Advanced electroanalytical chemistry at nanoelectrodes
In this perspective, we discuss the challenges, advances and opportunities in electroanalytical chemistry at nanoelectrodes, including nanoelectrode fabrication, real-time characterizations, and high-performance electrochemical instrumentation.
Sensing telomerase: From in vitro detection to in vivo imaging
We reviewed recent advances in telomerase assays including both in vitro detection and in vivo imaging.
Design of a ratiometric two-photon probe for imaging of hypochlorous acid (HClO) in wounded tissues
A ratiometric two-photon probe was designed to visualize HClO levels in tissues, revealing the generation of HClO in the wound-repairing process of mice for the first time.
Synthesis of a 2D phosphorus material in a MOF-based 2D nano-reactor
A 2D nano-reactor was constructed within a pillar–layer-MOF, in which a moderately stable 2D phosphorus material was synthesized.
White-light emission from a single organic compound with unique self-folded conformation and multistimuli responsiveness
White-light emission from a single molecule was realized and tuned via multistimuli including excitation, solvent polarity, temperature and host–guest interactions.
A pre-protective strategy for precise tumor targeting and efficient photodynamic therapy with a switchable DNA/upconversion nanocomposite
A pre-protective strategy for precise tumor targeting and efficient photodynamic therapy was developed using a switchable DNA/upconversion nanocomposite.
A mitochondria-targeted nanoradiosensitizer activating reactive oxygen species burst for enhanced radiation therapy
We developed a novel strategy for enhanced radiation therapy based on a mitochondria targeted titanium dioxide-gold nanoradiosensitizer.
Isotropic ordering of ions in ionic liquids on the sub-nanometer scale
This article investigates structures of ionic liquids.
Single quantum dot-based nanosensor for sensitive detection of 5-methylcytosine at both CpG and non-CpG sites
We develop a single quantum dot (QD)-based nanosensor for sensitive detection of DNA methylation at both CpG and non-CpG sites.
One-step solvothermal synthesis of high-emissive amphiphilic carbon dots via rigidity derivation
Here we report a chemical strategy that uses rigid molecules to straightforwardly construct amphiphilic carbon dots (ACDs) with high luminescence quantum yields (QYs).
Simultaneous sensitive detection of multiple DNA glycosylases from lung cancer cells at the single-molecule level
We demonstrate the simultaneous detection of human 8-oxoguanine DNA glycosylase 1 and human alkyladenine DNA glycosylase at the single-molecule level.
Doping palladium with tellurium for the highly selective electrocatalytic reduction of aqueous CO2 to CO
The doping of Pd with a small amount of Te can selectively convert CO2 to CO with a low overpotential.
A unified photoredox-catalysis strategy for C(sp3)–H hydroxylation and amidation using hypervalent iodine
We report a unified photoredox-catalysis strategy for both hydroxylation and amidation of tertiary and benzylic C–H bonds.
Total syntheses of schilancidilactones A and B, schilancitrilactone A, and 20-epi-schilancitrilactone A via late-stage nickel-catalyzed cross coupling
The first total syntheses of schilancidilactones A and B, schilancitrilactone A, and 20-epi-schilancitrilactone A have been accomplished.
Multi-functional bis(alkynyl)gold(III) N⁁C complexes with distinct mechanochromic luminescence and electroluminescence properties
A new class of highly luminescent bis(alkynyl)gold(III) N⁁C complexes has been utilized as emissive materials in OLEDs and exhibits mechanochromic behaviors.
Ratiometric photoacoustic imaging of endoplasmic reticulum polarity in injured liver tissues of diabetic mice
We have developed a new fluorescent and photoacoustic dual-mode probe, ER-P, for the detection of ER polarity of liver tissues in normal and diabetic mice.
One-pot synthesis of heterorotaxane bearing three different kinds of macrocycle through a self-sorting process
A heterorotaxane bearing three different kinds of macrocycle is designed and successfully synthesized through a one-pot “click” reaction by employing a facile and efficient integrative self-sorting principle.
Material discovery by combining stochastic surface walking global optimization with a neural network
A powerful material discovery tool is invented by combining SSW global optimization with neural network computing, which identifies unprecedented TiO2 phases.
Fluorometric probing of the lipase level as acute pancreatitis biomarkers based on interfacially controlled aggregation-induced emission (AIE)
We demonstrate a sensitive, easy and fast method for the fluorometric probing of the lipase level as acute pancreatitis biomarkers based on the novel interfacially controlled aggregation-induced emission (AIE) mechanism.
Nanoscale metal–organic frameworks coated with poly(vinyl alcohol) for ratiometric peroxynitrite sensing through FRET
This work describes a facile yet powerful approach to energy-transfer NMOF (nanoscale metal–organic framework) fabrication for ratiometric peroxynitrite (ONOO−) sensing.
