast NIR-II fluorophore IR-BEMC6P with enhanced quantum yield is developed and the excretion mechanism is identified.
Machine learning material properties from the periodic table using convolutional neural networks
Convolutional neural networks directly learned chemical information from the periodic table to predict the enthalpy of formation and compound stability.
Dynamically imaging collision electrochemistry of single electrochemiluminescence nano-emitters
Dynamically imaging stochastic collision electrochemistry of single nanoparticles by electrochemiluminescence microscopy enables visualization of diverse collision behaviours.
Sonophore-enhanced nanoemulsions for optoacoustic imaging of cancer
Dark Quencher, IRDye QC1 in nanoemulsion form offers excellent optoacoustic performance, suitable for non-invasive pre-clinical optoacoustic imaging.
Electrochemical impedance spectroscopy of single Au nanorods
Monochromatic dark-field microscopy coupled with high-frequency potential modulation leads to non-faradaic electrochemical impedance spectroscopy of single Au nanorods.
Through tissue imaging of a live breast cancer tumour model using handheld surface enhanced spatially offset resonance Raman spectroscopy (SESORRS)
Detection of a live 3D tumour model through 15 mm of tissue using SESORRS.
Rational design of a water-soluble NIR AIEgen, and its application in ultrafast wash-free cellular imaging and photodynamic cancer cell ablation
The first water-soluble NIR AIEgen was synthesized and used for ultrafast wash-free cellular imaging and photodynamic cancer cell ablation.
Diketopyrrolopyrrole-based semiconducting polymer nanoparticles for in vivo second near-infrared window imaging and image-guided tumor surgery
PDFT1032, a new semiconducting polymer possessing a favorable absorption peak (1032 nm) and outstanding biocompatibility, may be widely applicable in clinical imaging and the surgical treatment of malignancy.
Enantiomeric resolution and X-ray optical activity of a tricobalt extended metal atom chain
Enantiopure single crystals of extended metal atom chains display exceptionally large optical X-ray dichroisms at the Co K-edge.
3D chemical imaging of the brain using quantitative IR spectro-microscopy
Here, we introduce a unique high-throughput infrared (IR) microscopy method that combines automated image correction and subsequent spectral data analysis for 3D-IR image reconstruction.
About this collection
This retrospective themed collection, curated by Associate Editors Yi-Tao Long and Thomas J. Meade, highlights some outstanding work on optical and electrochemical techniques for biomedical imaging published in Chemical Science.