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Issue 12, 2011
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Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters

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Abstract

SERS nanotags have been prepared to accomplish the multiplex detection of cancer cells. Herein we evaluated the adequacy of lipoic acid-containing cyanine derivatives (Cy3LA and Cy5LA) to function as multiplex partners with a triphenylmethine Raman reporter (B2LA) under a single excitation wavelength. SERS experiments enabled the multiplex recognition of two different cancer cells with antibody-conjugated nanotags that were derivatized with optimized cyanine and triphenylmethine reporters.

Graphical abstract: Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters

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Article information


Submitted
30 Nov 2010
Accepted
15 Jan 2011
First published
09 Feb 2011

Chem. Commun., 2011,47, 3514-3516
Article type
Communication

Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters

K. K. Maiti, A. Samanta, M. Vendrell, K. Soh, M. Olivo and Y. Chang, Chem. Commun., 2011, 47, 3514
DOI: 10.1039/C0CC05265E

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