Characterization of the flavoenzyme XiaK as an N-hydroxylase and implications in indolosesquiterpene diversification
Flavoenzymes are ubiquitous in biological systems and catalyze a diverse range of chemical transformations.
Tumor microenvironment-triggered fabrication of gold nanomachines for tumor-specific photoacoustic imaging and photothermal therapy
An alpha-cyclodextrin (α-CD)-based gold/DNA nanomachine was developed as a novel theranostic agent for tumor-selective diagnosis and therapy.
An N-nitrosation reactivity-based two-photon fluorescent probe for the specific in situ detection of nitric oxide
An N-nitrosation reactivity-based two-photon fluorescent probe for the specific detection of NO was rationally designed, prepared, and applied in the in situ detection of nitric oxide in ischemia reperfusion injury mouse model under two-photon microscopy for the first time.
Integrative approach for the analysis of the proteome-wide response to bismuth drugs in Helicobacter pylori
An integrative metalloproteomic approach to unveil the role of antimicrobial metals in general using bismuth as an example.
Molecular heterogeneous catalysts derived from bipyridine-based organosilica nanotubes for C–H bond activation
The present study described bipyridine-based organosilica nanotubes with ∼50 nm length; these nanotubes provide highly active and robust molecular iridium heterogeneous catalysts for C–H oxidation of heterocycles and cycloalkanes as well as C–H borylation of arenes.
Supramolecular assembly of a phosphole-based moiety into nanostructures dictated by alkynylplatinum(II) terpyridine complexes through non-covalent Pt⋯Pt and π–π stacking interactions: synthesis, characterization, photophysics and self-assembly behaviors
A new class of platinum(II) terpyridine complexes with a phosphole-derived bridging alkynyl ligand have been prepared.
Two-photon fluorescent probe for revealing drug-induced hepatotoxicity via mapping fluctuation of peroxynitrite
A peroxynitrite-specific two-photon fluorescent probe was developed for revealing drug-induced hepatotoxicity using peroxynitrite as a biomarker.
Nuclear-targeted siRNA delivery for long-term gene silencing
A nuclear-targeted siRNA delivery system was developed for long-term gene silencing in cancer cells. The nanocarrier consists of gold nanoparticles, synthetic siRNAs and nuclear localization signal peptides.
Contact electrification induced interfacial reactions and direct electrochemical nanoimprint lithography in n-type gallium arsenate wafer
We demonstrated contact electrification induced interfacial redox reactions and developed a direct electrochemical nanoimprint lithography method applicable to crystalline semiconductors.
Supramolecular assembly of platinum-containing polyhedral oligomeric silsesquioxanes: an interplay of intermolecular interactions and a correlation between structural modifications and morphological transformations
POSS-functionalized platinum(II) complexes demonstrate systematically controllable morphological transformations through interplay of intermolecular interactions.
Tracking motion trajectories of individual nanoparticles using time-resolved current traces
We report experiments and simulations demonstrating that multiple distinct motion trajectories of individual nanoparticles can be discerned from time-resolved current traces.
Molecular engineering and sequential cosensitization for preventing the “trade-off” effect with photovoltaic enhancement
Cosensitization of two dyes with different molecular sizes and photovoltaic characteristics is demonstrated to successfully prevent the “trade-off” effect, leading to an excellent power-conversion efficiency of 10.09% under one-sun and 11.12% under 0.3 sun 4 irradiation.
Photochromic benzo[b]phosphole oxide with excellent thermal irreversibility and fatigue resistance in the thin film solid state via direct attachment of dithienyl units to the weakly aromatic heterocycle
Direct attachment of a photoactive bis-thienyl unit to benzo[b]phosphole oxide has led to a new photochromic compound that shows excellent performance in ambient thin film conditions.
The opposite effects of sodium and potassium cations on water dynamics
Water rotational dynamics in NaSCN and KSCN solutions at a series of concentrations are investigated using femtosecond infrared spectroscopy and theory.
Carbogenic nanodots derived from organo-templated zeolites with modulated full-color luminescence
Dual modulated luminescence of carbogenic nanodots derived from zeolites has been acquired by controlling the concentration and pH value of CND aqueous dispersions.
About this collection
In celebration of Chinese New Year, we are delighted to present a special collection of articles by authors in China. This collection of popular articles highlights important contributions from China in a range of fields including analytical science, bioinorganic, catalysis, chemical biology, environmental and sustainable chemistry, materials science, organic chemistry, physical chemistry and supramolecular chemistry. We would like to wish everyone a Happy Chinese New Year!