vibrational circular dichroism by manipulation of the electronic manifold
Manipulating the electronic manifold of an organic compound by electrochemical reduction leads to an order of magnitude enhancement of vibrational circular dichroism signals.
cytochrome c states – TERS studies of whole mitochondria
Tip-enhanced Raman spectroscopy reveals structural changes of cytochrome c in fixed mitochondria with nanometre resolution. Oxidation and spin-state changes of the heme can be clearly distinguished.
Experimental and theoretical investigations on the negative influence of an applied magnetic field on
SERS of Ag nanoparticles
The presence of a magnetic field could lead to reducing electrons on the surface of Ag nanoparticles and a broadened energy gap, which could reduce surface plasma and charge transfer and thus decrease the SERS intensity.
Detection of viral nucleoprotein binding to anti-influenza aptamersviaSERS
SERS can directly detect the binding of influenza nucleoproteins isolated from a commercial flu vaccine to an anti-influenza aptamer, confirming its applicability to viral diagnostics.
Fluctuations of the Stokes and anti-Stokes surface-enhanced resonance Raman scattering intensities in an electrochemical environment
Distributions of the anti-Stokes to Stokes ratios were obtained. The tailed distributions measured in the “single molecule” regime depended on the applied potential and they were correlated to the different resonance energies of the SERRS hot spots.
SERS from molecules bridging the gap of particle-in-cavity structures
By combining silver nanoparticles and gold SSV substrates, SERS is obtained from molecules that bridge the particle–cavity gap.
Clean and modified substrates for direct detection of living cells by surface-enhanced Raman spectroscopy
SERS substrates treated by iodide adsorption or electrochemical negative potential desorption provide a good reproducibility for studying living cells.
DNA detection using enzymatic signal production and SERS
The sensitive and selective detection of DNA by surface enhanced resonance Raman scattering spectroscopy (SERS) via enzymatic signal release.
Use of a hydrogel
polymer for reproducible surface enhanced Raman optical activity (SEROA)
The first confirmation of surface enhanced Raman optical activity (SEROA) through measurement of mirror image bands for D- and L-ribose. This was achieved by employing a gel forming polyacrylic acid to control colloidal aggregation and the associated birefringent artefacts.
Polarization characteristics of surface-enhanced Raman scattering from a small number of molecules at the gap of a metal nano-dimer
The orientation of the molecule at the metal nanogap affects the polarization of the Raman scattered photons.
SERS active silica coated silver nanoparticles
Tri-functional molecules have been synthesised to stabilise Ag nanoparticle cores, act as a resonance Raman reporter and provide a precursor for an integrated network of silica polymers via Stöber condensation.
Modification of Ag
nanoparticles with mixed thiols for improved SERS detection of poorly adsorbing target molecules: detection of MDMA
The surface of a silver colloid has been modified with a mixed thiol monolayer whose composition was tuned to promote MDMA adsorption and thus allow quantitative SERS detection of “Ecstasy”.
Surface-enhanced Raman scattering from helical silver
Helical silver nanorod arrays are designed by oblique angle deposition and their surface-enhanced Raman scattering properties are characterized. The potential SERS mechanism is proposed.
SERS spectroscopy and SERS imaging of Shewanella oneidensis using silver nanoparticles and nanowires
Surface Enhanced Raman Scattering (SERS) and SERS imaging of Shewanella oneidensis using silver nanoparticles and silver nanowires as metallic substrates.
Hydrophilically stabilized gold nanostars as
SERS labels for tissue imaging of the tumor suppressor p63 by immuno-SERS microscopy
Gold nanostars covered with a self-assembled monolayer of glycol-modified Raman reporter molecules were used for imaging of the target protein p63 in prostate biopsies.
How the electrode potential controls the selection rules of the charge transfer mechanism of SERS
Resonant SERS-CT intensities have been estimated from the properties of S0–CTi transitions of selected [Agn–pyridine]q and [Agn–pyrazine]q complexes.
Modelling the effect of the electrode potential on the metal–adsorbate surface states: relevant states in the charge transfer mechanism of SERS
Quantum mechanical calculations of the ground and excited electronic states of [Agn–pyridine]q complexes yield a linear dependence of the energies of the metal-to-molecule CTi charge transfer states on qeff = q/n.
Magnetic separation and immunoassay of multi- antigen based on surface enhanced Raman spectroscopy
A novel and highly sensitive magnetic separation immunoassay method based on surface enhanced Raman spectroscopy (SERS) has been developed.
SERS from aluminium nanohole arrays in the ultraviolet region
Ordered Al nanohole arrays for tunable UV-SERS are theoretically proposed and simulated. The SERS enhancement factor as high as 5 to 6 orders of magnitude is attained in the optimal geometry.
SERS into the infrared with gold nanosphere dimers
We show that dimers of gold spheres exhibit the largest SERS enhancements at near-IR wavelengths.
Experimental demonstration of surface selection rules for
SERS on flat metallic surfaces
Surface selection rules are revealed in the angular and polarization dependence of the SERS signal from Nile Blue molecules on a flat metal film, in the spirit of the original proposal.
Analysis of excitation laser intensity dependence of blinking
SERRS of thiacarbocyanine adsorbed on single silver nanoaggregates by using a power law with an exponential function
In blinking SERRS, truncation in a power-law that reproduces probability distributions of the dark events (Poff) against their duration occurred at the same times despite the change of excitation laser intensity.
