Themed collection Editor’s Choice: Microfluidics

21 items
Editorial

Journal of Materials Chemistry B and Biomaterials Science Editor's choice web collection: “Recent advances in microfluidics”

Guoping Chen introduces a Journal of Materials Chemistry B and Biomaterials Science Editor's choice web collection on recent advances in microfluidics.

Graphical abstract: Journal of Materials Chemistry B and Biomaterials Science Editor's choice web collection: “Recent advances in microfluidics”
From the themed collection: Editor’s Choice: Microfluidics
Review Article

Microphysiological systems for the modeling of wound healing and evaluation of pro-healing therapies

Wound healing microphysiological systems have been engineered with synthetic and natural materials and techniques such as bioprinting or viscous finger patterning. Model designs focus on particular phases of wound healing or the recapitulation of micro-anatomies.

Graphical abstract: Microphysiological systems for the modeling of wound healing and evaluation of pro-healing therapies
From the themed collection: Editor’s Choice: Microfluidics
Review Article

From cells-on-a-chip to organs-on-a-chip: scaffolding materials for 3D cell culture in microfluidics

Integrating ECM materials in microfluidics for 3D cell culture.

Graphical abstract: From cells-on-a-chip to organs-on-a-chip: scaffolding materials for 3D cell culture in microfluidics
From the themed collection: Editor’s Choice: Microfluidics
Review Article

Aptamer-based nanostructured interfaces for the detection and release of circulating tumor cells

This paper summarizes various aptamer-functionalized nanostructured interfaces for the detection and release of circulating tumor cells.

Graphical abstract: Aptamer-based nanostructured interfaces for the detection and release of circulating tumor cells
From the themed collection: Editor’s Choice: Microfluidics
Review Article

Advances in functional nucleic acid based paper sensors

This article provides an extensive review of paper-based sensors that utilize functional nucleic acids, particularly DNA aptamers and DNAzymes, as recognition elements.

Graphical abstract: Advances in functional nucleic acid based paper sensors
From the themed collection: Editor’s Choice: Microfluidics
Review Article

Biosensors and bioassays for determination of matrix metalloproteinases: state of the art and recent advances

This review highlights the recent advances in nanomaterial-based immunoassays for MMP abundance measurements and nanomaterial-based biosensors for MMP activity determination.

Graphical abstract: Biosensors and bioassays for determination of matrix metalloproteinases: state of the art and recent advances
From the themed collection: Editor’s Choice: Microfluidics
Review Article

Microfluidics for ZnO micro-/nanomaterials development: rational design, controllable synthesis, and on-chip bioapplications

This review provides a comprehensive summary of recent advances in microfluidics-enabled controllable synthesis and bioapplications of ZnO micro-/nanomaterials.

Graphical abstract: Microfluidics for ZnO micro-/nanomaterials development: rational design, controllable synthesis, and on-chip bioapplications
From the themed collection: Editor’s Choice: Microfluidics
Open Access Communication

All-in-one microfluidic assembly of insulin-loaded pH-responsive nano-in-microparticles for oral insulin delivery

Here, a continuous two-step glass-capillary microfluidic technique to produce a multistage oral insulin delivery system is reported. This system represents a promising alternative for the common protein/peptide-loaded liposome formulations.

Graphical abstract: All-in-one microfluidic assembly of insulin-loaded pH-responsive nano-in-microparticles for oral insulin delivery
From the themed collection: Editor’s Choice: Microfluidics
Communication

Multiphasic microgel-in-gel materials to recapitulate cellular mesoenvironments in vitro

Cell-instructive biohybrid microgel-in-gel materials can guide the faithful in vitro reconstitution of tissues.

Graphical abstract: Multiphasic microgel-in-gel materials to recapitulate cellular mesoenvironments in vitro
From the themed collection: Editor’s Choice: Microfluidics
Open Access Paper

Combined effect of shear stress and laser-patterned topography on Schwann cell outgrowth: synergistic or antagonistic?

Shear stress can act either synergistically or antagonistically with topographical cues in specific cell responses such as orientation and elongation.

Graphical abstract: Combined effect of shear stress and laser-patterned topography on Schwann cell outgrowth: synergistic or antagonistic?
From the themed collection: Editor’s Choice: Microfluidics
Paper

Continuous flow fabrication of Fmoc-cysteine based nanobowl infused core–shell like microstructures for pH switchable on-demand anti-cancer drug delivery

pH responsive core–shell nanobowl-microstructures (NB-shells) as novel and exciting platforms for stimuli activated drug delivery applications.

Graphical abstract: Continuous flow fabrication of Fmoc-cysteine based nanobowl infused core–shell like microstructures for pH switchable on-demand anti-cancer drug delivery
From the themed collection: Editor’s Choice: Microfluidics
Paper

PLGA/chitosan–heparin composite microparticles prepared with microfluidics for the construction of hMSC aggregates

P/C–h composite microparticles fabricated by microfluidics enhanced the biological functions of hMSC aggregates through neutralizing PLGA′ acidic degradation products.

