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Themed collection Microfluidic systems with societal impact

27 items
Editorial

Microfluidics systems with societal impact in Analytical Methods

Guest Editors Michael Roper, Christopher Easley and Fiona Regan, alongside Deputy Editor Maria Southall, introduce the Analytical Methods themed collection on microfluidic systems.

Graphical abstract: Microfluidics systems with societal impact in Analytical Methods
From the themed collection: Microfluidic systems with societal impact
Editorial

In celebration of the 60th birthday of 2 microfluidics pioneers: Professor Susan Lunte and Professor James Landers

Christopher Easley, Fiona Regan, Michael Roper and R. Scott Martin look at the achievements of Susan Lunte and James Landers.

Graphical abstract: In celebration of the 60th birthday of 2 microfluidics pioneers: Professor Susan Lunte and Professor James Landers
From the themed collection: Microfluidic systems with societal impact
Minireview

Microfluidics in coagulation monitoring devices: a mini review

Diagnosis and monitoring of disorders of coagulation and disturbances in haemostasis has been around for many years. The development of POC technologies in this area has rapidly advanced and continues to improve upon the monitoring and diagnosis of these disorders. This review highlights recent and ongoing advances in microfluidics with application to the areas of haemostasis and coagulation biology.

Graphical abstract: Microfluidics in coagulation monitoring devices: a mini review
From the themed collection: Recent Review Articles
Minireview

Integrated paper-based microfluidic devices for point-of-care testing

This review highlights the developments, accomplishments and challenges of integrated μPADs, including sample pretreatment, signal transduction/amplification and results output.

Graphical abstract: Integrated paper-based microfluidic devices for point-of-care testing
From the themed collection: Recent Review Articles
Minireview

Recent advances in an organ-on-a-chip: biomarker analysis and applications

Recent advances in high-throughput biomarker analysis based on an organ-on-a-chip and its applications in drug development.

Graphical abstract: Recent advances in an organ-on-a-chip: biomarker analysis and applications
From the themed collection: Recent Review Articles
Tutorial Review

Flow-gated capillary electrophoresis: a powerful technique for rapid and efficient chemical separation

Flow-gated capillary electrophoresis (CE) is a hybrid of conventional and microchip CE since it employs a fused silica capillary as the separation channel while taking advantage of the well-controlled flow-gated injection, which adds versatility in terms of separation efficiency, analytical throughput, and ease of coupling with sample pretreatment procedures.

Graphical abstract: Flow-gated capillary electrophoresis: a powerful technique for rapid and efficient chemical separation
From the themed collection: Recent Review Articles
Critical Review

Recent advances in toner-based microfluidic devices for bioanalytical applications

Toner-based microfluidic devices have emerged as promising platforms for bioanalytical applications.

Graphical abstract: Recent advances in toner-based microfluidic devices for bioanalytical applications
From the themed collection: Recent Review Articles
Critical Review

A review of centrifugal microfluidics in environmental monitoring

There is currently a gap in the use of centrifugal microfluidics in the field of environmental sensing.

Graphical abstract: A review of centrifugal microfluidics in environmental monitoring
From the themed collection: Recent Review Articles
Open Access Paper

Accurate flow in augmented networks (AFAN): an approach to generating three-dimensional biomimetic microfluidic networks with controlled flow

A network augmentation approach that adds synthetic connections to microvascular networks to induce biomimetic microfluidic flow.

Graphical abstract: Accurate flow in augmented networks (AFAN): an approach to generating three-dimensional biomimetic microfluidic networks with controlled flow
From the themed collection: Analytical Methods Recent HOT articles
Paper

Single board computing system for automated colorimetric analysis on low-cost analytical devices

Colorimetric detection, while a user-friendly and easily implemented method of analysis on low-cost analytical devices, often suffers from subjectivity by the device user.

