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Themed collection Toxicology Research Recent HOT articles

19 items
Open Access Viewpoint

Collaboration, competition and publication in toxicology: views of British Toxicology Society members

BTS members offer their opinions and interesting suggestions for improvement around resourcing, collaboration, competition, infrastructure and peer review in toxicology.

Graphical abstract: Collaboration, competition and publication in toxicology: views of British Toxicology Society members
From the themed collection: Toxicology Research Recent HOT articles
Paper

New models for the time dependent toxicity of individual and combined toxicants

A new model for combination effects gives descriptions of additivity, independence, synergy and antagonism and explains the multiple shapes of isoboles.

Graphical abstract: New models for the time dependent toxicity of individual and combined toxicants
From the themed collection: Toxicology Research Recent HOT articles
Paper

In silico prediction of chemical aquatic toxicity for marine crustaceans via machine learning

Six machine learning methods combined with descriptors or fingerprints were employed to predict chemical toxicity on marine crustaceans.

Graphical abstract: In silico prediction of chemical aquatic toxicity for marine crustaceans via machine learning
From the themed collection: Toxicology Research Recent HOT articles
Paper

Distribution of toxicity values across different species and modes of action of pesticides from PESTIMEP and PPDB databases

Pesticides classified by mode of action as a source of predictive models of toxicity.

Graphical abstract: Distribution of toxicity values across different species and modes of action of pesticides from PESTIMEP and PPDB databases
From the themed collection: Toxicology Research Recent HOT articles
Paper

PM2.5 induced neurodegenerative-like changes in mice and the antagonistic effects of vitamin E

After PM2.5 exposure, ND-like changes were induced through oxidative stress and inflammation, Vit E could antagonise the effects.

Graphical abstract: PM2.5 induced neurodegenerative-like changes in mice and the antagonistic effects of vitamin E
From the themed collection: Toxicology Research Recent HOT articles
Paper

A simple model to solve a complex drug toxicity problem

DTI redefines drug toxicity, identifies hepatotoxic drugs, gives mechanistic insights, predicts clinical outcomes and has potential use as a screening tool.

Graphical abstract: A simple model to solve a complex drug toxicity problem
From the themed collection: Toxicology Research Recent HOT articles
Paper

Clusterin increases mitochondrial respiratory chain complex I activity and protects against hexavalent chromium-induced cytotoxicity in L-02 hepatocytes

Previous evidence revealed significant elevated liver cancer mortality in the areas where water was contaminated with hexavalent chromium [Cr(VI)], which highlighted that we should pay more attention to Cr(VI)-induced cytotoxicity in hepatocytes.

Graphical abstract: Clusterin increases mitochondrial respiratory chain complex I activity and protects against hexavalent chromium-induced cytotoxicity in L-02 hepatocytes
From the themed collection: Toxicology Research Recent HOT articles
Paper

Exploring the binding interaction between copper ions and Candida rugosa lipase

Copper ions enter the central group of the catalytic center of CRL and bind with CRL, resulting in a conformational change of the lipase. This in turn causes an increase in the enzyme activity.

Graphical abstract: Exploring the binding interaction between copper ions and Candida rugosa lipase
From the themed collection: Toxicology Research Recent HOT articles
Paper

Mitochondrial toxicity induced by a thiourea gold(I) complex: mitochondrial permeability transition and respiratory deficit

Gold(I) complexes have been widely used as antibacterial and antitumor agents for their excellent biological activities.

Graphical abstract: Mitochondrial toxicity induced by a thiourea gold(i) complex: mitochondrial permeability transition and respiratory deficit
From the themed collection: Toxicology Research Recent HOT articles
Paper

Ameliorative effects of quercetin against bisphenol A-caused oxidative stress in human erythrocytes: an in vitro and in silico study

Bisphenol A (BPA) is an endocrine disruptor of xenobiotic type, mainly used for the production of polycarbonate plastic, epoxy resins and non-polymer additives.

