Themed collection Biomaterials Science 10th Anniversary: Top papers from China

15 items
Minireview

Advances in crosslinking strategies of biomedical hydrogels

This review presents the commonly used crosslinking methods for hydrogel synthesis and summarizes the current status and discusses future perspectives.

Graphical abstract: Advances in crosslinking strategies of biomedical hydrogels
Review Article

Rational design and latest advances of polysaccharide-based hydrogels for wound healing

This review presented the crucial design considerations and current state of polysaccharide-based hydrogels as wound dressings. The commonly used crosslinking techniques are also discussed in detail.

Graphical abstract: Rational design and latest advances of polysaccharide-based hydrogels for wound healing
Review Article

Strategies for transporting nanoparticles across the blood–brain barrier

Nanoparticles have been widely deployed for brain-targeted delivery. Drugs can be embedded either in a matrix or deposited on the surface of nanoparticles, and the whole particle can cross the BBB effectively and be targeted to specific parts of the body in a controllable manner.

Graphical abstract: Strategies for transporting nanoparticles across the blood–brain barrier
Paper

3D printed gelatin/hydroxyapatite scaffolds for stem cell chondrogenic differentiation and articular cartilage repair

The hUCB-MSC-laden 3D printed gelatin/HAP scaffold effectively repairs knee cartilage defects in a pig model.

Graphical abstract: 3D printed gelatin/hydroxyapatite scaffolds for stem cell chondrogenic differentiation and articular cartilage repair
Paper

Antibacterial and hydroxyapatite-forming coating for biomedical implants based on polypeptide-functionalized titania nanospikes

The immobilization of mussel-inspired polypeptide onto biomimetic titania nanospike coating enhanced its antibacterial ability and bioactivity, thus holding great promise for utilization for orthopedic and dental implants.

Graphical abstract: Antibacterial and hydroxyapatite-forming coating for biomedical implants based on polypeptide-functionalized titania nanospikes
Paper

Doxorubicin-loaded nanoscale metal–organic framework for tumor-targeting combined chemotherapy and chemodynamic therapy

DMH NPs were prepared and could effectively induce MCF-7 cell death through the combination of chemotherapy and chemodynamic therapy.

Graphical abstract: Doxorubicin-loaded nanoscale metal–organic framework for tumor-targeting combined chemotherapy and chemodynamic therapy
Paper

Tannic acid-loaded mesoporous silica for rapid hemostasis and antibacterial activity

The as-prepared tannic acid (TA)-load mesoporous silica via electrostatic adsorption (TMS) exhibited excellent hemorrhage control by both TA-induced faster blood contact and plasma protein crosslinking, and MS-initiated water absorption, blood components concentration and coagulation factors activation, and good antibacterial properties.

Graphical abstract: Tannic acid-loaded mesoporous silica for rapid hemostasis and antibacterial activity
Paper

Noninvasive rapid bacteria-killing and acceleration of wound healing through photothermal/photodynamic/copper ion synergistic action of a hybrid hydrogel

Bacterial infection often delays healing of wounded tissues and so it is essential to improve the antibacterial efficiency in situ.

Graphical abstract: Noninvasive rapid bacteria-killing and acceleration of wound healing through photothermal/photodynamic/copper ion synergistic action of a hybrid hydrogel
Paper

Tuning protein assembly pathways through superfast amyloid-like aggregation

Three structural elements for protein assembly are proposed, which guide superfast amyloid-like globular protein aggregation towards macroscopic nanofilms and microparticles.

Graphical abstract: Tuning protein assembly pathways through superfast amyloid-like aggregation
Paper

Simultaneous detection of multiple viruses based on chemiluminescence and magnetic separation

In this report, a DNA hybridization based chemiluminescent detection method has been proposed for reliable detection of multiple pathogens. The use of surface modified magnetic nanoparticles can help to integrate this system into an automated platform for high throughput applications.

Graphical abstract: Simultaneous detection of multiple viruses based on chemiluminescence and magnetic separation
Paper

Preparation of pH-responsive mesoporous hydroxyapatite nanoparticles for intracellular controlled release of an anticancer drug

A well-defined core–shell nano-carrier (PAA–MHAPNs) was successfully synthesized based on a graft-onto method by using mesoporous hydroxyapatite nanoparticles (MHAPNs) as the core and polyacrylic acid (PAA) as the shell.

Graphical abstract: Preparation of pH-responsive mesoporous hydroxyapatite nanoparticles for intracellular controlled release of an anticancer drug
Paper

A combination of tri-modal cancer imaging and in vivo drug delivery by metal–organic framework based composite nanoparticles

A facile method was developed for the synthesis of multifunctional Fe3O4@PAA/AuNCs/ZIF-8 NPs. Furthermore, the obtained NPs with ultrahigh drug storage capacity and dual pH-responsive drug release properties were applicable in simultaneous tri-modal.

Graphical abstract: A combination of tri-modal cancer imaging and in vivo drug delivery by metal–organic framework based composite nanoparticles
Paper

Graphene film doped with silver nanoparticles: self-assembly formation, structural characterizations, antibacterial ability, and biocompatibility

Reduced graphene oxide film decorated with silver nanoparticles shows enhanced antibacterial activity and improved biocompatibility.

Graphical abstract: Graphene film doped with silver nanoparticles: self-assembly formation, structural characterizations, antibacterial ability, and biocompatibility
Paper

Biologically inspired membrane design with a heparin-like interface: prolonged blood coagulation, inhibited complement activation, and bio-artificial liver related cell proliferation

A blood-contact membrane with a heparin-like interface was designed with prolonged blood coagulation, inhibited complement activation and excellent liver cell proliferation.

Graphical abstract: Biologically inspired membrane design with a heparin-like interface: prolonged blood coagulation, inhibited complement activation, and bio-artificial liver related cell proliferation
Paper

Study on effective extraction of chicken feather keratins and their films for controlling drug release

Keratin was extracted from chicken feathers, and applied to prepare keratin films which were pH-responsive and showed controllable drug-release behavior.

Graphical abstract: Study on effective extraction of chicken feather keratins and their films for controlling drug release
15 items

About this collection

This online collection features some of the most cited, most downloaded and most shared articles from China published in Biomaterials Science during the first 10 years of the journal.

Congratulations to all the authors whose articles are featured and thank you to all our authors, reviewers and readers for your ongoing support.


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