Themed collection Biomaterials Science Most Popular 2022
Applications of metal–phenolic networks in nanomedicine: a review
In this paper, the assembly process and the material properties of MPNs are discussed, and the application scope and prospect of MPNs are clarified. This paper provides new ideas for the construction of nanoplatforms for therapeutics and diagnostics.
Porous organic polymers for drug delivery: hierarchical pore structures, variable morphologies, and biological properties
Porous organic polymers have received considerable attention in recent years because of their applicability as biomaterials.
Design and structural regulation of AIE photosensitizers for imaging-guided photodynamic anti-tumor application
Aggregation-induced emission (AIE) photosensitizers (PSs) are promising anti-tumor materials in photodynamic therapy.
Construction of multifunctional wound dressings with their application in chronic wound treatment
Multifunctional wound dressings or smart dressings with pro-angiogenic function, antibacterial properties, anti-inflammatory/antioxidant activity and tissue adhesion for chronic wound repair.
Pre-clinical non-viral vectors exploited for in vivo CRISPR/Cas9 gene editing: an overview
Non-viral delivery technologies for efficient in vivo Clustered Regulatory Interspaced Short Palindromic Repeats (CRISPR/Cas9) gene editing.
Articulation inspired by nature: a review of biomimetic and biologically active 3D printed scaffolds for cartilage tissue engineering
The tissue engineering triad of biomaterials, cells and therapeutics as it applies to the formulation of biomimetic bioinks for cartilage repair. These bioinks can be functionalised with cells or cellular therapeutics to promote cartilage repair.
Superparamagnetic iron oxide nanoparticles for magnetic hyperthermia: recent advancements, molecular effects, and future directions in the omics era
Coating and targeting strategies improve superparamagnetic iron oxide nanoparticles-induced hyperthermia, while omics can unveil molecular effects.
Non-viral delivery of the CRISPR/Cas system: DNA versus RNA versus RNP
Delivery of the CRISPR/Cas9 system can be realized by utilizing different biomolecular formats, each featuring individual characteristics, advantages and challenges.
Intestinal models based on biomimetic scaffolds with an ECM micro-architecture and intestinal macro-elasticity: close to intestinal tissue and immune response analysis
Intestinal epithelium models based on biomimetic scaffolds with an ECM micro-architecture and intestinal macro-elasticity are close to their counterpart intestinal tissues, serving as powerful in vitro tools to assess the immunobiotics–host interactions.
A high-throughput 3D bioprinted cancer cell migration and invasion model with versatile and broad biological applicability
A HTP 3D bioprinted cell migration platform that has broad applications across quantitative cell and cancer biology as well as drug screening.
Soluplus®-based dissolving microarray patches loaded with colchicine: towards a minimally invasive treatment and management of gout
Colchicine-Soluplus® was loaded into dissolving microarray patches for a new minimally-invasive alternative strategy for management of acute gout.
Facile preparation of PVA hydrogels with adhesive, self-healing, antimicrobial, and on-demand removable capabilities for rapid hemostasis
A novel PBO hydrogel based on PVA, borax and oligomeric procyanidin was designed with adhesive, self-healing, antimicrobial, and on-demand removable capabilities for rapid hemostasis.
High-efficiency brain-targeted intranasal delivery of BDNF mediated by engineered exosomes to promote remyelination
The schematic illustration of the effect of the brain-targeted engineered exosome-mediated BDNF on oligodendrocyte differentiation in vitro and remyelination in vivo through intranasal administration.
mRNA-carrying lipid nanoparticles that induce lysosomal rupture activate NLRP3 inflammasome and reduce mRNA transfection efficiency
We have demonstrated the ability of mRNA-carrying lipid nanoparticles to activate NLRP3 inflammasomes is highly dependent on lipid composition, affecting the endo/lysosomal rupture or calcium influx/mitochondrial ROS production by the nanoparticle.
Modular mixing of benzene-1,3,5-tricarboxamide supramolecular hydrogelators allows tunable biomimetic hydrogels for control of cell aggregation in 3D
Dynamic hydrogels can allow cells to form complex multicellular aggregates. Herein, we show that the dynamics of the hydrogel environment can directly influence the speed and size of cellular aggregates formed by using a modularly tunable supramolecular hydrogel.
An aza-BODIPY-based NIR-II luminogen enables efficient phototheranostics
A new aza-BODIPY-based NIR-II luminogen enables efficient phototheranostics.
In vivo delivery of plasmid DNA by lipid nanoparticles: the influence of ionizable cationic lipids on organ-selective gene expression
Not all ionizable lipids are the same – choosing the right one is critical to the success of lipid nanoparticles for different applications.
Curcumin doped zeolitic imidazolate framework nanoplatforms as multifunctional nanocarriers for tumor chemo/immunotherapy
A novel curcumin doped zeolitic imidazolate framework nanoplatform was synthesized by a metal coordination strategy, which could effectively improve the application of curcumin in tumor therapy and improve anti-tumor immunity.
Investigation and comparison of resin materials in transparent DLP-printing for application in cell culture and organs-on-a-chip
Transparent, cytocompatible and high resolution 3D-DLP-printing offers new opportunities in cell culture and organs-on-a-chip.
Ultrahigh SERS activity of the TiO2@Ag nanostructure leveraged for accurately detecting CTCs in peripheral blood
Accurately recognizing CTCs in peripheral blood based on the TiO2@Ag–R6G–rBSA–FA SERS bioprobe is carefully verified by in situ immunofluorescence staining experiments, which directly supports the CTC detection accuracy of the SERS strategy.
About this collection
This online collection features some of the most cited, most downloaded and most shared articles published in Biomaterials Science during 2022.
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