Effects of quercetin on the DNA methylation pattern in tumor therapy: an updated review
Quercetin reverses the expression of abnormal genes by regulating DNA methylation, and is an important regulator of gene transcription in tumorigenesis. The use of nanoscale delivery of quercetin increases its bioavailability in cancer therapy.
Review Article
Edible insects as a source of biopeptides and their role in immunonutrition
Edible insect species are attracting the attention of the food industry and consumers in Western societies due to their high content and quality of protein, which is starting to be evaluated as source of peptides with immunomodulatory properties.
Associations between dietary macronutrient quality and asthenozoospermia risk: a hospital-based case-control study
Dietary macronutrient quality and asthenozoospermia risk.
Paper
Efficacy and safety of galacto-oligosaccharide in the treatment of functional constipation: randomized clinical trial
The efficacy and safety of galacto-oligosaccharides (GOS) in treating functional constipation were evaluated in a four-week randomized, double-blind clinical trial on 63 patients who met Rome IV criteria (34 GOS, 29 placebo group).
Fucoxanthin alleviates lipopolysaccharide-induced intestinal barrier injury in mice
Fx effectively prevents LPS-induced intestinal barrier injury via inhibiting intestinal inflammation and oxidative stress.
Protection effect of lutein-loaded Pickering emulsion prepared via ultrasound-assisted Maillard reaction conjugates on dry age-related macular degeneration
Age-related macular degeneration (AMD) is a prominent cause of vision loss among the elderly, and the treatment options for dry AMD (dAMD) are severely limited.
Carboxymethylated Lycium barbarum seed dreg dietary fiber alleviates high fat diet-induced hyperlipidemia in mice via intestinal regulation
The carboxymethylated Lycium barbarum seed dreg insoluble dietary fiber (IDFs) significantly alleviated HFD-induced dyslipidemia, inflammation and hepatocyte degeneration, and ameliorated gut dysbiosis and increased SCFAs levels in obese mice.
Improving insulin resistance by sulforaphane via activating Bacteroides & Lactobacillus-SCFAs-GPR-GLP1 signal axis
Chronic consumption of a bergamot-based beverage does not affect glucose, lipid and inflammatory biomarkers of cardiometabolic risk in healthy subjects: a randomised controlled intervention study
A bergamot-based beverage does not affect glucose, lipid and inflammatory biomarkers of cardiometabolic risk in healthy subjects.
Paper
A red-fleshed apple rich in anthocyanins improves endothelial function, reduces inflammation, and modulates the immune system in hypercholesterolemic subjects: the AppleCOR study
Red-fleshed apples (RFA), improve endothelial function and decrease inflammation. RFA induce more improvements in inflammation than aronia infusion (AI), whereas AI improves lipid profile. RFA, white-fleshed apples and AI modulate immune system.
Heat-moisture and acid treatments can increase levels of resistant starch in arrowroot starch without adversely affecting its prebiotic activity in human colon microbiota
Carbohydrates are an important macronutrient whose processing and digestive fate can have numerous beneficial or adverse effects on consumer health.
Efficient regioselective enzymatic acylation of troxerutin: difference characterization of in vitro cellular uptake and cytotoxicity
Multi-site acylation of troxerutin can solve the problems of cytotoxicity and rapid hydrolysis of ester bonds caused by mono-acylation and increase cellular uptake.
Long-term administration of royal jelly regulates age-related disorders and improves gut function in naturally aging mice
A natural aging mouse model can exhibit physiological characteristics that closely resemble those of human aging.
The dairy-derived peptide Miltin exerts anti-obesity effects by increasing adipocyte thermogenesis
Miltin, a dairy-derived peptide, activates the thermogenic programs in brown and white adipocytes by directly interacting with GADD45r.
Bioactive components and mechanisms of Pu-erh tea in improving levodopa metabolism in rats through COMT inhibition
Pu-erh tea can enhance the efficacy of levodopa in treating Parkinson's disease by inhibiting COMT activity and improving levodopa's pharmacokinetic behavior in rats.
Litchi pulp-derived gamma-aminobutyric acid (GABA) extract counteracts liver inflammation induced by litchi thaumatin-like protein
Gamma-aminobutyric acid (GABA) is the predominant amino acid in litchi pulp, known for its neuroregulatory effects and anti-inflammatory properties.
