Polyphenols and health
Kevin Croft and Cesar Fraga introduce the Food & Function themed collection for the International Conference on Polyphenols and Health (ICPH2019).
Insights into the potential benefits of black soybean (Glycine max L.) polyphenols in lifestyle diseases
Black soybean (Glycine max L.), a cultivar containing abundant polyphenols in its seed coat such as anthocyanins and flavan-3-ols, has been reported to possess various health benefits toward lifestyle diseases.
An overview and update on the epidemiology of flavonoid intake and cardiovascular disease risk
Higher intakes of flavonoid-rich foods are associated with a lower risk of cardiovascular disease in prospective cohort studies.
The effects of betalain-rich cacti (dragon fruit and cactus pear) on endothelial and vascular function: a systematic review of animal and human studies
This systematic review assesses the evidence for the effects of edible cacti (dragon fruit and cactus pear) on vascular and endothelial function based on animal models and human studies.
Anti-stress effects of polyphenols: animal models and human trials
Relationship between “stressors” and “stress responses”, such as hormone secretion. Some polyphenols can prevent stress responses, which subsequently prevent stress-related health problems.
Protection against developing type 2 diabetes by coffee consumption: assessment of the role of chlorogenic acid and metabolites on glycaemic responses
Coffee chlorogenic acids do not affect carbohydrate digestion directly, but modulate glucose absorption/utilisation, the latter through endogenous/gut microbiota metabolites.
Citrus flavanone metabolites protect pancreatic-β cells under oxidative stress induced by cholesterol
Flavanone metabolites decreased the oxidative biomarkers and this effect might be associated with the anti-apoptotic and antioxidant properties of these compounds as well their ability to prevent mitochondrial and insulin secretion dysfunction.
Phenolic composition of 91 Australian apple varieties: towards understanding their health attributes
Apples, an important contributor to total dietary phenolic intake, are associated with cardiovascular health benefits.
Metabolism of different dietary phenolic compounds by the urolithin-producing human-gut bacteria Gordonibacter urolithinfaciens and Ellagibacter isourolithinifaciens
Gordonibacter urolithinfaciens and Ellagibacter isourolithinifaciens are two human gut bacterial species that convert ellagic acid into urolithins. They also convert phenolics by that remove hydroxyls from catechol groups and reduce double bonds by hydrogenation.
Tropical foods as functional foods for metabolic syndrome
Tropical foods are an integral part of the traditional diet and form part of traditional medicine in many countries.
Roasting carob flour decreases the capacity to bind glycoconjugates of bile acids
Carob is the fruit obtained from Ceratonia siliqua L. and it is a source of bioactive compounds that have been linked to several health promoting effects, including lowering blood cholesterol concentration.
(−)-Epicatechin protects thoracic aortic perivascular adipose tissue from whitening in high-fat fed mice
Dietary (−)-epicatechin supplementation leads to the attenuation of the expansion and whitening of thoracic aorta perivascular adipose tissue, affording a crucial strategy to maintain a healthy vasculature.
Tea polyphenols as a strategy to control starch digestion in bread: the effects of polyphenol type and gluten
Mechanisms to slow down starch digestion – tea polyphenols interact with α-amylase and starch during co-digestion of tea extract and bread.
Effects of the apple matrix on the postprandial bioavailability of flavan-3-ols and nutrigenomic response of apple polyphenols in minipigs challenged with a high fat meal
Food matrix interactions with polyphenols can affect their bioavailability and as a consequence may modulate their biological effects.
Systematic bioinformatic analysis of nutrigenomic data of flavanols in cell models of cardiometabolic disease
Flavanol intake positively influences cardiometabolic health in humans – evidence from in vitro nutrigenomic studies.
(−)-Epicatechin mitigates high fat diet-induced neuroinflammation and altered behavior in mice
(−)-Epicatechin improves memory in high fat diet-induced obese mice in association with prevention of endotoxemia and mitigation of neuroinflammation.
Kinetic profile and urinary excretion of phenyl-γ-valerolactones upon consumption of cranberry: a dose–response relationship
Cranberries are a rich source of poly(phenols), mainly monomeric and oligomeric flavan-3-ols. The metabolism of their main colonic compounds has been assessed.
Bioavailability of red wine and grape seed proanthocyanidins in rats
This study explored plasma levels and urinary and fecal excretion of metabolites and microbial-derived catabolites over a 24 h period following the ingestion of red wine (RWP) or grape seed (GSP) proanthocyanidin-rich extracts by rats.
Reliable, accessible and transferable method for the quantification of flavanols and procyanidins in foodstuffs and dietary supplements
Liquid chromatography coupled with fluorescence detection for accurate and precise determination of cocoa flavanol monomers and procyanidins in cocoa-based products.
(−)-Epicatechin administration protects kidneys against modifications induced by short-term L-NAME treatment in rats
(−)-Epicatechin mitigates NO-mediated impairment of kidney function due to its capacity to modulate NOXs, NOSs, and consequently oxidative stress, and NO bioavailability in the renal cortex of L-NAME treated rats.
Dose–response relationship between cocoa flavanols and human endothelial function: a systematic review and meta-analysis of randomized trials
This systematic review with meta-analysis provides evidence that cocoa flavanols could significantly improve endothelial function, with an optimal effect observed with 710 mg total flavanols, 95 mg (−)-epicatechin or 25 mg (+)-catechin.
About this collection
This is a collection of papers consisting of invited contributions from the 9th International Conference on Polyphenols and Health, held in Kobe, Japan, 28 Nov-1-Dec 2019. Guest Edited by Kevin Croft and Cesar Fraga. New articles will be added to this collection as they are published.