Graphical abstract: Single board computing system for automated colorimetric analysis on low-cost analytical devices
From the themed collection: Analytical Methods Recent HOT articles
Paper

Rapid fabrication of versatile omni-directional and long-distance three-dimensional flow paper-fluidic analytical devices using a cut-and-insert method for biomedical applications

Paper fluidics has recently offered an approach to precisely guide liquid flow in analytical devices with a low-cost regime.

Graphical abstract: Rapid fabrication of versatile omni-directional and long-distance three-dimensional flow paper-fluidic analytical devices using a cut-and-insert method for biomedical applications
From the themed collection: Analytical Methods Recent HOT articles
Paper

Droplet microfluidics in thermoplastics: device fabrication, droplet generation, and content manipulation using integrated electric and magnetic fields

Droplet microfluidic devices with integrated operations including droplet generation, electrical injection, and magnetic splitting were manufactured in thermoplastics.

Graphical abstract: Droplet microfluidics in thermoplastics: device fabrication, droplet generation, and content manipulation using integrated electric and magnetic fields
From the themed collection: Microfluidic systems with societal impact
Paper

Carbon tape as a convenient electrode material for electrochemical paper-based microfluidic devices (ePADs)

ePADs represent an innovative and versatile platform for fluid handling and analysis.

Graphical abstract: Carbon tape as a convenient electrode material for electrochemical paper-based microfluidic devices (ePADs)
From the themed collection: Analytical Methods Recent HOT articles
Paper

Photolithographic structuring of soft, extremely foldable and autoclavable hydrophobic barriers in paper

Method for photolithographic structuring of foldable hydrophobic barriers in paper for the creation of microfluidic paper-based analytical devices (μPADs).

Graphical abstract: Photolithographic structuring of soft, extremely foldable and autoclavable hydrophobic barriers in paper
From the themed collection: Microfluidic systems with societal impact
Paper

Continuous monitoring of adenosine and its metabolites using microdialysis coupled to microchip electrophoresis with amperometric detection

Reversibly sealed all-PDMS device with CF working electrode for continuous on-line analysis of microdialysis samples.

Graphical abstract: Continuous monitoring of adenosine and its metabolites using microdialysis coupled to microchip electrophoresis with amperometric detection
From the themed collection: Analytical Methods Recent HOT articles
Paper

Characterization of low adsorption filter membranes for electrophoresis and electrokinetic sample manipulations in microfluidic paper-based analytical devices

Low adsorption filter membrane materials facilitate effective zonal electrophoresis and electrokinetic gating in microfluidic paper-based analytical devices (μPADs).

Graphical abstract: Characterization of low adsorption filter membranes for electrophoresis and electrokinetic sample manipulations in microfluidic paper-based analytical devices
From the themed collection: Analytical Methods Emerging Investigators
Paper

Advancement of analytical modes in a multichannel, microfluidic droplet-based sample chopper employing phase-locked detection

Multichannel droplet-based microfluidic sample chopper (μChopper) allows continuous calibration, nanoliter sampling, and protein quantification in human serum.

Graphical abstract: Advancement of analytical modes in a multichannel, microfluidic droplet-based sample chopper employing phase-locked detection
From the themed collection: Analytical Methods Recent HOT articles
Paper

Use of 3D printing and modular microfluidics to integrate cell culture, injections and electrochemical analysis

Here we show that separate modules fabricated using 3D printing technology can be easily assembled to quantitate the amount of nitric oxide released from endothelial cells following ATP stimulation.

Graphical abstract: Use of 3D printing and modular microfluidics to integrate cell culture, injections and electrochemical analysis
From the themed collection: Microfluidic systems with societal impact
Paper

Steroid inhibition of erythrocyte-derived ATP reduces endothelial cell production of nitric oxide in a 3D-printed fluidic model

Multiple sclerosis (MS) is a disease of the central nervous system affecting over 2.5 million people worldwide.

Graphical abstract: Steroid inhibition of erythrocyte-derived ATP reduces endothelial cell production of nitric oxide in a 3D-printed fluidic model
From the themed collection: Microfluidic systems with societal impact
Paper

A low-cost integrated biosensing platform based on SiN nanophotonics for biomarker detection in urine

We present a low-cost integrated nanophotonic lab-on-a-chip platform suitable for point-of-care (POC) biomarker analysis.