The synergism of Lactobacillaceae, inulin, polyglucose, and aerobic exercise ameliorates hyperglycemia by modulating the gut microbiota community and the metabolic profiles in db/db mice
This study aimed to assess the impact of Lactobacillaceae (L or H represents a low or high dose), inulin (I), and polydextrose (P) combined with aerobic exercise (A) on the composition of the gut microbiota and metabolic profiles in db/db mice.
Paper
Pomegranate supplementation alleviates dyslipidemia and the onset of non-alcoholic fatty liver disease in Wistar rats by shifting microbiota and producing urolithin-like microbial metabolites
Pomegranate supplemetation decreased fat depots, counteracted the dyslipidemia caused by fructose and improved markers of liver injury. Microbial metabolites from pomegranate may be responsible for these health benefits.
Bifidobacterium pseudocatenulatum NCU-08 ameliorated senescence via modulation of the AMPK/Sirt1 signaling pathway and gut microbiota in mice
Mechanisms of B. pseudocatenulatum NCU-08 in mitigating aging via the microbiota–gut–brain axis.
Paper
Nutritional profiling, fiber content and in vitro bioactivities of wheat-based biscuits formulated with novel ingredients
Designing a cereal-based product with added nutritional value and health-enhancing effects.
Paper
Increased nitrate intake from beetroot juice over 4 weeks affects nitrate metabolism, but not vascular function or blood pressure in older adults with hypertension
In this randomized placebo-controlled crossover study, we evaluated whether previously reported cardiovascular benefits of plant-derived inorganic nitrate via NO translate into improved vascular function and blood pressure-lowering in middle-aged and older men and women with treated hypertension.
Structure characteristics, protective effect and mechanisms of ethanol-fractional polysaccharides from Dendrobium officinale on acute ethanol-induced gastritis
Gastritis is a common disease characterized by gastric ulcers and severe bleeding.
Long-term intake of thermo-induced oxidized oil results in anxiety-like and depression-like behaviors: involvement of microglia and astrocytes
Frequent consumption of fried foods has been strongly associated with a higher risk of anxiety and depression, particularly among young individuals.
Dietary lipoic acid alleviates autism-like behavior induced by acrylamide in adolescent mice: the potential involvement of the gut–brain axis
Lipoic acid (LA) ameliorated acrylamide (ACR)-induced social impairment in adolescent mice. Lipoic acid (LA) reshaped gut microbiota and its metabolites. Lipoic acid (LA) regulated serum amino acid level.
Green tea polyphenols inhibit TBBPA-induced lung injury via enhancing antioxidant capacity and modulating the NF-κB pathway in mice
Tetrabromobisphenol A (TBBPA) is a global pollutant. When TBBPA is absorbed by the body through various routes, it can have a wide range of harmful effects on the body.
Neuroprotective effects of probiotics on anxiety- and depression-like disorders in stressed mice by modulating tryptophan metabolism and the gut microbiota
Lactiplantibacillus plantarum D-9 shows neuroprotective effects on anxiety- and depression-like disorders in CUMS mice by modulating tryptophan metabolism and the gut microbiota.
Exploring novel Kokumi peptides in Agaricus bisporus: selection, identification, and tasting mechanism investigation through sensory evaluation and computer simulation analysis
Two novel Kokumi peptides, identified from Agaricus bisporus via sensory and computer analyses, potentially enhance umami taste and reduce salt intake.
Association between adequate dietary protein and all-cause and cardiovascular mortality in patients with selective glomerular hypofiltration syndrome
We studied how protein intake and sources affect selective glomerular hypofiltration syndrome patients' mortality. More protein (mainly from non-red meat) lowered death risk by 40% (all-cause) and 88% (cardiovascular).
Mitigation of high-fat diet-induced hepatic steatosis by thyme (Thymus quinquecostatus Celak) polyphenol-rich extract (TPE): insights into gut microbiota modulation and bile acid metabolism
Thyme polyphenol-rich extract effectively mitigate HFD- induced NAFLD by modulating the gut-liver axis, specifically targeting the gut microbiota and bile acid metabolism.
About this collection
This themed collection features articles published in Food & Function marked as HOT by the handling editor or as recommended by referees. Congratulations to all the authors whose articles are featured.