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Themed collection Bioactive surfaces for hard tissue regeneration

28 items
Editorial

Bioactive surfaces for hard tissue regeneration

Welcome to this themed issue of RSC Advances on bioactive surfaces for hard tissue regeneration.

Graphical abstract: Bioactive surfaces for hard tissue regeneration
Review Article

Application of plasma electrolytic oxidation to bioactive surface formation on titanium and its alloys

A review of the literature concerning the surface modification of titanium by plasma electrochemical oxidation is presented.

Graphical abstract: Application of plasma electrolytic oxidation to bioactive surface formation on titanium and its alloys
Review Article

Bioactive ceramics: from bone grafts to tissue engineering

The pathway followed by bioactive ceramics from their early use as bone grafts until the present day, where they are widely investigated to obtain porous scaffolds for bone tissue engineering, is reviewed.

Graphical abstract: Bioactive ceramics: from bone grafts to tissue engineering
Review Article

Scaffolds for bone tissue engineering: role of surface patterning on osteoblast response

This review documents the plethora of biomaterials for bone tissue engineering applications in tandem with experimental and brief theoretical studies on cell responses on textured substrates.

Graphical abstract: Scaffolds for bone tissue engineering: role of surface patterning on osteoblast response
Review Article

Recent progress in the field of multicomponent bioactive nanostructured films

Multicomponent bioactive nanostructured films (MuBiNaFs) with an excellent combination of various properties were developed and deposited by sputtering of composite targets produced via the self-propagating high-temperature synthesis method.

Graphical abstract: Recent progress in the field of multicomponent bioactive nanostructured films
Review Article

Inorganic material surfaces made bioactive by immobilizing growth factors for hard tissue engineering

This review summarizes the methods for immobilization of growth factors on inorganic materials for hard tissue engineering.

Graphical abstract: Inorganic material surfaces made bioactive by immobilizing growth factors for hard tissue engineering
Review Article

Carbon nanostructures for hard tissue engineering

Utilizing carbon nanostructures as high-performance scaffold materials in hard tissue engineering is both promising and challenging.

Graphical abstract: Carbon nanostructures for hard tissue engineering
Communication

Synthesis and characterization of hydroxyapatite on hydrolyzed polyacrylonitrile nanofiber templates

Non-cytotoxic bioactive composite fibers were synthesized on electrospun nanofibers containing amine and carboxyl groups on the surface.

Graphical abstract: Synthesis and characterization of hydroxyapatite on hydrolyzed polyacrylonitrile nanofiber templates
Paper

BMP2-loaded nanoporous silica nanoparticles promote osteogenic differentiation of human mesenchymal stem cells

Nanoporous silica nanoparticles with immobilized BMP2 as depicted in the scheme effectively promote osteogenic differentiation of mesenchymal stem cells.

Graphical abstract: BMP2-loaded nanoporous silica nanoparticles promote osteogenic differentiation of human mesenchymal stem cells
Paper

A bioactive Ti metal with a Ca-enriched surface layer releases Mg ions

A bioactive surface layer that released Mg2+ ions was produced on the surface of titanium metal (Ti) by chemical and heat treatments.

Graphical abstract: A bioactive Ti metal with a Ca-enriched surface layer releases Mg ions
Paper

Biomimetic calcium–phosphates produced by an auto-catalytic route on stainless steel 316L and bio-inert polyolefin

Calcium-phosphate by new autocatalytic bath on 316L and PP-PE improves cells density in PP-PE (A) and 316L (C) compared to the untreated PP-PE (B) and 316 L (D).

Graphical abstract: Biomimetic calcium–phosphates produced by an auto-catalytic route on stainless steel 316L and bio-inert polyolefin
Paper

Crystal structure and chemical composition of biomimetic calcium phosphate nanofibers

A structural and chemical analysis of nanofibers synthesized via interfacial mineralization of calcium phosphate beneath monolayers of poly(n-butylmethacrylate)-block-poly[2-(dimethylamino)ethyl methacrylate] at the air–water interface.

Graphical abstract: Crystal structure and chemical composition of biomimetic calcium phosphate nanofibers
Paper

Titania nanotube porosity controls dissolution rate of sputter deposited calcium phosphate (CaP) thin film coatings

Titanium nanotube porosity to control the dissolution of sputter deposited calcium phosphate thin films.

Graphical abstract: Titania nanotube porosity controls dissolution rate of sputter deposited calcium phosphate (CaP) thin film coatings
Paper

MiR-148b laden titanium implant promoting osteogenic differentiation of rat bone marrow mesenchymal stem cells

Functionalizing titanium (Ti) implants with bioactive agents appears to be attractive for accelerating osseointegration.

Graphical abstract: MiR-148b laden titanium implant promoting osteogenic differentiation of rat bone marrow mesenchymal stem cells
Paper

Inner surface modification of the tube-like elements for medical applications

Novel aspects are polymer tubes for external and internal blood circulation modified with non-cytotoxic and anti-thrombogenic coatings tested through advanced interdisciplinary biophysical investigations on blood in patient-like conditions.

Graphical abstract: Inner surface modification of the tube-like elements for medical applications
Paper

Preparation of a silicate-containing hydroxyapatite-based coating by magnetron sputtering: structure and osteoblast-like MG63 cells in vitro study

Silicate-containing hydroxyapatite-based coatings with different structure and calcium/phosphate ratios were prepared by rf-magnetron sputtering.