Evidence of a surface plasmon-mediated mechanism in the generation of the SERS background
SERS imaging on the surface of nanostructured metallic films of controlled morphology uncovers the mechanism generating the SERS background enhancement.
Efficient disc on pillar substrates for surface enhanced Raman spectroscopy
Pillar-like structures created using electron beam lithography are mapped using surface enhance Raman spectroscopy (SERS) and achieve enhancement factors greater than 1 × 109. These novel substrates allow for sensitive real-time analysis of various analytes and are reusable.
Localized and propagating surface plasmon co-enhanced
Raman spectroscopy based on evanescent field excitation
LSP/PSP co-enhanced SERS was obtained based on evanescent field excitation and the maximal SERS signal appeared at the SPR angle.
Correlated AFM and
SERS imaging of the transition from nanotriangle to nanohole arrays
Correlated AFM and Raman imaging provided novel experimental proof that hot spots are located on Ag islands for nanotriangle arrays and in the core area of the hole for nanohole arrays.
nanoparticles with tunable optical properties for selective protein analysis
Ag nanoparticles with controlled optical properties and biocompatible coatings are used to probe cofactor–protein complexes by SERR spectroscopy. The particles were optimised with respect to maximum signal enhancement and structural preservation of the protein cytochrome c.
Essential nanogap effects on surface-enhanced Raman scattering signals from closely spaced gold nanoparticles
Essential nanogap effects on surface-enhanced Raman scattering signals obtained from two diagonally aligned gold nanoparticles with several nanometre separations were elucidated.
Multiplex cancer cell detection by
SERS nanotags with cyanine and triphenylmethine Raman reporters
SERS nanotags have been prepared to accomplish the multiplex detection of cancer cells. Herein we evaluated the adequacy of lipoic acid-containing cyanine derivatives (Cy3LA and Cy5LA) to function as multiplex partners with triphenylmethine core (B2LA) under single excitation wavelength.
Differential separation of
protein mixtures using convective assembly and label-free detection with surface enhanced Raman scattering
Differential separation of protein mixtures with convective-assembly and detection with SERS.
New insights on the Aucore/Ptshellnanoparticle structure in the sub-monolayer range:
SERS as a surface analyzing tool
SERS study of the core–shell structural evolution of Au@Pt nanoparticles: the templating role of the Au atoms on the nanoscale Pt-phase structure in the sub-monolayer range.
silver nanoparticles: alkyne-functionalized ligands for SERS imaging of mammalian cells
New reporter molecules for SERS imaging are accessed via alkyne functionalized nanoparticles and used to image cell surface receptors.
Raman and computational study of solvation and chemisorption of
thiazole in silver hydrosol
A SERS investigation is combined with ab initio computational analysis for thiazole in Ag hydrosol, where solvation and chemisorption competitively occur.
Surface-enhanced Raman scattering with silver
nanostructures generated in situ in a sporopollenin biopolymer matrix
Silver nanoparticles embedded in the ultrastructure of the pollen outer shell enable vibrational spectroscopic access to the sporopollenin biopolymer.
A new strategy to prepare surface-enhanced Raman scattering-active substrates by electrochemical pulse deposition of gold nanoparticles
We develop a simple pathway to prepare effectively SERS-active substrates with Au nanoparticles by an electrochemical strategy of deposition–dissolution cycles.
Photon-driven charge transfer and photocatalysis of p-aminothiophenol in metal nanogaps: a DFT study of SERS
Our DFT calculations show that surface photocatalytic coupling reactions yield a new surface species of p,p′-dimercaptoazobenzene (DMAB) causing the significant change in the SERS spectra from p-aminothiophenol (PATP) on silver and gold nanogaps.
Scanned chemical enhancement of surface-enhanced Raman scattering using a charge-transfer complex
We find the nontotally symmetric b2 modes are selectively enhanced in the SERS spectrum and represent a laser wavelength-dependent property.
nanoparticle based SERS from hydrogen adsorbed on a rhodium(111) electrode
The first in situ surface Raman spectra of hydrogen on rhodium under electrochemical conditions using Au@Rh and Au@SiO2 NPs.
Surface-enhanced Raman scattering of
4-aminobenzenethiol on gold: the concept of threshold energy in charge transfer enhancement
Some threshold energy is required for 4-aminobenzenethiol to occupy the chemical enhancement sites on gold.
Protein– ligand binding investigated by a single nanoparticle TERS approach
Detecting a single nanoparticle by TERS gives rise to a Raman spectrum characteristic of the ligand on the nanoparticle and the target protein, enabling nanoscale spectroscopic imaging of protein–ligand binding.
SERS of an insoluble synthetic organic pigment-quinacridone quinone-employing calixarenes as dispersive cavitands
A new and smart approach to get SERS spectra of insoluble compounds. The SERS of quinacridone quinone hosted by calixarenes as a case study.
About this collection
Surface Enhanced Raman Spectroscopy (SERS) is currently enjoying exponential exposure in terms of publications and there are some highly innovative approaches now being investigated to harness the power of this phenomenon. To recognise and further promote this, in this web-based thematic issue, ChemComm is showcasing research by prominent scientists working on SERS and its applications.
The guest editors of this issue are Duncan Graham, Zhongqun Tian and Richard Van Duyne.
Articles in this web themed issue will be added to the list below as soon as possible, after they are published. Please return to this page frequently to see this collection grow.