Graphical abstract: PLGA/chitosan–heparin composite microparticles prepared with microfluidics for the construction of hMSC aggregates
From the themed collection: Editor’s Choice: Microfluidics
Open Access Paper

Exploring microfluidics as a tool to evaluate the biological properties of a titanium alloy under dynamic conditions

When evaluating the biological properties of titanium under dynamic conditions, cell proliferation was shown to be dominant over cell differentiation.

Graphical abstract: Exploring microfluidics as a tool to evaluate the biological properties of a titanium alloy under dynamic conditions
From the themed collection: Editor’s Choice: Microfluidics
Paper

One-step synthesis of composite hydrogel capsules to support liver organoid generation from hiPSCs

One-step synthesis of composite hydrogel capsules (CHCs) that allow engineering hiPSC-derived liver organoids in an oil-free droplet microfluidic system.

Graphical abstract: One-step synthesis of composite hydrogel capsules to support liver organoid generation from hiPSCs
From the themed collection: Editor’s Choice: Microfluidics
Paper

Colorimetric detection of urine glucose using a C/CdTe QDs–GOx aerogel based on a microfluidic assay sensor

A sensitive fluorescent microfluidic sensor based on carbon quantum dots (CQDs), cadmium telluride quantum dots (CdTe QDs) aerogel and glucose oxidase (GOx) for urinal glucose detection was fabricated via a simple method.

Graphical abstract: Colorimetric detection of urine glucose using a C/CdTe QDs–GOx aerogel based on a microfluidic assay sensor
From the themed collection: Editor’s Choice: Microfluidics
Paper

A microfluidics-derived growth factor gradient in a scaffold regulates stem cell activities for tendon-to-bone interface healing

Treatment of tendon-to-bone interface injury has long been challenging in sports medicine.

Graphical abstract: A microfluidics-derived growth factor gradient in a scaffold regulates stem cell activities for tendon-to-bone interface healing
From the themed collection: Editor’s Choice: Microfluidics
Paper

Tumor localization of oncolytic adenovirus assisted by pH-degradable microgels with JQ1-mediated boosting replication and PD-L1 suppression for enhanced cancer therapy

Illustration of pH-degradable microgels (MGs) for the simultaneous encapsulation of OA and JQ1 for an enhanced oncolytic viral treatment with JQ1-meidated boosting viral replication and PD-L1 suppression.

Graphical abstract: Tumor localization of oncolytic adenovirus assisted by pH-degradable microgels with JQ1-mediated boosting replication and PD-L1 suppression for enhanced cancer therapy
From the themed collection: Editor’s Choice: Microfluidics
Paper

Boosting biomolecular interactions through DNA origami nano-tailored biosensing interfaces

Nano-tailored DNA origami designs nanostructure the bioreceptor layer of encoded microparticles in an innovative microfluidic platform, hereby boosting biomolecular interactions.

Graphical abstract: Boosting biomolecular interactions through DNA origami nano-tailored biosensing interfaces
From the themed collection: Editor’s Choice: Microfluidics
Paper

Modulating the properties of flow-assembled chitosan membranes in microfluidics with glutaraldehyde crosslinking

Glutaraldehyde crosslinking significantly enhances the mechanical robustness of the originally compromised flow-assembled chitosan membranes after Pluronic passivation in microfluidics.

Graphical abstract: Modulating the properties of flow-assembled chitosan membranes in microfluidics with glutaraldehyde crosslinking
From the themed collection: Editor’s Choice: Microfluidics
Paper

Microencapsulation improves chondrogenesis in vitro and cartilaginous matrix stability in vivo compared to bulk encapsulation

The encapsulation of cells into microgels is attractive for applications in tissue regeneration.

Graphical abstract: Microencapsulation improves chondrogenesis in vitro and cartilaginous matrix stability in vivo compared to bulk encapsulation
From the themed collection: Editor’s Choice: Microfluidics
Paper

Characterization and application of fluidic properties of trinucleotide repeat sequences by wax-on-plastic microfluidics

This work demonstrates sequence directed flexibility of neurodegenerative trinucleotide repeat sequences can be translated into distinct capillary flow using wax-on-plastic microfluidics and used to detect microsatellite repeat expansions diseases.

Graphical abstract: Characterization and application of fluidic properties of trinucleotide repeat sequences by wax-on-plastic microfluidics
From the themed collection: Editor’s Choice: Microfluidics
21 items

About this collection

Associate Editor for Journal of Materials Chemistry B and Advisory Board Member for Biomaterials Science, Guoping Chen (National Institute for Materials Science, Japan), has selected a few outstanding recent manuscripts on Microfluidics for this Editor’s Choice collection. In order to highlight developments in microfluidics, this online collection includes recent manuscripts from Biomaterials Science and Journal of Materials Chemistry B on the topic.

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