Graphical abstract: Ameliorative effects of quercetin against bisphenol A-caused oxidative stress in human erythrocytes: an in vitro and in silico study
From the themed collection: Toxicology Research Recent HOT articles
Paper

Surface functional groups affect CdTe QDs behavior at mitochondrial level

CdTe QDs functionalized with different groups showed different effects on mitochondrial membrane fluidity.

Graphical abstract: Surface functional groups affect CdTe QDs behavior at mitochondrial level
From the themed collection: Toxicology Research Recent HOT articles
Paper

A 3D human lung-on-a-chip model for nanotoxicity testing

The prevalent application of nanoparticles (NPs) has drawn intense concerns about their impact on the environment and human health.

Graphical abstract: A 3D human lung-on-a-chip model for nanotoxicity testing
From the themed collection: Toxicology Research Recent HOT articles
Paper

Deficit in the epidermal barrier induces toxicity and translocation of PEG modified graphene oxide in nematodes

Our data provide the molecular basis for the role of epidermal barrier against toxicity and translocation of nanomaterials in organisms.

Graphical abstract: Deficit in the epidermal barrier induces toxicity and translocation of PEG modified graphene oxide in nematodes
From the themed collection: Toxicology Research Recent HOT articles
Paper

The mitochondrial pathway is involved in sodium fluoride (NaF)-induced renal apoptosis in mice

The objective of the present study was to explore the molecular mechanism of apoptosis induced by sodium fluoride (NaF) in the mouse kidney by using the methods of flow cytometry, quantitative real-time polymerase chain reaction (qRT-PCR), western blotting, and experimental pathology.

Graphical abstract: The mitochondrial pathway is involved in sodium fluoride (NaF)-induced renal apoptosis in mice
From the themed collection: Toxicology Research Recent HOT articles
Paper

Hemolytic and cellular toxicology of a sulfanilamide-based nonionic surfactant: a niosomal carrier for hydrophobic drugs

Sulfanilamide based nonionic surfactant can self-assemble into haemocompatible and non-toxic niosomes that are promising for drug delivery.

Graphical abstract: Hemolytic and cellular toxicology of a sulfanilamide-based nonionic surfactant: a niosomal carrier for hydrophobic drugs
From the themed collection: Toxicology Research Recent HOT articles
Paper

Effect of the calcination process on CdO–ZnO nanocomposites by a honey-assisted combustion method for antimicrobial performance

This work reports on honey as a combustion agent of CdO : ZnO nanocomposites and the effects of further annealing on their structural, optical, morphological, elemental, electrical and antimicrobial properties are investigated.

Graphical abstract: Effect of the calcination process on CdO–ZnO nanocomposites by a honey-assisted combustion method for antimicrobial performance
From the themed collection: Toxicology Research Recent HOT articles
Paper

Correlation of the cytotoxic effects of cationic lipids with their headgroups

As effective non-viral vectors of gene therapy, cationic lipids still have the problem of toxicity, which has become one of the main bottlenecks for their applications.

Graphical abstract: Correlation of the cytotoxic effects of cationic lipids with their headgroups
From the themed collection: Toxicology Research Recent HOT articles
Paper

Amino-PAHs activated Nrf2/ARE anti-oxidative defense system and promoted inflammatory responses: the regulation of PI3K/Akt pathway

The amino polycyclic aromatic hydrocarbons (amino-PAHs) were frequently detected in PM2.5, and it was suggested that they contributed to the harmful health effects associated with PM2.5.

Graphical abstract: Amino-PAHs activated Nrf2/ARE anti-oxidative defense system and promoted inflammatory responses: the regulation of PI3K/Akt pathway
From the themed collection: Toxicology Research Recent HOT articles
Paper

Individual heavy metal exposure and birth outcomes in Shenqiu county along the Huai River Basin in China

Exposure to heavy metals during pregnancy is an important risk factor for adverse birth outcomes.

Graphical abstract: Individual heavy metal exposure and birth outcomes in Shenqiu county along the Huai River Basin in China
From the themed collection: Toxicology Research Recent HOT articles
19 items

About this collection

This themed collection features articles published in Toxicology Research marked as HOT by the handling editor or as recommended by referees. Congratulations to all the authors whose articles are featured.

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