Graphical abstract: Preparation of a silicate-containing hydroxyapatite-based coating by magnetron sputtering: structure and osteoblast-like MG63 cells in vitro study
Paper

Electrophoretic deposition of nanostructured-TiO2/chitosan composite coatings on stainless steel

Novel bioactive nanostructured-TiO2/chitosan coatings obtained by electrophoretic deposition with tailored contact angle and corrosion protection for orthopaedic devices.

Graphical abstract: Electrophoretic deposition of nanostructured-TiO2/chitosan composite coatings on stainless steel
Paper

Morphology and structure of antibacterial nanocomposite organic–polymer and metal–polymer coatings deposited from active gas phase

The synthesis of nanocomposite polymer-based coatings was produced from active gas phase formed by electron beam dispersion of polymer and biocide agent in vacuum.

Graphical abstract: Morphology and structure of antibacterial nanocomposite organic–polymer and metal–polymer coatings deposited from active gas phase
Paper

Enhanced bioactivity and bacteriostasis effect of TiO2 nanofilms with favorable biomimetic architectures on titanium surface

TiO2 nanofilms on a titanium surface prepared by hydrothermal treatment are of hierarchical architectures and exhibit improved bioactivity and bacteriostasis.

Graphical abstract: Enhanced bioactivity and bacteriostasis effect of TiO2 nanofilms with favorable biomimetic architectures on titanium surface
Paper

Osteoblast responses to novel titanium-based surfaces produced by plasma- and ion beam technologies

Novel Ti-based layers prepared by plasma and ion beam technologies were demonstrated to have good cytocompatibility and are suitable for application in biomedicine.

Graphical abstract: Osteoblast responses to novel titanium-based surfaces produced by plasma- and ion beam technologies
Paper

Alginate/silica composite hydrogel as a potential morphogenetically active scaffold for three-dimensional tissue engineering

Bead-encapsulation of bone cells is a useful technique to produce bioactive programmable hydrogels.

Graphical abstract: Alginate/silica composite hydrogel as a potential morphogenetically active scaffold for three-dimensional tissue engineering
Paper

Formation of bioactive coatings on Ti–13Nb–13Zr alloy for hard tissue implants

We obtain a bioactive coating on the Ti–13Nb–13Zr alloy via plasma electrolytic oxidation and additional alkali treatment.

Graphical abstract: Formation of bioactive coatings on Ti–13Nb–13Zr alloy for hard tissue implants
Paper

Deposition and characterization of a dual-layer silicon- and silver-containing hydroxyapatite coating via a drop-on-demand technique

Silicon-containing hydroxyapatite (SiHA) and silver-containing hydroxyapatite (AgHA) have been shown to provide enhanced bioactivity and antibacterial properties over pure hydroxyapatite (HA), respectively.

Graphical abstract: Deposition and characterization of a dual-layer silicon- and silver-containing hydroxyapatite coating via a drop-on-demand technique
Paper

Enhanced osteoblast functions of narrow interligand spaced Sr-HA nano-fibers/rods grown on microporous titania coatings

Nanofibrous and nanorod-shaped Sr1-HA with lateral spacing of less than 100 nm, and nanogranulated Ca0.5Sr0.5TiO3 were hydrothermally grown on micro-arc oxidized microporous and nanocrystallized TiO2, respectively, to form multilayer coatings.

Graphical abstract: Enhanced osteoblast functions of narrow interligand spaced Sr-HA nano-fibers/rods grown on microporous titania coatings
Paper

Influence of precursor chemistry on CVD grown TiO2 coatings: differential cell growth and biocompatibility

Titania (TiO2) films of different phase compositions and surface topographies grown from chemically different precursors showed markedly different bioresponses, manifested in differential cell growth and proliferation behaviour.

Graphical abstract: Influence of precursor chemistry on CVD grown TiO2 coatings: differential cell growth and biocompatibility
Paper

A genetically active nano-calcium phosphate paste for bone substitution, encoding the formation of BMP-7 and VEGF-A

Calcium phosphate nanoparticles with different compositions and morphologies were prepared and loaded with DNA. These nanoparticles can be used for transfection of different cell types and are highly biocompatible.

Graphical abstract: A genetically active nano-calcium phosphate paste for bone substitution, encoding the formation of BMP-7 and VEGF-A
Paper

Human osteoblast-like cells response to pulsed electrodeposited calcium phosphate coatings

The biocompatibility of a calcium phosphate coating synthesized by pulsed electrodeposition is assessed by observing its behaviour in contact with human osteoblast-like cells (MG-63).

Graphical abstract: Human osteoblast-like cells response to pulsed electrodeposited calcium phosphate coatings
Paper

An approach to a biomimetic bone scaffold: increased expression of BMP-2 and of osteoprotegerin in SaOS-2 cells grown onto silica-biologized 3D printed scaffolds

SaOS-2 cells growing on 3D printed grids formed of silica-impregnated Ca-sulfate retain the ability to express osteoprotegerin and BMP-2, suggesting that 3D printed matrices, processed with silica, might function also as a morphogenetic material in vivo.

Graphical abstract: An approach to a biomimetic bone scaffold: increased expression of BMP-2 and of osteoprotegerin in SaOS-2 cells grown onto silica-biologized 3D printed scaffolds
28 items

About this collection

Welcome to this themed collection on 'Bioactive surfaces for hard tissue regeneration', Guest Edited by Professor Matthias Epple (University of Duisburg-Essen, Essen, Germany) and Professor Roman Surmenev (National Research Tomsk Polytechnic University, Tomsk, Russia).

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