Graphical abstract: A low-cost integrated biosensing platform based on SiN nanophotonics for biomarker detection in urine
From the themed collection: Microfluidic systems with societal impact
Paper

New paper-based microfluidic tools for the analysis of blood serum protein and creatinine built via aerosolized deposition of polycaprolactone

Aerosolized deposition of a polymer solution to a substrate allows for rapid, low-cost fabrication of 3D microfluidic devices for bioassays.

Graphical abstract: New paper-based microfluidic tools for the analysis of blood serum protein and creatinine built via aerosolized deposition of polycaprolactone
From the themed collection: Analytical Methods Recent HOT articles
Paper

An all thiol–ene microchip for solid phase extraction featuring an in situ polymerized monolith and integrated 3D replica-molded emitter for direct electrospray mass spectrometry

Pre-concentration and clean-up are essential sample preparation steps in environmental, forensics and bio-analytical assays.

Graphical abstract: An all thiol–ene microchip for solid phase extraction featuring an in situ polymerized monolith and integrated 3D replica-molded emitter for direct electrospray mass spectrometry
From the themed collection: Microfluidic systems with societal impact
Paper

A pilot study in humans of microneedle sensor arrays for continuous glucose monitoring

Although subcutaneously implanted continuous glucose monitoring (CGM) devices have been shown to support diabetes self-management, their uptake remains low due to high costs and poor accuracy and precision arising from their invasiveness.

Graphical abstract: A pilot study in humans of microneedle sensor arrays for continuous glucose monitoring
From the themed collection: Microfluidic systems with societal impact
Paper

Label-free mesenchymal stem cell enrichment from bone marrow samples by inertial microfluidics

Isolation of pure populations of mesenchymal stem cells from bone marrow aspirate is a critical need in regenerative medicine such as orthopedic and cartilage reconstruction with important clinical and therapeutic implications.

Graphical abstract: Label-free mesenchymal stem cell enrichment from bone marrow samples by inertial microfluidics
From the themed collection: Microfluidic systems with societal impact
Paper

Enhanced microchip electrophoresis separations combined with electrochemical detection utilizing a capillary embedded in polystyrene

A polystyrene–PDMS device utilizing an embedded fused silica capillary and electrochemical detection was used for improved efficiency separations of catecholamines.

Graphical abstract: Enhanced microchip electrophoresis separations combined with electrochemical detection utilizing a capillary embedded in polystyrene
From the themed collection: Analytical Methods Recent HOT articles
Paper

Microfluidic detection with acoustic spectroscopy (MIDAS) for analysis of insulin formulation stability

Ultrasonic spectroscopy is a viable complement to current techniques used to analyze insulin stability due to its simplicity, lack of sample preparation, and non-destructive properties.

Graphical abstract: Microfluidic detection with acoustic spectroscopy (MIDAS) for analysis of insulin formulation stability
From the themed collection: Microfluidic systems with societal impact
Technical Note

Automated 4-sample protein immunoassays using 3D-printed microfluidics

A 3D-printed microfluidic array detects 2 proteins in 4 samples at very low cost with downloadable plans

Graphical abstract: Automated 4-sample protein immunoassays using 3D-printed microfluidics
From the themed collection: Microfluidic systems with societal impact
27 items

About this collection

A collection of papers and reviews on micorlfluidics systems with societal impact. This multi-disciplinary field has seen growth in recent years due to its increasing applicability to a range of areas, from inkjet print heads to DNA chips. Due to the integration of microfluidic systems throughout science, the scope of this collection is intentionally broad and encompasses applications of these systems to diverse fields including biological, environmental, forensics and diagnostics. This collection is guest edited by Associate Editors Christopher Easley, Fiona Regan and Michael Roper. 
More details about the collection can be found at rsc.li/microfluidics-societal-impact-blog. The submission deadline for this collection is 30th April 2018. 

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