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Issue 29, 2018
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Integrated paper-based microfluidic devices for point-of-care testing

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Abstract

As a rapidly developing field, paper-based microfluidic devices (μPADs) are expected to have profound implications, especially for in vitro diagnosis. In particular, integrated μPADs, with the merits of capillary-driven force, cost effectiveness, mass production and ease of use, are emerging as ideal tools for personal diagnosis; sample collection/pretreatment, signal transduction and results output can be simplified into one μPAD with minimal need for complex operation. In this review, we emphasize the latest developments of integrated μPADs and highlight the accomplishments and challenges of each component, including sample collection/pretreatment, signal transduction and amplification, and results output. Moreover, we give an overview of the growing trend of novel integrated μPADs and analyze existing challenges as well as potential directions for integrated μPADs for point-of-care testing (POCT).

Graphical abstract: Integrated paper-based microfluidic devices for point-of-care testing

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Article information


Submitted
18 Apr 2018
Accepted
20 Jun 2018
First published
22 Jun 2018

Anal. Methods, 2018,10, 3567-3581
Article type
Minireview

Integrated paper-based microfluidic devices for point-of-care testing

T. Tian, Y. Bi, X. Xu, Z. Zhu and C. Yang, Anal. Methods, 2018, 10, 3567
DOI: 10.1039/C8AY00864G

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