Celebrating the 30th anniversary of a pioneering microfluidics paper
We mark the 30th anniversary of the Science paper by Harrison et al. that is often credited for helping establish microfluidics as a research field.
Room-temperature bonding of glass chips via PTFE-assisted plasma modification for nanofluidic applications
Establishment of fluorinated glass surfaces via a PTFE-assisted plasma modification strategy for room-temperature bonding of nanofluidic chips.
3D printed porous membrane integrated devices to study the chemoattractant induced behavioural response of aquatic organisms
3D printing of membrane-integrated devices for chemotaxis studies of aquatic animals.
Paper
A rotationally-driven dynamic solid phase sodium bisulfite conversion disc for forensic epigenetic sample preparation
An alternative method for epigenetic sample preparation by a rotationlly-driven, microfluidic sodium bisulfite conversion system for up to four samples in parallel.
Paper
Two-stage tuberculosis diagnostics: combining centrifugal microfluidics to detect TB infection and Inh and Rif resistance at the point of care with subsequent antibiotic resistance profiling by targeted NGS
Two-stage tuberculosis diagnostics from a single sample.
Simple droplet microfluidics platform for drug screening on cancer spheroids
A novel microfluidics platform is introduced for generating tumoroids in droplets, enabling effective drug screening of chemotherapies on both cancer cell lines and patient-derived xenografts.
Fabrication of a self-assembled and vascularized tumor array via bioprinting on a microfluidic chip
This paper describes a novel integrative technology to fabricate a self-assembled and vascularized tumor array via bioprinting on a microfluidic chip for the recreation of a tumor microenvironment.
Simple modification to allow high-efficiency and high-resolution multi-material 3D-printing fabrication of microfluidic devices
We present a multi-material DLP 3D printer containing a vat inclination system and peristaltic pumps for resin replacement and vat cleaning. With this system, it is possible to produce microfluidic devices containing microchannels as narrow as 43 μm.
Modular droplet injector for sample conservation providing new structural insight for the conformational heterogeneity in the disease-associated NQO1 enzyme
A 3D-printed modular droplet injector successfully delivered microcrystals of human NAD(P)H:quinone oxidoreductase 1 (NQO1) and phycocyanin with electrical stimulation in a serial crystallography experiment at 120 Hz repetition rate.
Microfluidic viscometer by acoustic streaming transducers
We introduce μVAST, a high-throughput acoustic microstreaming platform using second-order microstreaming to induce fluid transport and measure the viscosity of 16 samples, automating process flows in drug development, materials manufacturing and production.
Paper
Towards an active droplet-based microfluidic platform for programmable fluid handling
We present a microfluidic platform that combines the capabilities of valve-based microfluidics with droplet-based sample compartmentalization to realize programmable fluid handling.
Sub-nL thin-film differential scanning calorimetry chip for rapid thermal analysis of liquid samples
The first DSC chip that features thin-film enclosures, very low-addenda heat capacity, low residual heat conduction, and rapid response for analyzing liquids.
Paper
Laser-assisted protein micropatterning in a thermoplastic device for multiplexed prostate cancer biomarker detection
We introduce a thermoplastic microfluidic device for the detection of cancer biomarkers by competitive immunoassays. Immobilization of different antibody-protein pairs is achieved by laser-assisted protein adsorption by photobleaching.
Paper
Enhanced podocyte differentiation and changing drug toxicity sensitivity through pressure-controlled mechanical filtration stress on a glomerulus-on-a-chip
The development of a filtration flow device system with precisely controlled pressure revealed the mechanobiology of filtration flow to podocytes regarding morphological and gene expression maturation and increased sensitivity to toxic drugs.
Paper
Multiplexed fluidic circuit board for controlled perfusion of 3D blood vessels-on-a-chip
We developed a fluidic circuit board for simultaneous perfusion of up to twelve 3D vessels-on-a-chip under comparable wall shear stress using a single set of control parameters despite high intrinsic sample diameter variation.
About this collection
In celebration of Andreas Manz, the founding Editorial Board Chair of Lab on a Chip, and in recognition of his recent retirement, we are delighted to announce the publication of a series of select papers. These contributions, invited from his extensive network of esteemed colleagues, showcase the range of impactful work that continues to define the journal — an initiative that Andreas pioneered in 2001.
This special collection is a tribute to his visionary contributions to the µTAS field and his remarkable leadership within the Lab on a Chip community over several decades.
We invite you to explore these exceptional papers and Editorials. Please join us in extending warm wishes to Andreas for a joyful and fulfilling retirement!